Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
STAT6 IGHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659391 9440542
CCNA1 CDKN1A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
YKT6 GOSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
H3C2 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KMT2E H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
E2F1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12629508
H4C6 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KAT2B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880483
DBH H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3C14 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
CREBBP H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CUX1 SI â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12101240 20945532
CUX1 ERVK-11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18347061 12665598
ABL1 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 CDH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
JUN ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
CUX1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14612449 22422878
AKT1 SP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21619873 21777568
AKT1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15461588 17570479
STAT5A BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695224 14500638
TCF7L2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17404573 23671559
RUNX2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17517365 23073173
STAT5B BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16741510 18793823
E2F4 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11559537 18319725
STX5 BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15215310 12388752
BIN1 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CA12 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
CCNB1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
STAT5B CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11160217 12586844
MAX CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11511535 10508165
CUX1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12374738 18085478
SELE CD44 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906074106 19889975
CD44 SELE â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7509040 21659548
TLX1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23628015 24548444
STAT5A CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16670309 23313770
HLA-B CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9331948 10809759
PAX6 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19666824
CDK1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
CDK1 DCTN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23455152
HRAS CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUX1 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12619038 12732645
SKP2 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16376880 5218183
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
HNF4A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17885207
SRF CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20068148 16819512
STAT5A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003515 21038417
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
SOX4 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810147106 19234109
CREBBP GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
STAT6 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15145939 10373589
JUN CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8375573 8380380
RECQL5 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ELAC2 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KRT8 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
E2F1 CUX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347061
CUX1 HIF1AN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17682059
CUX1 VEGFC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934313 19724686
CUX1 FTO â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23341774
CUX1 DAXX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21672609 22209758
CUX1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10545217 12794834
CUX1 OCLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20224295 19635798
CUX1 SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20224295 19635798
CUX1 RB1 â—¼   COLOCALIZATION 2.0 0.8 intact 12891711 5216580
JUN CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11278771 16729332
USP7 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6799761 18566590
E2F4 DHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
E2F1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20976175
E2F1 PTTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19837943
E2F4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
IKBKG FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FLNA TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FLNA IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
GATA2 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15739164 21454593
MYB HBG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16631597 21092141
HNF4A TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
VIM IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT5B IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421786 18820682
TCF7L2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
JUN SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9103451 9317150
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
KLF4 SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22203039 22937066
KLF4 SELE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24470523 17209004
KLF4 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16169848 20946687
VIM KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
MAX THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20876797 10871348
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
MYOD1 NEU1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16216242 14597183
RB1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21902831 8381715
NGF TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
NGFR TRAF6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16252010 16630834
TCF7L2 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849547 11935128
PAX6 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23622063 15558475
STAT5A PI3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11756417 14660677
SOX9 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605170103 17142326
SKP2 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26778333 26091038
SOX9 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306868 20593410
SNAI2 SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21645238 19756381
SOX4 TCF7L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17218525 17875931
SOX4 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17875931
VIM TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDK1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14681455 8565853 16009130 1628647 7799941
PNN SON â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RAB8B RAB13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SATB1 KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22328728 16630892
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
CUL1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 9663463
SKP2 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19270694 23911321 19270695 21358672
GOSR1 BET1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11927603 12388752
BMI1 NCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CCND2 RB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK2 E2F4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 33961781
GSTK1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TEAD1 JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 26258633
LHX3 SSBP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 35140242
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
RECQL5 CAV1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RAB8B RAB8A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26824392
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AGTR1 CAV1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EHMT2 CHD4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28486105 26028330 32744500
KIF23 ECT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19468300 31586073 22750944
SSBP3 LHX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 35140242 30833792
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
CHD4 SMARCA4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ABL1 RB1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GOSR1 YKT6 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AKT1 SKP2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
TRAF6 USP7 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BET1 YKT6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 33961781
CCNB1 CDK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 11113184
SOX2 CDK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
SOX5 SOX6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 9755172 33961781
CCNA1 SKP2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BET1L STX5 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
BET1 STX5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
FOXL1 SATB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
CREBBP STAT6 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NGFR NTRK1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL1 CDK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 21145461 26186194 9636170 28514442
KAT2B E2F1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 24112038 19188449 15123636 24502362 23001041
CREBBP KLF4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK7 E2F1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NGFR TRAF6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RAB40B RAB40C â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAB40A RAB40AL â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
E2F1 SKP2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RAB10 RAB8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 17353931
CUL1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16209941 33422522 26496610 21145461
CUL1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11245432 10559858
CCNA1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16774918 10022926
GOSR1 BET1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 11927603 33961781
RACGAP1 ECT2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 18201571 6166552
CCNA2 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
NTRK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10679771 10708759
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
E2F1 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11245432 7969176 8458319 1530885 9199321
CDK7 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 25852190 16191191 10393546 15282296 23064645 11113184 8647086 8692842 7629134 16327805 15530371
KAT2B IRF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10022868 11304541
RUNX2 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
MEN1 PSIP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22327296 18598942 23508102
SRF TEAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11136726 12061776
CCNA2 E2F1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDKN1A SKP2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK1 RB1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CCNB1 CDKN1A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAC3 ARHGDIB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SATB1 HBG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10595394 8049444 15618465
MYB CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10590070
KAT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34811519 16096646
MYOD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10973962 16901893 21689744
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
E2F1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11559537 18319725 11704823
HNF4A BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19463978 24291646 8055923
E2F1 BIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19629135 18348166
E2F1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23796898 17360938 16582100
CA12 DAXX â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SKP2 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 33989513 9858587 33422522 24632684 15355997 7553852 26496610 16209941 27720894 31181401 26186194 10559858 28514442 18604603
E2F1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 7969176 8458319 9724724 12501191
E2F4 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213 10766737 18319725
SKP2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9858587 15355997 33989513
CCNA2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9858587 15355997 33989513
MYB CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17242210
E2F4 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213
CCND2 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CD44 ICAM1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22566907 23620508 23886063
TCF7L2 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18483247 12782598 10027409
SKP2 CDK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 23455922 26496610 22770219 23602568 7553852 9636170 9858587 15355997 25852190 10386600 16979657 28514442 16189514 18604603 33422522 19686743 19270695 26186194 10559858
VIM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A NGFR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
SOX9 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19273910 20651055 11514554
CUX1 ECT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21886810 19015243
CUX1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23951412 16275928 10900073
CUX1 RACGAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21886810 19015243
CUX1 PI3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10753867 10229863 11689575
CUX1 KIF23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19015243
CUX1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
CUX1 PSIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22019592 23138933 22615874
CUX1 NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7556925 12619038 10900073
CUX1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16144552 10229863 10868937
E2F1 DHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 8441401 18319725
SKP2 E2F1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17471231 12097298 23868976 27720894 10559858 16170383
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18347061 7929342
E2F1 ECT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21886810 19015243
E2F1 KIF23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19015243
E2F1 RACGAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21886810 19015243
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15014447 11491305
E2F1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10567569 8137237 18319725
E2F4 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 16738312
E2F4 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15574595 18319725 16135806
HNF4A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317687 11741883 16479620
HNF4A VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568083 12750294 19671543
STAT5B IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15528362 12759422
KAT2B IRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022868 11304541
JUN NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15870692
STAT6 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22378047 25934862
TRAF6 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18093978
STAT6 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24459328 16189417 10882409
SMARCA4 TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
TCF7L2 SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20128911 19443654
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
CCNA2 SKP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
KIF23 RACGAP1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
E2F4 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
STX5 YKT6 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CDK1 CDKN1A â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CDK2 SKP2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ECT2 RACGAP1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CD40 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CDK2 CDK7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDKN1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CCNA1 CDKN1A â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CDK2 RB1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CUX1 RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
GOSR1 STX5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CCNE2 CDKN1A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
CCNE2 CDK2 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RB1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5219804 17380128
NGF NTRK1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SATB1 CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10800076 18722016 11937547 9218488
CCNE2 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CDK7 CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7533895 19847258 17386261 17884153 19667075 15703371 11959850 12648680 11900249 16697054 19809470
CDKN1A CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12383116 25241761 8756624 29997244 16982699 7478582 10022926 32814053 15232106 16009130 16189514
CCNA1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17660363 15840440 16135794 18590585 7575488 17303408 9736735 15133492 15558010 15123636 9556498 10022926 16213134 11980909 16123593 11739724 15279786
CCNA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7575488 18590585 17303408 10022926 16189514 17660363 15279786
GOLIM4 YKT6 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
YKT6 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
YKT6 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
E2F4 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799066
NTRK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10708759 10679771
CDK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19651622 17081983 2183353 18691976 18452278 18669648
ABL1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19818398 18619508 10637231 20841568 14757045 15302935
ABL1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24836440 8940193 20841568
ABL1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12415271 21212806 26998525 20841568
ABL1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 8242749 7828850 16158058 9071815 20841568
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
AKT1 GATA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27053161 15837948
AKT1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23807222 28446188 22733130 19270695 20160512 19549334 21963805
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
NTRK1 ARHGAP32 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12446789 25921289
E2F1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17404573 11559537 12679318
MYB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22101269 23675407 20237898 17823980 20659323 10692454 9096387 11675351 12384144 16088151 9823328
CREBBP BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9829964 10753867 17565603 15337521 10454566
CDK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24097825 24677263 23638364 19917720 27231850 11774038 11326318 10766756
GOLGA5 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
CUX1 BET1L â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
SP7 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22396760 21597276 18703512 22110141 22807088 21820092 17206379 24025680 11792318
JUN BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9257196 2124710 15831452 17308994
SNAI2 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CAV1 TGFBR2 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
E2F4 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 17121828 21311680 15448153
JUN CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9486962 23385061 15574764 17182846 15737994 21069729 9511728 20531301 21029732
E2F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7623816 11264255 9178900 20580656 14681231 10594784 24335704
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDKN1A CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23443559 26186194 21308745 9660939 8756624 15890360 9380407 8242751 8662825 12947099 9632134 17679094 26496610
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CCNA2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 12501191 16213134 11980909 16123593
E2F4 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 15855772 22508987
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
E2F1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15510213 7575488 18590585 17303408 18319725 17660363 15279786
RB1 CCND2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
STAT5A CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11160217 12586844 14660677 15509806 22723377
MAX CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
TCF7L2 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
JUN CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
CCND2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 16326706 9190208 7575488 9003781 10385618 9736735 7736585 19075565 18590585 20068082 9425340 8449399 18786381 17660363 19651622 11254678 8343202 10778858
CCND2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNE2 SKP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
SKP2 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CDKN1A CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 23443559 26186194 28514442 9840927 9840943 15232106 26496610 24358021
CCNE2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7575488 18590585 10207050 9315635 17303408 19638577 17660363 12006580 11420722 15279786
CDH2 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK1 RB1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
CDK1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
E2F4 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 17671431 11799067 11032828 17121828 17531812
E2F1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 7623816 14618416 12760745 11799067 8137237 12629169 17108174
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDKN1A CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9467962 26186194 21308745 15340381 23602568 23543736 24218572 17679094 15077146 26496610 12973835
E2F4 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15510213 16135806
CDK1 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17145710 12372621 25482410 18691976 25218637 23985307 15688006 9988268
CDK1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 17303408 19690332 15084261 19413330 19664995 15279786 7575488 21249227 92097548 20068231 18669648 18590585 1756735 17660363 19651622 20058876 18220336 10542199 19664994
CDK1 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 97207326 17570479 11788583 9054461 9524113
CDK1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20513426 26432751 28409123 27680387 28858266 26108642
CDK1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 17014844 10082583 10764802 9710583 14749395
CDK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21189248 16170345 22172673 22898780 18669648 16247472
CDK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 19007248 16565220 17081983 22120848 18767875 9168797 19690332 27603133 15766329 12761892 19413330 21465480 19664995 16260496 19415658 25960391 18578522 20068231 15713670 17570479 24073199 18491316 18669648 18691976 17287340 15345747 20068230 19651622 20058876 19691289 17924679 16542212 19369195 25184044 18707149 7983050 19584300 16964243 21422740 18212344
CDK1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407259
CDK1 PTTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17303408 18767875 19664995 15279786 15302935 7575488 21937724 20068231 18669648 19652693 18590585 12124778 10656688 17660363 20068230 15917306 9892021 19651622 20058876 16964243
CDK1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7575488 18590585 17303408 8087847 27175585 17570479 17660363 15279786
CDK1 CUX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11584018 17570479
RB1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
CDK7 CDK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK2 RB1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK7 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 18767875 11113184 25271736 7880532 19690332 19667075 15703371 14597612 20360007 21565702 19809470 15302935 8443411 7533895 10085115 15671017 17095507 10886368 17386261 20068231 18452278 9244189 8069918 11840777 1396589 17570665 16325401 16327805 25788262 11959850 15530371 11532001 19056339 9130709 14551212 17192257 19847258 22505032 17884153 20147522 12648680 11900249 16697054 93010995 8393783
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7553852 20160477 23602568 25271736 18239684 28446188 23226679 10386600 19270695 26496610 16189514 25852190 26186194 25788262 9858587 22770219 15355997 10559858 23807222 22311674 16979657 9636170 19686743 19270694 18604603 23455922
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CDK2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 77.0 1.0 Omnipath 26581405 9315635 17303408 18692063 23437375 19413330 20871633 26148348 28806746 15279786 16326706 8626527 21902831 14627988 7575488 9190208 21697511 9139732 20068231 17570479 16189514 12006580 11420722 18669648 15811853 18590585 27507850 17380128 23160093 19638577 1756735 20418918 19262748 17660363 11777937 10499802 19651622 20058876 15173007 22263797 10207050 8756624 10542199 19664994 24466208
CDKN1A CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23397142 10428966 17050006
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
KLF4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10749849 23884787 18483411 21652709 23861801 19737957 21132436 21224073 22750490 21763782 18645021
E2F1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9748148 9191053 16923815 17008321 10030670 10702805 15048076 17167174
RUNX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21913213 17438369 19179305 15107836 12391164
JUN CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11136975 12717415 21278055 10506225 19628677 12054510 18094076 10072388 18210215 10733944
CUX1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11584018 12438259 15812824 15269344
MYOD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10373569 25211658 18211587 18521215 16351709 17959144 14749395
SKP2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 32035614 25241761 23261596 17679094 15998794 17477906 19686743 16376880 15980415 18794347 13678583
CDKN1A E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
CREBBP STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15695802 11574547 10454341
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
GOSR1 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
STX5 CUX1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
CUX1 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
CUX1 STAT5B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 21330321 14660670 17698633 10935490
CUX1 STAT5A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 21330321 14660670 17698633 10935490
E2F4 CUX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 18347061
CUX1 NGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 8846003 18056468 16275928 23785138 12821676 21105874 20659559 10544233 12619038 10900073
HNF4A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 23626788 23038264 17920062 10627496 17603092 21963511 15933209 9013589 16488887 16492670 9799805 15331348 17660447 16049268 11402042 17636037 15322103 16323215
PTPN13 DAXX â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 12702723 12724420 16498403 23069999 9184224
DAXX TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17145710 23331499 11483955
E2F1 DHFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8441401 14618416 8816912 20580656 7494286 12565705 10597240 15481443 9096302 9819401 10336493
E2F1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10567569 7929342 7565760 15867358 16299810 8137237
E2F1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11533237 16081466 16738312 16188218 15618023 14681231 16230367 15985428 8264596 18583990 16601104 14627987 15016799 11268000 10490838 11818069
E2F1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16331253 23352642 22372491 24574749 20424123 17471231 23348237 17483325
RB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 17145710 23472054 12502741 22078878 8896460 12397079 9315635 20839231 16249186 11839806 8255752 11713253 20871633 15837424 8346196 19249677 16360038 8626527 12096339 15485814 16374512 18391203 9125176 16766265 9468140 8816798 12598654 10393912 9400991 9632788 12947005 19477924 15485920 17380128 10523633 10869426 7828850 18216119 8657117 12963846 25257171 17488475 28074012 15670817 11583618 7739537 10499802 8413249 11090181 8230483 22768064 29521627 10207050 9553123 7958924 11420730 23001041 16496386 9501179 19058874 1388726 9422723
STX5 GOLGA5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
GOLIM4 STX5 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 15718469 9915833 22013193 15758030 17274799 8636227 20874812 23091056 11718716 9244307 12429822 11748249 20163571
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
HNF4A WNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10549281 20019092 22517624 16809766 22767186 19149881 15695365
IFNG ICAM1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
JUN ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11356008 12832416 9218873 20459645
IL4 IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IRF2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12479817 18281489 10859338 10454342
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
STAT6 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17878383 10626890 7635985 10201928 16621996 10528163 10982806 24968940 22078635 9548487
STAT5A IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12759422 7875295 7796811 15528362 9831114
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
IL4 STAT6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9651359 7796300 23124025 15805299 8085155
IL4 STAT6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
STAT5A IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10421786 23727894 18820682 17041005
JUN IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8996240 10772943 9889198 9133600 21989417 9310836 15546613 21454593 12594266
STAT6 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 9317131 10369418 9647237 12605697 11687571 20980261 10528163 23913966 12244176 10373589 9786931 12138096 22226123 16647686 17878383 8816495 20620946 21081493 23727894 17041005 9295035 12778491 14993689 9199300 21949021 12218118 8760793 19419769 10820389 16914450 15695802 11150515 20225206 15922518 12082548 8624821 20214667 10364072 9110977 11544308 17433443 17645498 25037220 19604304 15728480 9845517 18400747 12776189 10982806 16084752 20828825 21751242
IL4 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24508458 18852293 22142941 29925830 17306571 25428220
IL6 TGFBR2 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
JUN VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7986748 14654785 2922288 16831196
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17105733 17940019 16421203 18596035 11254551 14962367 14686613 16771680 9776360 12788789 12020969
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11905996 11733514 8717334 2111020
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
RB1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026157 9545246
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
STAT6 KLF4 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10485906 12223527 12244147 14610620 15634881 23124025 24204259
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
MYOD1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 7970718 10373569 10601020 10801445 16936743 12665587 20053773
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17145710 8155326 9083066 11729324 27908981 22666365 17404842 24224055 25611061 14985763 9290260 9857023 28090201 12067229 23772401 10490030 11114882 27229480 1706478 11738045 10713102 9547236 1849459 9775403 17409494
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
NGFR NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 8155326 10985348 9099755 8382740 11238898 1850821 7510697 11425862 8356095 25708205 10235685 10490030 1850549 9927421 7616616 1849459 7836442 1280261
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
TLE4 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TCF7L2 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22552774 12750294 26947016
TGFBR2 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 12717440 19050695 11133108 14557817 19920116 22710166 19114990 12767520 22703233 23331499 11013220 20060931 17934056 21614932 17673906 20644162 24132110 18922473 9865696 22943793 20519943 21900405 12154066 7594497 18758450 15548370 24336330 21278795 12724770 19010789 15265520 16474430 26192618 12809600 19109155
RECQL5 VIM â—¼   KO_UP_REGULATES ✅ + 1.26 1.26 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368