Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CAV1 CAVIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
GOLGA2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TDP2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BTBD2 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
H3C2 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKAP9 GOLGA2 â—¼   COLOCALIZATION 2.0 0.8 intact 7234073 19242490
ANXA1 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
OTUB1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRAF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 DLX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CAV1 TRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213300 11112773
TRAF3 CD40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7527023 5220338
TRAF5 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TFIP11 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TDP2 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 TFIP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBC ICAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17174307 5219467
LMNA PDCD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NFKB1 TAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18694960
PRKCZ NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11684013 12881425
NFKBIA UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219675 17318178
PRKCZ NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12893839 10764587
UBC OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11689694 5214752
OTUB1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
OTUB1 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
PRKCZ RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12881425 5216561
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
UBE2I RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25218447 22649547
SUMO3 RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25218447 22649547
RPS27A TDP2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBE2I SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
VIM SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SKIL TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
TOP2A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18394993 25114211
VIM SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
VIM SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TFIP11 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TDP2 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDP2 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDP2 TFIP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TDP2 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDP2 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21030584
TDP2 TOP2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21030584
UBB TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VIM TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2I TOP2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12832072 10862613
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TDP2 ASAH1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
TDP2 PDCD4 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
TDP2 PRR36 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
OTUB1 TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20622874 34591986 19996094
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MT-CO2 NDUFA4 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
AKAP9 DVL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27107012 34299191
TDP2 CRYM â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
TDP2 ANXA3 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
TDP2 MAPK6 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TDP2 MDK â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
TDP2 AKT1S1 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
TDP2 IGFBP2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
TDP2 ASNS â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
COX6B1 NDUFA4 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SUMO2 SOX6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 16442531
TRAF5 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32296183 9718306 21903422
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
SUMO2 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 18381449 32786267 21252943 20797634 21693764
SUMO2 TOP2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 21252943 21693764
TDP2 EEF2K â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
ATXN3 UBB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
TDP2 TTC38 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TRAF3 TRAF5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CD40 TRAF5 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TNFRSF8 TRAF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
TDP2 CAVIN1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
TRAF2 CAV1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11805080 32041822 16713569 11112773 16189514
TRAF6 TRAF5 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
TRAF5 TRAF6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27107012 32296183 29176576 21516116 25416956 22493164 33539883
TNFRSF1B TRAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SMAD3 SKIL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15231748 10531062 17469184 11691834 16959829 11306568 12764135 12426322 22442258
SKIL SMAD3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TDP2 NES â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
ACVR1B SMAD3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11024047 12063393 14978253
ACVR1B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14517293 23331499 9605406
ANXA1 OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP3K7 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP3K7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9380693
UBA52 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TDP2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MDK MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NFKBIA SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19297320 9734360 11124955
UBE2I PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
SUMO1 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TDP2 LGALS1 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
CD40 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RPS27A TRAF6 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
TDP2 PTGR1 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
TDP2 FLNC â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
ATXN3 RPS27A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TDP2 AHNAK â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
TOP2B TOP2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 22939629 8710863
OTUB1 UBC â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
TDP2 MT-CO2 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
SUMO1 TOP2A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12832072 10862613 19596686 18381449
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SUMO1 TOP2B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15161980 21110914 10862613 15561718 19596686
TDP2 NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
TDP2 CRIP1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
CD40 TRAF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ATXN3 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CD40 TRAF3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TDP2 TCEAL8 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COX6B1 MT-CO2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFKBIA RELA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ACVR1B TDP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18039968
NFKB1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513725 11313274 19164127 11027342 17031478 9733827
RELA CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11313274 17031478 19164127 9733827 10075983
TRAF5 CD40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9990007 20676093 9718306 17332487 8790348 16189514
CD40 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 20614026 17145710 21041727 9133417 7859281 12637493 10352240 16260598 15485859 24810049 17878343 9384571 7530216 12220533 18635759 14517219 9990007 24260396 10428814 17332487 19667091 7533327 9168896 10984535 27716849 9718306 10318845 11562359 7527023
CD40 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 20614026 21041727 9133417 25416956 12637493 10352240 16713569 16260598 15485859 25502805 12220533 18635759 25910212 9990007 17353931 8855313 10428814 21282461 10411888 17332487 32296183 16282325 20676093 19667091 9168896 27716849 20449947 9718306 31515488 10318845 21071692 11562359 9020361
SMAD3 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
ETS1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10942770 12444985 12750007 18374905 12928043
NFKB1 ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 10926553 15480988 9192770 7957928 11198351 19074768 9188493 16317091 17121934 18928584 15843586 22001597 9056676 18285351 16385502 10946302 20103608 10738944 15800027 22708120 9888295 11877286 17855547 10553096 10092659 9733827 11401521 11463837 9916895 20173029 10837365 12691701 16105834 12490396 16453001
RELA ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 10926553 7822333 9192770 9831247 7957928 15996193 22337883 19074768 16778171 9188493 16317091 17121934 18928584 15843586 22001597 9056676 18285351 16385502 10946302 15946255 20103608 10738944 15800027 22708120 23238746 22901690 9888295 11877286 7659084 17855547 10553096 10092659 9733827 11401521 11463837 9916895 20173029 10837365 16455661 19351910 20823682 12691701 16105834 12490396 17537731 22345292 10228026 16453001 19278584
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
NFKB1 TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15723831 15041463 19392652 18990758
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
RELA NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18204072 17876798 24083678 15499023 25759022 23422506 12859951 7775482 11744993 22723832 23450368 11060311 12885753 18981184 9250151
SYK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21674813 21459462 19014652 12711606 24101387
TRAF6 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7862124 7739562 11087742 10195894 7796813 12514169 7878466 8657102 16493424 17965022
RELA NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 134.0 1.0 Omnipath 17145710 15657065 11801607 25609694 15226358 17003112 9057089 26496610 19219072 23850221 7831327 12927781 16683270 17301240 17561400 9566883 10391945 8887633 16209943 21719482 10066434 8657102 10581242 29734393 21988832 12419806 14743216 16105840 15671248 9751059 9990853 25759022 10498867 8246997 7878004 11020244 9426183 15845455 26476452 23563313 16951195 25520503 9694722 11287411 10329681 15799966 17612295 24457201 10085161 10837071 10969074 11571291 9573251 15214841 16846590 20065107 7479976 24248593 8887627 15145317 16493424 9135156 24634218 7479848 15024091 14636585 26463447 7862124 1340770 22081069 8139561 27923823 16970925 9738011 9865693 9572494 11231305 14685242 20797629 11313474 16226509 14690596 22022389 21217772 26186194 30213788 15371334 8978697 20980497 7739549 7628694
PRKCZ PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14576165
PRKCZ RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11684013 21515635 15210811 21131967 12881425 34230209 16189514 17183360 33864076 27466442
RELA TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15041463 19392652 21573233 15723831 9733516
SKIL SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12764135 23331499 21071413 22442258 11306568 16959829 10531062 12793438 17469184 15231748 11691834 12426322
SMAD3 TAGLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14654367 16876108 24464808 18245174 17981798 16224064 19344627
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TOP2A SUMO2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TOP2A SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TRAF2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TRAF2 TNFRSF1B â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TNFRSF1B TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8702708 10206649 16713569 8069916 7544915 18161752 14743216 9162022 15572357 18671942 9461607 8855313 11907088 8710854 11112773 15485837 9168896 8548810 7639698
TDP2 RBMS2 â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
TDP2 COX6B1 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
TDP2 SYT1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
TDP2 LGALS3 â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
TDP2 VAT1L â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
TDP2 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.37 1.36 PKG 28854368
TDP2 RAB25 â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
TDP2 ICAM1 â—¼   KO_UP_REGULATES ✅ + 1.45 1.45 PKG 28854368
TDP2 MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.67 1.66 PKG 28854368
TDP2 MT1G â—¼   KO_DOWN_REGULATES ✅ - -1.69 1.68 PKG 28854368
TDP2 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
TDP2 ASS1 â—¼   KO_UP_REGULATES ✅ + 1.72 1.72 PKG 28854368
TDP2 DND1 â—¼   KO_DOWN_REGULATES ✅ - -1.88 1.87 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
TDP2 TAGLN â—¼   KO_DOWN_REGULATES ✅ - -2.57 2.56 PKG 28854368
TDP2 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -2.81 2.8 PKG 28854368