GSK3A
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RPS15A
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RPS3A
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RPS3
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HTT
|
AP3B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSP90AA1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CHUK
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
XPO7
|
DDX19B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PRPSAP1
|
DDX19B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
EIF2B5
|
DYNC1H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
EEF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ELP3
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ETF1
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
ETF1
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
FLNA
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
FLNA
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
RPS3A
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HSP90AB1
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RPS15A
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
PKM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
RPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAP3K7
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219785
17363973
|
EIF4A1
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
EIF4A1
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
EIF4A1
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
GCN1L1
|
NAA25
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
RPS15A
|
RPS3A
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
ECM29
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22863883
26344197
|
ECM29
|
PSMD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
20682791
|
EEF2
|
ETF1
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
DYNC1H1
|
UBR4
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
PRMT3
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
PRKDC
|
TELO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ETF1
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
EP300
|
PRKDC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33742100
30110629
20808282
|
RPS3
|
RPS3A
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
RPS15A
|
RPS2
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
PSMB5
|
PSMG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
EIF4A1
|
EIF4A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
TELO2
|
PRKDC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18160036
20427287
20801936
|
ELP4
|
ELP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ELP5
|
ELP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IKBKB
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ABCE1
|
NAA15
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
IKBKB
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
PSMG1
|
PSMG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
TBK1
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10783893
21138416
|
PPP6C
|
MAP3K7
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
608155200
17079228
8204431
|
RPS2
|
RPS3
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
PSMG1
|
PSMG2
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
CHUK
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
RPS15A
|
RPS3
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
PSMD1
|
PSMD12
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
ABCE1
|
RPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
PSMD1
|
PSMD3
|
â—¼ CORRELATES
|
|
+
|
0.92
|
0.92
|
CCLE
|
31978347
|
PSMD12
|
PSMD3
|
â—¼ CORRELATES
|
|
+
|
0.92
|
0.92
|
CCLE
|
31978347
|
RPS2
|
RPS3A
|
â—¼ CORRELATES
|
|
+
|
0.93
|
0.93
|
CCLE
|
31978347
|
MAP3K14
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
16498412
5218365
|
ABCE1
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
EEF2
|
RPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ABCE1
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ABCE1
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ABCE1
|
ETF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
NFKBIA
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.97
|
0.97
|
mint
|
8209688
16126728
506093200
|
ELP3
|
ELP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ELP4
|
IKBKAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ELP2
|
ELP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
EEF2
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
PSMB5
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
RPS15A
|
RPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
PSMB5
|
PSMD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
EEF2
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
EEF2
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
ELP2
|
ELP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ELP2
|
IKBKAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMB5
|
PSMC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RPS2
|
RPS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RPS3
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ELP3
|
IKBKAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
EIF2B4
|
EIF2B5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD1
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RPS15A
|
RPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPS15A
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD1
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RPS2
|
RPS3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GSK3A
|
EIF2B5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
19651622
19007248
17081983
20166139
9468292
18691976
18088087
11500362
19664994
20068231
18452278
18707149
12133000
16097034
19413330
18669648
15302935
|
FLNA
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
10679398
15536066
16849481
17237376
21277899
21807870
27242793
|
MAP3K7
|
MAP3K14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
10094049
|
MAP3K14
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17145710
11278268
10195894
9520446
14743216
9689078
9346485
16285893
10733566
10779355
10072079
11460167
10022904
10713178
|
MAP3K14
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
69.0
|
1.0
|
Omnipath
|
17145710
11278268
16498412
30833792
23915189
9346485
11520989
10072079
17563756
18515365
10887201
16223731
12556537
16286467
14743216
9244310
20348096
10094049
15140882
15208311
20685151
25241761
9742107
10229185
9520446
15084608
15994789
10713178
9819420
17150968
11239468
16691505
26948423
20651737
9020361
|
CHUK
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
MAP3K7
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
14960582
16893890
15836773
33895773
12547194
25241761
24911653
2547194
9742107
18949366
11274345
20200282
20194509
10094049
18855897
10187861
|
CHUK
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
113.0
|
1.0
|
Omnipath
|
17145710
15922746
11087742
18074035
12626540
11527961
9244310
11809792
15836773
16177806
9721103
18501560
11923072
17706453
9509763
10723801
11858955
10421793
25133483
10398585
9346484
9346241
21765415
8657102
16737960
9315679
9252186
21490922
16219905
14743216
20484017
10329646
18922877
10882136
16153868
10195894
14751757
16007147
7796813
17053167
9632633
15856023
17965022
10783893
10602462
23602409
27682876
10469655
16965765
15084594
16493072
11095741
12138192
10723127
15210742
10329681
7878466
26930276
9914500
9520446
12514169
12403772
10527519
15145317
16493424
9135156
16023083
12637324
10593898
14636585
9214631
7862124
10074115
15389589
12486103
9891086
8601309
10880512
7739562
16286467
17379600
23109003
9689078
15371334
10733566
29145629
11042193
23970940
10085062
17468758
|
CHUK
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
9346484
24911653
20932476
28514442
11971985
16970925
12210728
9346485
17965022
16713569
12486103
9891086
15456791
11057907
20434986
16129692
16260493
21903422
21724995
16286467
14743216
16319058
18949366
10779355
25748427
25852190
12244103
11585904
9751060
15218526
10094049
10837071
9914500
21575199
9721103
25241761
10195894
9689078
15214841
21784860
17561400
21640763
16285893
10733566
16186825
16493424
10022904
12709429
12351658
10968790
12547194
15691841
15620648
15327770
11864612
11460167
14636585
17693255
17072322
9346241
|
IKBKB
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
IKBKB
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
TBK1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10783893
21903422
21138416
10195894
14743216
16207722
10022904
14560022
|
MAP3K7
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
24911653
11129660
25195736
16006187
16260493
15502405
14530355
10779355
28159912
10094049
10837071
15836773
25659581
10195894
9689078
17363973
10807933
15214841
16186825
16493424
10022904
18316610
10187861
12547194
33895773
28475177
16301747
15691841
15620648
15327770
29748387
19632174
11460167
17965022
|
IKBKB
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
164.0
|
1.0
|
Omnipath
|
18593939
17145710
18375836
11087742
16793322
11527961
28086098
21232017
12429743
21423167
17693123
21399639
15836773
16177806
9721103
29139553
9271416
17561400
11923072
10889159
17706453
10723801
12791687
11858955
22037600
16365431
10421793
25133483
10398585
9346484
9346241
11158290
18539148
23328071
15574499
21765415
16818647
8657102
18202307
16737960
9315679
21490922
9252186
20001801
15919917
16495515
11368781
16291755
24386391
14743216
25759022
10329646
10882136
16153868
10195894
14751757
18981174
10807933
16007147
7796813
9632633
15856023
17965022
25753787
10783893
10602462
27682876
16965765
15084594
19196987
17322026
12138192
10723127
15210742
16319058
15217903
15218526
7878466
9914500
17367806
9520446
15214841
16846590
12514169
18657515
12403772
10527519
15145317
16888014
16493424
17047224
9135156
15024091
16023083
10593898
14636585
22579987
9214631
24911653
7862124
10320352
16970925
23707515
9346485
12949498
17363905
12486103
9891086
8601309
10880512
7739562
16286467
23109003
9689078
25595906
15371334
16285893
11356195
29145629
23970940
10085062
11815618
17468758
17615396
24586253
17072322
|
PPP6C
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17079228
|
MAP3K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15692051
17947236
11865055
17965022
17186025
|
PRKDC
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11749722
16319174
|
TBK1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
10783893
9721103
16007147
12138192
7796813
12403772
10990461
10421793
11815618
8657102
10398585
8601309
|
PRKDC
|
PRKDC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.22
|
4.21
|
PKG
|
28854368
|