Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
ENSG00000259040 TXNDC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PRDX4 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR4A1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RYBP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AURKA HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17604723
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
CANX RNF113A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
ESR2 TBXA2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17660955 16199482
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRN RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KDM2B PRDX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18838535
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   COLOCALIZATION 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
TBXA2R PRDX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17644091 5220101
RYBP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRDX4 GRP78 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32457219 33957083
GRP78 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 33957083
ATX1 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
AGR2 PRDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 PDIA6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
BMI1 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CFTR PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ESR1 CLIC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
EP300 PRDX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
ESR1 PRDX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
PRDX1 PRDX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
ESR1 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
RYBP FADD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11395500 16189514
ENSG00000259040 PRDX4 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ERP44 PRDX4 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
GRP78 APOB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19164805 12397072
CFTR GRP78 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833 17110338
CFTR PRDX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR CLIC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR PRDX2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
PRDX4 PRDX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 21988832 16189514 9388242
CUL3 PDIA6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
PRDX2 PRDX3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TERF2 H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 22157895 21824286
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PDIA6 PRDX4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRDX4 TXNDC5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
PRDX1 PRDX2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EP300 NR4A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082103 21988832 16713569 20438716
RYBP KDM2B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 34316702 26186194 27705803 23395003 28514442 22325352
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FADD TNFSF10 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
GRP78 PDIA6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24189400 22939629 33957083 30021884
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
DUSP23 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
PRDX4 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
INS P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25091901 31184304 21308844
MAP4K2 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NR4A1 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TNFSF10 FADD â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 10894160 5212774
KDM2B RYBP â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CANX RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PRDX4 RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AURKA FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21978935 26563258
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21486948 23892277
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21233487
PRKCZ FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 11739185
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
POLM PRDX4 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368