Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MTA1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24424621 18719363
SNCA AP3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
ARRB2 NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
BRAF MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16888650 5218924
BRAF MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16810323 5218785
PEBP1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10490027
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
CCNB1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GATA3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189993
CTBP1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21681822
NCK1 CKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HNRNPL CSE1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ CSE1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRMT5 CTDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15670829 5217489
POLR2B CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15670829
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR2E DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EEF2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
NCK1 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YWHAZ EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
EXOC4 EXOC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 23037926
SNCA EXOC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
NOTCH1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15356142 17658279
SP1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15486968
YWHAZ GDI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
GDI2 RAB5A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GTF2F2 POLR2E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11278533
NOTCH1 HEY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21828089 14976548
YWHAZ HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
HNRNPA2B1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AB1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSP90AB1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LCK MED28 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16899217 6731769
LCK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
USP9X MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STK38 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17906693
STK38 MAP3K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17906693
RASSF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18566590
MED28 YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033846 16964398
STK24 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
YWHAZ MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SP1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAF1 POLR2E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STK38 PANX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22445341
SP1 PEBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24386147 9105667
YWHAB PI4KB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STK38 PI4KB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22445341
YWHAB PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRMT5 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRMT5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STK38 RAB11FIP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22445341
RICTOR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19720745 8009237
SP1 SF3A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SF3A1 WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3A1 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3A1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SF3B5 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SFPQ TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAB STK38 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STK38 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STK38 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25601544
YWHAB WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
WDR77 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ WTAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
XPO1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ERH WTAP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 14499342
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EXOC1 EXOC5 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EXOC4 EXOC5 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA1 HNRNPA2B1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB WTAP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ERH HNRNPC â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPC PAF1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CHERP HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ERH SAFB â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CPSF4 SF3A1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CHERP SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ERH SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
YWHAB MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
SNRNP40 WTAP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA2B1 SNRNP40 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC WTAP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GCN1L1 NAA25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
COPA SF3A1 â—¼   CORRELATES - -0.82 0.81 CCLE 31978347
HNRNPA2B1 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PAF1 POLR2B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
MALD2 STK38 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARRB2 NAA15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
EXOC1 VPS53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBM34 RBM28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STK4 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23386615 26673895
SF3A1 SF3B5 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA2B1 SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
USP9X YAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CHERP SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SAFB â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SFPQ WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 HNRNPC â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SF3A1 WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CHERP SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPL WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
ERH HNRNPA2B1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SAP18 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AGO3 AP3M1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AGO3 AP3B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AGO3 AP3D1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK8 CTDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19914168 26496610
EHMT2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 17967884 16702210 26186194 28514442 31041561
MOB1B MOB1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
STK38 MOB1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25852190 20624913 15197186
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
EXOC2 EXOC5 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SAP18 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
EIF4A3 SNRNP40 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CAV1 CAV2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CPSF4 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SAFB SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA2B1 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
PAF1 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CPSF4 HNRNPA1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA2B1 SAP18 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ERH HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
YWHAB YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 8008024 17974916 1602907
ACTR10 DCTN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR2 CTTN â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HNRNPC SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
VPS51 VPS53 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA1 SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ERH SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
BECN1 XPO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26673895 11309306 16713569
CAV2 NCK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091389 16189514
CRK NCK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9837978 8879209
SAFB SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CTDP1 POLR2E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPA1 SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPC SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA1 SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
MTOR MAPKAP1 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 21045808 8088164
S100B MDM2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17010455 20591429
GTF2F1 GTF2F2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
YAP1 YWHAB â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
SAP18 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SFPQ SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SAFB SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HNRNPC HNRNPL â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
CDK19 MED28 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK8 MED28 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EXOC1 EXOC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435
EXOC1 EXOC4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
STK4 MAP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 24366813 20562859
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HNRNPA1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPL â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CDK19 CDK8 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
HNRNPA1 HNRNPC â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CALM1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CPSF4 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
SF3A1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HNRNPA2B1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ARRB1 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPL SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPC SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HNRNPC SF3A1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EGFR PDCD6IP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPC SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ACTR10 ACTR1A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
COPG1 COPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 14729954 26344197 22939629 28514442 9751720
NOTCH1 FBXW7 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 23022380
GATA3 HDAC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29453984 26028330 31409898
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
LCK MED28 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10656681 16899217
STK3 MAP1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23455922 32707033 24366813
STK4 MOB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 22863277
TBK1 NCK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 7706279
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SF3A1 SNRNP40 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EGFR NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HNRNPA2B1 HNRNPL â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EXOC2 EXOC4 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
YWHAB BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
HDAC2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967884 11022042 18212045 16713569 10766745 28947780 31041561 16036112
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EXOC1 EXOC2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
STK3 MOB1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23972470 31941533 24255178 18362890
STK3 MOB1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 24255178 19919647
TRAF3 TBK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22792062 32779804 20174559 22908223 19380580 33187908 24763515 24622840 27135603 23308279 29125880 22079989 33411856 33372174 34084167 32324863 33608556 31404116 23717208 23986588 28049150 26928339 29920243 17991829 22330071
CALM1 SNCA â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
EXOC1 EXOC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
VPS51 VPS53 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AP3B1 AP3M1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ARF3 PI4KB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9148941 10559940 17555535
STK38 AAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22445341
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
CAV2 CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9361015 31980649 18081315 12414992 24013648 10212252 16189514
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
EGFR CAV2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 25402006 16799092 15273741
MED28 CDK8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26496610 26186194 29568061 28514442 23602568 15175163
CDK8 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15546612
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
PRKAA1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23291169
CTTN YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 093880 8009870 20363754
NCK1 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 9362449 16273093 25402006 1333047 10026169 8662998
GATA3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
EXOC4 EXOC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 17043677 31413325 90000000 19889837 28514442 19885391
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
GATA3 WTAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
LCK MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24863062 15735648
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAP3K2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11343802 23331499
MAPK3 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
PRKAA1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14970221
STK38 RAB3IP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22445341
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
STK4 STK38 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19062280 24747552
TRIM25 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
TRAF3 TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
EXOC1 EXOC2 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTR1A DYNC1H1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ACTR10 DCTN1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
STK4 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 21808241
CAB39 STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ACTR2 ARPC4 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
YWHAZ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217040 15161933
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
COPA COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
ETF1 SMG1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RASSF1 STK3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
TBK1 TRAF3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
MOB1A STK4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
COPB1 COPB2 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CTDP1 POLR2B â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SF3A1 SF3B5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
FBXW7 NOTCH1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
COPB2 COPA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9482852 14729954 10921873 26344197 22939629 8940050 8537409 22863883 9751720
COPA COPB2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CTDP1 GTF2F2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
MDM2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18544533 21081496 19879840 29676828 21857681 12538596 15878855 21466165 11588219
EXOC4 EXOC2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 27173435 22939629 21241894 26344197
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPA COPG1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BRAF YWHAZ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
GTF2F1 POLR2B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
GTF2F1 POLR2E â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EXOC2 EXOC4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DCTN1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EXOC2 EXOC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EXOC4 EXOC5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MAPK14 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPB1 COPB2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTDP1 GTF2F1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF4A3 SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAPKAP1 MTOR â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
BRAF MAP2K1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPA COPB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAPKAP1 RICTOR â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2F2 POLR2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2F2 POLR2E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2F1 GTF2F2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EXOSC1 EXOSC2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
POLR2B POLR2E â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
ARRB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15878855 23331499 21081496 12538596 17303558 11588219 21466165 18544533 21857681 19879840
MAP2K1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28169830 11226259
MAPK14 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
BRAF YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 17353931 8668348 15324660 15161933
BRAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 20212043 7706312 25437913 9560161 7936666 14970219 18567582 18332145 8413257 23331499 15342917 21071413 7731720 7873542 26496610 10976102 18988627 17667937 16255777 8131746 16888650 15485920 8394352 15175348 15466476 19541618 25600339 25155755 17563371 16810323 8157000 17979178 18039929 94178255 23934108 7835430 7624324 24746704 16135787 7935374 8039496 8621729
BRAF YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12620389 17353931 24255178 15324660 10931830
EGFR CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17145710 19901323 20029029 12359306 16497976 25402006 17389395 18578522 16799092 20068231 3415247 7925415 18669648 12153558 24658140 17287340 14960328 18707149 17016520
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
SP1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15737644 15710382
HDAC2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15169839 17615296 25241761 22796940 20818389 21685935 15388328 20519943 12508111 11309385 17018611 22514743 19597490 14673164
CTBP1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15169839 17615296 21416054 22796940 20818389 21685935 22370643 20519943 12508111 17508028 11309385 19597490 14673164
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
GTF2F1 CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12732728 12591939 9765293
MAPK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10537323 17081983 18088087 15144186 21079800 16964243 20444238
DNM2 SH3GL3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16732277 16339507 25748042 17088212 29559111 17088211 9808461
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
PDCD6IP EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 31980649 15456872 12771190 24658140 15557335 25402006
MAPK14 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15187187 18039929 19138820 7535770 12738796 17139251 16932740 23397142 16785992 11274345
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1333047 23331499 31980649 10026169 16273093 9362449 8662998 24658140 25402006 15951569 9843575
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
FBXW7 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11425854 11461910 20571051 23331499 20823234 17909182 25344755 32792479 11585921 16713569 17646408 27229929 15546612
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
GDI1 RAB3IP â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 17574030 8408203 27246931 20308558 20937701 21216617 22433857 21041651 24296415 22983554 17208202 18701652 22653444 25341920 12221131 22365832 17646400 21273506
GDI2 RAB3IP â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 17574030 8408203 27246931 20308558 20937701 21216617 22433857 21041651 24296415 22983554 17208202 18701652 22653444 25341920 12221131 22365832 17646400 21273506
SP1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11255234 19339281 10421804 18513187 16652385 19679555 22549838
MAPK3 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 9535909 19664994 9535905 12637502 15605363 8631994 17570479
MAPK7 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9535909 19664994 9535905 19701097 12637502 16189514 8631994
GTF2F1 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
GTF2F2 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7854423 11278533 31467278 11183778 8441635 16189514 8662660 7827505
HNRNPA1 GTF2F2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
GTF2F2 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
ISG15 HERC5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16407192 17289916 16815975 16352599
NOTCH1 HEY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11486044 11486045 10964718 12814948 14739937 20007915 11971902 21956839
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
LCK MED28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 16899217 10656681
LCK NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14583609 23331499 16713569
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
PEBP1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10757792 10490027
MAP3K1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8385802 12048245 8131746 17110930 8034665 8019005 10969079 12456688
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
MAPK14 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 21675959 16456544 23602568 17395714 21988832 10581204 23331499 21071413 27898710 23047924 10922375 12738796 11551945 26496610 25852190 18988627 15629715 18669648 15187187 11042204 26186194 25241761 8846784 17906627 14499342 9922370 7923353 9768359 18039929 25255283 7592979 17255097 11274345 23455922
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15649893 16648474 11997522 10747897 18347059 17255949 11274345 12697810
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15657420
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
RICTOR MAPKAP1 â—¼   PHYSICAL_INTERACTION 45.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 15718470 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19203586 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 22475393 22924465 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR MAPKAP1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR MAPKAP1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RICTOR MAPKAP1 â—¼   SHARES_COMPLEX 45.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 15718470 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19203586 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 22475393 22924465 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MAPKAPK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19738896 15688025
MAPKAPK2 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9705322 16376338 11956222 12861023
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK4 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24255178 23386615 23431053 21808241 18328708
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
RASSF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17379520 24366813 26186194 14729613 22195963 24255178 20920251 21808241 21199877 19962312 20086174 32296183 17598981 29063833 18347058 17889669 23455922
STK24 STK38 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12493777 16314523 21262772
TRAF3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27135603 15210743 16127453 15210742 16306936 12702806 23986588 22792062 16177806 20389019 17991829 20174559 16858409 23717208 34084167 22330071 17468758 17327220 24622840
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368