Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FADD BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15659383 25241761
SMPD1 CASP8 â—¼   COLOCALIZATION 2.0 0.8 intact 8095238 21157428
TNFRSF1A CASP8 â—¼   COLOCALIZATION 2.0 0.8 intact 8095238 21157428
YWHAZ GDI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MADD NUP37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
THRAP3 MADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MADD PTPRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NSMAF SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12391233 20080539
TNFRSF1A SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12391233 20080539
TNF SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080539 0908486107
1433Z MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 16959763
LOX5 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ANM6 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
BBS7 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BBS7 RIPK4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DOCK5 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT12 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX21 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT3 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPK4 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 33961781
MTMR8 MADD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 25659891
NXPH2 MADD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SYT6 MADD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SYT6 SYT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CASP2 PIDD1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SYT3 SYT6 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CASP8 BID â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11832478 12097160 15659383 12196516 9727492 11085743 9727491
CASP8 BID â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor 9727492
TNF NSMAF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8663014 8808629 11435466
CASP8 FADD â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 5219431 17159907
CASP8 FADD â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RAB3A MADD â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 1845915 27246931 7911226 20937701 21776405 16571673 25341920 11516400 12244319 9136770 9020086 8144603
PIDD1 CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15073321 16189514 19203584 16652156
CASP8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9727492 10364179 10805722 11832478 12196516 18458084 9727491 11085742 11085743 12097160 9873064
CASP2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9727492 10364179 10805722 11832478 16189514 11085742 11085743 16495337
CASP2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15262979 16193064
FADD CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
TNFRSF1A CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15357952 12887920 21741934 8875942 15725726
FADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 82.0 1.0 Omnipath 22864571 17145710 11717445 19524512 34591612 15280356 17047155 27552911 12911633 25043603 21458669 11788820 19176810 21525013 21988832 22179575 25939870 12702723 21737330 21741934 26437781 25911380 9228018 21785459 20829884 23972990 21620750 12220669 9774341 17159907 10521396 27321185 17290218 27560715 20103630 24098568 20203691 14612908 8681377 18485876 12107169 15659383 22421964 20448643 9343261 20125124 8681376 12887920 19060883 21737329 23142077 22173242 26972597 22274400 19935698 16410793
CHM MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
CHML MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
TNF FADD â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF FADD â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNFRSF1A FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21760970 15357952 15033800 21741934 9129204
GDI1 MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
GDI2 MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
RAB27A MADD â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21554507 20937701 16571673 23678941 16880209 18559336
TNFRSF1A MADD â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14716293 11577081 19289468 17314102 16682944
TNF MADD â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14716293 11577081 19289468 17314102 16682944
TNFRSF1A MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
NSMAF SMPD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11279185 11435466 12404124 12531547 1330325 16716889 24021978 28765050 8663014
TNFRSF1A NSMAF â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNF NSMAF â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNFRSF1A NSMAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12391233 10187805 17599063 8808629
TNFRSF1A SMPD1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNF SMPD1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNF TNFRSF1A â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNF TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 98.0 1.0 Omnipath 17145710 19084540 8288897 11448951 23746843 22801493 14732063 2848815 9568681 2158863 8182064 9488135 23070005 20080539 11239407 26670046 14743216 21724995 21133840 24070898 25911380 7852363 2170974 17151142 26186194 27560715 25241761 23032187 24726327 20103630 8805640 11502070 19442713 3034874 23955153 18067990 22099304 15485837 22675546 12753742 1310388 12887920 19287455 10634209 2170559 1331108 24980434 22028622