Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FXR1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ARPC2 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
ACTB ARPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
ANXA11 HNRNPH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DDX39B API5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FXR1 AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CALM1 MYH14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 3079756 3839510
CALM1 MYH9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 3079756 3839510
CAPN1 XIAP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19931333 28747251
CAPN1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8695851
XIAP CASP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547707 9525868
CASP9 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
CASP9 DIABLO â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14960576 11084335
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK1 EIF4G2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29530922
PPP1CC CDK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21533037
FXR1 CIR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CIR1 PLRG1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EIF4G2 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943866
FXR1 MYH9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 HNRNPH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GTF2A1 TAF2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HNRNPA1L2 HNRNPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LONP1 MT-CO2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
TP53 NDRG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
PAK4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27496712
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PRPF4B SF3B4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PRPF4B SF3B3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
S100A16 S100A14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 S100A6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20591429 31837246
SF3B4 USP39 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPL29 RPL5 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SF3B3 USP39 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
GFM1 MRPS22 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
GFM1 MRPL49 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
SNRNP200 USP39 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ANXA11 PDCD6 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
PAK4 ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29100370 19778628
CDC73 MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27462432 22863883
CDK9 CDK12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 23602568
DDX39B SF3B3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RCC2 PAK4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29100370 25074804
MRPL49 MRPS22 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MRPL9 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MYH9 ACTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22366308 26496610 16186248
RPL10A RPL21 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ACTR3 ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTN4 VCL â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF4A3 SNRNP200 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF4A3 PLRG1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RPL18A RPL21 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SNRNP200 USP39 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PSMD12 PSMD13 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TP53 S100A4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 19740107 7256480
EIF6 FBL â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CDK9 CDC73 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17643375 26659056
HTRA1 XIAP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28642151 21387310
PPP1CC PPP1R10 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
RPL21 RPL35A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL10A RPL35A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MRPL49 MRPL9 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PRPF4B SNRNP200 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AXIN1 PPP2CA â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
RPL21 RPL5 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
COBL ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125
S100A4 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PELO RPL21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DYRK1A RNF169 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PELO RPL35A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PELO RPL18A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
TPM1 TPM3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PELO RPL12 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RPL18A RPL35A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
GFM1 MRPS9 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
MYH9 S100P â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31837246 15171681
RAB7A RAB5C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GFM1 MRPL9 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RPL10A RPL5 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HTRA4 XIAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31036715 31470122
PRPF4B USP39 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
PSMD12 TXNL1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
RPL35A RPL5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ACTB ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CCT7 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CDK1 RANBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26051540 17570479
EIF3L EIF3E â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 16189514 22939629 19748344 18599441 22863883 28514442 11590142 17403899 23623729
XIAP HTRA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31470122 31260151 28642151
RNF114 MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
EIF3E EIF3L â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
PPP1CA PPP1R10 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RPL18A RPL5 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
EIF6 RPL29 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PLRG1 SF3B4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PELO RPL5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
S100A13 S100A14 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
XIAP DIABLO â—¼   UBIQUITINATION ✅ - 0.91 0.91 Signor 15749826
EIF6 RPL12 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PDCD10 PPP2CA â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PSMB3 TXNL1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RPL10A RPL18A â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
MCM4 MCM6 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
PSMC1 TXNL1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
MRPS22 MRPS9 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
SF3B4 SNRNP200 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MRPL9 MRPS9 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PSMD13 TXNL1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PSMA6 TXNL1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
S100A14 S100A16 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MRPL49 MRPS9 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDK9 CCNT2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17643375 10465067 9499409 23455922 11713533 33961781 26344197 24981860 27684187 18566585 21729782 26186194 11282025 28514442 16331689 23602568 32707033
EIF6 RPL10A â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MYH9 S100A4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EIF6 RPL21 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
EIF6 RPL35A â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PLRG1 SF3B3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP7 XIAP â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF6 RPL18A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PLRG1 SNRNP200 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL18A RPL29 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL29 RPL35A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SF3B3 SF3B4 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PSMA6 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMB3 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMB4 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC1 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC5 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PDCD10 PPP2R1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD12 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL35A RPL5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SF3B3 SNRNP200 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
DIABLO XIAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3E EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPL29 RPL5 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCNT2 CDK9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB4 PSMC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF6 RPL5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMB4 PSMC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL10A RPL35A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL12 RPL35A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL21 RPL35A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COX6B1 MT-CO2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB3 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB3 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB3 PSMC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB4 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC1 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL29 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL12 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL12 RPL29 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL35A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL21 RPL29 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC1 PSMC5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL21 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL21 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL18A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPL21 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL21 RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMB3 PSMB4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL10A RPL18A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
MYH9 ARPC5 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
PPP2CA AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19131971 23331499 10644691 9920888 10026142 11742073 10995457 18042541 18559511 16680151 10421629
PPP1CB AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17318175
PPP1CC AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17318175
PPP1CA AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17318175
XIAP CAPN2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11583623 12815069 12835328 21887410 23242420
MAPK3 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 26248159 14993287 10644690
CASP7 DIABLO â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14960576 11257231 18619610 9230442
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 16916640 9922454 11752425 11701129 12824163
CASP9 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17899380 9922454 16352606 9598997 9651578
XIAP CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 11447297 11257231 18521960 31467278 15200957 9384571 9545235 14512414 23979166 16189514 11359776 9230442 10508158 19559631 11257230 9525868 11583623 15580265 11257232 23074197 19698783
DYRK1A CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19081073 19016842 19586613 24922073 17466630 12792650
CDK1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 19081073 19016842 16287866 29844931 19586613 29416675 17466630 12792650
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783
PPP1CA CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22311969 12792650 16888006
CDK1 MCM4 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 MCM6 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17081983 17303408 19793801 15279786 7575488 11454864 16517729 20068231 17116885 17582221 16519687 18669648 18590585 12714602 17660363 17296725 17924679 17102137 16964243
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
XIAP DIABLO â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10929711 11140637 15078891 17435549 22733138 23070005 26587781
DIABLO XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 17686459 15280366 11257231 11157976 11606597 15650747 10929712 11927604 12218061 15200957 15541727 12865429 10929711 11801603 14512414 27476169 15178455 16189514 25246529 15300255 15507451 11140637 11604410 11140638 15078891 14523016 12525502 20957035 12660240 17179183 25801170 11257230 11242052 23251006 23818254 11801595 16282325 19506082 31699976 12511567 17724022 11583623 11602612 22465666 21185211 15749826 15781261 12181739 19667203 32447208 12121969 10972280
DYRK1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20696760 24901999
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MCM4 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MYH9 MYH14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB MYH14 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
S100A4 MYH9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9405067 22460785 15289939 16707441 22483112 31837246 20421509
TP53 NDRG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15377670 11237058 18431400 17442733
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
TP53 S100A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647
S100A4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368