Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2I CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FGFR3 DBNL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DYNLL1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNLT3 DYNC1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DYNC2LI1 DYNLL1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EGFR IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
FGFR3 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
PAFAH1B1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
NOD1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217878 16083881
HSP90AA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 MOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25036637 22939624
HSP90AA1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20133715
PARP1 NUDCD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PAFAH1B1 NUDCD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16754861 0602916103
NUDCD3 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHLPP1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24530606
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
SF3B3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SKP2 USP18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15342634 25307056
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KLHL20 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 20389280 7900485
KLHL13 KLHL9 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CUL3 KLHL22 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DYNC2LI1 DYNLRB1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
MKS1 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26638075
NPHP4 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26638075
BAG2 RAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
BAG2 TAB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
CUL3 KLHL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32753315 21145461
CUL3 MCM7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26188516 21145461
CUL3 SF3B3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23951410 21145461
IRS4 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 24797263
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR FKBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
EGFR PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
MCM5 FKBP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 22863883
SKP2 OFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DBNL PPIA â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
GAN CUL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15983046 31944090 21145461
HDAC6 MCM7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23703321 26186194
SKP2 USP18 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NAT10 PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31616951 34079125
PTPN11 ERBB2 â—¼   DEPHOSPHORYLATION ✅ - 0.84 0.84 Signor 32024694
DYNC2H1 DYNLRB1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DYNC2H1 DYNLL1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FKBP5 MOS â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25036637 26186194 28514442 32707033
RPGR NPHP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 20664800
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
DYNC1I2 DYNLRB1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
ENC1 CUL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 15983046 21145461
EGFR RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
CFLAR RAF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10837247 16189514 16537561 21988832
FKBP8 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 20029029
HCFC1 HCFC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 24981860 15199122
NISCH IRS4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25036637 11912194
RAF1 KEAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 31980649
RPGR NPHP4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 26638075 20664800 28514442
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
DET1 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16964240 33911083 16949367 14739464 17452440 28514442 31155351
EGFR TAB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18271526 31980649 25402006 24658140
DYNLL1 DYNLRB1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
BAG2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14978028 12502846 8692945
KEAP1 CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15367669 28186440 15572695 20864537 25742418 33130828 20534351 20027226 30765703 32854194 23727018 25628777 26757824 17439941 16449638 16790436 21357422 19818716 32341456 20421418 22245129 26219975 22558124 32296183 24896564 15983046 30383469 18251510 24127568 22911784 33391509 15282312 20865015 24322982 21145461 20599909 17822677 22448038 18417180 30273379 15601839
DYNC1I2 DYNLT3 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ERBB2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
MCM5 MCM7 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
DYNC1I2 DYNLL1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
DYNLT1 DYNLT2B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
DYNC1I2 DYNLT1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
DDB1 DET1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CUL3 KLHL11 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
ERBB2 PTPN11 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
DYNLT1 DYNLT3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
DYNC2H1 DYNC2LI1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
NPHP1 RPGR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
NPHP4 RPGR â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NPHP1 NPHP4 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
DYNC1I2 DYNLRB1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MCM5 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ALK PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18320059 19223540 15710330 12522270 12531430 11684012 34301842 8041791 12721296 17483340 32076487
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
DYNC2H1 IFT122 â—¼   UP_REGULATES ✅ + 5.0 1.0 ACSN 18559511 19996169 20360384 21209331 21602792
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
PTPN11 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9756944 16273093 16729043 32024694
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
MCM7 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368