Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CXCL8 GNG2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CXCL8 GNB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CXCL8 GNAI1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CXCR2 GNG2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCL20 GNG2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GNAI1 GNG2 â—¼   PROXIMITY 2.0 0.8 intact 8189321 21552208
CCR2 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
CCR3 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
ETS1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22869003 20428211
CCR6 CCL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9169459 12149255
CCL20 GNB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCL21 CCR7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8383238 7851893
CCL25 CCR9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10229797 10640743
CXCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22633458 15178708
GLI1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647328
CXCR4 CXCL14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23669361 8427967
CXCL14 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32239134 28360196
USF2 CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10229837
USF1 CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10229837
GNAO1 CXCR5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15251452 5217114
CXCR5 GNAI2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15251452 5217114
GNB1 GNAI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7102203 16782902
USF1 PF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15187018
USF2 PF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15187018
CXCR2 GNAI1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CXCR2 GNB1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CXCR1 GNAI2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8903513 16189514 8662698
CCR4 CCL5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12270118 8573157
GNAI1 GNAI2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CCL5 CCR3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CCR1 CCL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9336350 9115216 9289016 12270118 11449371 10910894 7545673 7622448 11116158 8530354 14637022
CCR3 CCL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8642344 9289016 11449371 7622448 10733106
CXCL9 CXCR3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12782716 9625760 11259614 9660793
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GNAI2 GNG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
GNAI2 CXCR5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15251452 25241761 23773523
USF1 USF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PROC PROCR â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PF4 CXCL8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15531763 12586630
CCR3 CCL11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8642344 8676064 8609214 25450766 9712872 10733106 23597562 9207005 9169459
CCL13 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10699158 23846739
CCR10 CCL28 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10781587 10725696 10725697
CCR5 CCL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9289016 11449371 10488147 8663314 11116158 10477718 9334377 9207005 14637022
GATA1 CCR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22217447 21041734
CCR5 CXCR4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12429730 18632580 15660419
CXCR1 CXCL6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1840701 3260265 9164944
ETS1 CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21741415 16840440
USF1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8900159 21050451
USF2 USF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15014447 21653943 19303849 17353931 9053857 26496610 16943425 8576131 28514442 18817855 17846119
XCR1 XCL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7875320 8849694 7602097
XCR1 XCL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7875320 8849694 7602097
CCL20 CCR6 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 10498628 9294137 9223454 10488147 9169459
FGF2 FGFR2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CCL5 CCR5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CCL11 CCR3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GNAI1 GNG2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
GNAI2 GNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
GNAI3 GNB1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GNAI1 GNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNG2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CXCL8 CXCR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555778 18633355 18980965 21328342 21847358 24406209 25922287 26201938 26548401 27557510
CXCL8 CXCR2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 21328342 21847358 23869868 24406209 25922287 26201938 27557510
CXCL8 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 8702798 8137938 9195914 10699158 1840701 12628493 10188995 15946947 22262769 8550564 9553055 1379593 8662882 8245475 10368283 9485196 8940121 15282370 11350788 9725262 10206993
CXCL8 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 7592830 8702798 22904195 9195914 10699158 7559482 12628493 23597562 10188995 15946947 8626516 8550564 9553055 1379593 8662882 19190236 8245475 9126332 10216072 1891716 9485196 8940121 15282370 9464567 11350788 11511101 9725262 10206993
GNB1 GNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNG2 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
CCL11 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 15207250 9276730 9115216 9195948 11264152 22633458 12554737 12149192
CCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9660793 96607939660793 22633458
CCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10477718 9468473 10699158 9790730 11264152 22633458 12964882
CCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 10488147 10699158 22633458 12218106 23597562 25450766 12149192 16102831 8642344 9169459 9005985 16339911 8676064 9276730 9207005 24702154 9712872 10733106 10706854 12761559 8609214 10854442
CCL13 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL13 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9276730 10733106 9005985 10699158 16339911 22633458 12149192
CCL13 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10477718 9790730
CCL13 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9276730 10699158 24890717 9195948 22633458 12554737 12149192
CCL17 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10498628 10488147 9169459 9430724 29637711 10699158 9169480 10540332 22633458
CCL17 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12832759 10699158 9521068 10910894
CCL2 CCR2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10623817 15032599 17681149 19915063 23527025 23567181 23943801 24531940 27216177
CSF1 CCL2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11306493 15749884 16713974 17404308 20547845 24669294
CCL2 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8631787 7679328 76793288631787 9115216 10699158
CCL2 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9364936 10706668
CCL2 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8642344
CCL2 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10477718 16298345 1629834510477710
CCL2 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 10770925 10488147 10699158 22633458 9169459 11470772 28389721 9336350 8530354 15629146 11310855 9276730 20219869 9115216 9346309 9312096 9837883 10529171 15207250 9287323 12554737 7759884
CCL2 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17160712 16421945
CCL20 CCR6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10498628 9223454 10488147 9169459 9294137 10699158 12081481 24218476 22633458 12964882
CCL20 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9660793
CCL21 CCR7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11970971 10488147 9507024 10699158 16713569 22633458 22221265 9585422
CCL21 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26888559 11907075
CCL25 CCR9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10498628 10699158 11159507 22633458 10229797
CCL25 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10706668
CCL26 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15207250 12689946 22633458
CCL26 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 29637711 15039444
CCL26 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22633458 15039444
CCL26 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16102831 10488147 15207250 10699158 16339911 22633458
CCL26 CX3CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 20974991 29637711
CCL28 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 10781587 22633458
CCL28 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 22633458 12964882
CCL5 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 16298345 10488147 28381538 10699158 22633458 9289016 12213786 8663314 11449371 10318947 12964882 25923671 9207005 23480650 11116158 10477718 14637022 9334377 9790730
CCL5 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10734056 7622448 8642344 22633458 10733106 10699158 9289016
CCL5 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL5 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10734056 7622448 14637022 22633458 9115216 9624164 10699158 11116158 12270118 7545673 9289016 9336350 10910894 8530354
CCL5 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8573157 12270118
CXCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458 15178708
CXCL9 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
CXCL10 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
CCR5 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 15251452
CCR5 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 15251452
CCR5 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 15251452
CXCL10 CXCR3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 18514095 18922917 22798340 23567181
CXCL10 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 9660793 12571234 10233762 9625760 15761110 12750173 10699158 9064356 16189514 12884299
CXCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 15273303 9625760 15761110 12750173 10699158 16189514 11259614 12884299
CXCL12 CXCR4 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCL12 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24023874 10233851 10699158 11859124 22633458 18648536 18448868 8752280 30476826 12714578 16725153 9712844 8752281 9551924 21757744 19837984 25495026 26582643 16626895
CXCL12 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9660793
CXCL2 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8702798 9260277 16189514 1379593 12964882
CXCL2 XCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10518929 10679309
CXCL2 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8940121 8702798 9260277 8550564 10699158 16189514 1379593 22633458 10188995 12964882
CXCL6 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8702798 10699158 9485196 16189514 9692902 22633458 12964882 10593335
CXCL6 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8702798 9485196 16189514 9692902 22633458 12964882 10593335
CXCL9 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9660793 12782716 15761110 9625760 12750173 10699158 11259614 12884299
PF4 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21655676 12782716 10699158
CXCR4 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520 10506573
CXCR4 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
CXCR4 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
CXCR5 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 23773523 15251452
ETS1 PF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14673175 12609849 9874259 21931859 23848403 12732210
FGF2 FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 23331499 18332103 26267536 7687739 16597617 25772309 10830168 11390973 10950949 11121055 17981115 8663044
PF4 FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9558385
GATA1 PF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16141689 12609849 9874259 8288642 12732210
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
GATA3 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17717199 20399120 11970994 21507199 20193034 23232398 20636338 21632975 8228802 19648923 15251440 16520391
GATA3 PF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26227022 19559773
PF4 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1198621511986210 11986215
PF4 PROCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9395524
PF4 THBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 93955249395524 9395524
PROC PROCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7929370 11099506 10681521 16189514
PROC THBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12588872 11106601
USF2 USF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14669984 12857727 11075816 19416648
XCL1 XCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25497737 10699158 10518929 19556286 22633458 11446740 9632725
XCL2 XCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25497737 10699158 19556286 22633458 9632725