ACKR3
|
CXCL12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9618518
16107333
|
IKBKB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23332762
|
MAP2K1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15994315
15121878
|
SHC1
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7516469
5220322
|
LYN
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
LYN
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
LYN
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
CRKL
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
GNAI3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8327893
19703466
|
CCL21
|
CCR7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8383238
7851893
|
BMP10
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17068149
17311849
|
JAK2
|
CNTF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
VEGFA
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12810700
12215529
|
VEGFA
|
SHC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10749680
12214271
|
SOS1
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9544989
6547749
|
SHC1
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10704825
5212298
|
IL2RG
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
8643566
|
CNTFR
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
JAK2
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
CNTFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
JAK2
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
JAK2
|
EBI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
JAK2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
IL13RA1
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8609418
23331499
|
IL2RG
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8041779
24608040
|
TGFBR1
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
19114990
|
CHUK
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CHUK
|
IKBKB
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CSF2RB
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1465135
8294403
|
CSF2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1465135
8294403
|
VAV2
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
CD70
|
CD27
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17237405
19062317
|
VAV2
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8994827
9032261
|
CDC42
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11704645
14724572
|
CXCR4
|
CXCL14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23669361
8427967
|
CXCL14
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32239134
28360196
|
GRK5
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24632620
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
NFKB1
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17350185
|
NFKB1
|
AMH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15383177
|
CSF2RA
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1465135
8294403
|
GNAI1
|
GNG2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
8189321
21552208
|
GNAI1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15922020
19703466
|
GNAQ
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
ACVR2B
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
IL5
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1465135
8294403
|
IL3RA
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1465135
8294403
|
GRK2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10085131
|
CXCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22633458
15178708
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMP8B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
BMPR1B
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1B
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1A
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10712517
|
ACVR2B
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
ACVR2B
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMP8B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
CCL1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11470772
10910894
|
CCL18
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23951310
32103204
|
CCR3
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR6
|
CCL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9169459
12149255
|
BMP6
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
CNTFR
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21715184
10966616
|
CCR2
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CX3CR1
|
CX3CL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9024663
9390561
|
CCL25
|
CCR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10229797
10640743
|
ACVR1
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ACKR3
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
LYN
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
9573010
|
SHC1
|
SHC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CSF2
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11468284
9187659
|
RAC1
|
RAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CD70
|
ADCY6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAC2
|
RAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ACVRL1
|
BMP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
CXCR2
|
GNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
CXCR2
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
CXCR2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
11170396
|
SHC1
|
IL2RG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
8643566
|
CCR5
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11278738
11591716
|
JAK3
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10506573
|
CSF3
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16492764
10364174
|
CD27
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNA2
|
IFNA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BMPR2
|
BMP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11401330
10504300
|
PRLR
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9202403
10772872
20962278
|
CD70
|
CD27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7479974
8186199
9862673
9767422
21917027
15723067
8120384
33961781
26186194
8580829
|
CSF1R
|
SOS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10025673
7520523
|
IKBKB
|
NFKB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
11158290
|
LTA
|
LTBR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
SHC1
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
7516469
7650013
|
CRKL
|
SOS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9162067
26496610
33961781
32203420
23397142
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
LTA
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
CCR3
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8642344
10733106
|
BMP7
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8006002
18070108
16189514
|
CCR4
|
CCL22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9743322
9933589
9430724
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
CRK
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8035825
9837978
9461587
9617486
19380743
10464310
23397142
|
AKT1
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10869359
25241761
28628118
28205554
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
ACVR2B
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CSF2RB
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CCL5
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
BCAR1
|
PTK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CCR1
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8530354
7545673
9336350
|
CCR5
|
CCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9334377
10477718
9169459
11700073
9468473
|
CXCL9
|
CXCR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9660793
11259614
12782716
9625760
|
CCR3
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
10733106
8642344
7622448
9289016
|
CCR1
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
12270118
8530354
7545673
14637022
11116158
7622448
9115216
9289016
10910894
9336350
|
EDAR
|
EDA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11309369
11035039
|
GNAI1
|
GNAI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ACVR2B
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CNTF
|
CNTFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CSF2RB
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
BMPR2
|
BMP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7644468
7791754
|
IL2RG
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
11886175
10903799
8006584
20816854
|
CDC42
|
RAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31871319
9427749
|
CD4
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10816381
15660419
14592831
|
GDF5
|
BMPR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19229295
9525338
|
BMP4
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BMP2
|
BMPR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
BCAR1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BCAR1
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9498705
8810278
10753828
22974441
8978305
18835194
|
SHC1
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9824671
14557262
17001306
|
SHC1
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
8294403
10602027
|
CCR5
|
CD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10816381
30542158
15660419
|
CSF1R
|
IL34
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22483114
23478061
|
BMPR2
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7890683
28514442
7791754
|
BMPR2
|
BMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28126904
12045205
7673243
7644468
8702914
|
BMPR1A
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
JAK2
|
LEPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IKBKG
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
8209688
506093200
16126728
|
BCAR1
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9581808
9020138
|
CXCR1
|
CXCL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1840701
3260265
9164944
|
NFKB1
|
CXCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11559712
|
NFKB1
|
CXCL9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12403783
17274000
19157479
|
NFKB1
|
CCL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18270204
11342414
|
CCR7
|
CCL19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCR7
|
CCL19
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11698286
17035340
19759904
|
CCL16
|
CCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
SHC1
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
PTK2B
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
PTK2B
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10329689
16713569
|
JAK2
|
CTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11834704
7862649
7738033
|
JAK2
|
CSF2RB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2681215
1400495
1396555
|
JAK2
|
CSF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2681215
1400495
1396555
|
JAK2
|
CSF2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2681215
1400495
1396555
|
JAK2
|
IL3RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2681215
1400495
1396555
|
JAK2
|
IL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2681215
1400495
1396555
|
CSF3R
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
7775438
11812652
|
CSF2RA
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8977526
23331499
9028317
|
CXCR4
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17158356
10506573
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
PF4
|
CXCL8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15531763
12586630
|
AKT3
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19609947
|
PRKCB
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12070292
|
IL2RG
|
IL21R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11418623
11016959
12093291
|
IL15RA
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17709786
15265897
7641685
|
NFKB1
|
CCR7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19164127
11830455
22158872
|
CSF1R
|
CSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26235028
2408759
22483114
8355686
22153499
22902366
|
CSF1
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16492764
23331499
|
CSF1
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
CCR5
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12429730
15660419
18632580
|
NFKB1
|
CCL22
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12820969
17018379
|
NFKB1
|
LTA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2104232
19126379
18990758
|
PRKCB
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12070292
|
CSF3
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
GRK2
|
GNAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10567430
16339447
10727532
|
AKT2
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10869359
|
PRKCB
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1386920
17570479
12917261
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
PIK3CB
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
21653832
16456001
10068651
|
JAK3
|
IL21R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11418623
11016959
12093291
|
IL21R
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
12093291
|
AMHR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14746809
16446785
|
ACVR2A
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12682303
9032295
8612709
|
BMPR2
|
BMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10880444
10712517
25938661
7791754
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
CCR3
|
CCL11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8676064
10733106
9169459
9712872
9207005
8642344
25450766
8609214
23597562
|
CCL13
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10699158
23846739
|
CLCF1
|
CNTFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26858303
11285233
10966616
11294841
|
XCR1
|
XCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7875320
8849694
7602097
|
CCR10
|
CCL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
CCR10
|
CCL28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
XCR1
|
XCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7875320
8849694
7602097
|
BMPR1B
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
SHC1
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
IL34
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
24890514
|
CCL19
|
CCR7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
9153236
9507024
|
SHC1
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
7535773
9126968
|
JAK3
|
IL2RG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
7973658
16189514
27742835
7973659
|
AKT1
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
18191226
19122674
19262695
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
BCAR1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CD40
|
CD40LG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL15RA
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL15RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CSF3
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL13RA1
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
GNAI1
|
GNAI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
22939629
33961781
26186194
|
IL2RB
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
CCL20
|
CCR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
10488147
10498628
9169459
9223454
9294137
|
ACVR2A
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
CHUK
|
GRK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
FASLG
|
TNFRSF6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ACVR2A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CSH1
|
CSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
SHC1
|
SOS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
8631299
10570290
10025673
8235613
8626525
9544989
10675333
10783152
8950973
7559490
19380743
16371368
9344843
7520523
8621459
|
IKBKB
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CHUK
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
CNTF
|
CNTFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7810882
10812968
18775332
8627290
20584990
7539796
|
SOS1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25241761
31980649
8810325
17474147
8943292
33961781
19380743
32203420
|
BMPR1A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19804412
7261592
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CCL11
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CCR5
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
CSF1R
|
IL34
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
IKBKG
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219009
16938294
|
IKBKB
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.98
|
0.98
|
mint
|
8209688
16126728
506093200
|
GNAI1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
BMP2
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CRK
|
BCAR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
31980649
9581808
22974441
15673687
10208419
12615911
10464310
15492270
12799422
18835194
8631823
10747099
11278916
16413489
10753828
16267043
10329689
19380743
10085298
14657239
27669437
17038317
9920935
11369773
11839772
|
GNAI3
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
GNB1
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
BRAF
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GNAI1
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CXCL12
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23396314
20956518
24218476
16107333
22633458
20161793
|
CXCL11
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
29386406
29180449
27875312
24218476
22633458
16940167
20161793
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
CXCL12
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
24023874
10233851
10699158
11859124
22633458
18648536
18448868
8752280
30476826
12714578
16725153
9712844
8752281
9551924
21757744
19837984
25495026
26582643
16626895
|
CXCL12
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9660793
|
IKBKG
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
IKBKG
|
CHUK
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
NFKB1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CSF2
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
VEGFA
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
33.0
|
1.0
|
ACSN
|
10022831
11166270
11280761
11460167
11960372
12629515
13678960
14660645
15099563
15111329
15501236
15520864
15573129
16002046
16572188
17086423
17301840
18264787
19414323
21133840
21232017
21372296
22064427
22461508
23390297
24346288
24699077
24958845
26201938
8837607
9157999
9570538
9753319
|
NFKB1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
AKT1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20837477
20098747
17660512
|
IKBKG
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
150.0
|
1.0
|
Omnipath
|
17145710
16938294
20932476
35339487
18266324
16260493
27929056
25979343
19666608
26496610
12133833
12192055
9751060
21423167
19706536
15836773
17561400
22099304
23986494
19959994
15327770
25400026
24266532
18450452
12657630
20434986
11583588
20200955
20300203
21903422
22990857
14743216
20167598
20098747
16126728
19656241
25852190
16906147
10195894
17000764
18329793
16186825
16547522
16611882
18037881
10968790
16497931
25286246
18462684
18207244
16603398
17965022
17977820
24240172
17568778
15084594
16129692
23506214
16319058
23123196
18949366
15218526
22605335
20368414
10837071
19820708
10980203
23131831
17363973
15214841
25304104
16493424
15184390
15691841
11864612
15802604
17693255
21455180
11865184
20211142
11971985
16970925
24469399
24618592
12486103
11057907
24369075
19365808
18583959
27426725
12612076
19422324
10094049
23109003
21803029
12459277
21640763
16285893
18266467
12709429
15620648
17072322
19815509
15749833
|
IKBKG
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17145710
17485448
16938294
11865184
11877453
16970925
22435554
17244613
17568778
17363905
16818229
15084594
15485931
24369075
20300203
21217011
12799363
23180781
14743216
16319058
21703539
19666608
20098747
12612076
16126728
15218526
23430059
9751060
20138012
18716620
20368414
10837071
25355947
15836773
23109003
20531300
17702576
17363973
15214841
12459277
17561400
21640763
16285893
28462531
12709429
10968790
15199157
26192618
12133805
16497931
11864612
17693255
17072322
11340079
|
IKBKG
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
LYN
|
CSF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
LYN
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
LYN
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9581808
9020138
10428862
|
LYN
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23109003
7650013
7516469
10329689
|
LYN
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7636265
10672044
7722458
9973406
11823534
10329850
|
LYN
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18453587
23109003
12495636
17570479
11311138
7529876
10593973
|
TGFBR1
|
MAP2K6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11274345
12738796
14557817
15265520
15282297
16200688
16474430
17934056
18855897
20060931
20519943
21614932
22703233
23070005
24132110
24336330
24403530
|
TNFRSF1B
|
MAP2K6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
TNFRSF1B
|
MAP2K3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
LTA
|
TNFRSF1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8182064
9552007
2160731
7995952
1328224
8123048
1310388
|
CCL7
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
14991608
12381680
9115216
10699158
11994538
7545673
22633458
9336350
8530354
|
CCL7
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8642344
10733106
10699158
22633458
|
CCL7
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9276730
22633458
9115216
10699158
9346309
9195948
9312096
12554737
9336350
7759884
8530354
|
CCL7
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
10477718
16298345
10699158
22633458
10477710
|
CCL7
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
9364936
|
CCL7
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
9660793
|
CCL2
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
CCL2
|
CCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
TGFBR1
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
CSF1
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11306493
15749884
16713974
17404308
20547845
24669294
|
NFKB1
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10644332
22189654
20038977
11512674
8630731
12488502
12540607
11716760
8617886
12218154
14631383
16325549
10744656
10530453
11006087
16040075
10987310
16206198
9388261
10614622
16818736
10636866
10469356
17507908
12647268
16764699
25108845
20200316
15950427
20579762
11949945
|
CCL2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
10770925
10488147
10699158
22633458
9169459
11470772
28389721
9336350
8530354
15629146
11310855
9276730
20219869
9115216
9346309
9312096
9837883
10529171
15207250
9287323
12554737
7759884
|
CCL2
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9364936
10706668
|
CCL2
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8631787
7679328
76793288631787
9115216
10699158
|
CCL2
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8642344
|
CCL2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10477718
16298345
1629834510477710
|
CCL2
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17160712
16421945
|
CXCL8
|
CXCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL8
|
CXCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL2
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9260277
16189514
1379593
12964882
|
CXCL6
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8702798
10699158
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL5
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
9692902
12964882
9485196
|
PPBP
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702798
1427896
8195702
8137938
24335961
16189514
22633458
|
CXCL8
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
8702798
8137938
9195914
10699158
1840701
12628493
10188995
15946947
22262769
8550564
9553055
1379593
8662882
8245475
10368283
9485196
8940121
15282370
11350788
9725262
10206993
|
CXCL1
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9195914
10699158
16189514
1379593
12964882
|
CXCL3
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
129648828702798
8702798
16189514
12964882
|
CSF2
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
NFKB1
|
CXCL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8530498
7479086
15958549
10530453
16040075
11112786
|
CXCL1
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
7592830
8702798
9195914
10699158
12628493
22633458
10188995
12549928
8550564
28389721
16189514
1379593
8662882
9126332
10216072
24218476
8940121
|
CSH1
|
PRLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17145710
10966654
|
BMP7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9748228
7790373
12667445
|
BMP7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11282024
8006002
31619522
122976748006002
16189514
12297674
|
BMP7
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
106311828605097
8605097
10631182
|
BMP7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18342887
16446785
7791754
7644468
|
BMP7
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
16446785
|
BMP7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16189514
7791754
12297674
8605097
|
CXCL5
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
9692902
22633458
9485196
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
VEGFA
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
SHC1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRKL
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
SHC1
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
VEGFA
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
BCAR1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
CRKL
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
CCR5
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
15251452
|
CXCR4
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
ARRB1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
ARRB2
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
GNAI3
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
8327893
|
GNAI3
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
TGFBR1
|
CCL3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
NFKB1
|
CCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11716760
17707233
16982926
11342414
|
CCL3
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
11170631
10734056
10488147
10699158
7545673
10202040
22633458
10498628
9169459
9336350
10910894
8530354
23765404
9687537
9207005
20219869
9115216
9624164
10660125
7622448
12381680
|
CCL3
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8573157
|
CCL3
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
7594543
7622448
|
CCL3
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
11170631
16298345
10477718
23765404
15075201
9468473
20219869
9169459
11700073
10699158
9334377
9790730
22633458
12964882
|
CCL21
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11970971
10488147
9507024
10699158
16713569
22633458
22221265
9585422
|
CCL21
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26888559
11907075
|
CCL21
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10706668
23341447
16713569
22633458
|
BMP10
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17068149
|
BMP10
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15621726
16049014
|
BMP10
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30246251
30246252
27252362
31127068
|
BMP10
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15621726
31127068
16049014
|
CXCL9
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9660793
12782716
15761110
9625760
12750173
10699158
11259614
12884299
|
CXCL9
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
CCL4
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
7594543
12381680
10699158
7545673
10910894
8530354
|
CCL4
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7622448
|
CCL4
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10699158
9521068
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
CCL19
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
|
CCL19
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10706668
23341447
16189514
22633458
|
CCL19
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CCL19
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10512740
9507024
15546958
10699158
9153236
24218476
22633458
11342595
16904643
|
CCL22
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9933589
9430724
29637711
10699158
22633458
9743322
|
CCL17
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10498628
10488147
9169459
9430724
29637711
10699158
9169480
10540332
22633458
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
CNTF
|
CNTFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
23331499
10812968
18775332
20584990
7810882
8627290
8081242
7539796
10966616
|
CXCL8
|
CXCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL8
|
CXCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL6
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8702798
9485196
16189514
9692902
22633458
12964882
10593335
|
PPBP
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8702798
9126332
1427896
8195702
24335961
8550564
10699158
16189514
22633458
|
CXCL3
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
22633458
|
CXCL2
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8940121
8702798
9260277
8550564
10699158
16189514
1379593
22633458
10188995
12964882
|
CXCL8
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
7592830
8702798
22904195
9195914
10699158
7559482
12628493
23597562
10188995
15946947
8626516
8550564
9553055
1379593
8662882
19190236
8245475
9126332
10216072
1891716
9485196
8940121
15282370
9464567
11350788
11511101
9725262
10206993
|
CCL16
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11470772
22633458
10910894
|
CCL16
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
10910894
|
VEGFA
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
SHC1
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
VEGFA
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
NFKB1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18184402
17673602
16684540
15517885
12160329
15856023
18056465
20538607
17407600
20103608
|
SHC1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17540168
11278486
11804587
12670394
|
SHC1
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
CXCL8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11283723
11447289
11449354
11777939
12175651
12393695
12640133
15520864
15567848
15574420
16076871
16582911
16887996
17496910
17673906
19223473
19449109
26552706
8551221
|
IL2RB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8294403
8700888
8643566
10602027
16189514
24737791
|
IL4R
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11714803
10652211
|
PTK2B
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16713569
7544443
10749687
|
TGFBR1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
12767520
22710166
23331499
19010789
16474430
19920116
22943793
17934056
20519943
12809600
21900405
11133108
14557817
15548370
17673906
|
CSF2RB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10704825
8647804
10477722
|
JAK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9126968
7535773
|
SHC1
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
9544989
8631299
8621483
8950973
10891441
10783152
9278309
17673906
9344843
8294403
8021500
10025673
7520523
12955078
12577067
9199344
19531499
7760801
10570290
19380743
8235613
10675333
8114695
|
CRK
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
CRK
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
BCAR1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
9920935
11369773
11278916
15673687
8662907
9581808
8631823
8070403
10747099
12065577
10329689
16267043
10592173
10208419
17038317
18835194
20627867
16413489
10753828
8943292
9860979
11839772
14657239
12799422
19380743
15492270
10085298
12615911
|
CD40LG
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD40
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
NFKB1
|
CD40LG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11751888
11529914
21243522
11160303
|
CD40LG
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
1280226
1374165
19426221
7516405
11163401
7543281
12324477
10647992
17183360
|
JAK2
|
IL13RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
JAK2
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
JAK2
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
JAK2
|
CSF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
JAK2
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
IL2RG
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
JAK2
|
IL13RA1
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
JAK2
|
CSF2RB
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
JAK2
|
CSF3R
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
JAK2
|
CSF2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
JAK2
|
IL4R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
JAK2
|
CSF3R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11867689
14610620
18400509
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
JAK2
|
IL13RA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
CRLF2
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18988627
23331499
10872831
|
IL1B
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10198225
7528775
9038232
8943050
9454765
7594594
|
IL4R
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8609418
18852293
12223527
|
PRLR
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
9202403
21071413
17312100
18988627
20962278
11713228
10772872
|
IL3RA
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
15988755
17312100
15795318
|
LEPR
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17145710
23331499
30044226
17312100
8608603
18718905
12657512
21166956
9092791
|
JAK2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9670957
|
TGFBR1
|
CCL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
NFKB1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
12820969
11413310
11478739
12122011
17065335
17510282
11700023
15144466
19786024
16707500
21189258
12388374
15972972
9120310
11389171
12050170
11259372
|
CCL5
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CCL5
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10734056
7622448
8642344
22633458
10733106
10699158
9289016
|
CCL5
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10734056
7622448
14637022
22633458
9115216
9624164
10699158
11116158
12270118
7545673
9289016
9336350
10910894
8530354
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
CCL26
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
10699158
16339911
22633458
|
CCL26
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
12689946
22633458
|
CCL26
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
15039444
|
CCL26
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
29637711
15039444
|
CCL26
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
20974991
29637711
|
GDF9
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14684852
14514671
27252362
|
TGFBR1
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
14580334
18333754
|
NFKB1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
9510190
12058956
11973337
18786178
17045242
15289496
16701870
19376732
19837667
9698090
17276517
11512674
19786024
20038977
10202011
15057743
15517885
12643600
11342414
7876168
15350531
18034886
11716760
11564889
11864912
12218154
12707271
10969814
12748173
14631383
16325549
17586662
18996370
19732956
17041011
10530453
18281166
12716652
16418726
12485925
16004996
9388261
8878392
17917246
10975857
10745031
10928981
16553947
16818736
14670967
18435575
12038622
15958549
17040605
8413215
21255844
22340043
1401924
9452482
16764699
11297551
15950427
15387324
15879558
16105834
11953364
15688424
18074095
8413306
11096450
16803583
10506755
11120852
10477716
|
NFKB1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14563113
12655294
15160330
16770006
10671224
|
FASLG
|
TNFRSF6B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
14697332
9872321
11239407
10318773
11994433
|
CHUK
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
AKT2
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19609947
12048203
10485710
|
AKT1
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
15710601
12048203
25241761
19442713
11278366
10485711
15800029
19609947
17570479
17660512
18515365
19088076
10485710
|
CHUK
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
9346484
24911653
20932476
28514442
11971985
16970925
12210728
9346485
17965022
16713569
12486103
9891086
15456791
11057907
20434986
16129692
16260493
21903422
21724995
16286467
14743216
16319058
18949366
10779355
25748427
25852190
12244103
11585904
9751060
15218526
10094049
10837071
9914500
21575199
9721103
25241761
10195894
9689078
15214841
21784860
17561400
21640763
16285893
10733566
16186825
16493424
10022904
12709429
12351658
10968790
12547194
15691841
15620648
15327770
11864612
11460167
14636585
17693255
17072322
9346241
|
CHUK
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
12482991
19442713
14743216
15494311
11976329
15489227
16382138
16713569
10022904
10469655
27554194
11158290
11297557
|
IL2RG
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4R
|
IL13RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
IL2RG
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4R
|
IL13RA1
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
1825141
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
2965306
7512720
7521688
7543512
9535722
9834059
|
CSF2
|
IL4R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
IL13RA1
|
IL4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
12704343
16682236
18243101
8910586
|
IL4R
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
17312100
12207328
7538655
|
IL4R
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17145710
11815609
12704343
23331499
18243101
8266076
8266078
7918378
|
IL2RG
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
IL2RG
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
IL2RB
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
8568232
15265897
7514277
10903799
11886175
8026467
15933202
7681595
15178252
1545122
8260650
16189514
11851401
8006584
|
IL2RG
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
23331499
7973658
7973659
18445337
10856136
16189514
10629052
15621723
7973657
|
IL2RG
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
8568232
15265897
7514277
10903799
11886175
8026467
15933202
7681595
15178252
1545122
8260650
16189514
11851401
8006584
|
CSF2
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2
|
CSF2RB
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3RA
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL5
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
1833065
7957082
1495999
11748263
|
CSF2
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
1702217
2645577
18692472
8278375
2828352
7957082
|
IL2RB
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RB
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
JAK3
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
7693677
16189514
10825200
7973659
9553136
7973657
|
CXCL10
|
CXCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
CXCL10
|
CXCR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
NFKB1
|
CXCL10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20164184
16253303
17274000
20579762
16982926
19342664
10756005
16818736
19929594
19479051
21249144
24701034
|
CXCL10
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
CXCL10
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9660793
12571234
10233762
9625760
15761110
12750173
10699158
9064356
16189514
12884299
|
CSF2
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
NFKB1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9190901
11418664
12760745
8135780
8934574
14741709
18285351
10608823
|
CSF2
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
16720384
11091218
11468284
7691413
16492764
9187659
|
CSF2
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
10753826
8910448
11777960
27396825
12393492
19833085
10572088
22323450
23331499
22869907
9211889
24030977
11306493
11867689
9187659
11015446
1702217
2645577
20406969
23046136
20805416
2828352
7957082
18551128
26192618
18692472
21765015
24091328
27216177
2555171
14610620
12811837
|
CSF1
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
NFKB1
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18566389
10919279
11949945
7583532
|
CSF1
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7883784
8355686
1702217
22483114
22902366
2408759
26235028
22153499
24890514
26095744
|
RAC1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
VAV2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8990121
32203420
11790798
10592173
10982832
16397238
|
RAC1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17496910
18000759
15574420
19151919
11777939
18855897
21614932
12738796
11274345
12040186
19568798
14585353
|
RAC1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
16697215
20398329
17461779
18372248
20338997
15808505
20138985
20214616
21474067
19568798
15169778
19720745
18925875
10949026
11715018
19143635
12393431
18636226
10617634
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
CD40
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD70
|
CD27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
8120384
21917027
26697006
7479974
9862673
8580829
12324477
8186199
9767422
15723067
|
VAV2
|
CDC42
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10934226
11080163
11262396
12094222
14623913
15365099
15886116
9822605
|
CD4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10816381
29637711
|
NFKB1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8413223
17707233
11058167
12686724
16433741
18285351
8021507
9878621
14960579
10963848
9058643
15543947
20696864
8679226
11035101
15972680
20336759
18772363
10080875
17082635
|
GRK6
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
30936203
25355818
20048153
24309376
19116316
28328745
24489825
|
GRK3
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11668182
16189514
|
CXCR4
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23109003
11406370
12495636
16189514
17169327
10506573
|
CXCR4
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
10506573
|
AKT1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
19651622
20058876
14688280
11510412
25241761
20230923
20068231
18452278
11410590
17570479
10869359
18669648
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15184909
25241761
22689577
15856005
10485711
17660512
|
IKBKB
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
NFKB1
|
CXCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17363596
28266569
15132979
15722553
|
NFKB1
|
EBI3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9733827
15728491
24214980
|
NFKB1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17513725
11313274
19164127
11027342
17031478
9733827
|
NFKB1
|
CCL11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16604092
11076795
15972682
10586089
14660485
|
IKBKB
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
57.0
|
1.0
|
Omnipath
|
31598684
11976329
16713569
10469655
29485707
26999213
12842894
10835356
27187478
27402796
18782567
27554194
12482991
25241761
10022904
15199157
19519322
15489227
19250910
15212693
11158290
11297557
|
JAK3
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21071413
23331499
9512511
|
CSF3
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
10537111
10364174
15676205
16492764
|
GNB1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
GNB1
|
GNG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GNG2
|
GNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
ARRB2
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
ARRB1
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
CCR5
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
15251452
|
GNAI1
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
GNAI1
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9748257
23109003
15539636
7935349
16460834
11376933
|
BRAF
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
67.0
|
1.0
|
Omnipath
|
20212043
7706312
25437913
9560161
7936666
14970219
18567582
18332145
8413257
23331499
15342917
21071413
7731720
7873542
26496610
10976102
18988627
17667937
16255777
8131746
16888650
15485920
8394352
15175348
15466476
19541618
25600339
25155755
17563371
16810323
8157000
17979178
18039929
94178255
23934108
7835430
7624324
24746704
16135787
7935374
8039496
8621729
|
MAP2K1
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
28169830
11226259
|
AKT3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10869359
18451171
11293329
19493313
|
CCL13
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10477718
9790730
|
CCL3L1
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
11170631
10364178
10477718
16298345
11734558
11449371
11700073
9790730
22633458
12964882
|
GRK3
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
25923671
12403770
12065593
10085131
11782464
18753410
21148810
|
CCL8
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
22633458
12964882
|
CCL14
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16298345
20483925
22633458
11085751
12964882
|
CCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
11264152
22633458
12964882
|
CCR5
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
11406370
12495636
17169327
|
IL34
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18467591
22483114
30205037
22729249
23478061
29796177
31616414
24890514
26095744
|
AMH
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14656470
|
BMPR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
7791754
7890683
|
BMP6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12297674
|
BMP2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8006002
28977600
|
BMP4
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7811286
8702914
11282024
8006002
|
GDF5
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702914
15890363
9525338
11282024
16127465
15569154
19229295
|
BMPR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
18756288
10712517
7791754
|
AMHR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16446785
14746809
11420127
|
BMP6
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11401330
10504300
|
BMP2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7811286
12700180
9872992
10712517
15064755
19229295
|
GDF9
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
BMP15
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
12044914
12419820
1204491412419820
|
GDF9
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
GDF5
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8702914
|
GDF7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17483092
10880444
21702718
17295905
25938661
20959140
|
BMP6
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504300
|
BMP4
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8702914
23331499
21071413
16446785
12045205
8006002
7673243
7644468
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
BMP2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
20385559
16446785
28977600
15064755
18988627
17295905
|
BMP2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
51.0
|
1.0
|
Omnipath
|
17145710
17483092
10880444
10712517
26330344
21054789
16672363
10881198
11263668
20860622
15064755
18937504
25938661
15621726
12700180
10692589
19804412
|
BMP2
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10880440
23331499
11263668
23180781
18342887
16446785
10880444
10712517
7791754
17295905
25938661
24337809
|
GDF5
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
8702914
16446785
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
GDF9
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12135884
10712517
|
BMP5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11580864
16189514
|
BMPR2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18756288
7791754
10712517
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
GDF6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9525338
160490149525338
16049014
|
GDF7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
21543859
9525338
11282024
16127465
19229295
|
GDF5
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8702914
23331499
9525338
23180781
18342887
16446785
19229295
87029149525338
|
LTA
|
LTBR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7995952
8171323
|
CCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9660793
96607939660793
22633458
|
CCL11
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
15207250
9276730
9115216
9195948
11264152
22633458
12554737
12149192
|
CCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10488147
10699158
22633458
12218106
23597562
25450766
12149192
16102831
8642344
9169459
9005985
16339911
8676064
9276730
9207005
24702154
9712872
10733106
10706854
12761559
8609214
10854442
|
EDA
|
EDAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
11039935
18304980
10484778
11309369
11035039
12084975
|
CCL15
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL8
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10699158
22633458
9115216
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CCL3L1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11170631
11449371
12381680
9115216
9624164
7545673
10202040
10660125
22633458
8530354
|
CCL14
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9687537
9548457
15905581
12381680
20483925
9346309
9405404
24218476
22633458
11085751
|
CCL8
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10699158
9005985
|
CCL28
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
22633458
12964882
|
CXCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
15178708
|
CCL3L1
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11449371
7594543
22633458
|
CCL15
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL13
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9276730
10733106
9005985
10699158
16339911
22633458
12149192
|
CCL14
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9548457
9346309
11085751
|
CCL24
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
22633458
10733106
10699158
16339911
12218106
|
CCL18
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10640766
29637711
23999500
24218476
22633458
23951310
|
BMP15
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15621726
23331499
12419820
16446785
|
BMP6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
11401330
10504300
|
GDF7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
9525338
16446785
18988627
160490149525338
16049014
|
GDF9
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1213588412135880
12135884
|
CCL20
|
CCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10498628
9223454
10488147
9169459
9294137
10699158
12081481
24218476
22633458
12964882
|
CCL20
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9660793
|
CLCF1
|
CNTFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11294841
11285233
10966616
|
PF4
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21655676
12782716
10699158
|
CCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CXCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11554781
16189514
22633458
|
CXCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
15273303
9625760
15761110
12750173
10699158
16189514
11259614
12884299
|
AMH
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8889695
23331499
8119126
16446785
18988627
79972308889695
7997230
|
XCL1
|
XCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
25497737
10699158
10518929
19556286
22633458
11446740
9632725
|
CCL8
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115216
10699158
9195948
22633458
12554737
12149192
|
CCL24
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
|
CCL13
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9276730
10699158
24890717
9195948
22633458
12554737
12149192
|
CCL27
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10781587
11821900
12718728
10725697
22633458
|
CCL28
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
10781587
22633458
|
CXCL13
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CCL25
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CX3CL1
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9390561
10488147
14607932
10699158
28389721
11432858
16189514
22633458
9931005
|
CCL17
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12832759
10699158
9521068
10910894
|
CCL8
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
26740381
9405404
10734104
|
CXCL2
|
XCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10518929
10679309
|
CCL13
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26740381
16189514
9405404
10734104
|
CCL25
|
ACKR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10706668
23341447
22633458
|
CCL1
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
12967681
16221874
9207005
12645948
9211859
11470772
10699158
11154210
9469461
10419462
10910894
|
CCL25
|
CCR9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10498628
10699158
11159507
22633458
10229797
|
XCL2
|
XCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
25497737
10699158
19556286
22633458
9632725
|
CCL18
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
23999500
|