ABL1
|
ARHGEF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
NOTCH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
ABL1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
JUN
|
ABL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9746785
15145216
|
ABL1
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18619508
23418320
|
APAF1
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22246185
8384310
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
BAX
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11709054
|
APC
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
ARAF
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
ARAF
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
ATF2
|
IL13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19487697
22849952
|
ATF2
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17189429
17700520
|
ATF2
|
GADD45A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17700520
|
ATM
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MDM4
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15788536
16163388
|
MDM2
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19816404
21986495
|
SP1
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15837784
11466608
|
BCL2L11
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
MAPK9
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14673001
17555943
|
MAP2K1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15994315
15121878
|
BCL2L1
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
BCL2L1
|
BAK1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
BBC3
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22492984
17289999
|
BCL2L11
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
FOXO1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15817464
15632117
|
BCL2L11
|
BAX
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BAX
|
CASP12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
BAX
|
AIFM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12232790
|
SP1
|
BBC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18811981
|
VDAC1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
MAPK1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
FOXO1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15059979
15632117
|
STAT5A
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14695224
14500638
|
PAX8
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9413150
11453662
|
MAPK1
|
BCL2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
BCL2
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
HSP90AA1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18266962
|
BCL2L11
|
BCL2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23430059
23850759
|
BCL2L11
|
BCL2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23430059
23850759
|
BIK
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FOS
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16911523
|
FOXO1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15059979
10871843
|
BCL2L1
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
CDK1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19917720
|
CDK1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22071694
|
YWHAB
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12871587
5216545
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216271
12657644
|
FOXO1
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19050291
15565601
|
AKT3
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
AKT1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
AKT2
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
CASP3
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18362891
|
AURKA
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
SMAD7
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15023526
11180003
|
MAPK1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17205132
|
FOXO1
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17609436
|
FOXO1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21149440
23430617
|
FOXO1
|
ADIPOR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21194380
20125105
|
FOXO1
|
ABCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18390843
|
FOXO1
|
ANGPT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16100571
|
TP73
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21245298
10435630
|
YWHAZ
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AA1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
HSP90AA1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0908908106
19805354
|
HSP90AA1
|
NFKBIB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MAPK3
|
IER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16456541
17200115
|
MAPK1
|
IER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16456541
17200115
|
MAPK1
|
IER3
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456541
5218298
|
SP1
|
IER3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11844788
|
FOS
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7588633
12134156
|
AR
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14619959
20610535
|
MAPK1
|
MAP2K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
23241949
8412360
|
MAPK1
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16709866
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
MAPK14
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18253836
|
FOS
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7588633
12134156
|
MAPK3
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22227582
11585926
|
NKX3-1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20530667
12173040
|
FOS
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10348347
12173040
|
MDM2
|
MDM4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159902
5219425
|
RASSF1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18566590
|
YWHAE
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16511560
5218386
|
YWHAB
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16511560
5218386
|
MKRN3
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
AR
|
NKX3-1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8943214
|
AR
|
PMAIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17721441
|
RBX1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15572695
19560419
|
JUN
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22610349
23161884
|
SIRT1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21775285
|
SIRT1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16998810
|
YY1
|
TP73
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17980704
18029729
|
TP73
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15737644
|
SP1
|
YY1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22553354
|
YY1
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24369345
|
GLI3
|
CDK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
ACTB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10840940
11082319
|
AR
|
APPL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12621049
20610535
|
ADIPOR2
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16622416
|
SP1
|
ADIPOQ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12378384
|
ACTG1
|
NFKBIB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
JUN
|
SOCS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18571793
17609438
|
SOCS3
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11331873
|
HEY2
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10692439
|
AR
|
RACK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17108144
12958311
|
JUN
|
AREG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22570239
20308529
|
SP1
|
AREG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14742435
|
AR
|
AREG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23415714
20610535
|
ATP6V1G1
|
TRIM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CD247
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
HLA-DQA2
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
PAX8
|
SMAD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
FOS
|
SMAD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11854297
|
SMAD7
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
FOS
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15579469
|
AXIN1
|
SMAD7
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
STAT5A
|
MYD88
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7567467
|
JUN
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18793328
10871633
|
JUN
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12832543
11192249
|
JUN
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
IL13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21989417
15494506
|
JUN
|
TNFRSF10A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12082627
|
JUN
|
CEBPD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17965828
20506344
|
JUN
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19009553
18495116
|
JUN
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9733728
20353950
|
MAPK9
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
JUN
|
MAPK10
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19527717
7148309
|
AURKB
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17199039
16537398
|
AR
|
IL15
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22653339
20610535
|
CEBPA
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9632776
|
PIK3CA
|
ANGPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10521483
9632797
|
PIK3CA
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
SP1
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12032593
|
SP1
|
CDC25B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23160377
21242964
|
SP1
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17889508
16452190
|
SP1
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10373535
12049196
|
SP1
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12220517
19009553
|
MAPK8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16306447
|
ERBB3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17308105
|
PIK3CA
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STAT5A
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9885561
10512880
|
FOS
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19009553
18495116
|
AURKA
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19075565
20011137
|
STAT5A
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22729867
18586824
|
STAT5A
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18586824
|
CISH
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11713228
|
AR
|
CEBPD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24810056
20610535
|
ZBTB17
|
CEBPD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20426839
17471507
|
STAT5A
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16455947
12970402
|
MYB
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10706719
|
CEBPA
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19564408
24191285
|
CEBPA
|
HSPA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2247079
|
CEBPA
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10453008
|
ADRM1
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
YWHAE
|
CDC25B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12871587
5216545
|
PTGER3
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
12038972
|
GNAI1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15922020
19703466
|
MAPK9
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19638579
|
PRKACB
|
GLI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19996099
20027184
|
ERBB3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
KIF7
|
GLI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19549984
19592253
|
HSPA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
MYB
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12096342
18945670
|
AR
|
ERBB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21741601
20587519
|
AR
|
RET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20587519
11255259
|
EZH2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24457600
23239736
|
AR
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15542423
|
ERBB3
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
AXL
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
12470648
|
AGTR1
|
FBXW11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
FBXW11
|
NFKBIB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MAPK8
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19737086
|
PACS2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8008986
19481529
|
EZH2
|
FBXO32
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21546904
24213577
|
RET
|
ARTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15044950
11491658
|
GATA4
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23632743
24866243
|
GATA4
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9207128
10579051
|
SREBF1
|
COL6A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14697233
23221806
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
HSP90AA1
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CDK1
|
CDC25B
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
12107172
|
CDC25B
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
7880537
|
AKT1
|
MDM2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
MDM2
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
BCL2L2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
ARAF
|
AIFM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29777862
25852190
|
VHL
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
16678111
|
LPAR4
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BAD
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19427863
17274640
|
MDM4
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19521340
24445145
|
EGLN3
|
ATF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21951999
17684156
|
VHL
|
MIF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
21942715
|
CUL2
|
FEM1C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
33961781
|
CEBPD
|
ATF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29601799
20102225
|
AXIN1
|
AXIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22682247
20128690
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VDAC1
|
AIFM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
29128334
|
ADRM1
|
BAG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
BAD
|
BCL2
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15694340
|
BCL2
|
PMAIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
BCL2L1
|
PMAIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
NDUFB2
|
NDUFS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
NDUFB2
|
UQCR11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
NDUFB9
|
UQCR11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
NDUFS7
|
UQCR11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
BCL2L1
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9539746
|
ABL1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
CASP3
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25241761
9278461
24842904
9840926
21726810
|
FOXO1
|
PRKACB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
ACTB
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24583282
24798327
17373842
|
MKRN3
|
MDM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27107012
32296183
22493164
|
ATF4
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23661758
20102225
|
AREG
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SMAD4
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10220381
25609649
|
AKT1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
ARAF
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ATF4
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
AKT1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
APAF1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
ADIPOQ
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
AXIN2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10911903
|
AXIN1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
7025676
19131971
|
MDM2
|
ATF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27264869
21988832
|
MAPK8
|
JUN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
7148309
19527717
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
AKT1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15833858
28628118
28205554
|
BAK1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
FOXO1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
21798082
|
AKT1
|
FOXO1
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
18423396
|
JUN
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
EZH2
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23238014
26496610
|
SMAD7
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16601693
18593713
|
YWHAB
|
CDC25B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
15173315
5217050
|
AKT1
|
APPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
JUN
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CDC25B
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
BAX
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
MAPK9
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9405416
|
BAG1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9305631
7834747
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
ATF4
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AR
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BCL2L2
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BTK
|
GTF2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BBC3
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
APC
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
SP1
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CASP3
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
SMAD4
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ABL1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BCL2A1
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CDK1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ABL1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
BAX
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
YWHAZ
|
ARAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8009399
19933840
|
BCL2L1
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
FOS
|
ATF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
25241761
23661758
1827203
20102225
|
BCL2
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
MAP3K5
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
BAG1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
NDUFB11
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
NOTCH3
|
RBPJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
YWHAZ
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
1204662
8005727
11526496
|
VDAC1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9843949
16189514
15637055
28760928
12767928
|
CKS2
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
26496610
23602568
33961781
26186194
19786724
25852190
32707033
26344197
18471975
|
AKT1
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
VHL
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
6542648
18323857
|
SP1
|
SMAD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10878024
18215124
21297662
16714330
11114293
22033265
|
SP1
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25879517
10506225
16713569
33572115
16478997
17215518
|
BAK1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ATF2
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BAD
|
BCL2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BBC3
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
ATF2
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ATM
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9168116
17409407
10212258
20798688
11375976
9168117
|
ABL1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16702947
25624478
12110584
|
PTPN13
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
061869
8311472
17240990
|
AXIN1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16199882
22682247
10228155
29045831
18786926
20128690
19131971
26496610
10811618
9734785
29713058
23277359
17510365
|
APC
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10200466
17297457
9973322
|
AXIN2
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10966653
10911903
9554852
|
JUN
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8027667
20102225
28514442
16511568
23661758
15546613
26496610
2320002
20195357
10327051
1827203
9445037
20511396
10207054
25609649
33961781
|
FOS
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
1828107
25416956
32296183
16511568
23661758
20195357
33961781
1827203
26186194
25609649
20102225
|
SP1
|
ATF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2145272
12760745
|
ATM
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15546863
15899889
|
YWHAB
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GZMB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11287608
|
MAPK3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19777442
10597268
12566304
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
BCL2L11
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22492984
12242151
|
BAK1
|
AIFM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12232790
23003569
|
BAX
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
SMAD4
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15886208
16603637
18620728
|
AKT3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14766748
15642728
17525161
|
PMAIP1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15705586
|
BBC3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15574335
|
BBC3
|
BCL2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
BBC3
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
BBC3
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
BBC3
|
BCL2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11463391
11463392
23430059
|
ZBTB17
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21167753
19549844
17082179
|
JUN
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14623928
17262823
19335069
|
PMAIP1
|
BCL2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15694340
|
ACTB
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AR
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21310825
20610535
18196538
|
GATA4
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15100413
12468531
17272823
|
BCL2L11
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
23430059
23850759
9430630
|
BCL2L11
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
23430059
23850759
9430630
|
MAPK14
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15486195
17570479
16818494
|
BCL2L11
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12118373
|
AR
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22038727
20610535
23554843
|
NFE2L2
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
10510468
|
CCNB1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
34224728
18337751
9891079
24508230
17431037
9560267
14681455
17283331
8662825
19162005
16159883
25852190
20360007
19879842
12397081
11331587
9247342
26496610
20228808
25750436
12612082
16784539
23602568
20733055
27626412
20367638
8397206
10973963
9001210
20956543
33037310
8397207
23543736
32707033
2570636
30674583
10716937
27030811
18408765
24358021
20974803
7799941
33961781
26186194
17679094
23799914
8463339
26344197
|
YWHAZ
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
11237865
8005530
3540605
|
FOXO1
|
SLC2A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16670091
12414908
17317207
|
FOXO1
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20088826
17599040
15632117
|
RBPJ
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
MAPK1
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK1
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11585926
|
MAPK1
|
GTF2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10648599
|
MAPK3
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
MAPK3
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
AR
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
AKT1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
MDM4
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
10629057
32300648
25512388
21988832
25384516
25809483
17616658
25105592
12874296
31796886
29295817
32075226
20705607
17301054
22493164
25703327
27777309
29523541
27617579
23028042
20473904
22120712
22333590
22902369
22745160
12860999
19432880
21925390
28205554
25659040
19838211
33985974
16055726
25961923
32427989
18566590
22266850
18219319
29057323
10608892
30598450
29524278
25825738
17159902
24813712
31024344
27621617
15604276
29262653
19619542
10218570
28628118
16227609
10827196
12393902
24755078
20724842
34551723
27215386
11606419
20484049
12370303
23671280
26001071
26720344
33961781
12483531
23946421
19683495
26359458
|
SP1
|
MIF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21087445
18034423
|
SOCS3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18481982
9869640
19649319
|
RBX1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19327355
17183367
12149480
15448697
10230407
12481031
29547696
32296183
11861641
15601820
30349055
22405651
25540389
10579999
19250909
21822215
21778237
29958295
22863883
33961781
33504946
28591624
17132228
|
RBX1
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16503656
23401859
33567268
12048197
17353931
15601820
26735018
24469044
30349055
33504946
33137104
12604794
16261165
16325183
|
SP1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23843607
20160399
23704280
|
AKT1
|
SMARCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16568092
|
YY1
|
NDUFS8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
11955626
15004004
8882641
|
YY1
|
NDUFS8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11955626
|
CUL2
|
VHL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16503656
22086907
28514442
9751722
10823831
15060148
11865071
21942715
27697924
20049704
26743088
11779168
17439941
12604794
9122164
21145461
15611064
19030229
21685897
12048197
10421634
28775317
15601820
10449727
24469044
11384984
10587522
18173839
22286099
17339318
16261165
16611863
23401859
15966899
22234250
9447969
17353931
26751167
18323857
25661653
33137104
11024059
18187417
18523483
10318914
26735018
24981860
33961781
31444342
26846855
17132228
|
ATF4
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
1827203
20936779
23661758
|
NFE2L2
|
ATF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21087962
23618921
20185790
|
ATF4
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21044953
24939851
|
ATF4
|
EIF2AK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23009153
21146245
17141186
|
AR
|
CDK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
15790678
|
SP1
|
CDK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12840223
11297539
|
CALM3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9859994
2550447
19608982
|
CALM3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
ADIPOQ
|
ADIPOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
26578976
12878598
12802337
|
ADIPOQ
|
ADIPOR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
26578976
12878598
12802337
|
SREBF1
|
ADIPOQ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18669923
15037635
19932681
|
AKT1
|
SMAD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16362038
23397142
|
SMAD7
|
SMAD4
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
11279127
15265520
23784029
|
SP1
|
SMAD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21421563
|
SMAD4
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12374795
10022869
|
FBXW11
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14988407
|
SMAD4
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12226080
16713569
|
SP1
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16714330
10843994
|
JUN
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15579469
10843994
|
AXIN1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16601693
|
APC2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9601641
10980707
|
JUN
|
STMN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17182846
15474303
|
JUN
|
GZMB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
|
SP1
|
NDUFS8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11955626
|
SP1
|
CISH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8411351
14644509
17625116
|
SP1
|
AXL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18522535
11953011
20977427
|
SP1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7559553
|
SP1
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14561739
16452190
9295358
|
SP1
|
ABCC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9865734
23765166
|
FLT3
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17356133
12796379
|
CEBPD
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10373535
7910803
10623469
|
YWHAE
|
GLI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8009500
038232
19996099
|
YWHAE
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
MYB
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17242210
|
RET
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
PIK3CA
|
ARTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
PIK3CA
|
ALK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11280786
11110708
18097461
|
ERN1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18471544
27009865
|
GLI3
|
TNFRSF10A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20562908
|
BTK
|
GTF2I
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9837922
15096481
10373551
9012831
11313464
19214191
11373296
11934902
14623887
|
MAPK10
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20630875
|
MAPK9
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20630875
|
SREBF1
|
SLC2A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16787385
22735681
|
BAD
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
HSP90AA1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
NDUFB2
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
ADRM1
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
ACTB
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
BAD
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
CDC25B
|
FBXW11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
FOS
|
ATF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
25609649
|
YWHAZ
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
20618440
7899808
|
BAX
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CDC25B
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CDC25B
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
NDUFB11
|
NDUFS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
ATF2
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
YWHAZ
|
CDC25B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
12764136
5216396
|
CKS2
|
CCNB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
28514442
26496610
33961781
19786724
30674583
18471975
|
BCL2L1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ARAF
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
BAK1
|
BCL2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
MDM4
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
15604276
5217417
|
MDM4
|
MDM2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.93
|
0.93
|
mint
|
17159902
5219425
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
AKT3
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
BAX
|
BCL2L11
|
â—¼ PROXIMITY
|
✅
|
|
0.94
|
0.94
|
mint
|
7034061
19427863
|
MYD88
|
IRF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
15361868
16484229
|
BCL2A1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATF2
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
BCL2L10
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
BCL2A1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
AKT1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
AKT1
|
FOXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10358075
25241761
10358014
16076959
31844113
18786403
|
ACTG1
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8153045
21516116
|
TNFSF10
|
TNFRSF10B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5211930
10542098
|
BCL2L10
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
AKT1
|
MAP3K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
ABL1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
19427856
10212258
9461559
21653319
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
AKT1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
32450252
25241761
18332867
12145204
19166854
15527798
20856200
11715018
23397142
11504915
11923280
21930127
|
NDUFB11
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
JUN
|
MAPK10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
MAP2K1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
BIK
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8816500
32296183
16697956
15694340
9525867
9463381
17289999
33961781
12853473
9488477
31387940
|
BCL2L1
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
SOCS3
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MAP2K1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
TNFRSF10A
|
TNFSF10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AR
|
NCOA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BAK1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
MDM2
|
TP73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL2
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
JUN
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
TNFRSF10B
|
TNFSF10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ATF2
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
FOS
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
NDUFB9
|
NDUFS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CCNB1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
7834748
9388232
17446862
9463381
20603619
10611223
14681455
11483855
33961781
19168699
15990872
9305851
15849194
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
BBC3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15694340
16697956
14681455
17289999
33961781
11463392
26431330
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
ADRM1
|
PSMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CUL2
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ADRM1
|
PSMC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
CKS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMC2
|
PSMC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
JUN
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFS7
|
NDUFS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ATM
|
ABL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
17145710
17303408
22334513
11375976
11804596
23331499
21071413
16163361
17570479
18988627
9168116
23847781
9168117
20798688
15964794
19788416
9561848
22084676
12607003
10212258
15459660
11877377
15686624
17409407
|
CDK1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
19651622
17081983
2183353
18691976
18452278
18669648
|
ABL1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
23331499
26546517
9461559
15279774
15033353
19427856
11684015
19285032
20841568
15330855
15212693
10212258
12359302
|
ABL1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
23318434
10391235
21188172
25666857
20841568
11278685
23331499
27294865
25893286
21199784
17535448
21051857
10391250
18988627
10391249
28690977
25341038
19788416
26512706
10391251
20195489
12070014
15459660
20057499
15686624
21435002
11223036
|
ABL1
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
12445832
15212693
12573241
8629002
17932028
10051622
25704810
8630736
34162728
9188445
16497976
20841568
27602755
11598012
9326643
|
ABL1
|
RACK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
27170279
21124943
20841568
21978545
19423701
|
ABL1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20651945
29262653
26148237
19075013
20841568
28690977
29348869
|
ABL1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19818398
18619508
10637231
20841568
14757045
15302935
|
ABL1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
23331499
12110584
20651945
29065514
22352870
16702947
25973395
27626309
21081495
27956626
20841568
14757045
19738896
15212693
28690977
|
ABL1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24836440
8940193
20841568
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
BCL2L1
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
10811864
9488720
12963020
9539746
|
APC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
APC
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
APC
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
APC
|
RBX1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
JUN
|
â—¼ SHARES_COMPLEX
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
APC
|
RBX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
AXIN1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16199882
20128690
19131971
11297546
9554852
22682247
10228155
26496610
23277359
10811618
9734785
|
YWHAE
|
ARAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19608861
20936779
25852190
17979178
|
YWHAZ
|
ARAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19933840
20936779
25852190
20052757
|
ARAF
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
18039929
8131746
8394352
24114843
15175348
15466476
94178255
7936666
7731720
7873542
7624324
8157000
8039496
8621729
|
ATF2
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10366004
10327051
8530413
12052888
15068801
12751796
9502786
9141200
9252389
11238729
12903123
19255142
11736649
16511568
9819389
|
MAPK1
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10777545
17081983
21098032
9430721
12110590
20068231
19690332
15304344
19413330
10878576
15192015
7737129
18669648
19647037
|
MAPK3
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10777545
12110590
20068231
15304344
15192015
19647037
|
MAPK10
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19436832
20506250
16393692
8654373
20028971
11274345
|
MAPK9
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17145710
17081983
18767875
20506250
25416956
19255142
19413330
20028971
8654373
12788955
11994493
11566021
10777545
7535770
8709204
17875713
20068231
16393692
15192015
7737130
18669648
10066798
602896
11896587
12110590
32296183
11971971
19651622
19436832
16533805
11865055
19822663
11823524
31515488
7737129
11274345
|
MAPK14
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
104.0
|
1.0
|
Omnipath
|
17081983
18767875
21098032
20506250
26359454
19690332
11060298
19413330
12788955
10085140
22037767
11566021
17079470
19647037
10581204
10777545
7535770
23331499
7839144
19324872
21071413
21614932
20068231
16393692
15304344
17570479
17380123
18988627
7737130
18669648
15187187
9305639
7737129
15140942
602896
11896587
17548358
12110590
7824938
8663524
33893075
12024021
11078583
11971971
9707433
17258390
10821277
19651622
19436832
11259586
27726305
11781825
9430721
27142525
10909971
12118074
15569672
15212693
9753474
11274345
10903740
26987986
|
MAPK8
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
17145710
11279118
17081983
20506250
12958075
9162092
19255142
8654373
20028971
15105425
17626013
12788955
11566021
15550563
10777545
23331499
7535770
15068801
21071413
17875713
9317150
16393692
15304344
18988627
7737130
26538579
21444723
602896
11896587
12110590
7824938
11274345
12874243
11971971
9399639
19436832
16533805
9670022
9029150
11865055
9207092
12804775
7737129
15212693
9405416
|
SMAD4
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10085140
|
PLK3
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21098032
21296815
20068231
|
ATM
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24357804
25545367
15916964
28212892
25689427
|
ATF2
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
25609649
20102225
15546613
2320002
10327051
1827203
9445037
26496610
20195357
16511568
20511396
10207054
8027667
23661758
31515488
18641343
1828107
|
ATM
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
AURKB
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22099307
27493659
|
ATM
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18662573
16122425
25077544
16122426
21113148
17525332
|
ATM
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23148884
18619531
22826432
27156884
29144413
29294106
23046908
17609267
18171990
|
ATM
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
66.0
|
1.0
|
Omnipath
|
14654783
12383858
17936559
20651945
17303408
19816404
10611322
23150762
23277204
23386996
26416444
27258263
23002429
11331603
15865937
21556066
16163361
23708100
17570479
20514355
22264782
27177180
18265945
28690977
23847781
22264786
15140942
15964794
19788416
22624716
25201202
27462439
12607003
28050229
32350255
22649771
27956626
15459660
22976441
25247188
28904407
11877377
21859827
24534650
23405218
29290977
27568562
|
ATM
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
20651945
16943424
29065514
16511560
20860841
28690977
17512070
23002429
16163388
16082221
28096294
15788536
|
ATM
|
RASSF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31175105
22438769
19962312
27322327
10608806
22389451
|
BCL2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BAD
|
BCL2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
12107820
12175651
12444011
12767520
16931767
19030972
19641503
21540285
22039431
9346240
|
BCL2
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BAD
|
BCL2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
12107820
12175651
12444011
12767520
16931767
19030972
19641503
21540285
22039431
9346240
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
CDK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12049737
14551205
15279786
17303408
17660363
18414028
18590585
21725609
7575488
|
GZMB
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
10364179
10805722
11062502
11085742
11085743
11287608
11583622
11832478
14499263
15536084
15607806
15637055
15713684
16106370
18287025
20189481
24248158
24795729
8432729
9727492
|
MAPK8
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
11983683
12189144
14673001
16166315
15526032
29795446
15907327
14967141
15725726
17555943
|
PRKACB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
CDK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
18071308
16166315
24677263
12965220
15907327
26287183
21858202
25618528
12049737
16009721
19124971
16403219
17498878
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
BAD
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
9305851
17145710
11483855
16697956
9463381
15694340
15849194
20603619
15990872
11583631
8929531
7834748
9388232
17446862
19168699
|
BAD
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
11483855
15694340
20603619
10381646
32296183
22000515
12115603
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
BCL2
|
BAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BID
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
23782464
17289999
11175253
10950869
12624108
23604079
12242151
|
BCL2
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
9463381
14980220
11206074
17289999
26004684
11728179
20836993
19168699
|
BCL2L1
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
22705850
9463381
22516262
31467278
32814053
9020082
23680104
34098062
18178565
15901672
16189514
17446862
20836993
23055042
19060904
17289999
32296183
10085290
14596824
15292519
29997244
31515488
11175750
9027312
|
BCL2L2
|
BAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17289999
18178565
25416956
10381646
15901672
32296183
|
BAK1
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9843949
10365962
10639121
|
BAK1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15901672
11571294
16189514
16439990
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2L11
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10198631
12419244
15486085
15724238
23430059
23850759
9430630
|
TP73
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18034190
17346710
18421303
21245298
10559267
18418051
18644986
17521288
19067706
11748232
|
SP1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11278953
10510469
11748232
|
NKX3-1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12203124
17213822
19801665
8183578
21594902
17486276
23291169
19266349
19242108
19054058
19136938
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
MAPK8
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15525785
18471544
16709574
|
AKT1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26763134
14766748
15642728
17525161
|
BCL2L1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
59.0
|
1.0
|
Omnipath
|
22705850
18981409
21458670
28202514
11283018
17525735
29749471
21567405
9388232
18547146
19074440
16151013
21199865
18178565
26496610
16189514
15486085
26186194
17289999
9111042
12419244
25241761
14963330
12853473
9742125
9153240
19427863
21852238
14766748
21671007
15131699
9670005
8596636
24814347
9824152
9027312
|
BCL2L2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18981409
17289999
18178565
21199865
17452531
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
BCL2L11
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22492984
26186194
17289999
12419244
11301022
12198137
17525735
21199865
18948948
23235460
11997495
15486085
12242151
23374347
19427863
15721256
|
BAX
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16189514
10365962
9843949
12767928
|
BCL2
|
BBC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BBC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
TP73
|
BBC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15650240
19421143
18565851
15865927
17700533
18579560
|
TP73
|
BBC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11463391
19788416
11463392
14634023
14684737
|
BBC3
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
|
BBC3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
19074266
28202514
15574335
|
BBC3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
11463392
|
BBC3
|
BCL2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
|
BCL2
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
BCL2
|
BCL2L11
|
â—¼ PROTEIN_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10198631
11704864
15486085
15724238
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9430630
|
RBX1
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
GATA4
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18653721
17098826
19602725
16469847
|
CEBPA
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16254192
18987666
23814099
15713621
12970736
|
SP1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
14660675
20435036
12032828
10542244
15713621
|
NKX3-1
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12679484
15817464
17191317
22266868
22869582
24273454
21940310
8183578
23313858
9581775
14684736
24098340
17486276
19137013
19266349
16316993
22331597
|
MYB
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22101269
23675407
20237898
17823980
20659323
10692454
9096387
11675351
12384144
16088151
9823328
|
AR
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17655826
11567031
23160675
20610535
|
CASP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10409669
9395403
20139069
11948397
|
MAPK3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115213
10669763
9735392
11323415
21785723
9738012
10677502
23272207
25826088
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2L11
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
17145710
9463381
16697956
9430630
17074758
17097560
19805519
18498746
26004684
14517273
10198631
21199865
20836993
26186194
15694340
17289999
17692808
11301022
23845444
21671007
9731710
|
CDK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
24097825
24677263
23638364
19917720
27231850
11774038
11326318
10766756
|
MAPK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
9115213
10567572
12039864
10669763
15225643
11323415
21785723
9738012
11337027
10677502
23272207
|
MAPK14
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
29050237
16714293
19336399
11495898
|
MAPK8
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
12421819
26609913
17097560
16738310
21726807
10567572
21993018
29950132
20919655
22848813
15225643
19029119
9738012
18570871
9115213
12039864
11323415
15733859
18471544
15703383
23329792
10677502
|
AKT3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
PMAIP1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10807576
21454712
15725726
|
BAG1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9305631
7834747
8947043
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
BCL2
|
BIK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17145710
22705850
9463381
16697956
17289999
9488477
9525867
12853473
8816500
9305912
32296183
|
BCL2L11
|
BCL2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
9731710
32296183
|
NKX3-1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22869582
19439449
23677993
21354697
11450946
16316993
16214938
|
STAT5A
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10979976
10428780
20585448
10727459
12946994
10435632
11731240
10428030
10964754
15545372
19339209
11756417
16214938
15626738
|
MAPK8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
10617621
25241761
15733859
12633850
18471544
|
STAT5A
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10428780
19211554
10652277
11085453
10435632
10428030
11756417
|
BIK
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
22705850
26871637
16697956
15694340
7478623
27107012
11342619
9525867
31515488
12853473
16189514
32296183
9027312
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
PMAIP1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17145710
10807576
21454712
15694340
15725726
|
BCL2L11
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
17145710
16697956
9430630
17525735
22516262
18498746
10198631
21199865
20836993
26186194
15694340
17289999
27013495
32296183
23245996
11859372
19427863
21671007
14596824
9731710
16260615
|
BID
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
9727492
19074440
16697956
15694340
17289999
25241761
22464442
14963330
16189514
27159560
24814347
15574335
|
PLK3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21336504
21840391
|
BCL2L1
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12767928
17209561
16189514
10365962
10737788
|
CISH
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
TCEB2
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
CUL2
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
BCL2L11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
FOXO1
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17702754
16006742
12913110
16123151
19690465
19757185
|
JUN
|
BCL2L11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17702754
16153157
23285061
22869147
21439021
|
MAPK8
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15486195
14555991
18691976
22071694
12591950
15470142
18174237
18498746
12818176
|
MAPK9
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15486195
14555991
18691976
18174237
12591950
15470142
12818176
|
MAPK3
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
15486195
25915848
17604722
14555991
28474232
19150432
18174237
12646560
12818176
15486085
15212693
14681225
|
MAPK1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
15486195
17604722
14555991
28474232
19150432
12646560
16282323
12818176
17570479
15486085
15212693
|
AKT1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17145710
16282323
30923040
|
MAPK10
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
15486195
14555991
18691976
12591950
15470142
18498746
12818176
|
BCL2L11
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
9430630
16697956
15694340
17289999
21199865
9731710
32296183
|
BID
|
BCL2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
16697956
17289999
15694340
|
BCL2L2
|
BIK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
27107012
25416956
10381646
32296183
|
GZMB
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
10364179
10805722
11062502
11085742
11085743
11287608
11583622
11832478
14499263
15536084
15607806
15637055
15713684
16106370
18287025
20189481
24248158
24795729
8432729
9727492
|
MAPK8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18594987
25326334
25077544
27374471
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
GZMB
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
15014070
17179148
19103589
10805722
17283187
11583622
12808108
9727491
15569669
11085742
11085743
16415351
11696597
|
NKX3-1
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21850191
15705778
24961145
20599703
|
GZMB
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19254476
17179148
19103589
17283187
16495481
8700869
9694885
12745270
15569669
9233763
16415351
8755496
11696597
|
MAPK14
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
14970175
33176141
29414778
|
CASP3
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8626669
9535906
16713569
9208847
|
CASP3
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25241761
9278461
21726810
24842904
9840926
|
CASP3
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10998058
10082566
11684015
|
CASP3
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17544405
12124386
10579725
|
CCNB1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CDK1
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17660363
18414028
18543256
18590585
18995830
19004803
19652693
19686080
23485469
7575488
|
CDK1
|
GADD45A
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17660363
18414028
18543256
18590585
18995830
19004803
19652693
19686080
23485469
7575488
|
CDK1
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
TP73
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19861536
11593387
19067706
|
CDK1
|
CDC25B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
8119945
1836978
12754270
20360007
8440392
10827953
12411508
|
GADD45A
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18942077
10362260
10973963
12124778
16189514
|
EIF2AK2
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
25149538
20395957
|
CDK1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
18408765
18356527
27035875
19473886
24948874
25590687
23029264
19124971
22280365
|
CDK1
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16880739
|
CDK1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15735705
|
CDK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
26573794
12569365
22275373
25704883
17043241
23321516
9725910
24480624
21799006
24424504
28062857
21820033
25950519
28415597
27450452
25691442
21782001
|
CDK1
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17303408
18073536
1075565
15279786
7575488
21640712
9733650
8440392
17570479
9141461
19652693
18590585
9585407
12124778
18786381
17660363
15917306
9268380
12107172
17568790
20801879
12766774
|
CDK1
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19107194
17570479
24011073
28756945
|
CDK1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25398907
28831131
20150555
22266860
|
CDK1
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
83.0
|
1.0
|
Omnipath
|
17081983
18767875
9731215
20230923
19690332
17693683
11135364
19413330
18187866
19664995
19415658
18578522
16083285
20068231
18452278
94064639
1737801
18491316
18669648
8245003
16427064
93315482
17287340
16094384
19651622
20058876
8376365
8325880
17924679
18220336
19664994
18707149
8125092
8325881
16964243
33839152
18212344
|
CDK1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
28.0
|
1.0
|
Omnipath
|
25841987
34381492
25691891
27941792
27653691
23549878
25800736
22187039
23241245
25038756
25334066
22964433
27716745
20935635
21131960
29576612
33593912
21123648
23438432
21659531
26552009
|
CDK1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15985436
17620410
12676926
|
CDK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23799914
34224728
20117088
16784539
24358021
24508230
19470789
10973963
17283331
20228808
18347064
11242082
12397081
10362260
24582498
15582998
20367638
1833185
12447691
9001210
2570636
24101512
23543736
11331587
12524548
22726437
27626412
|
CDK1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
25971971
8114697
11684694
17570479
12609978
|
AKT1
|
FOXO1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
15987244
10358075
10102273
12857750
|
FOXO1
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24478438
16492665
18202130
20868688
22511764
|
FOXO1
|
FBXO32
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21798082
20079455
15109499
17540700
15125842
|
FOXO1
|
TNFSF10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20200974
23630076
15632117
12351634
|
FOXO1
|
ANGPT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17030814
16100571
20213583
18006475
17960565
17258205
15132996
|
FOXO1
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18301748
20713551
23763570
18390843
|
SIRT1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
24003218
22013015
14976264
18235501
15220471
14980222
22395773
15788402
15692560
|
AR
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
18391971
17202144
16713569
12482965
|
AKT1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
90.0
|
1.0
|
Omnipath
|
21440011
10358014
11756412
10358076
31308176
20452955
21798082
11410590
20398329
11311120
11544290
28279977
10217147
15132996
23331499
19216069
11237865
20214616
11463845
16076959
11030146
12228231
9829964
18951090
23180781
17570479
10102273
18593906
17646672
16680151
12456685
18423396
18985696
18988627
17962350
30728292
16670091
18786403
14664696
25241761
16341064
11980723
10358075
2984676
13679577
12560069
10377430
11251083
17680028
2987962
17254970
11864996
20041807
|
AKT2
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
17646672
20214616
11463845
20705244
20452955
9829964
20398329
10102273
18593906
16680151
10377430
10217147
|
AKT3
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
17646672
20214616
11463845
20452955
9829964
20398329
10102273
18593906
16680151
10217147
|
GADD45A
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23109003
12748288
20626350
15735649
|
HSP90AA1
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
23220880
30854046
28274957
18039657
16843263
26545934
22046346
23843458
30314968
23948973
|
HSP90AA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
1525041
19805354
20048054
15861399
17974989
26342197
17353003
26196320
16713569
27903893
1540595
21157430
19706771
|
HSP90AA1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19356729
18266962
10995457
25714412
16189514
12176997
12586360
15843522
|
MAPK1
|
IER3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12356731
16456541
|
MAPK1
|
RBX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
31434245
22955283
12748172
16009132
|
NFE2L2
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19454702
23708697
17467702
21808062
|
SP1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12220517
16797880
20506264
20121399
20882567
18372343
10727414
21170990
17889508
|
RET
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
19901323
11522789
91184134
16156666
16497976
15592455
12571246
19415658
11826406
17389395
18578522
21109534
20068231
18452278
18669648
16153436
11522288
18691976
1378617
15972258
15935618
16094384
12388769
11971971
19651622
21842857
28450419
18707149
17016520
21455180
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAP2K1
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
149.0
|
1.0
|
Omnipath
|
21675959
9694850
17081983
10757792
11319218
18799465
15592455
12788955
19415658
12697810
17389395
9447970
15342917
8226933
15851026
12270934
12644307
17255949
10998418
11242034
1378617
1381507
17906627
11986622
8376945
8157000
7992057
11948414
9731057
19651622
11251083
11266467
18707149
14743221
11279118
11704645
12750173
12932319
16497976
11337027
23331499
12048245
7559390
17272394
15811950
19494114
18669648
18691976
11741894
15972258
19053285
16094384
17192257
7898932
24623782
9166761
19369195
21336309
12920017
15466214
17016520
19901323
1712480
19690332
11823456
9032297
11134045
12876277
19534553
10995751
20068231
21506533
8223433
8248196
16153436
12594221
10567369
19933846
17563371
11730323
29175850
11352917
16135787
15951569
19058874
15212693
23241949
9560161
91184134
18083107
16887817
18578522
17569879
21071413
9148935
18452278
1330321
8670897
19541618
10777511
15935618
12925710
11971971
9765155
11136732
11118451
12082107
12952943
10746662
21768338
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9804779
25241761
18775330
10194762
8226933
10996427
9604935
8388392
12091337
|
MAPK1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8072547
11313929
15378002
12531896
12853483
23720779
9662434
1496019
17570479
1922387
11278277
11739718
16023596
20086174
25557171
7737130
26755651
8224842
14676207
17920329
25201974
9022811
22327296
18650425
8137421
18443042
12881422
18572021
17001009
33767435
7744008
23616010
26745678
14617628
11432833
16819515
22606284
12040039
|
MAPK1
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
26881937
20630875
22028470
|
MAPK1
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14701740
|
MAPK1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19318349
20882567
16377629
18775330
8226933
14744793
16079281
11904305
9604935
15212693
14593115
8388392
|
MAPK1
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12801888
|
MAPK1
|
EIF2AK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17404396
9528799
|
MAPK1
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10627507
10915800
18669648
|
MAPK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18511414
9725910
10318905
|
MAPK1
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
12134156
20506250
15547943
8248197
7816602
15084594
12697810
8226933
20068231
18452278
12738796
16393692
17255949
17439715
15187187
19541618
23109003
19565474
17722974
17052211
7588633
8545107
16055710
8388392
18039929
12972619
18775330
21098038
9604935
11274345
|
MAP3K5
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10644746
12775720
23857585
8622669
15632108
21177868
17392283
16648474
27577261
33685990
17438131
20570725
17442957
20068182
15817653
15917303
21835346
20799279
16709866
12101183
|
RET
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
19901323
17081983
8622669
16497976
15592455
15735649
7535770
17126298
16083285
20068231
18452278
18669648
16153436
18691976
18088087
17548358
15972258
10781613
19651622
15674326
7750576
17016520
15659558
|
MAPK14
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19638579
12400006
17570479
16851915
11333986
15629715
|
MAPK14
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
23397142
11238443
11274345
12697810
|
MAPK14
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15187187
18039929
12738796
11274345
12697810
|
MAPK14
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21902831
30022044
17570479
27494834
28067271
|
MAPK14
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
30644418
24424504
21820033
16282370
|
MAPK14
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12475989
17689131
17570479
25483191
|
RET
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
551.0
|
1.0
|
Omnipath
|
15956760
25485910
17240116
20385359
12527803
17621270
23612968
18212246
21860413
18097051
18851832
10645003
25679764
21423210
15007380
19934253
19935718
22356909
9677429
15781651
10849428
17188005
20667468
14625304
34380633
17377139
21423211
20010870
26186445
20736304
12376318
33627405
16740736
21561860
15004239
17901130
15212956
15897464
15143154
18819921
17157789
26297582
12138104
11777927
22158866
23195225
34473994
20494825
14963038
16778204
17391526
27683117
22689060
12444552
31933886
15059947
26823016
15657432
19377875
17142325
15486045
21460222
23431142
11159838
27654866
19941816
14718389
34375550
18593598
17360704
23997214
24501773
16163708
10604992
15297577
17106060
24396487
25893857
20361349
16822962
12554776
18454177
29434871
34530870
16141331
12356731
19169277
20543098
17685427
21478906
18463290
16250012
20534535
21228323
7535768
26617336
15963258
10617652
17196532
19995915
10464310
15315965
12082540
21685939
25730857
18305109
25703330
16928771
15681433
11083859
16076871
20395206
23146907
26246800
21454539
12660819
21220474
15866871
15637081
19858202
34403210
18032526
16195541
21829454
16459330
17209045
12808105
11585739
16162500
25833830
18246127
11864968
24418169
15935618
19925796
20160123
17056593
14998784
18215133
10508618
18775330
18760948
12952943
21768338
17317777
8155326
22258404
15788397
26919095
28213521
21192818
33798093
15851026
26242183
12402043
21868357
17064352
20927383
16380505
15035987
21454675
18957207
19193766
21188622
19050043
16904111
19888469
26073130
20185553
15282551
16790523
23405013
11994288
17510392
32081857
18941537
20930115
19106095
11043579
21499301
20145126
24427291
10958690
15939799
19088846
19286657
18424438
15308678
18198175
27323814
24338688
24252946
19956644
21478903
12014987
23017243
17525129
12511559
17615152
16505244
20122898
12077249
17123942
26035354
11278407
15665049
20531297
17292825
14976148
16449644
16461767
23361053
19261611
11502744
25658205
12149254
30327409
17560175
24352879
26586479
26804906
25779944
34125833
19118012
11352917
16740725
11884401
16464862
16641227
27323830
18063582
22955283
24561529
10779765
10542198
16135812
23564461
17210721
24469048
24803537
21602434
17110601
21045017
11073973
10597231
23687376
34556812
17341659
18692468
17579083
12384403
21408150
25417160
11752053
23325789
17371847
11970985
22327338
26265441
16840783
17283152
26616862
23188829
17239630
21487005
11024037
17053147
24363437
25682201
20234004
12391272
23644655
25638159
20808799
17922836
20129247
24913355
18451171
25483104
26296889
21081844
17404396
11287604
18263590
26317416
15541367
16467309
12765939
16331263
16498402
20485667
11230338
16387841
19543320
7687743
20228268
15630487
16774943
16710359
10803464
16844778
16574647
15994317
17495961
21215800
17590453
26382850
19002495
12909616
20599567
12558965
10667594
24711455
17255109
16038803
12370087
21072043
20008839
18805968
10206983
11875080
20231899
21499296
21908610
16002410
12821943
24292678
17525735
17928416
21057531
25236495
17283137
21659545
24403530
16919488
23378338
22973961
18847491
16682955
20840866
16153436
23542175
24492000
12526087
26556867
12133965
12433918
20065107
14610044
11959800
15580310
21730285
11046056
9124279
14707024
26725216
16452220
22212957
25811962
15696170
11416124
20498373
17157787
21653826
16149052
20022946
34262144
16434970
10558990
18045996
10925301
16280323
25581518
15899879
21441955
20566643
15466476
15657177
11706017
15059847
8444886
18519681
23528009
33513601
20138986
12368275
24608435
17062641
20082306
20375017
17537990
24567333
33820494
10712263
21278199
19011679
20145145
27582276
25640183
21730054
16177091
17250586
15879307
16728403
18299328
24269888
17303383
9482941
17671177
17173941
24095720
15304500
12874275
33828192
11827968
33731431
10799542
15328343
18838481
19036157
17634226
17110082
17855349
31722981
26079947
25002506
14559232
23584478
18593910
17114467
16373398
16931794
17016429
14676826
28415597
12029087
24269383
8626767
20478260
12097262
14764579
12181310
15100319
12384432
15271996
17562849
19036927
19326083
20072652
25940440
11922392
17913704
19494114
25596730
18938240
27449290
12897059
21478911
21123455
26804170
10940302
16624816
26876209
12048182
17150968
21478863
17307705
18658095
24995980
16582879
17289590
33667549
17209041
17890097
21726627
27662093
16843264
19426503
11103941
11940578
17906618
26234813
19029090
15007386
15958730
12576312
17667937
17785202
34480897
20647329
18941890
16446383
25562429
10867021
26985018
16413470
23178720
25578563
34437586
21738699
21258408
20388777
24681954
20459645
12242309
15289328
21575862
16185843
19147767
34497368
19153083
12124352
17371994
17567959
15611080
17297454
23012246
14557270
28542650
15713673
21129803
19460345
10958798
21772273
21900206
19205871
17591920
19217381
12963813
19718025
24469056
16624867
21149447
15728578
33902596
11971971
16455819
19112174
10751321
1835084
11016927
18267069
20410276
21980390
17409387
23831578
21477078
15558056
|
MAP2K1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
9694850
17081983
11319218
18799465
17389395
9447970
15342917
8226933
15851026
12270934
12644307
11242034
1381507
17906627
9677429
11986622
8376945
7992057
11948414
7687743
9731057
19197339
11704645
7565670
12750173
12932319
8626767
23331499
12048245
7559390
17272394
15811950
26987942
19494114
18669648
18691976
17192257
8388392
7898932
16464493
19369195
12920017
15466214
19690332
11134045
19534553
10995751
7867743
8223433
8248196
10567369
19933846
17563371
1518847
11730323
18983981
16186792
16135787
15951569
19058874
15212693
10748187
9560161
9925641
9733512
18083107
11104681
9006895
17569879
21071413
7731720
1330321
93330262
19541618
15466476
12925710
11971971
11136732
11118451
10746662
|
MAPK3
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9804779
20508164
23331499
24263804
18775330
10194762
12407017
8226933
17502367
34188118
9604935
18988627
31932645
8388392
12091337
|
MAPK3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
32205409
20150555
21983342
11904305
14593115
18199680
8226933
14744793
16079281
19318349
20882567
22266860
28574228
21097497
8388392
32615164
16377629
19245816
18775330
9604935
15212693
|
MAPK3
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
17018293
12134156
20506250
15547943
7816602
15084594
12697810
8226933
12738796
16393692
17255949
17439715
15187187
19541618
23109003
19565474
17722974
17052211
7588633
8545107
16055710
8388392
18039929
12972619
18775330
26725323
21098038
9604935
11274345
|
MAPK3
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10627507
10915800
18669648
|
MAPK3
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
20101026
14701740
26515730
|
MAPK3
|
GTF2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10648599
|
MAPK3
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
28115363
12801888
|
MAPK3
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
8798443
8960373
|
MAPK3
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
72.0
|
1.0
|
Omnipath
|
17081983
18767875
9731215
20230923
17693683
11135364
19413330
8314790
19664995
19415658
16083285
20068231
18452278
9712920
30628717
94064639
1737801
18491316
18669648
8144611
8245003
26505358
17287340
16094384
19033656
19651622
20058876
8376365
8325880
17924679
19162178
19664994
18707149
25692552
8125092
16964243
18212344
|
AKT1
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11154281
11715018
11923280
15169778
17680028
20214616
20398329
|
TP73
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20921405
15734740
20156675
10469568
11245471
10207051
|
AKT3
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
17646672
10217147
|
AKT2
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19216069
17680028
11756412
16680151
20214616
11463845
20452955
9829964
20398329
11504915
17646672
10217147
|
AKT1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
11756412
11923280
20856200
20452955
20398329
18332867
19664995
10217147
11154281
19216069
20214616
11463845
19166854
15527798
9829964
17570479
16680151
17646672
12145204
15169778
15140942
25241761
11715018
25209720
17680028
21930127
11504915
29311840
15574337
23397142
|
MDM2
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18499675
17700533
26025930
25417702
19218448
21088494
10321734
10469568
10435614
20588255
25301064
10207051
11223036
21261729
|
MDM2
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
69.0
|
1.0
|
Omnipath
|
17145710
10218570
17616658
16511560
22266850
12874296
21925390
25825738
21988832
25512388
16227609
22493164
22902369
25659040
18219319
12963717
15604276
18566590
12370303
19838211
26359458
27617579
25809483
34551723
10608892
23028042
22120712
25703327
12860999
32300648
16055726
24813712
17301054
12483531
23671280
17159902
27621617
25105592
20484049
20724842
27215386
10827196
26001071
11606419
23946421
19683495
20705607
24755078
25384516
20473904
12393902
|
MDM2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17974989
26411689
27835608
26973243
15640443
12145204
|
AKT1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16163388
18356162
16511560
|
NKX3-1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18360715
20363913
23492366
17202838
16697957
|
PLK3
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17804415
21296815
19690332
19413330
18650425
18669648
15302935
|
TP73
|
PMAIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17700533
20591651
20195489
20160496
|
AR
|
PMAIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20610535
17721441
16479009
|
STAT5A
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16398215
12024032
15626738
|
AURKA
|
RASSF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
22438769
17563743
19276349
|
AURKB
|
RASSF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19887622
19276349
|
GLI3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
Reactome
|
15198976
19852954
20360384
21878643
19684112
9874371
16651542
15115751
19955409
20154143
20487519
20014402
20956384
19818708
16740475
24072710
14528312
23955340
|
RBX1
|
TCEB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
16790436
32284348
24366543
15601839
19321346
17081101
23986495
15367669
15572695
9887101
17785452
15282312
|
RBX1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
RBX1
|
CISH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CISH
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
VHL
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
RBX1
|
TCEB2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
AKT1
|
RBX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
RBX1
|
NFE2L2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
RBX1
|
PDCD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
15703371
16697054
17053147
17884153
18931676
19270156
19622404
19686080
19797085
19809470
19847258
|
RBX1
|
CDC25B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
AKT1
|
RBX1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
MAPK8
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
29578371
17081983
19007248
23434668
21540183
22622703
17924679
18187866
24296261
18838864
19413330
20027304
21471201
19107194
16964243
18669648
15302935
|
SIRT1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21071413
23331499
17098745
|
YY1
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17530016
34589486
17431117
18778787
|
YY1
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10518827
16922677
10359895
17270283
|
AURKB
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23226345
|
TCEB2
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
CUL2
|
CISH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
CUL2
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
TCEB2
|
CUL2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
CUL2
|
VHL
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
CUL2
|
CISH
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
ADIPOR1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16622416
23762377
|
AKT1
|
APPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25241761
10490823
25814554
12621049
|
ADIPOQ
|
ADIPOR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21284979
12802337
16622416
|
ADIPOQ
|
ADIPOR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12802330
21284979
12802337
16622416
|
MYD88
|
SOCS3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
STAT5A
|
SOCS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17609438
10359822
19115200
12468433
21397011
12198248
11713228
15778369
|
CEBPA
|
SOCS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19332118
18212493
20351777
|
RBPJ
|
HEY2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11486044
11095750
11486045
17685488
12814948
11971902
11741889
|
HLA-DQA2
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD247
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
B2M
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
SMAD4
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
SMAD4
|
SP1
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
SMAD4
|
SP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
47.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013125
11013220
11074002
11114293
11279127
11283613
11283614
11376132
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21098712
21252118
21614932
2191300
22331441
22652804
23140366
23338822
23784029
23869868
25374926
8515656
9312026
9389648
9618481
9670020
|
SMAD4
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10823886
15183844
10887185
19032343
10839991
16442497
10753944
10843994
15128733
10559222
|
JUN
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10220381
9312063
9732876
|
SMAD4
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
9732876
10942775
|
MYD88
|
FLT3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
AXIN1
|
FRAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
10428961
16288291
16940750
19751508
22270359
8666229
|
AXIN1
|
FRAT1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
10428961
16288291
16940750
19751508
22270359
8666229
|
JUN
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
FOS
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
TNFRSF10B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
17439715
23430059
23850759
26587781
8545107
|
SP1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20148354
8355696
8892460
1406636
19437621
9054614
17502875
|
JUN
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
2513130
14561487
8617996
8934539
19255142
9217081
12760745
2498806
10521486
8597411
10858536
12392213
9819441
1380150
23562910
1944274
9867253
9571041
1900040
2511006
14684847
15467742
12231642
11950097
|
JUN
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11579103
12452838
10491186
17845581
9234684
7615560
8120390
17687519
7592673
16373364
|
JUN
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1527086
8670250
12475180
|
JUN
|
BTK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8683110
7915738
8468470
14764703
16365438
|
JUN
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17283040
10369069
17452336
18213731
12907627
14612525
23678002
|
MAPK9
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
17143273
17145710
17637567
12584171
20506250
11948398
15378002
16824735
9687508
8654373
20028971
12788955
9305638
15302935
26091349
33822843
18362184
17875713
16393692
9405416
17570479
1922387
18252863
25561726
7737130
10490605
17189706
11896587
34408980
11274345
20178741
8525045
16076903
7992057
19527717
7600582
17215518
8985011
11801649
19118012
11278395
8001819
8137421
19436832
16533805
8945519
12881422
9315636
10385525
12093796
14523011
19910486
15212693
8157646
12040039
11562357
|
AR
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11577103
11518798
9211894
8798722
16713569
9591784
17721441
|
FOS
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
20498278
16714286
21675959
25609649
23602568
9872330
20102225
8380166
18848838
18535250
2516828
8397339
15867431
18172215
9346889
10779323
9732876
16928824
26496610
15994313
22719067
24029232
16511568
20195357
11053448
20936779
26186194
18619508
20511396
16008525
10488148
21199371
8617242
17440114
16055710
15319445
11090181
9160889
23661758
1631061
15718494
11431474
31515488
8440710
7816143
20410304
34671206
|
MAPK10
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17143273
20506250
16824735
8654373
20028971
16007099
21988832
12167088
16393692
1922387
16076903
22327296
19527717
21757544
19436832
17670986
14523011
11274345
20395206
11562357
|
MAPK8
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
202.0
|
1.0
|
Omnipath
|
17143273
17804415
10617656
8846788
15958389
11948398
10882101
20028971
12697749
15894542
20514406
14612408
17875713
9891069
17570479
18922473
11809792
8586671
11896587
12185592
12871843
7992057
7600582
11278395
8137421
8001819
10493750
14557262
16549498
18707149
9169478
11460167
15289320
8157646
16007099
20506250
22110360
15378002
9687508
12740383
20732415
9305638
19270716
23331499
10747973
16291755
16393692
12832416
18988627
10713700
18669648
12087092
14633987
8525045
15677475
16076903
16166642
18650425
15590691
1608942
19910486
18212344
11562357
12228228
16740711
14701799
19690332
10871633
12531896
16713569
8654373
16983342
19664995
15302935
10962563
15068801
8621542
8607977
18362184
10393177
20068231
9808624
14572659
8224842
10585392
9407028
17363973
19527717
19436832
14517282
12407442
9487126
9692890
14523011
15212693
10908726
11108663
13130464
10064600
18429822
15299005
9774977
11907583
12963725
16824735
19413330
10617104
17055484
21071413
18452278
16434970
16157600
7737130
23816567
10987838
17189706
9561845
9575168
1460037
7652575
18617513
24113186
11971971
11801649
25098452
20058876
16533805
9184210
18003900
9315636
10385525
18957422
12881422
11274345
12052834
15749833
|
NDUFB2
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
NDUFS8
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFB9
|
NDUFA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
AIFM1
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFB9
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS8
|
NDUFA4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS7
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS8
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS7
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS8
|
NDUFB11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFB9
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS8
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFB2
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFB9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB9
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFB9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB9
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS8
|
NDUFB9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFB9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
AIFM1
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFS7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFS7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
NDUFS8
|
NDUFS7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
AIFM1
|
NDUFS8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
AIFM1
|
NDUFS8
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
AIFM1
|
NDUFS8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
15526035
16200211
16218961
16489074
17344420
20025615
20816094
24684389
|
TCEB2
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
TCEB2
|
CISH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
TCEB2
|
VHL
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
TCEB2
|
CISH
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17884153
18420585
18931676
19622404
19622774
19686080
19809470
19847258
|
NFE2L2
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24466341
17640564
18588981
15655294
22951256
|
NFE2L2
|
ABCC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18038766
17003472
14550278
23667609
19638449
|
IL15
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
SP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL21
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
12244150
16081783
16785506
24751819
|
SP1
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8107489
9819371
8407965
8981362
|
AKT2
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
14500571
23603750
12697749
11154276
27363949
|
AKT1
|
MAP3K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
16532036
14500571
11154276
30677014
17184578
|
MAP3K5
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
17634293
20348951
15247305
21785467
12194869
12221076
18818208
18029441
19667122
21726807
16760468
21212517
19749799
26147002
25310587
33573023
26375285
16648474
15944157
7839144
12456653
25915038
26853469
21856198
31575661
10521505
25702873
19029119
20156337
16928747
15020250
20452983
15242986
18570871
16845370
20871632
21040800
27203743
19783996
21931634
23608534
21697492
25619840
26964622
12758252
16632641
28881794
17210579
34048499
20921231
|
YWHAE
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
AKT1
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
MAPK8
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
7890696
15696159
15071501
|
YWHAB
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
SP1
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19716432
20971080
20179320
24458133
18068676
17449871
15462672
21696544
15330762
22511764
|
SP1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8864062
16928829
16704988
23662037
10773882
9353275
15661808
17984071
18430409
22347450
20739403
8994183
|
SP1
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18234965
7565762
10411657
23133566
10860921
9458366
17363581
7621073
8103518
10644769
|
SP1
|
TNFSF10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22415975
17047073
20150555
18701496
21603612
|
SP1
|
ITGA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8887648
20090957
11238113
11313353
|
SP1
|
HSPA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7553870
9060426
2674689
24669866
|
SP1
|
BTK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11254710
11779634
7721790
10362515
8562928
|
SP1
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20354117
14561739
15110170
18097593
20515942
|
SP1
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19129260
23475749
11416035
18443233
11072083
11779634
22282354
15507319
|
SP1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19145069
15342781
21520171
18353772
|
SP1
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17626239
10082538
9528985
|
SP1
|
CEBPD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17965828
9528783
20506344
17471507
|
MAPK8
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
28831131
22266860
18199680
19245816
25398907
17570479
|
SP1
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16713569
18068676
10224053
|
SP1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15737644
15710382
|
FOS
|
ITGA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
15067049
16393692
16394015
19667062
21385848
22634314
23418787
23430059
29556339
9064320
|
STAT5A
|
OSM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8605875
10428780
21457934
10556323
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
STAT5A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24218138
24469394
18042802
20385773
|
RET
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12600984
15994200
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
AKT1
|
EZH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
22391560
24526064
29864144
34230470
16224021
26517694
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
11756412
9705322
11923280
16697215
20398329
18372248
12865427
15071501
15808505
20138985
20214616
15883165
15169778
10949026
12861023
11715018
18636226
9812896
17680028
11956222
10722653
20832730
18570873
16376338
17052453
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
AKT1
|
PDCD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17053147
17081983
18296647
18187866
17287340
16357133
16964243
18669648
|
AKT1
|
AGAP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19176382
21460185
22450747
|
AKT1
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
GTF2I
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9584171
12082086
11934902
16611241
10082538
19097122
11313464
|
FOS
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15271374
12452838
17845581
16373364
|
AURKA
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15128871
22864622
20011137
22451695
12400006
19075565
19836940
16082213
|
MYB
|
PDCD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11470166
23606399
12082539
11313950
|
STAT5A
|
CISH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16125365
11696536
15769897
19036881
17001312
9129017
11713228
15778369
|
FLT3
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
19805105
21827948
9918857
19438505
31066629
11027663
|
CEBPA
|
SLC2A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18408001
23647459
20698834
16754198
12641495
|
YWHAZ
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
YWHAE
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
GNAI1
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
GNAI1
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9748257
23109003
15539636
7935349
16460834
11376933
|
CCNB1
|
CDC25B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
8119945
1836978
12754270
20360007
8440392
10827953
12411508
|
MAPK8
|
CDC25B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19638579
21807946
|
GLI3
|
PRKACB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17283082
16705181
20154143
16371461
16611981
|
NCOA4
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
12612084
17011702
12068007
15604093
15563469
10318905
11779876
10517667
11818501
8643607
11404460
9636157
9892017
16713569
10347167
|
MAPK8
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24424504
21512132
21820033
16282370
|
NFKBIB
|
FBXW11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
FBXW11
|
GLI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17053147
15340381
16611981
18813803
16651270
12820959
19797085
15071497
15688063
16371461
|
RET
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18669648
9312068
11062067
15911620
95141073
16153436
15755722
|
MAPK8
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
18985696
25862939
15696159
11956222
19788416
21081103
15071501
18559254
7890696
|
MAPK8
|
STMN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
30087586
20630875
|
DLL3
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16921404
29910816
22353464
|
NOTCH3
|
RBPJ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
12370315
11518718
11404076
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
TNFSF10
|
TNFRSF10B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
22266862
14585074
21459798
19427028
15538968
9325248
10894161
11239407
16189514
12628743
21525171
23678861
10549288
20103630
11094155
16227629
10542098
10894160
22585859
21822306
9242610
9311998
15766588
20097879
|
TNFRSF10A
|
TNFRSF10B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9430228
16319225
|
ARTN
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9883723
|
ALK
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12185581
23331499
|
GATA4
|
IL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9234684
9209438
7791790
7592673
16373364
|
TNFSF10
|
TNFRSF10A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9314565
9613612
14585074
19427028
15538968
9325248
10894161
11239407
16189514
12628743
10549288
20103630
10894160
9082980
9242610
9311998
15766588
9430226
|
BTK
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
11413148
17389395
17081983
7925280
16497976
11641791
17016520
8617237
|
BTK
|
GTF2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
17145710
15096481
9020138
20068231
11934902
9012831
11373296
14623887
10373551
9837922
16738337
11313464
|
MAPK10
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15071501
|
MAPK9
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17570479
15071501
|