Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HIST1H4A HIST2H4A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
THAP7 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 SET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23374587
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
UBTF POLR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21289084 17878937
RRN3 SET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17318177 5219672
TAF1B SET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17318177 5219672
THAP7 SET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
MK67I SET â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
TRI44 TAF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRI44 TAF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRI44 TAF1D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TRI44 TAF1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 TAF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 RRP8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 TAF1D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 TAF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 TAF1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZNF2 RRP8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RRP8 TAF1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RRP8 TAF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RRP8 TAF1D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZNF2 TAF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZNF2 TAF1D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EAF1 TAF1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EAF1 TAF1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EAF1 TAF1D â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EAF1 TAF1C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MK67I TAF1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 SRPK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 SET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
TAF1B THAP7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16195249 15561719
HIST1H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2AC HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2AC â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2AC HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
TAF1D TBP â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EP300 HIST2H2BE â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
HIST1H3A HIST1H4A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HIST2H3C KAT2B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
TAF1C P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10913176 16189514 16713569
TAF1B P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10913176 16713569
TAF1A P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10913176 16189514 16713569
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MK67I RRP8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 34079125
TAF1A TAF1D â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TAF1B TAF1D â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TAF1C TAF1D â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TAF1A TAF1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
P53 SRPK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21130767 32807901
HIST2H2AC HIST2H2BE â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TBP RXRA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7667283 16713569
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TAF1B TAF1C â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TAF1C TBP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
TAF1A TBP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
P53 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17545634 26556313 10766163 16713569 21761334
P53 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14976551 20075864 17827154 19011633 10521394 16697957 10777477 16107876 11099047 32494626 16959611 11313951 12426395 18765668 22266186 19303885 25241761 26539911 20633551
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
TBP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11595744 31527615 16713569 9259327
MECP2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14593184 12473678 16331260 14647463
TAF1D TAF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17318177 19615732 26186194 28514442
KAT2B P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20589832 17189186 16537920 14614455 12501250 10891493 17977830 9744860 19680552 10490106 15965232 9891054 16959611 16678111 12068014
TBP P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7799929 8083962 1465435 12379483 10601022 16713569 11313951 8395834 8405994 9349482 10359315
EP300 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29706626 25156994 12724314 23728348 16543236 12501250 9652736 9194564 18243116 9194565 19339993 16678111 16611888 11359905 11782467 12162806 14612423 14759370 15186775 15664194 9288740 23402884 17452980 24157709 9891054 12499368 19234109 27818144 16537920 17977830 15295102 10518217 16713569 26625199 16928824 11070080 17906639 23870121 23796514 15558054 17438265 25867071 17189186 18485870 11907332 15542844 19217391 32807901 16438982 31167125 15337767 10490106 22731250 12690203 25288747 18612383 23329847 24821727 26302407 9809062 16959611 22074660 19218448 16782091 23880760 33196849 25753752 28757384 18391200 16024799 25651062 16135789 22013068 11433299 9744860 10601022 21187340 11804596 23307557 10942770 15509808 20234175 21471221 26229107 19805293 22266186 15965232 23010591
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
SET TAF1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17318177 11163245 16189514
TAF1D TAF1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17318177 19615732 26186194 28514442
TAF1D TAF1C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17318177 19615732 26186194 28514442
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
HIST3H3 KAT2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
POLR1A RRN3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
TAF1C TAF1A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 16189514 16713569 7801123
TAF1B TAF1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17318177 26186194 16713569 28514442 7801123
TAF1C TAF1B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17318177 26186194 16713569 28514442 7801123
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
HIST1H3A KAT2B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186