GSK3B
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
GSK3B
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
GSK3B
|
GLI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16481469
23331499
|
YWHAZ
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
ACTN4
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
AXIN2
|
PLK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0604206103
16815967
|
CTNNB1
|
BTRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15473860
10882123
|
MAP3K3
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AA1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CHUK
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CORO1C
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CTNNB1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CTNNB1
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8383887
22234184
|
GLI1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19329935
19930158
|
YWHAG
|
ERC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
IKBKG
|
FLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
FLNA
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
FLNA
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
FLNA
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FLNA
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
FLNA
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
FLNA
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
SRC
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16844778
0604705103
|
YWHAZ
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AA1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAZ
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AB1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
HSP90AB1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IKBKB
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219779
17363905
|
IKBKB
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAZ
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IKBKG
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MAP3K3
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
SQSTM1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16874300
|
WWTR1
|
LATS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21205866
18227151
|
LATS2
|
YAP1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.8
|
0.8
|
Signor
|
22658639
|
MAPK1
|
MAP2K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
23241949
8412360
|
MAPK1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16709866
|
PAK1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10385525
10791986
|
MAP3K3
|
MAP2K5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MAP2K6
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11460167
10882101
|
SFN
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15778465
5217604
|
MAP3K2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20588253
7996770
|
MAP3K2
|
YWHAE
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
9452471
5221876
|
WNK1
|
MAP3K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14681216
|
STK38
|
MAP3K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17906693
|
MAP3K2
|
PKN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12640115
10818102
|
STUB1
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SUGT1
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAE
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAZ
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAQ
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAG
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAH
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRAF7
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAB
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRAF7
|
MAP3K3
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
WNK1
|
MAP3K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14681216
|
SRC
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
YWHAB
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
SFN
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15778465
5217604
|
YWHAG
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
YWHAZ
|
MCM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
MCM3
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKB1
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9762895
|
NFKBIA
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219675
17318178
|
PLK1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7996327
20869364
|
PAK1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
UBC
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6504434
17936276
|
STAMBP
|
UBC
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
YWHAB
|
STK38
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
STK38
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
STK38
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25601544
|
UBC
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
UBC
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
UBC
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
USP2
|
UBC
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
YWHAZ
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213315
11118213
|
YWHAQ
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12535517
5216053
|
YWHAG
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
YWHAB
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
YWHAB
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217174
15324660
|
UBC
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5216530
12857745
|
MARK3
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
NFKBIA
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
LATS1
|
YAP1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
22658639
|
YAP1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24976009
29789528
|
AXIN1
|
AXIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20128690
22682247
|
YWHAG
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
5217174
15324660
|
HSP90AA1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
SFN
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
UBC
|
XIAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.82
|
STRING
|
36370105
|
BTRC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
AXIN2
|
CTNNB1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
11940574
|
IKBKB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
NFKBIA
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.84
|
0.84
|
mint
|
8209688
16126728
506093200
|
IKBKG
|
NFKBIA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.84
|
0.84
|
mint
|
8209688
16126728
506093200
|
YWHAZ
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
5217040
15161933
|
YWHAB
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
8008024
17974916
1602907
|
GSK3B
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
16293724
|
MARK3
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
IKBKB
|
NFKB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
11158290
|
GSK3B
|
MAP2K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
LATS2
|
LATS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
24255178
21233212
32707033
34079125
|
BTRC
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.85
|
STRING
|
36370105
|
YAP1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24976009
29789528
|
WWTR1
|
LATS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22078877
21555462
29787761
20412773
27847303
26116754
|
SRC
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12215529
16374509
|
YAP1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
YAP1
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
BIRC2
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BTRC
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
AXIN1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BTRC
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
MAP2K4
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
BIRC2
|
XIAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
YWHAE
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
YWHAE
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
YAP1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
22234184
8383887
|
YWHAB
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAG
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAG
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
YWHAH
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
BTRC
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BTRC
|
CTNNB1
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.88
|
0.88
|
Signor
|
10228155
|
CTNNB1
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
MARK3
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
LATS1
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
MARK3
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
YWHAE
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
NFKB1
|
BIRC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
21725609
23178297
23572150
|
YAP1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CAMK2B
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24117889
|
MAP3K2
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10085062
14636585
|
YAP1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23607968
22234184
23245941
|
YWHAE
|
GLI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8009500
038232
19996099
|
IKBKG
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
8209688
506093200
16126728
|
YAP1
|
LATS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27325643
29891922
28416659
27847303
32292505
17889669
30472188
33141042
18413746
22641346
26933062
18640976
24255178
27684187
22863277
24107629
30266805
31619268
21041411
21383157
30461308
24366813
20841485
28754671
25751139
25796446
27886176
25283809
18158288
34079125
|
YAP1
|
LATS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17974916
21832154
21205866
|
RAP1A
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
MAPK1
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAP3K2
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11343802
23331499
|
MAP2K2
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
MAPK1
|
MAP2K2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K7
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP3K2
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14636585
10085062
|
MAP3K3
|
MAPK1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
16407301
509249200
8007293
|
MAP3K3
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14636585
10085062
|
MAPK1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
MAPK1
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
PLK1
|
SUGT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21864708
22869522
|
YWHAG
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15778465
15324660
|
YWHAZ
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23840115
15161933
|
SFN
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23840115
15161933
|
SFN
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15778465
15324660
|
YWHAG
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
YWHAB
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
YWHAZ
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
20618440
7899808
|
HSP90AA1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
AXIN2
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
BTRC
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
YAP1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
SQSTM1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
STAMBP
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
CTNNB1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
5218183
16376880
|
YWHAZ
|
MARK3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
5217040
15161933
|
IKBKG
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
UBC
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CTNNB1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5219694
17318191
|
PAK1
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
23455922
32707033
31980649
|
MAP2K5
|
MAPK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
IKBKB
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CHUK
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
BIRC2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
HSP90AB1
|
SUGT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
CTNNB1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
AXIN2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
NFKBIA
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.97
|
0.97
|
mint
|
8209688
16126728
506093200
|
MAP2K7
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
MAP2K1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
GSK3B
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.98
|
0.98
|
mint
|
8209688
16126728
506093200
|
LATS1
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
MAP2K5
|
MAP3K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
MAP2K5
|
MAP3K3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
MAP2K2
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
NFKB1
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
UBC
|
USP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
HSP90AA1
|
SUGT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
LATS2
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PARK2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
IKBKG
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
NFKBIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BTRC
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAP2K1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17081983
21105670
16964243
14617795
30711629
18547980
8382613
17188038
17192257
15020233
|
AXIN2
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15611123
10966653
10911903
888800000547
9554852
22745173
9566905
22322943
|
MAPK1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16039586
28646232
18451303
|
GSK3B
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
26999213
12871932
11425860
24618402
18669648
17693123
|
GSK3B
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
20128690
16944320
11738041
20043192
12511557
11967263
16890161
22613765
14663202
23602568
8524413
24451375
19303846
12554650
8638126
22509369
18593713
16199882
21988832
23331499
19759537
10428961
9482734
22270359
19202075
17570479
16293724
15327768
10581160
17318191
11487578
22773187
26496610
16568235
17318175
19131971
15465828
26912724
25241761
24976009
21242974
22682247
10228155
23579495
12584189
23959799
15020233
10421629
10488109
11278246
9501208
18632848
10481074
10535959
10318824
9554852
17601533
9832503
21502811
9734785
23455922
|
GSK3B
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
183.0
|
1.0
|
Omnipath
|
22415718
11967263
27158593
29455668
19303846
19797085
8638126
19293931
23056571
22662165
25352148
16611981
27068260
28337019
10671551
21743491
20688898
16293724
23721711
23552738
18687691
28977889
19622173
12051714
25241761
27683053
28549350
22699938
19565571
23076981
21562161
19575820
20219694
20537194
10330181
21986938
29183346
27773936
11251183
19711366
21035499
19675674
7542250
23151663
24451375
14663202
23804296
8524413
25639486
23770025
18070361
26892600
30143633
9233789
19667122
27507058
19061640
19223551
29387014
23331499
16199882
11533658
18644116
24501426
24913829
11835406
17318191
26014148
25366337
28183999
22640743
26910375
12000790
12114015
18387957
19107203
9832503
16371461
29805709
27462866
20137080
27902311
12040186
19576224
25644994
12615961
19060929
25897075
12851486
15465828
17053159
18952601
10228155
15020233
17444818
20140245
26453498
17052453
16944320
24015932
23602568
24975844
24931005
28948000
20080742
23209942
30271168
28220106
16520547
28430641
11818547
25546293
27672271
11955436
11154277
26373837
16039586
23778311
28697793
20302655
25136145
26905812
22216350
8666229
12957350
23109003
10074433
28529629
20215423
21329734
11254732
9501208
27098453
27281614
30279527
19631635
25482131
18455992
24403311
11274345
|
CHUK
|
AXIN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
12799363
23430059
7542250
8666229
|
AXIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
20128690
20531388
16890161
27902311
22509369
18593713
16199882
23331499
9482734
21071413
26496610
19244247
22773187
17318191
10196136
18988627
17208333
19131971
24976009
22682247
10228155
12805222
12000790
10488109
9501208
9601641
18632848
9554852
19166851
23959799
12421363
9734785
11940574
|
CTNNB1
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24447505
15473860
11809809
22615875
11809808
12711682
11940574
|
CTNNB1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10966653
19751508
7542250
8666229
17143292
11955436
11967263
23343194
22270359
9554852
22699938
16039586
16940750
9566905
19619488
15766563
12051714
|
NFKB1
|
BIRC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15050749
17673602
12687011
15756023
9733516
12010810
18566231
16453001
20103608
|
BIRC2
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19223549
12867425
20301198
|
BIRC2
|
ERC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21872579
16497931
|
CHUK
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
BTRC
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20048001
23431053
24976009
21900206
|
BTRC
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
46.0
|
1.0
|
Omnipath
|
11850407
27001857
20638939
10075690
25190485
10497169
25900982
9859996
10338206
24912152
20797629
22590978
10437795
20353940
9990853
20558726
16189514
12482991
19053519
10713156
22022389
10066435
22388891
24464578
9990852
10072378
11027288
10644755
20851351
19933270
17319651
11158290
|
BTRC
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12482991
10835356
11158290
11953428
|
BTRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
23514615
17053147
22912335
17145710
27001857
20531388
18851830
12820959
24451375
18805092
25900982
11818547
16798748
19061640
19956254
23331499
24912152
19150432
22017875
24501426
28018973
16376880
21466614
27316454
19053519
26506240
14516475
25149538
10023660
22682247
10228155
9461217
24464578
18354482
26091241
10074433
12114015
9990852
14706645
18650423
25873176
19966869
25515538
20851351
22730322
24469040
|
IKBKG
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
IKBKG
|
CHUK
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
CHUK
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
MAP3K3
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15218148
17145710
9819420
25241761
14743216
10085062
16267042
14636585
9346241
|
MAP4K4
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20685151
10229185
9520446
23915189
26948423
|
IKBKG
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17145710
17485448
16938294
11865184
11877453
16970925
22435554
17244613
17568778
17363905
16818229
15084594
15485931
24369075
20300203
21217011
12799363
23180781
14743216
16319058
21703539
19666608
20098747
12612076
16126728
15218526
23430059
9751060
20138012
18716620
20368414
10837071
25355947
15836773
23109003
20531300
17702576
17363973
15214841
12459277
17561400
21640763
16285893
28462531
12709429
10968790
15199157
26192618
12133805
16497931
11864612
17693255
17072322
11340079
|
SRC
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
12707358
|
ERC1
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15218148
16970925
16497931
15371334
15218526
17072322
|
CHUK
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
113.0
|
1.0
|
Omnipath
|
17145710
15922746
11087742
18074035
12626540
11527961
9244310
11809792
15836773
16177806
9721103
18501560
11923072
17706453
9509763
10723801
11858955
10421793
25133483
10398585
9346484
9346241
21765415
8657102
16737960
9315679
9252186
21490922
16219905
14743216
20484017
10329646
18922877
10882136
16153868
10195894
14751757
16007147
7796813
17053167
9632633
15856023
17965022
10783893
10602462
23602409
27682876
10469655
16965765
15084594
16493072
11095741
12138192
10723127
15210742
10329681
7878466
26930276
9914500
9520446
12514169
12403772
10527519
15145317
16493424
9135156
16023083
12637324
10593898
14636585
9214631
7862124
10074115
15389589
12486103
9891086
8601309
10880512
7739562
16286467
17379600
23109003
9689078
15371334
10733566
29145629
11042193
23970940
10085062
17468758
|
CHUK
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
12482991
19442713
14743216
15494311
11976329
15489227
16382138
16713569
10022904
10469655
27554194
11158290
11297557
|
CHUK
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
9346484
24911653
20932476
28514442
11971985
16970925
12210728
9346485
17965022
16713569
12486103
9891086
15456791
11057907
20434986
16129692
16260493
21903422
21724995
16286467
14743216
16319058
18949366
10779355
25748427
25852190
12244103
11585904
9751060
15218526
10094049
10837071
9914500
21575199
9721103
25241761
10195894
9689078
15214841
21784860
17561400
21640763
16285893
10733566
16186825
16493424
10022904
12709429
12351658
10968790
12547194
15691841
15620648
15327770
11864612
11460167
14636585
17693255
17072322
9346241
|
SRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
22605996
16492141
27177845
23824743
25423132
25850673
24816560
27203386
11836526
22515442
26918136
10593980
15782139
9592087
22056988
12571228
17087658
20840866
23640056
21195420
25164010
26453937
9278444
16831887
23476652
12123611
11279024
14517306
21903109
22200182
20026641
22264731
25041845
12408824
22247700
|
PAK1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
28007610
28423670
23543898
25639486
26547035
22369945
23162742
25472536
21822311
25225063
27713506
27910850
|
PAK1
|
FLNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
18598695
18088087
24278701
12198493
26009991
15024089
25472536
23246867
|
FLNA
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9006895
20156194
23331499
|
NFKB1
|
HSP90AA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17724475
21725609
23178297
23572150
|
HSP90AA1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
1310678
16844778
16189514
18266962
|
SRC
|
HSP90AB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17855507
|
IKBKB
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
IKBKB
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
IKBKG
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
150.0
|
1.0
|
Omnipath
|
17145710
16938294
20932476
35339487
18266324
16260493
27929056
25979343
19666608
26496610
12133833
12192055
9751060
21423167
19706536
15836773
17561400
22099304
23986494
19959994
15327770
25400026
24266532
18450452
12657630
20434986
11583588
20200955
20300203
21903422
22990857
14743216
20167598
20098747
16126728
19656241
25852190
16906147
10195894
17000764
18329793
16186825
16547522
16611882
18037881
10968790
16497931
25286246
18462684
18207244
16603398
17965022
17977820
24240172
17568778
15084594
16129692
23506214
16319058
23123196
18949366
15218526
22605335
20368414
10837071
19820708
10980203
23131831
17363973
15214841
25304104
16493424
15184390
15691841
11864612
15802604
17693255
21455180
11865184
20211142
11971985
16970925
24469399
24618592
12486103
11057907
24369075
19365808
18583959
27426725
12612076
19422324
10094049
23109003
21803029
12459277
21640763
16285893
18266467
12709429
15620648
17072322
19815509
15749833
|
SRC
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17145710
12645577
12707358
15456896
|
MAP3K3
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15218148
17145710
9819420
15572679
11429546
15214841
14743216
15371334
16267042
14636585
16737960
17197697
9346241
|
PLK1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18957422
19202066
|
IKBKB
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
57.0
|
1.0
|
Omnipath
|
31598684
11976329
16713569
10469655
29485707
26999213
12842894
10835356
27187478
27402796
18782567
27554194
12482991
25241761
10022904
15199157
19519322
15489227
19250910
15212693
11158290
11297557
|
IKBKB
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
164.0
|
1.0
|
Omnipath
|
18593939
17145710
18375836
11087742
16793322
11527961
28086098
21232017
12429743
21423167
17693123
21399639
15836773
16177806
9721103
29139553
9271416
17561400
11923072
10889159
17706453
10723801
12791687
11858955
22037600
16365431
10421793
25133483
10398585
9346484
9346241
11158290
18539148
23328071
15574499
21765415
16818647
8657102
18202307
16737960
9315679
21490922
9252186
20001801
15919917
16495515
11368781
16291755
24386391
14743216
25759022
10329646
10882136
16153868
10195894
14751757
18981174
10807933
16007147
7796813
9632633
15856023
17965022
25753787
10783893
10602462
27682876
16965765
15084594
19196987
17322026
12138192
10723127
15210742
16319058
15217903
15218526
7878466
9914500
17367806
9520446
15214841
16846590
12514169
18657515
12403772
10527519
15145317
16888014
16493424
17047224
9135156
15024091
16023083
10593898
14636585
22579987
9214631
24911653
7862124
10320352
16970925
23707515
9346485
12949498
17363905
12486103
9891086
8601309
10880512
7739562
16286467
23109003
9689078
25595906
15371334
16285893
11356195
29145629
23970940
10085062
11815618
17468758
17615396
24586253
17072322
|
IKBKB
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16024783
|
NFKB1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
NFKBIA
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
IKBKG
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
NFKB1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
IKBKG
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
IKBKG
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
17145710
7862124
11087742
10602462
16818647
8657102
16965765
22435544
11064457
24369075
10880512
7739562
14743216
16319058
7878466
16126728
10329646
15836773
16177806
21217772
16153868
10195894
12514169
18617513
15371334
16493424
17706453
15145317
10723801
15870263
7796813
17468758
16603398
17965022
11830587
|
LATS1
|
WWTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
23026745
22078877
20412773
22658639
33086783
24550007
21808241
29787761
34022224
20594350
|
LATS1
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
22863277
24366813
35044719
20048001
18413746
17889669
15302935
21383157
23752589
17974916
18640976
22641346
23027127
20841485
18369314
29179447
18669648
24255178
18565851
21909427
21170084
25283809
29487715
18158288
29496737
18220336
22658639
35210364
27325643
19141641
21041411
25180175
27322327
27847303
|
LATS2
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
36.0
|
1.0
|
Omnipath
|
22863277
20048001
18413746
24525530
15302935
19797269
17974916
18640976
18369314
29179447
18669648
25670202
26578655
29680477
18565851
21233212
21041410
18158288
19919647
18220336
21832154
22658639
21041411
24976283
26598551
|
LATS2
|
WWTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22658639
18227151
21808241
|
LATS2
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21118956
25086053
|
MARK3
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
PAK1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
18593598
27542844
21371233
22105362
22981863
18668521
27169363
12876277
31416844
23331499
33789117
7873542
29551131
28225038
19595712
11435472
9351825
25794709
9416003
21248166
14993270
23701950
18940914
16129686
11948406
23162738
|
MAP2K1
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
149.0
|
1.0
|
Omnipath
|
21675959
9694850
17081983
10757792
11319218
18799465
15592455
12788955
19415658
12697810
17389395
9447970
15342917
8226933
15851026
12270934
12644307
17255949
10998418
11242034
1378617
1381507
17906627
11986622
8376945
8157000
7992057
11948414
9731057
19651622
11251083
11266467
18707149
14743221
11279118
11704645
12750173
12932319
16497976
11337027
23331499
12048245
7559390
17272394
15811950
19494114
18669648
18691976
11741894
15972258
19053285
16094384
17192257
7898932
24623782
9166761
19369195
21336309
12920017
15466214
17016520
19901323
1712480
19690332
11823456
9032297
11134045
12876277
19534553
10995751
20068231
21506533
8223433
8248196
16153436
12594221
10567369
19933846
17563371
11730323
29175850
11352917
16135787
15951569
19058874
15212693
23241949
9560161
91184134
18083107
16887817
18578522
17569879
21071413
9148935
18452278
1330321
8670897
19541618
10777511
15935618
12925710
11971971
9765155
11136732
11118451
12082107
12952943
10746662
21768338
|
MAPK1
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11802164
15239952
21779496
11802165
15260967
|
MARK3
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
MAP2K2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
21675959
11704645
9694850
17081983
7565670
12750173
19690332
12932319
11823456
18799465
15592455
11337027
18083107
21365009
12788955
11134045
19219045
17389395
9447970
15342917
23331499
19534553
17569879
7559390
23047924
8226933
8223433
17272394
15851026
15811950
19494114
18988627
18669648
11549292
23519423
19541618
18691976
1381507
16293107
17906627
11986622
19933846
8376945
19053285
16094384
11971971
17192257
11136732
11948414
8388392
7898932
9731057
11730323
18039929
11118451
19369195
12920017
15951569
15466214
10746662
|
PAK1
|
MAP2K3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10661401
11062502
11385609
11907067
12885870
14764585
15536084
|
MAP3K3
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7839144
12761204
11971971
9162092
|
PAK1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7592586
11304531
15677464
11309380
14970210
|
MAP3K3
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17496910
15574420
19615955
14585353
11777939
16488589
18855897
12738796
12782630
21614932
9162092
21102635
12040186
19568798
11274345
|
MAP3K2
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
10713157
11777939
18855897
9162092
12040186
23331499
21614932
12738796
12782630
21102635
18988627
19568798
14585353
17496910
11274345
14734742
15574420
19615955
7997270
11343802
16488589
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
MAP3K2
|
MAP2K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
21988832
12912994
23331499
19903815
11073940
11274363
24975362
25861671
|
MAP3K3
|
MAP2K5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
12912994
23331499
25241761
16861740
19903815
14743216
11073940
16189514
17985933
24975362
10593883
25861671
12813044
|
MAP2K5
|
MAPK7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
7759517
11544482
24975362
23612709
7646528
23331499
16189514
11782488
12011113
30132833
12912994
15917464
11242034
32296183
29483645
11739740
20667468
9790194
12628002
25861671
|
MAP3K2
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18855897
11274345
21614932
|
PAK1
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7592586
11304531
15677464
11309380
14970210
|
MAP3K3
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18855897
11274345
21614932
|
MAP3K2
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10713157
10347227
21614932
12738796
11274345
9372971
14734742
18855897
|
MAP3K3
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18855897
11274345
21614932
|
MAP2K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
12821118
10713157
11489946
17145710
9362518
13130464
18855897
19690332
95141073
24975362
23331499
7839144
21071413
18362184
11062067
21614932
15911620
12738796
18436711
11389443
10506143
11242024
11847100
18669648
16153436
15725726
25241761
18691976
14523011
25284480
16076903
17192257
11390361
15755722
16533805
19369195
9312068
9207092
9733513
12758252
12624093
15212693
11274345
|
MAP3K2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8226933
15315965
17052767
11971971
|
TRAF7
|
MAP3K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
15001576
14743216
|
MARK3
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
MAPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19604315
15542607
16964243
15212693
11604394
|
MAPK8
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
7890696
15696159
15071501
|
MAPK8
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15071501
|
MAPK8
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
18985696
25862939
15696159
11956222
19788416
21081103
15071501
18559254
7890696
|
NFKB1
|
XIAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17435549
21725609
23178297
23572150
|
NFKB1
|
NFKBIA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
1829648
21725609
23178297
23572150
8096091
|
NFKB1
|
XIAP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15041463
18223231
14739605
16157589
18978816
18761050
15756023
18566231
16453001
|
NFKB1
|
NFKBIA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17876798
15499023
17709515
7775482
11744993
10454561
11060311
12885753
9250151
|
NFKB1
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
25609649
7862124
1340770
16210649
16970925
21719482
9738011
9865693
10497169
8657102
9572494
9315679
21988832
8887676
10329681
1829648
14743216
17003112
11313474
20558726
26496610
7867065
7891711
10837071
7831327
15836773
26186194
11571291
15214841
17561400
16846590
9566883
8096091
15371334
7479976
11020244
9426183
16493424
15145317
8631829
20237821
20980497
16513645
9597130
7479848
7739549
7628694
10655476
|
SRC
|
NFKBIA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
24216290
12432072
24637265
12429743
25671697
14991073
8797825
24101387
9792645
|
PAK1
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26779436
18427546
|
SRC
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16374509
12215529
|
SRC
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
14754902
8755247
11940607
17218263
18434644
10964917
10446041
|
SRC
|
RAP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
14754902
8755247
11940607
17218263
18434644
10964917
10446041
|
SFN
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|
YAP1
|
WWTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
12807903
18280240
18617895
21666501
23708000
25502501
26711338
7782338
|
YWHAE
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
YWHAB
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17085597
12657644
12426317
15071501
|
YWHAB
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
YWHAH
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
12507503
7615088
26496610
17979178
|
YWHAZ
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
YWHAG
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
20936779
17085597
12507503
17979178
|
YWHAE
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
17085597
21827211
12426317
15071501
12657644
17979178
|
YWHAE
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
20936779
17085597
12507503
17979178
|
YWHAE
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
YWHAE
|
YWHAH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
12507503
7615088
26496610
17979178
|
YWHAG
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17085597
21827211
12426317
15324660
15071501
12657644
|
YWHAH
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|
YWHAZ
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|