Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15674334
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
TP53 SERPINB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TREX1 MT1H â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
TP53 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12011991 15578720 17700520 10692390 17204482
RECQL4 MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
DDB2 MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
TP53 MT1H â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
TDP2 MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.67 1.66 PKG 28854368
MUS81 MT1H â—¼   KO_UP_REGULATES ✅ + 1.72 1.72 PKG 28854368
SHPRH MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.89 1.88 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
SMARCAL1 MT1H â—¼   KO_UP_REGULATES ✅ + 2.19 2.19 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
SMARCAL1 SMARCAL1 â—¼   KO_DOWN_REGULATES ✅ - -7.33 7.32 PKG 28854368