Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PSMF1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRAP2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
RUSC1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CPSF7 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DVL2 PSMF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
WWP2 VASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BAG6 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WWP1 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATN1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
SMAD7 BMPR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 BMPR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
SMAD6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
FAM189A2 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CALCOCO2 SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CALCOCO2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CCT5 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
CLN6 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CPSF6 WWP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CPSF6 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CPSF7 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CTSD WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DIDO1 WWP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DIDO1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WDR5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 EGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19651900
WWP2 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WWP1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
WWP2 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRAP2 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HEXB WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SF1 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPUL1 WWP2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HNRNPUL1 SNRPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPUL1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
OPTN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11137014 5213395
RPS27A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCD1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
IGF2BP2 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 WDR5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12928483
WWP1 LAPTM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LITAF OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
SLC11A2 NDFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0904880106 19706893
SMARCD1 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
RNF11 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
WWP2 PDLIM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PDLIM7 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PEX1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 PSMF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PSMF1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PTEN RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10753747
UBE2D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
SMAD2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15599395 9812998
SEC24D WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
WWP2 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
SIRT1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16998810
UBC SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD3 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMARCD1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
TARDBP WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF4 TPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPP1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF4 UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF4 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBA1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22842904 21857666
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
WWP2 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
WFS1 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2J2 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WWP2 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WFS1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WIPF1 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PTEN USP7 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
RPB1 UBA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17996703
PTEN WWP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21532586 33470109 25547115
RPS27A WWP2 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
HNRNPL TARDBP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MYC RPS27A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC PDLI7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
UBB UBP7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27452404 12507430
UBP7 WWP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25071155 16713569
ATN1 EWS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16713569 24999758
EWS HNRL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29884807 21988832
SOX2 SMRD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
FIP1 WWP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31048545
MYC FIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
TMM51 WWP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MKNK2 BAG6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 26496610
BMI1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 20668194
BMI1 DIDO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CPSF7 WWP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31048545
LITAF UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC UBA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC TPP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RAC1 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RNF11 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 20676133
SPG20 WWP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25071155 19307600
UBB UBE2D1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBE2D1 UBTD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
WWP2 PDLI7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25071155 29892012 21516116 16713569 25416956 16189514 31048545
RU1C WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 32296183 31048545
EWS WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 31048545
EWS CPSF7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 24999758
HNRL1 WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 25071155 21516116 29892012 31048545
WWP2 SMRD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32296183 31048545
WWP2 FBX11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FA70A WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FA70A WWP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 31048545
CR001 SMAD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 WWP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 SMAD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TMM51 PDCD4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TMM51 WWP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WWP2 AMOL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25071155 26186194 28514442 31048545
WWP2 F168A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25071155 26186194 28514442 31048545
WWP2 AMOT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25071155 26186194 28514442 31048545
BMI1 XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34316702 24457600 20668194
PRPS1 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RNF11 WWP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28292929 15231748 32814053 31985874 16713569 16189514
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
SOX2 XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 21280222 23667531
WWP2 WDR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32296183 25071155 31048545
UBA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CUL1 UBB â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
POU5F1 WWP2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CPSF6 HNRNPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
SMAD7 WWP2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DVL2 WWP2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
UBP7 MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 27618649 29467282
WWP2 UB2L3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17719543 30207403 19274063 27295432 17996703 25723849 27182664 26949039
WWP2 SCNNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12167593 16713569
WWP2 SCNNG â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12167593 16713569
RPB1 WWP2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 17526739 31048545
PPM1G PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27880917 34079125
RAC1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11021801 16189514
RNF11 WWP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28292929 15231748 18724389 31985874 16713569 16189514
ARRDC3 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
PPM1G USP7 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
ARRD3 WWP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23236378 26490116 32296183 29416926
ARRD1 WWP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23236378 33961781 32296183 21191027 26186194 21516116 31048545 28514442 22315426
F1892 WWP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25416956 29892012 26186194 28514442
F1892 WWP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 34927784 25416956 29892012 28514442
WWP2 CPSF6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16713569 28514442 16189514 31048545
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
SMAD7 SMAD6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26555259 9256479
ARRDC3 OPTN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CALCOCO2 UBC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
WBP2 WWP2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CPSF6 CPSF7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBE2D3 WWP2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL1 UBE2D2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HTT OPTN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMAD3 UBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34580281 21988832 18729074
BMI1 UBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20601937 25605328 20800574
ARRD3 WWP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32296183 29416926 21191027 28514442
ARRD1 WWP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 32296183 21191027
ATN1 WWP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9647693 16713569
OPTN UBB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31723608 23414517 22101367
SMAD2 WWP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21258410 18729074
WBP1 WWP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26186194 16713569 28514442 9169421
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PTEN WWP2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ARRDC3 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BMI1 UBE2D3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
FBX11 CUL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 29103612 21145461 22113614 17098746 23319600
DVL2 WWP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26701932 31340145 34139860
RU1C EWS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10827180 29884807 16713569
WWP2 SCNNB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12167593 11244092 16713569
PTEN UBP7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31685992 29117568 24063548 24270891 18716620 26280536
UBP7 PPM1G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27880917 19615732 30367141 22361354 30804394
UBP7 TRAF4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23388826 11279055 31666375 16713569
SOX2 PO5F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12923055 23539445 25702638 19736317 30442713 26687479
PO5F1 WWP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19274063 22387393 29393344 19997087
AMOT AMOL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 19615732 24255178 24366813 34079125
ATN1 WDR5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26186194 16713569 27705803 28514442
WWP1 CPSF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 19447967 16713569 28514442 16189514
SMAD3 RUNX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10962029 10531362 21986102
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CDC34 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
UBA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
UBC WWP2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CUL1 RPS27A â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CUL1 FBXL15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
SCNNB SCNNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21775436 8986818 22526458 27903760
SCNNG SCNNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21775436 16423824 27903760 10409621
MYC RPB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29467282 17314511 12660246 23079660
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SNRPC EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10827180 16713569
SMAD2 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 11804592 28628118
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RHOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC S1PR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLC9A3R2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
WWP2 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19274063 22387393
S100A9 RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
STAT3 S100A9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24747959 18809714 22962574
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
SMAD6 WDR5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15498344 11737269 10748100
WWP2 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21258410 31546607 22773947
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
UBA1 UBE2E1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RPS27A UBE2D1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CDC34 UBA1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
UBA1 UBE2L3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
UBB WDR5 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBC WDR5 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ARRDC3 UBE2E3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
ARRDC3 UBE2E2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
UBE2L3 WWP2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
RNF11 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
UBE2L3 WWP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
EIF3A RPS27A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBA1 UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SCNN1B SCNN1G â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPS27A WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RPS27A UBE2D2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBA1 UBE2K â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
UBB UBE2K â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDC34 CUL1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
RPS27A UBE2K â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
RPS27A UBA1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBE2I UBE2K â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PAIP1 PABPC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 9548260 6547765
SCNN1A SCNN1G â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SCNN1A SCNN1B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PABPC1 PAIP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
OPTN UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDC34 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
UBC UBE2K â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11359933
CUL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15340381 15147722 12820959 12835716 11961546 11516665 15071497 15688063
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
PRKAA2 VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17082196 21945940
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
SF1 EWSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9660765 16713569
GRAP2 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
STAT3 POU5F1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19151334 20505821 15277698 18212089 17068183
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
RAC1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 26430964 16189514 11021801
WWP1 RNF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 15231748 18724389
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
STAT3 S100A9 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
SIRT1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21071413 23331499 17098745
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD6 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9256479 21071413 9892110
WWP1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15221015 15946939 15359284
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
WWP1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15221015
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368