BAD
|
CISD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20010695
7712851
|
KRAS
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16483930
29311131
|
HIF1A
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17558861
19211554
|
BCL2L1
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
RAF1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
MAPK3
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7717053
20154642
|
RAF1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
MAPK3
|
IRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
MAPK3
|
IRS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
HLA-E
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
MAPK8
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033842
16982329
|
TGOLN2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FCGR1A
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
FCGR3A
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
PIK3R1
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
6730400
7589433
|
PIK3R1
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23617393
8427684
|
PIK3R1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7642542
16982329
|
RRAGD
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20006481
18497260
|
MAP1LC3A
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
STX19
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GABARAPL2
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
OPTN
|
HLA-DPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
OPTN
|
RETREG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CANX
|
CISD2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20010695
7712851
|
NSF
|
PTPN9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15322554
8217244
|
NSF
|
PTPN9
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15322554
8217244
|
ATP6V1G1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PRKACA
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ITGB3
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214491
11546839
|
RRAS2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216198
12620389
|
HRAS
|
VPS11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9069260
21779497
|
STX6
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
VAMP3
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
STX7
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
MAPK8
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18471544
|
ATG12
|
ATG10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23725295
24070470
|
ATG12
|
ATG10
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23725295
24070470
|
PIK3R2
|
HLA-E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
HLA-E
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
HLA-E
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
SEC22B
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22153078
25083866
|
HLA-DRB3
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RAC2
|
NCF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213243
11090627
|
NCF4
|
NCF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
5214329
11483497
|
HIF1A
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19132225
20001745
|
PIK3CA
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9148763
10592173
|
PIK3R2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12515821
|
RAC1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9148763
10592173
|
HIF1A
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
23640055
|
CDC42
|
RPS6KB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
CDC42
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11438723
|
M6PR
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19490898
21421921
|
M6PR
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19490898
21421921
|
HLA-DPA1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
HLA-DQA1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
INS
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9609109
15316008
|
IRS1
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11912194
|
IRS2
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8662806
5221055
|
PIK3R3
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0611271104
17360667
|
IGF1R
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7541045
|
COMP
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20033473
32196115
|
GABARAPL1
|
ATG7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20562859
|
PPP2CA
|
FCAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18768864
30766540
|
INS
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9609109
15316008
|
MAPK8
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17050683
18029441
|
NSF
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24119662
19164740
|
RAB9A
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19490898
21421921
|
FCGR1A
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
FCGR3A
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
FCGR2A
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
PIK3CA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
RILP
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RAB7A
|
ATG9A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21169990
8141833
|
FCGR3A
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
FCGR2A
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
FCGR1A
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
GABARAPL1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
ATG4D
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19549685
|
ATP6V1G2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
PIK3R2
|
FCGR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
PIK3R2
|
FCGR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
PIK3R2
|
FCGR3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12869549
15536084
|
HLA-DQB1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11376336
5214072
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
HLA-DQB1
|
HLA-DQA1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
ATG9A
|
TGOLN2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21169990
8141833
|
CYBRD1
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ACTB
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
RPS27A
|
SEC61B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
IGF1R
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
ATG4A
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
IRS1
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16354680
19561084
30240640
|
ITGA2
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
ATG7
|
GABARAPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
ACTB
|
DYNC1H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
RPS27A
|
SEC61A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
ITGA5
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
CISD2
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
32296183
|
RAB7A
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
31871319
|
CDC42
|
RAB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
26344197
|
RHOB
|
STX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
NSF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
BET1
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
29568061
|
RHOB
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
EEA1
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12493736
10491193
|
RHOB
|
RAB7A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
IRS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
KRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
RPS27A
|
SEC61G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
STX19
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX4
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
8153045
21516116
|
STX4
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
32296183
25416956
|
STX6
|
STX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX7
|
GOSR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX7
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX2
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
12828989
24373201
|
RAB7A
|
VPS18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
IGF1R
|
INS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
STX3
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BET1
|
GOSR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
STX4
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
11884531
|
GOSR1
|
NSF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
20562859
9325254
8636227
|
SEC22B
|
STX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
GOSR2
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
ATG3
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
GOSR1
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
MAPK1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ITGAV
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
RAF1
|
RRAS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
STX4
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
25416956
30833792
33961781
|
PIK3CA
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591642
|
STX5
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
30833792
33961781
|
STX16
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
25416956
30833792
33961781
|
RAB7A
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28325809
25445562
|
RAB5A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
RPS27A
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
BET1
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
GOSR1
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
IGF1R
|
IRS1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
17827393
|
RPTOR
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
EIF2S1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
RPTOR
|
RRAGC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25567906
21981924
18497260
31601708
21816923
25446900
31601764
25561175
24337580
|
MBL2
|
CALR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18177377
8062452
|
NSF
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
20562859
|
IGF1R
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
STX1A
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
CDC42
|
NCF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CDC42
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
STX4
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
ATG10
|
ATG7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
12482611
20562859
33961781
26186194
|
STX7
|
STX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
STX3
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
30886144
33961781
26186194
|
NSF
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
20562859
33961781
|
STX6
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
STX7
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
GOSR2
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
25416956
33961781
26186194
|
VAMP3
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
34079125
19557002
|
STX6
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
GABARAPL1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ATG14
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
NRBF2
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
OPTN
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
21779497
|
NCF2
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
PIK3R2
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATP6V0D1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
STX6
|
STX7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BAD
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PIK3R1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
RRAGD
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26582740
24337580
18497260
22424946
|
CFLAR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
16537561
10837247
21988832
|
CDC42
|
RAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31871319
9427749
|
IGF1R
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7559507
8776723
10082579
7541045
8530377
33991522
8895367
12220227
15629149
8662806
|
STX3
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
26553929
33961781
26186194
9614185
12828989
9701566
|
RAB1A
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
GOSR1
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11927603
29568061
33961781
|
STX7
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
29568061
26344197
|
BET1
|
GOSR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
33961781
29568061
|
VPS18
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11382755
16189514
|
RAB7A
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10329441
26344197
|
INS
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
1851182
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ATG7
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ATG3
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CALCOCO2
|
MAP1LC3C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
RPTOR
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
ATP6V1E2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
RRAS2
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
10783161
10557073
11788587
12620389
10064593
|
STX7
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
21516116
34079125
|
STX6
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
21516116
34079125
|
RAB1A
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26824392
|
BET1
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11927603
29568061
9094723
33961781
|
GOSR2
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
STX6
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
33961781
26186194
11278762
34079125
|
VAMP3
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
27791468
33961781
26186194
34079125
11839770
19557002
|
ATP6V0A1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
IRS1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
HGS
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ATG16L1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
GABARAPL2
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ATG16L1
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RAB1A
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
MAPK3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19777442
10597268
12566304
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
ACTB
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NCF2
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16778989
10400704
27558335
|
MAPK1
|
NCF4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16778989
10400704
27558335
|
MAPK1
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17202194
15657136
21419341
|
PPP2CA
|
MAPK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
211739200
12840032
8214413
|
MAPK1
|
GORASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20083603
15834132
|
MAPK1
|
GTF2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10648599
|
NCF2
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16778989
10400704
27558335
|
MAPK3
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17202194
15657136
21419341
|
MAPK3
|
NCF4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16778989
10400704
27558335
|
PPP2CA
|
MAPK3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
211739200
12840032
8214413
|
MTOR
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16847060
26522726
12604610
19619545
26348909
33378666
20169205
24036451
18570873
24516643
19299511
34031390
22424946
22356909
25940091
12719976
22544753
23263282
12150926
12665511
18505677
17277771
17461779
22493283
19114562
18722121
21071439
18030348
19446321
12718876
12747827
24375676
22258093
16837165
21045808
16962653
18955708
17565979
12408816
15467718
23953116
27043084
23911927
17043309
31601708
21177249
21614075
21795849
16631613
20381137
21321085
23297343
23872070
16354680
19875983
25446900
29059166
24337580
16603397
16183647
34171383
15066126
24403073
25332233
17386266
19145465
25007995
16798736
26678875
15268862
20427287
30865892
16919458
25273559
15459249
18519641
18504440
12150925
|
MTOR
|
NRBF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28059666
|
RAC2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7744773
8645157
11803464
|
IRS4
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18165436
11912194
|
NCF2
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12056906
27558335
19372727
|
PRKCD
|
NCF4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12056906
27558335
19372727
|
PPP2CB
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11959144
|
PRKCD
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17183360
16483929
|
AKT2
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17517883
18372248
17277771
|
HIF1A
|
ITGB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20517715
15235127
|
ITGAV
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
ITGB1
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
RAF1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
502464200
8203796
16239230
|
RAF1
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
502464200
8203796
16239230
|
VAMP3
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
16189514
25416956
10820264
34079125
12130530
12828989
|
CFLAR
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19838173
|
ATG3
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
11825910
20723759
24186333
23202584
17353931
20562859
33961781
30778222
34079125
|
RAC2
|
NCF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9624165
9642115
16189514
11090627
|
NCF4
|
NCF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16297854
11893732
9490029
10672014
11483497
16782902
11796733
12887891
9083043
12813044
|
RAC1
|
NCF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25301945
9642115
16189514
25416956
9255350
8036496
11896062
11090627
9624165
7738010
|
NCF2
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7738010
9642115
16189514
11090627
|
ITGA5
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
ITGB3
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
MAP1LC3C
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20562859
22170151
|
HLA-DQA1
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
HLA-DPA1
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
PPP2CB
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
2826472
11124802
10200280
|
GOSR2
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
16189514
9094723
9647643
11927603
11035026
|
RAC2
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7744773
8645157
11803464
|
EEA1
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11493665
16902405
15016378
11870209
10720461
34079125
11718716
9697774
10491193
14600265
20534488
15328530
|
RILP
|
RAB7A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26911690
25445562
18552835
18787122
30721249
26496610
11448994
25080504
32814053
15933719
33961781
25908847
25533187
11179213
34432599
|
RAB33B
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18448665
|
NRBF2
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
28059666
32296183
24785657
|
ERN1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18471544
27009865
|
PIK3R2
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22402981
8596638
11733063
|
HLA-DQA1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
GABARAP
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
DYNC1I2
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
MTOR
|
AKT1S1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
18372248
|
RPS6KB1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
HLA-DPA1
|
HLA-DPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
IRS1
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
STX6
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PIK3R1
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
6731578
14632132
|
IRS2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
IRS1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATG7
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
DYNC1H1
|
DYNC1LI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.93
|
0.93
|
mint
|
30194290
|
ATG7
|
ATG12
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
18704115
|
RAB1A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
SEC61A2
|
SEC61B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
ATG7
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
12482611
11890701
20562859
28253953
11096062
|
ATP6V1B1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
RAB7A
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
34079125
22939629
10329441
26344197
|
ATP6V1C2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATG12
|
ATG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
PIK3CA
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PIK3CB
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
ATG7
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
SQSTM1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
19427866
7034152
|
ATG3
|
ATG7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
11825910
24186333
20562859
33961781
26043688
|
RRAGD
|
RRAGB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
18497260
33961781
28716898
11073942
20381137
24337580
22424946
|
GOSR2
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
GOSR1
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB7A
|
VPS11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RRAGB
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
SEC61B
|
SEC61G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATG10
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
12482611
17353931
33961781
26186194
|
RRAGC
|
RRAGB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
25567906
21981924
33961781
28716898
11073942
20381137
25561175
24337580
22980980
22424946
|
RPS6KB1
|
MTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
15905173
|
MTOR
|
RPS6KB1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.96
|
0.96
|
Signor
|
12782654
|
ATG3
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
ATG12
|
ATG16L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
SEC61A1
|
SEC61G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
ATG16L1
|
RAB33B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
PIK3R1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20018188
7383613
|
OPTN
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
20161783
20388642
23357852
20634958
22854040
11137014
20085643
|
ATP6V1B1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
KRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
MTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EEA1
|
RAB5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
SEC22B
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
RAB7A
|
RILP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
RPTOR
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
24036451
|
MTOR
|
RPTOR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
21045808
8088164
|
HRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
RAF1
|
HRAS
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
ATP6V1E1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
DYNC1H1
|
DYNC1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ITGA5
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
IGF1R
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ATG3
|
ATG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
PIK3CA
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
MTOR
|
RPTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.98
|
0.98
|
Signor
|
19346248
|
GOSR1
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
9094723
9647643
9325254
12388752
11927603
|
VPS11
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
26496610
33961781
26186194
11382755
25783203
23901104
28931724
|
VPS11
|
VPS18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
RPS6KB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ATG12
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
HLA-DQA1
|
HLA-DQB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
IRS1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
SEC61A1
|
SEC61B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RRAGB
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RAF1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11532940
12107820
12566895
14764585
15516985
19289794
19565474
24027568
8929532
9069260
|
PRKCQ
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10652356
15214048
15536066
16606694
17544292
17548359
18784374
19201850
23077238
23433459
23474202
23886063
25960930
|
MAPK8
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
11983683
12189144
14673001
16166315
15526032
29795446
15907327
14967141
15725726
17555943
|
PRKACB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
PRKACG
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
15280015
10611223
10230396
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
RAF1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
11983683
12444011
10880354
19030972
19667065
22096607
15849194
16931767
17535812
16103085
9381178
23162742
12107820
18402774
12767520
10826997
8929532
8929531
12175651
25241761
19565474
10949026
19165420
9069260
21540285
17242355
23397142
19289794
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
RPS6KB1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
11493700
10230394
10558990
8929531
9381178
19641507
17270021
10837486
|
PRKACA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
11983683
10880354
20166139
9346240
11493700
9381178
18794113
12931191
15280015
10230394
10558990
8929531
18669648
10837473
10837486
10611223
12954615
10949026
10851172
15123689
18707149
16403219
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
MAPK8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
10617621
25241761
15733859
12633850
18471544
|
BNIP3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
10625696
|
HIF1A
|
DDIT4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
DDIT4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19828020
17307335
20176937
|
HMGB1
|
CD14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10952726
11672593
12646658
12803886
15802534
16267105
16327802
19931333
21372296
22842346
26618107
27048821
27192565
|
NRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RAF1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
HRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
PPP2CA
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
12624094
12840032
18039929
16680151
16456541
10995457
18042541
10592173
7780739
18588945
2154696
20626350
|
PPP2CB
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18039929
16680151
16456541
10995457
18042541
7780739
18588945
2154696
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK1
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15616583
|
MAPK1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
17081983
18767875
15849194
19690332
11409918
14654779
23331499
23180781
8226933
20068231
18988627
21917714
18669648
19541618
18691976
16407412
19933846
9922370
15664191
8388392
19651622
10801873
8349614
18775330
9604935
|
MAPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
12054624
15547943
20080742
14967450
12040186
15173823
12697810
11940578
7545671
16227978
21035469
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
19085255
11279232
9271440
18039929
18775330
11705993
10601235
12792650
11431469
|
MAPK1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21071439
19339977
19864431
21325048
22493283
|
MAPK1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16954218
10551817
18519666
18687685
26784107
|
MAPK1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
15001544
17081983
18949383
16123357
27014871
16914728
17360977
16099428
30401435
16131083
17640984
12510059
15613682
21850561
14579029
20594869
8626671
9395471
19651622
15576463
22289259
14769130
16020478
17242212
|
KRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
NRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
HRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RAF1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
PPP2CA
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12624094
12840032
18039929
16680151
16456541
10995457
18042541
18588945
|
MAPK3
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21757713
21071439
19339977
19864431
|
MAPK3
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
15547943
20080742
14967450
12040186
15173823
12697810
11940578
16227978
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
11279232
9271440
18039929
18775330
10601235
12792650
11431469
|
MAPK3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10551817
18519666
24099156
|
MAPK3
|
GTF2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10648599
|
MAPK3
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
15001544
16131083
8626671
14769130
9335553
15613682
12510059
15212693
9395471
14579029
|
MAPK3
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
25241761
15616583
26769850
|
MAPK3
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
14654779
23331499
19541618
18691976
16407412
19933846
9446616
9922370
15664191
18988627
|
RAC1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
10702316
10722653
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16556040
16678438
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18481918
18492954
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19720745
19864431
20027184
20138985
20338997
20547845
20805416
21157483
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9069260
|
MTOR
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RAC1
|
MTOR
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
10702316
10722653
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16556040
16678438
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18481918
18492954
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19720745
19864431
20027184
20138985
20338997
20547845
20805416
21157483
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9069260
|
MTOR
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
SQSTM1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
25002027
26587781
28574505
|
RAC1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
56.0
|
1.0
|
ACSN
|
10702316
10722653
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16556040
16678438
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18481918
18492954
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19720745
19864431
20027184
20138985
20338997
20547845
20805416
21157483
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9069260
|
MTOR
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RAC1
|
MTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
56.0
|
1.0
|
ACSN
|
10702316
10722653
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16556040
16678438
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18481918
18492954
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19720745
19864431
20027184
20138985
20338997
20547845
20805416
21157483
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9069260
|
MTOR
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RPTOR
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
139.0
|
1.0
|
Omnipath
|
15268862
24403073
20427287
22258093
21321085
19446321
15467718
19875983
17461779
12665511
12719976
16631613
21045808
21177249
23911927
24337580
25446900
24516643
18614546
12718876
12747827
16603397
17043309
18519641
22544753
25007995
27043084
19145465
23953116
19619545
16919458
24375676
15459249
16837165
16847060
25332233
12150926
22424946
26348909
12150925
18955708
20381137
22356909
17386266
17565979
18030348
16354680
20169205
19114562
21071439
27329724
35561222
16798736
15809305
22493283
17277771
15661536
16962653
1683716516603397
17604271
18676370
16183647
18505677
23297343
23872070
24036451
15066126
18570873
21614075
18722121
12408816
17599906
|
MTOR
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
111.0
|
1.0
|
Omnipath
|
25062042
17510057
17081983
15208671
22873724
16922504
23077579
12087098
28270148
16286006
15896331
25356520
17664694
21790669
26919095
26313911
21561857
10567431
16099428
21977024
14679009
11940578
15899889
15388791
12829246
21980324
22751450
12604610
9465032
20068231
10601311
28122439
19302577
21602892
15718470
15631631
23273915
18669648
21307646
10579915
23261705
20169205
25936802
25486097
24411482
12586835
23342114
15809305
14560963
22472346
11279232
15760907
9271440
27856330
12370290
23486913
12782654
11914378
24795562
19877273
28242756
11500364
26698305
14993219
20459645
23029019
16964243
15212693
25505994
|
MTOR
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20338882
17517883
18372248
19203586
27418134
17277771
15718470
26491696
|
MTOR
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
22570710
15952059
19561084
21282364
25973388
14769130
11287630
9335553
17698034
20863384
|
MTOR
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17517883
18372248
19203586
17277771
15718470
|
MTOR
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
17604271
17386266
18030348
28978182
19114562
17517883
26876939
18570873
18372248
17277771
|
NRAS
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3CA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
KRAS
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HIF1A
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835053
20724477
14726529
11359907
16682453
15833446
16982770
16618748
|
HRAS
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9069260
25241761
10212255
11313862
9150145
16713569
15021914
|
IRS2
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21241768
23439647
11024460
19561084
12107746
9334184
15715521
11438664
15514089
26496610
9233603
23617393
8910607
9852124
19109239
|
IGF1R
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8603569
17496910
25241761
8697095
7642582
17570479
18595745
7589433
|
CDC42
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7629060
8034624
9381982
|
IRS1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
12444011
11788580
14632132
14511371
19030972
16931767
7486683
21798082
11403293
12173038
8382612
12220227
12767520
10826997
16230374
7680095
23439647
19561084
16150444
12107746
10358772
11748924
12175651
7499365
7935461
15316008
9564850
16354680
16043515
12730242
11416002
7680644
23643389
21540285
8628286
15514089
11438664
8175658
9233603
1381348
25814554
|
PIK3R1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7629060
8034624
12086876
12515821
|
PIK3R1
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7629060
8034624
9381982
|
PIK3R1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8596638
25241761
20713702
27107012
11733063
21825134
32814053
26496610
8139559
14729945
10358930
14665640
|
PPP2CA
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11959144
|
PRKCD
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11884618
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
PRKCD
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
15364919
17081983
16131083
15069075
15199052
23328071
16129690
12031982
15143153
18285345
14583092
16611834
15212693
15516986
16099428
12351658
|
PRKCD
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23823319
16301335
29903913
11700305
17107954
18550856
25278023
12682249
15212693
|
PRKCD
|
NCF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15035643
9804763
|
RAC1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10702316
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19864431
20138985
20547845
20805416
21157483
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RAC1
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10702316
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19864431
20138985
20547845
20805416
21157483
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RAC1
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
10702316
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19864431
20138985
20547845
20805416
21157483
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12150925
12777372
15755954
15854902
16469695
16915281
17991864
19299511
19864431
19942859
20484410
22025673
22841746
23087689
26159692
|
RPTOR
|
SQSTM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12150925
12777372
15340068
15755954
15854902
16252010
16469695
17991864
19299511
19864431
19942859
20484410
20531300
21981924
22025673
23087689
25002027
26159692
26587781
28574505
|
RAC1
|
RPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
40.0
|
1.0
|
ACSN
|
10702316
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19225151
19244117
19446321
19568798
19706736
19864431
20138985
20547845
20805416
21157483
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RRAGC
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21816923
25561175
20006481
18497260
24337580
25446900
21981924
|
AKT1S1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17604271
17510057
18030348
17386266
18215133
17517883
33230243
|
RPTOR
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16183647
12087098
12604610
9465032
28249155
12150926
|
GABARAPL1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
21691068
25416956
31053714
16189514
32296183
21617041
19250911
|
MAP1LC3A
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
20061800
23022382
23459205
35044719
22963397
36036324
31053714
21045561
25921531
19250911
17580304
21628531
20204693
28740232
23640897
25686248
24100292
26075355
20562859
22658522
25984893
21460636
16286508
19427866
32296183
23989536
19021777
26268733
22714671
24998849
18653543
31366950
33436498
16169070
23239879
26754771
|
GABARAPL2
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
17353931
24582747
25416956
33436498
31053714
16189514
32296183
21460636
19250911
21900206
|
RHOC
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21576392
15507212
22275430
16439214
23222643
24914801
22094460
|
ACTB
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
24914801
15507212
16439214
22608513
|
ATG3
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20562859
17145710
17353931
16303767
|
ATG4A
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12473658
17347651
|
ATG7
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15197469
20562859
17145710
11890701
16303767
11096062
|
ITGB2
|
CD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
10201950
16751103
3537192
2462607
|
HIF1A
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
15235127
1823643
16716598
12829734
9159130
13130303
9746763
12080085
11566883
10403805
8943284
15451019
9278421
16887934
|
PTPN9
|
NSF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15322554
|
ATG7
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
11096062
|
ATG3
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11825910
17145710
16303767
20562859
|
GABARAP
|
ATG7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
11096062
|
ITGAV
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
ITGAV
|
ITGB3
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
10022831
10545505
10837075
11146654
11335727
11532940
11553709
12000961
14697347
15031725
16919435
18353785
19161977
19339212
19449109
22035837
7512751
7529872
7657702
8636223
8755653
9295024
9763615
|
ITGB1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
HRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RAF1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
KRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
10958680
12750173
9516156
12932319
9665134
10783161
8805624
1386920
1639773
8340422
8601312
19595761
23331499
16041367
21071413
8332195
9446616
10882715
25852190
10531446
1996324
19029954
8503013
16093354
19541618
23153539
16293107
1708096
19933846
26721396
11136732
10205168
20802526
31980649
7760835
18775988
8307946
12917261
11134016
20080631
8180183
1990291
|
PRKACA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
19007248
11971957
20166139
18767875
20230923
9001246
10576742
23331499
20068231
7935389
18669648
18691976
9922370
15664191
19651622
12801936
9091312
10862777
9710607
11997508
|
HRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
147.0
|
1.0
|
Omnipath
|
17145710
18273062
9523700
1639773
8601312
19595761
20133694
11032808
9154803
10882715
14654780
1996324
19222999
16301319
11948414
8530446
7969158
11313862
9150145
20080631
1990291
12750173
15031288
12932319
9665134
8805624
8340422
1386920
23331499
16916524
16041367
23180781
18988627
20178605
15688026
15664191
22169110
11733498
7862125
8180183
19063885
12391160
9144171
8035810
9020159
14724584
19696784
21779497
9261098
12173045
12620389
8628317
19914712
1708096
19933846
26721396
7730360
10205168
8332187
16803888
18775988
12917261
9099670
10545207
25684575
8670882
10783161
12379659
10887184
17569879
21071413
8332195
7523381
10531446
24929361
8503013
16093354
19541618
10369681
8911690
18073111
11136732
10922060
7760835
11134016
|
RRAS2
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12620389
10064593
11788587
16189514
10557073
10783161
|
PPP2CA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18039929
7604263
16680151
16239230
10995457
18042541
18588945
|
NRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
9867809
12750173
12932319
9001246
9665134
8805624
1386920
1639773
8340422
8601312
19595761
23331499
21071413
8332195
10531446
10882715
7811320
1996324
18988627
21779497
8636091
8503013
7766599
16093354
19541618
8180183
1708096
19933846
32296183
9525741
8876196
11136732
10205168
21478863
7760835
18775988
12917261
11134016
18641128
20080631
9488663
1990291
|
PIK3R2
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11525649
8137421
16810318
16713569
|
HRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
9069260
9113989
8052307
24412244
17540175
9931431
11313862
14724584
10592173
9150145
8665852
10783161
|
DAPK1
|
PPP2CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
DAPK1
|
PPP2CB
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
DAPK1
|
STX1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12730201
|
CFLAR
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12215447
15760909
17462996
19838173
23301705
23377657
23725295
24070470
26972597
|
CFLAR
|
ATG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12215447
15760909
17462996
19838173
23301705
23377657
23725295
24070470
26972597
|
ATG14
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG12
|
ATG3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG10
|
ATG12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17145710
16963840
12482611
17353931
10508157
11265251
18704115
|
ATG7
|
ATG12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
20562859
15197469
11265251
11890701
9759731
11100732
18704115
11096062
12482611
|
CD14
|
ITGAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
10201950
16751103
3537192
2462607
|
CYBB
|
NCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
CYBB
|
NCF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
CYBB
|
RAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11145705
1660188
18347018
11090627
10455184
|
CYBB
|
NCF2
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
CYBB
|
NCF4
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
NCF2
|
NCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
NCF2
|
NCF4
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
RAC1
|
NCF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9624165
11090627
9642115
25416956
16189514
7738010
25301945
11896062
9255350
8036496
|
NCF2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
9624165
11090627
9642115
25416956
16189514
7738010
25301945
11896062
9255350
8036496
|
RAC1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17251915
12213839
18423204
18426980
10592173
22252525
10930450
|
HIF1A
|
BNIP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14612449
11457733
18752464
17878221
|
HIF1A
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20864819
17848618
11559532
20332243
19745228
17513511
11550088
10922063
12879018
|
HIF1A
|
BNIP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16585195
19136941
18054315
11559532
|
CDC42
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
25241761
12213839
25284480
18426980
10930450
|
STX16
|
M6PR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
KRAS
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
Reactome
|
23943869
26590425
9436858
11585916
29311131
20802526
25713064
16483930
24033119
27697864
|
PRKCQ
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15364919
17081983
26956053
25381390
17709744
|
IGF1R
|
IRS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10086337
10826997
11274345
12175651
12444011
12556535
12655147
12767520
16931767
17145802
17673906
19030972
21540285
24103846
24782617
|
PRKACA
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17360977
12624099
|
RPS6KB1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
47.0
|
1.0
|
Omnipath
|
21283818
17081983
16953237
24931005
11287630
15249583
27898058
16914728
25379019
23565163
15364919
15533996
19121779
9312143
17709744
20074531
22523661
23958494
16129690
23006971
23898460
26474286
28342808
17507185
25813876
26926384
15306821
20932932
34013180
15199052
18498745
18952604
18220336
12006582
19369195
29496905
27889207
26666849
|
IGF1R
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
7541045
12444011
19030972
10082579
16931767
21798082
12220227
11259577
12767520
10826997
23331499
17827393
7504175
21071413
7559507
11572799
27856640
12175651
17570479
15829723
18988627
15629149
11557037
20670944
8530377
21540285
8776723
25886138
8662806
|
MAPK8
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15001544
18728222
26882989
12409308
10592173
15314024
12417588
15613682
14579029
10722755
26538579
29207597
15199052
12351658
16055440
11606564
12510059
15212693
|
INS
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
25309812
25472611
23891856
20150288
29069585
24036112
21518983
11160134
19357636
22198320
17579213
21677282
11684411
23983791
28955049
25760026
21850561
22832498
19808019
22698915
23815272
18443205
20601126
16150913
25383313
27695421
23115649
22728334
19752148
19171749
27819676
16516141
22418434
19542202
25381390
22516431
24763529
26866272
23695665
23431498
|
IRS1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
11120660
7559478
10358772
16931767
12730242
12175651
7499365
15316008
|
IRS1
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
9415396
16931767
12175651
10417350
7542745
25814554
|
IRS1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
16354680
16150444
16931767
10592173
12175651
1380456
23643389
1381348
11313948
9374521
20966354
9624169
|
IRS1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
16931767
14623899
11416002
12175651
|
INS
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
1851182
18988627
|
IGF1R
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9553137
18988627
11316748
|
IGF1R
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17496910
25241761
9415396
9524259
|
IGF1R
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
8662806
9852124
10471495
|
ATG7
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
22170151
16303767
|
ATG7
|
ATG10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15197469
11890701
12482611
9759731
11096062
|
ATG7
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15197469
11825910
|
MAP1LC3A
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20562859
25503391
19838173
16303767
22170151
|
IRS2
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10594015
19109239
9651378
15715521
|
IRS2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9113989
22810696
9374521
|
SEC22B
|
NSF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
SEC22B
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
21532587
24917561
20966969
17287728
|
SEC22B
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
INS
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20338882
25304263
30179516
23832510
23801578
22307032
20041157
24725432
|
RAB1A
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
PPP2CB
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
18039929
19216069
10026142
10995457
18042541
20452955
18559511
8650155
18588945
16680151
16406523
|
PPP2CB
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
PPP2CA
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
PPP2CA
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16109716
2826472
16899564
11438723
11124802
10200280
|
PPP2CA
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
GOSR2
|
NSF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
STX16
|
NSF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
STX6
|
NSF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
NSF
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
NSF
|
STX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16912714
8221884
8620540
19164740
|
AKT3
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20016067
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
BET1
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
STX5
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
GOSR2
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
STX16
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
PIK3R3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8596638
22402981
9415396
11733063
26496610
25814554
|
NRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8052307
7820549
9150145
8665852
21779497
|
PIK3CA
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
15854902
19225151
20097763
21123297
30021155
24990947
20068231
19079619
15809305
20599721
14623952
11279232
34518212
33800846
18669648
|
RAB5A
|
EEA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
15328530
17145710
20534488
14600265
11718716
10491193
11493665
11870209
16902405
15016378
10720461
9697774
|
MAPK8
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21988832
17570479
11279232
23816567
|
RAC2
|
NCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11145705
1660188
18347018
11090627
10455184
|
RB1CC1
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
23262492
23392225
24954904
24100292
|
AKT2
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17329361
19651622
17081983
17386266
17517883
12524439
11352916
20068231
18372248
19413330
17277771
14973226
18669648
23682635
|
AKT3
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17440074
17517883
18372248
17277771
|
MAPK8
|
CTBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
28532298
14567915
17496919
19591900
21372320
19788416
15708980
8608010
16984892
20512932
20220133
21438496
20054826
19616017
23762064
15611655
|
NRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
KRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
PIK3R2
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3R2
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
ATG101
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
23392225
19597335
|
HLA-DQA1
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DOA
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|