Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CAPN1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25969760 1730702
SP1 MPG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10563836
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
STK16 VHL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 17353931
SP1 RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742449
SP1 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11574690
DDX3X SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16818630 33627125
AR RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24119295 20610535
AR VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15805579 16425262
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
AR AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 23689136
AHR AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19815066 17392787
VDR MED1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20520624 20713445
KLK5 ST14 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 20657595 18843291
FLNC FLG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CELA2A KLK5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 20179351 17596512
PPARG SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18509005 24735796 20360975 22282354 18310298
ESR2 PI4KA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CAPN1 CAPNS1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
CAPN1 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
TP53 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16462763 16651407 18431400
TP53 DDX3X â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24180280 23584477 21325288
CUL2 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 22086907 28514442 9751722 10823831 15060148 11865071 21942715 27697924 20049704 26743088 11779168 17439941 12604794 9122164 21145461 15611064 19030229 21685897 12048197 10421634 28775317 15601820 10449727 24469044 11384984 10587522 18173839 22286099 17339318 16261165 16611863 23401859 15966899 22234250 9447969 17353931 26751167 18323857 25661653 33137104 11024059 18187417 18523483 10318914 26735018 24981860 33961781 31444342 26846855 17132228
MED1 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23178929 17704298 10944516 30575522 15604093 19596656 12037571 10037764 30595551 17011503 16554032 9325263 17468099 22070604 15026545 11500849 30651555 11027271 11877444 10935544
SP1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10919269 15664452 10845704
SP1 FURIN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8132667
FURIN FLG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11380615 15803139 16061697
MED1 ESR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 21182203 11867769 10770935
MED1 VDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12796488 10753860 12403843 10235266 17786964 21478865 10733574 16434701 9653119 10198638 12837248 15919092
ESR2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17088408 17556531
FLG ST14 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11380615 15803139 16061697
FLG PCSK6 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11380615 15803139 16061697
FLG PRSS8 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 11380615 15803139 16061697
MED1 VDR â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MED1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CAPN1 FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652
FLG CASP14 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652
LRRK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22924508 24113872 26123245 24165324 25977830 22303461
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
MED1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15848166 9444950 16713569 11118038
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
AR MED1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17483314 21593191 24778216 23887938
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
FLG KLK5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652
CAPNS1 FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652
CELA2A FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652