Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ASH2L SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
BAG6 PELP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BAG6 CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HRAS CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199329
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
SENP3 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
TOM1L1 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
SMAD9 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A KANSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
EPAS1 KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
SUMO2 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19394292
KDM1A KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17707232
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
HRAS MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NPM1 EIF2AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219054 16957780
NPM1 KMT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
PELP1 NPM1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
NPM1 EIF2AK2 â—¼   COLOCALIZATION 2.0 0.8 intact 5219054 16957780
NPM1 SENP3 â—¼   COLOCALIZATION 2.0 0.8 intact 6541703 18259216
NPM1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12882984 16957780
SYK STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TCF7L2 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602747
STAT3 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15677471 23874455
STAT3 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23991099
STAT3 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22218594
TAF1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7724524 9242374
TAF1 TAF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22711989 16407123
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
TP53 RPL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21097889 22467867
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
WDR5 CHD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7542690 20085832
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
NR4A1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7664680 15950922
ESR2 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24914937 11457856
IGF1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19183465 12875741
AKT1 PHF20 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22334668 22975685
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
NR4A1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11274386 16835233
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
G3BP1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25784705 25520508
ESR1 BCAS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17505058 16617102
AR PRKD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 20813663
AR RCHY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16914734
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
SUMO2 RNF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TOM1L1 PELP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMAD9 PELP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PELP1 MDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21326211 8149485
SENP3 PELP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
ASH2L HIST1H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RPL11 TP53 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
LAS1L WDR18 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HIST1H4A RBBP5 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
BOP1 RRP1B â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
KAT8 PHF20 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 NPM â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29746960 16107701 33742100
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
CDK4 BAG6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 16169070
DOT1L NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20431927 26496610
EPAS1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23275444 15261140 22807441 25689462
WDR5 TAF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 32076268
TAF6 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14580349 23292512 22939629 26344197
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
WDR5 TAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 32076268
WDR5 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15960975 24930734
HDAC2 ZBTB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26949739 33301849
PELP1 IPO5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22190735 33961781
NOL9 IPO5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 BOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
ESR1 NPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 33731348 21182205 20348541
RL10 PELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
RS2 PELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IFIX PELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
IF16 PELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
IFIX SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
NOL9 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PHF19 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 LAS1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
IFIX LAS1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
IFIX TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
RL10 TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
PHF19 TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IF16 TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
NPM RL10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23402259 26496610
HIST1H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
H3F3A WDR5 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CSNK2A2 RNF2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HIST1H3A NPM1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HIST1H4A KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
PELP1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33742100 11481323
ESR1 KDM1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 17289570 31527615
PHF20 MCRS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
SENP3 RRP1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20926688 33961781 26511642
CCR5 STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11350939 14674010
TAF6 TAF9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23292512 7597030
CREBBP H3F3A â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CREBBP HIST1H4A â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
KAT8 HCFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16227571 20479123 24981860
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
KAT8 PHF20 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20479123 33961781 24981860
LAS1L WDR18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 33961781 26344197 24981860
LAS1L TEX10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 22939629 26344197
LAS1L NOL9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22190735 33961781 26344197 24981860
NPM TEX10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
RS2 TEX10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RB1 TAF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AR RCHY1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NR3C1 STAT3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KAT8 TP53 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
SRPK3 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
MDN1 TEX10 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CHD8 ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 20308527
DOT1L HIST1H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
H3F3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2AC â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CREBBP NR3C1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HIST1H3A RUVBL1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HIST1H4A RUVBL1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ESR1 ASH2L â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
SENP3 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19680224 15632193 22684029
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
HCFC1 MEN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
ESR1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
HCFC1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31076518 23508102 33961781 20305087 24981860 22939629 15199122
TAF4 TAF7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14580349 29111974 22939629 26344197
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
ESR1 RL10 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23403292 21182205 31527615
PELP1 SUMO2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19471022 21326211 19394292 32786267 21252943 16169070 21693764
ASH2L HCFC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
ANDR ASH2L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33640491 22722839
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
EP300 HIST2H2BE â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
MEN1 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 17050672 14992727 15199122
KAT8 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15960975 24981860
ESR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
WDR5 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
PELP1 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14963108 15466214 12415108
CHD8 WDR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ASH2L CHD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
ANDR KDM1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20228790 27085459 33640491 28611094 34585037
WDR5 MCRS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 24981860 27705803
CHD8 RBBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
ANDR TAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20181722 33640491
WDR5 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 28514442 27705803 33961781 24981860 26186194
WDR5 PHF20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 24981860 27705803
SENP3 SUMO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19394292 25027693 16608850 11029585
WDR18 PELP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8149485 21326211
PELP1 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22190735 33961781 24981860 26344197
PELP1 MDN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21326211 22939629
PELP1 LAS1L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21326211 20442285 22190735 24981860 22939629 26344197
PELP1 GCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26825173 12415108
TEX10 WDR18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21326211 33961781 26186194 26344197
TEX10 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197
WDR18 NOL9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
PRPF31 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LAS1L PELP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PELP1 WDR18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SENP3 WDR18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NOL9 PELP1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PELP1 SENP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
FBL RPS6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MCRS1 PHF20 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
LAS1L TEX10 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HIST2H2AC RNF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PELP1 TEX10 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GCR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23125313 12208951 17884810 31182584
WDR5 KANSL1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
SRC RL10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16741966 12138090
SRC ESR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12095943 12630920 15604093 11013076 11032808
AKT1 NR4A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11274386 16189514 16713569
PELP1 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14963108 21182205 11481323
ESR2 PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21182203 12415108
TEX10 PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 22190735 33961781 24981860 26344197
NPM PELP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 33961781 26186194
SENP3 TEX10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21326211 33961781 26344197
SENP3 WDR18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21326211 33961781 26186194 26344197
SRPK1 SRPK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23602568
HIST2H2AC HIST2H2BE â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
STAT3 SYK â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MEN1 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23508102 24981860 17050672 14992727 15199122
EP300 NR4A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21988832 12082103 16713569 20438716
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
WDR5 KAT8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 20479123 24981860 27705803
NFKB1 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8290595 7823959 16713569 16380507
HIST1H3A KMT2A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PELP1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15466214 16713569 12415108
NPM SENP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21326211 18259216 33961781
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NOL9 WDR18 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ASH2L WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31544921 17925232 16253997 20305087 21285357 15960975 21531708 15199122 17178841 25666610 16892064 15960974 18066051 23870121 23508102 21884981 32076268 33022573 22939629 16878130 31076518 27705803 19556245 17500065 19131338 33961781 24981860 16603732 26186194
ASH2L HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31076518 23870121 23508102 33961781 20305087 24981860 12670868 15199122
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
KDM1A HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 32882276 19703393 9804427 12032298 20164337 28667074 26949739 34031383 21258344 26344197 34050636 21670149 24981860 11102443 12493763 16079794 21937684
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
RRP1B NPM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20926688 33961781 19710015
GCR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26508788 9388192 16189514 16713569 25202013 14522952
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
ANDR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12804609 11322786 16713569 11751884
NFKB1 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12057007 25241761 16713569
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
STAT3 ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23295773 21546410
CREBBP STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649887 11773079
TAF4 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 14580349 31753913 11564872 26344197
TAF7 TAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29111974 22939629 16713569 7824954 31753913 11592977 18391197 14580349
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
KAT8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17189187 16601686
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
HCFC1 WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 27705803 24981860 20305087 22939629 12670868 15199122
WDR5 CHD8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 20085832 24705355 18378692
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
ANDR SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24728074 15062576 11032808 15466214 15027889
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
CCR5 CXCR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12429730 15660419 18632580
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
AKT1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18332867 28708672 16210317 11156376 11404460
NFKB1 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24296733 18425349
NFKB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22223884 10649441 10867646
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 PELP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19605405 15087130
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799378 20610535
SENP3 PELP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21326211 20442285 22190735 33961781 24981860 26344197
PELP1 WDR18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21326211 22190735 33961781 24981860 26186194 30021884 26344197
NR3C1 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21900206 23331499 15591535
KANSL1 KAT8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
KANSL1 PHF20 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BOP1 FBL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
TAF6 TAF7 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14580349 29111974 22939629
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CDK2 RB1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
INO80C RUVBL1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CDK4 RB1 â—¼   PHOSPHORYLATION ✅ - 0.93 0.93 Signor 9139732
RL10 RS2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 26344197 26496610
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
KAT8 WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RPL11 RPL26 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
RPL26 RPS2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP HIST1H3A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPL10 RPL26 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPL26 RPS6 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LAS1L NOL9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL10 RPS6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
TAF6 TAF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 29111974 22939629 7667268 31753913 12453419 14580349 26344197
RPL10 RPL11 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL10 RPS2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
TEX10 WDR18 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
KANSL1 WDR5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDK4 RB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL11 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 HIST1H1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RB1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
CDK2 RB1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CDK2 PELP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20807815
CDK2 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 32076484 26123729 17081983 27998958 16565220 19007248 19367720 23840880 12058066 19690332 22285574 25922180 21272329 19413330 20333249 24282781 32092641 27553022 19933848 19933706 16083285 18318008 20068231 24998852 23627734 26993766 18165222 17535915 18669648 24290756 17942908 81161106 18691976 11278991 19561638 17287340 16376875 18243139 19651622 17924679 18220336 24282525 19369195 15190079 25531824 18212344
CDK2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 77.0 1.0 Omnipath 26581405 9315635 17303408 18692063 23437375 19413330 20871633 26148348 28806746 15279786 16326706 8626527 21902831 14627988 7575488 9190208 21697511 9139732 20068231 17570479 16189514 12006580 11420722 18669648 15811853 18590585 27507850 17380128 23160093 19638577 1756735 20418918 19262748 17660363 11777937 10499802 19651622 20058876 15173007 22263797 10207050 8756624 10542199 19664994 24466208
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CSNK2A2 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 19415658 12082111 16565220 19007248 19691289 18669648 20166139 18691976 17081983 20230923 20068231 18452278 17570479 17287340 19413330 18510355 18212344
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CSNK2A2 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
SENP3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15632193 19680224
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TCF7L2 RUVBL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
STAT3 CXCR4 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
SYK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10777558 25416956 21516116 20133729 31515488 16189514 10825200 32296183
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
HDAC2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15653507 25241761
TAF1 TAF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF1 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RB1 TAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9242374 16713569 7724524 9858607 11126356
TAF1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28673515 15053879 20124405 16713569 29556568 24289924
TAF4 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF4 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF6 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
TP53 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12631625 18281476 18174288 21460853
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15540784 11791186 11504717
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
AR IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19318566 15033751 17202144 19250214 20610535
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
ESR1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19920132 17166846 22739988 10750020 11566442 20372799 8206951 9014838 24914937 11457856
AR IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24914937 8580999 17363459 22739988
IGF1 KLK3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 PHF20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22975685 22334668
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25581517 11274386 16223362 17570479 16713569 26155943 18669648
NR3C1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8639160 17016446
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
NFKB1 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11909978 15517885
NR3C1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 8290595 16380507 7823959
RB1 CDK4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CDK4 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 107.0 1.0 Omnipath 26203195 10498883 23336272 9315635 17303408 17363486 25803170 10359571 15081408 16236519 28249908 16936279 17478427 19690332 11520855 31615938 15279786 16326706 18981099 9190208 8626527 14627988 7575488 24417566 9003781 16360038 10385618 9736735 9139732 7736585 20068231 34158578 16189514 19075565 18669648 11773438 11641415 21880723 18590585 27708221 10962560 20068082 15489884 9425340 19225156 19551155 17045206 10210318 19262748 18786381 17660363 17621266 19651622 12657252 11746527 11254678 15809340 22263797 10202152 10778858 27811360 23981302 19664994 14676836 9380698 18583321 23429262 27430527
CDK4 PELP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20807815
AR FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14521927 21055159 20610535
KMT2A KAT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15960975
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
RCHY1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12200228 16713569 27903893 17721809 16914734
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
SENP3 SUMO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19394292 11029585