Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 UBAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GABARAP DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20639871
MAP1LC3B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBX1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
RB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SMAD2 RNF123 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF123 SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15231748
INSL6 UBAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LCMT2 UBAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REG4 UBAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMAD2 SMAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15231748
INSL3 UBAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
EMD LMNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17620012 34079125 12670476
RNF123 UBAC1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
LMNA TMPO â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21346760 32814053 25948554 11792809 31467278 34079125 19727227 24623722 30419336 21988832 22412018 26524528 26264872 29568061 16189514 29997244 30021884
UBAC1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RB1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
NFKB1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11473033 16317104 10022897 16784892 7528667 19628709 9733827 10871852
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
TP53 RNF123 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10562557 21422812 22085928 11593391
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368