Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
STX12 VAMP4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NAPA VTI1A â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RHOB STX7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
STX7 VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 34079125
BET1 STX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 33961781
RBNS5 EHD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NPAL3 VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STX12 BET1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
ESR1 VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
RHOB LSR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
LSR VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
VAMP4 VPS45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STX12 VTI1B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
NAPA STX6 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
STX16 VTI1A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
VTI1B STX12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B VPS45 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BET1 VTI1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 33961781
STX7 VAMP4 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
VTI1B SNAA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 30833792
VAMP4 SNAA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 30833792
SNAA VPS45 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 30833792
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
STX6 SNAA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 26186194 30833792
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
VAMP4 STX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19557002 26186194 28514442 34079125
VTI1A STX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 11101518
STX7 STX12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 34079125
SNAA VTI1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 30833792
VAMP4 VTI1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 11839770
STX7 VTI1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
STX16 VAMP4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
STX6 STX7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
VAMP4 VTI1A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTPN1 IGF1R â—¼   DEPHOSPHORYLATION ✅ - 0.87 0.87 Signor 11884589
STX7 BET1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 33961781 26344197
VTI1B STX6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27791468 26186194 28514442 34079125
SNAA BET1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 33961781 30833792 26344197
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
STX6 VPS45 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 34079125
RBNS5 RAB5A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11062261 20534488 29568061 16034420 15328530 34079125
VAMP4 STX16 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 11839770 32296183
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
STX6 STX12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17159904 26186194 28514442 34079125
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
STX12 VTI1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NAPA VTI1B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
STX7 VTI1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RAB5A ZFYVE20 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
STX12 STX6 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
STX6 VTI1B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NAPA STX16 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
NAPA STX7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
NAPA STX12 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
STX6 VTI1A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
STX6 VAMP4 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
SNAA STX16 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 30833792 26344197
IGF1R PTPN1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
STX7 SNAA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 30833792 9417091 26186194 28514442 16189514
STX12 SNAA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 9817754 30833792 9507000 26186194 28514442
EEA1 RAB5A â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RBNS5 VPS45 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 26344197 25416956 11062261 19931244 28514442
VPS45 STX16 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 28514442 12110575 32296183 33961781
STX16 VPS45 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
VPS45 ZFYVE20 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
STX6 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
RAB5A EEA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15328530 17145710 20534488 14600265 11718716 10491193 11493665 11870209 16902405 15016378 10720461 9697774
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
PTPN1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 11884589 15976035 8702689 16926280 8999839
STX16 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
VAMP4 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740