RNF111
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
UBC
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
SMURF2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
FHL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18157088
6492033
|
SMURF2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
8308197
22045334
|
AXIN1
|
RNF111
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
AXIN1
|
SMAD7
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
CREB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16862174
|
CREB1
|
SMAD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20864035
|
RNF111
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
8153045
21516116
|
CSNK2A1
|
RNF111
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
KHDRBS1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF111
|
KRTAP5-9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
UBC
|
NEDD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
UBE2I
|
SKIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TGFB1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21358634
9679059
|
UBC
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8308197
22045334
|
SMAD3
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8308197
22045334
|
SMAD7
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
UBE2N
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22661230
22635276
|
SUMO3
|
SUMO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11451954
17938407
|
UBE2N
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22661230
22635276
|
UBE2I
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17693435
16030353
|
UBE2V1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213148
11057907
|
SMURF2
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217094
15231748
|
UBE2N
|
UBE2V1
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
AXIN1
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20128690
22682247
|
SMAD3
|
NR4A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33990575
21988832
|
PML
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
15356634
|
UBA1
|
UBE2E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
UBA1
|
UBE2G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
TRIM21
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
NEDD4
|
UBA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18287095
18498243
|
CSNK2A1
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
SKI
|
SKIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
AXIN1
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18632848
26871637
22509369
|
RNF111
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
TRIM21
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
UBA1
|
UBE2D4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
NEDD4
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
SMAD7
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18593713
16601693
|
SMAD3
|
NEDD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19953087
15496141
21685363
32296183
|
SUMO1
|
SUMO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24654937
25027693
17938407
21098080
15576338
|
TRIM8
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
UBA1
|
UBE2W
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
SUMO2
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25027693
21148299
23543742
17000644
20797634
22155184
21779164
19553342
9452416
17081986
16713569
24637324
21693764
19471022
21252943
15940266
16189514
22578841
20826694
24190887
28851805
|
SMAD7
|
SMAD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26555259
9256479
|
LRSAM1
|
TSG101
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
TRIM8
|
UBE2D4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
SMURF2
|
SMAD7
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
18448069
|
SMAD7
|
SMURF2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
19352540
|
UBC
|
UBE2G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
NEDD4
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
NR4A1
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12032831
16713569
16189514
|
SMAD2
|
SKIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
15231748
10531062
11691834
16959829
12764135
12426322
18729074
22442258
25059663
|
SMAD3
|
SKIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15231748
10531062
17469184
11691834
16959829
11306568
12764135
12426322
22442258
|
UBC
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
SKIL
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
UBA1
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
SKIL
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
SMAD2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
TGFB1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
SMURF2
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
AXIN1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16601693
|
SMAD2
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9689110
|
HSP90AB1
|
NR4A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NEDD4
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
SUMO1
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15017387
15561718
28851805
16501610
19217413
22155184
22875967
24654937
31879127
21779164
20188669
9885291
9452416
17081986
21098080
22406621
18625722
21305000
17344210
17027752
11160742
19380586
23604351
23830076
17081985
9427741
11080164
16189514
23028697
21057547
19015637
20972456
8806687
20826694
24190887
25497731
17036045
11948183
9756909
18474224
|
PML
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
PML
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15356634
|
SKIL
|
SKI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
9927733
16959829
12764135
25059663
|
SMAD2
|
SKI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
10485843
19032343
12732634
14699069
17283070
25670202
28468752
26977879
20959473
21149449
12764135
12874272
18729074
22442258
10575014
|
SMAD3
|
SKI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14699069
19032343
12732634
25670202
17283070
17469184
12857746
19875456
12154125
11306568
12874272
12426322
12764135
22442258
14525983
10575014
|
SKI
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15128733
19032343
|
SKIL
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23154975
16442497
|
SMAD2
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
27974707
11456453
16284942
|
SMAD6
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9892110
|
SMAD3
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
UBE2N
|
UBA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
27173435
14517261
29537486
18678647
30097011
27182664
25527291
33619271
31638574
|
UBA1
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
SMURF2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
SMAD2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
SKI
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
NEDD4
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
SKI
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
NEDD4
|
UBE2D3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
TRIM21
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
TRIM21
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
UBA1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
ANAPC11
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
KRTAP5-9
|
LCE4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
UBE2N
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
UBA1
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
UBE2I
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5219915
17491593
|
SUMO3
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
UBC
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
SMAD7
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
UBC
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
PML
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
NEDD4
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
UBA1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.98
|
STRING
|
36370105
|
TSG101
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
SUMO1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
SUMO2
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
UBE2D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
UBC
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
SMAD7
|
SMURF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
26435193
22773947
15231748
23331499
22921829
16641086
17719543
21791611
26679521
11163210
27292644
20937913
15221015
18448069
22624557
32283253
23973329
16061177
14722617
19352540
|
SMURF2
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
35509688
27447855
15221015
11016919
23331499
22045334
18729074
35379779
11389444
19122240
11158580
15231748
14507671
19620243
20937913
|
SMURF2
|
SKIL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11389444
23331499
15221015
|
AXIN1
|
RNF111
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16601693
23331499
14657019
|
AXIN1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11438668
23331499
18988627
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
CSNK2A1
|
PML
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16873060
19380586
|
CSNK2A1
|
HSP90AB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15822905
17081983
16565220
18088087
29854279
2492519
34359868
25995454
1956339
16094384
15581363
18591256
16964243
92065884
15302935
|
LRSAM1
|
TSG101
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15256501
19542561
25416956
18077552
26811492
16189514
32296183
16713569
19549727
|
SUMO1
|
PML
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22875967
9756909
25497731
17036045
21057547
18931695
19217413
8806687
16189514
17081985
11080164
11948183
9885291
19380586
17344210
|
PML
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
15356634
16189514
18988627
|
RNF111
|
SKIL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17591695
17510063
|
RNF111
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
17341133
14657019
18950738
16189514
|
RNF111
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23331499
14657019
|
RNF111
|
SKI
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18451154
17510063
|
RNF111
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
17341133
17510063
|
SKI
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
17145710
12764135
12154125
10485843
23331499
21071413
19049980
12874272
12732634
25670202
14525983
12857746
11306568
12793438
17469184
22442258
19032343
14699069
19875456
10575014
10549282
17283070
12426322
|
SKI
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
12764135
26977879
18729074
20959473
10485843
23331499
21071413
12874272
12732634
25670202
12793438
22442258
21149449
19032343
14699069
10575014
17283070
|
SKIL
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
12764135
15221015
23331499
18729074
22442258
25059663
16959829
18334480
10531062
17510063
15496141
12793438
15231748
11691834
12426322
|
SKIL
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
12764135
23331499
21071413
22442258
11306568
16959829
10531062
12793438
17469184
15231748
11691834
12426322
|
SMAD3
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
9865696
|
SMAD2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
TGFB1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD2
|
SMAD7
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD2
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15183844
10887185
10753944
10843994
10559222
|
SMAD7
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
17438144
21071413
9892009
9892110
|
SMAD6
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
9256479
21071413
9892110
|
TGFB1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15548370
19010789
10678166
16474430
9311995
23831640
17934056
20519943
24075003
11792802
11133108
21900405
14557817
11278410
19920116
9865696
|
SMAD2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21988832
26186194
12543979
9111321
15084259
9311995
25878769
18729074
12700238
|
TGFB1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11279127
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21614932
22331441
23784029
8515656
|
TGFB1
|
SMAD3
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
TGFB1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
SMAD7
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11279127
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21614932
22331441
23784029
8515656
|
SMAD3
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26553048
27974707
10708950
19214138
|
SMAD3
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10823886
15183844
12761881
10887185
10973944
10839991
10753944
10843994
15579469
10559222
|
TGFB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21557273
24899689
24075003
24485922
28756206
32196115
|
SMAD7
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
21071413
9892009
26555259
9892110
|
TGFB1
|
SMAD7
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
SMAD7
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10887185
15855807
9886263
20631490
22656308
19214138
23633623
14600158
10753944
11912247
11385614
11180003
17928287
19010789
22496417
22841502
17074765
15496141
11448947
|
TGFB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
14718519
16474430
17934056
20519943
9335507
21900405
11133108
14557817
15548370
19920116
|
UBE2I
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
21212807
25416956
16713569
18691969
17938407
11735126
25502805
15931224
26496610
16732283
24352468
17353931
18359863
10666456
21174150
8921390
9353268
12924945
21949651
32296183
16524884
17956732
18264111
12764129
10961991
14673145
19684601
17698038
16494873
31515488
23871147
17491593
|
UBE2N
|
UBE2V1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15492226
29662619
10089880
1551980
11057907
16129784
25260751
15147900
22367539
18082144
18678647
26101372
20551964
16307917
17709375
19549727
18029035
21460221
24145445
16215985
20613989
25548215
|
XPC
|
XPC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.23
|
3.22
|
PKG
|
28854368
|