Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
VAT1L HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XPC VAT1L â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
CK024 VAT1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HEP2 VAT1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VAT1L PIBF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VAT1L UFSP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
RECQL5 VAT1L â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
EXO1 VAT1L â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
TP53 VAT1L â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
FANCM VAT1L â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
TDP2 VAT1L â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
SETX VAT1L â—¼   KO_DOWN_REGULATES ✅ - -1.76 1.75 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
DDB2 VAT1L â—¼   KO_DOWN_REGULATES ✅ - -2.06 2.05 PKG 28854368
POLB VAT1L â—¼   KO_UP_REGULATES ✅ + 2.29 2.29 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368