Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
DVL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRB2 HTRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NOS3 HTRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
HTRA1 MAPT â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
MGT4C HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEU2 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DB127 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CL049 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
REG4 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ISK4 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEF5 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FUT1 HTRA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEF5 LTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APOE MAPT â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CTNNB1 PITX2 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
TMM25 HTRA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HTRA1 XIAP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28642151 21387310
BCAR1 GRB2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
HTRA4 XIAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31470122 31036715
APOE TAU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7566652 9512010 32814053 26402096 9147408 8620924
HTRA1 TAU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26436840 22535953
RELA COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10541434 11277268
BCAR1 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10085298 16105984 8649368 8700507 10822386
THBS1 LTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22943793 8349738 21900405
APOE MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9512010 8620924 7566652 9147408
RELA XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
DVL2 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
RELA NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18397880 14570928 17081374
THBS1 LTBP1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10657674 11982756 14568985 14996710 21900405 22943793 8349738
CTNNB1 PITX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 25241761 21071413 19174163 12464179 15728254
ACAN HTRA1 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 14973287 21297635 19657146 9852107