ESR1
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
16582100
|
CAPZB
|
CAPZA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CAPZA1
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15473859
15738427
|
DAPK1
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DCTN1
|
HDAC6
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5215415
12024216
|
SH3BGRL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
ESR1
|
GNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19170076
18414489
|
ESR1
|
INA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14605097
|
MYH9
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DCTN1
|
DCTN4
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
ARPC1B
|
ARPC4
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
ACTR2
|
ACTR3
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
TWF1
|
TIGAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
ANLN
|
DREB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
LIMA1
|
DREB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
ACTC
|
ANLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
30890647
|
ANLN
|
CAZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
FLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
BASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
SYNPO
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
MYH9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
TMOD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
MYO1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
BMI1
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34316702
24457600
|
BMI1
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34316702
24457600
|
CFTR
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
31324722
|
EGFR
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
20029029
|
EGFR
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
31980649
|
CAPZA1
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
ACTR2
|
ARPC1B
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
TWF1
|
ACTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12207032
30890647
|
HDAC6
|
CFTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
14675537
22069321
|
DREB
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
26496610
|
DAPK1
|
CAZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25852190
32707033
|
CAZA2
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
26496610
|
ARPC4
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
24981860
|
DAPK1
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25852190
32707033
|
DAPK1
|
TMOD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25852190
32707033
|
DAPK1
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25852190
32707033
|
LIMA1
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
26496610
|
MYO1C
|
TWF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
26496610
|
ACTR10
|
DCTN1
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
RNF8
|
TWF1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.85
|
0.84
|
PKG
|
28854368
|
CFTR
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
17110338
|
CFTR
|
TMOD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
17110338
|
CFTR
|
MYH9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
22038833
|
ESR1
|
MYH9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25604459
19805454
21182205
|
ESR1
|
FLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25604459
19805454
21182205
|
ACTC
|
DREB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
30890647
30021884
|
DREB
|
FLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
26496610
|
CAZA2
|
ACTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26496610
30890647
|
LIMA1
|
ACTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26496610
30890647
|
FLNA
|
MYH9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
26496610
|
TMOD3
|
ACTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
30890647
|
CAZA2
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27173435
26496610
26186194
28514442
|
CAZA2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26344197
26496610
26186194
28514442
|
CAZA2
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26496610
26638075
26186194
28514442
|
DCTN2
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27173435
26344197
|
DCTN4
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28718761
26344197
|
HDAC6
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ACTR1B
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ACTC
|
CAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
30890647
|
MYH9
|
ACTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26496610
30890647
|
ESR1
|
BTF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18025262
31527615
|
ESR1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11887937
17284441
20935677
28065597
16713569
|
CAP2
|
CAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
8761950
16189514
|
CAPZB
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
27173435
26344197
|
ACTR2
|
CORO1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
EGFR
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ACTR1B
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GNB1
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11742120
11698416
7567982
|
DCTN4
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
27173435
26344197
28718761
26638075
28514442
34079125
|
DCTN4
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
27173435
26344197
28718761
26186194
28514442
22863883
|
ACTR10
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
ACTR2
|
ARPC4
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
ACTR10
|
CAPZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CAPZA2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CAPZB
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
ACTR10
|
CAPZA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CAPZA1
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
CAPZA1
|
CAPZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
ACTR1B
|
DCTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
DCTN1
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CAPZA2
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CAZA2
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
26344197
26496610
26186194
28514442
22863883
|
ACTR10
|
ACTR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ACTR1B
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CAPZA2
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ACTR1B
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CAPZB
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ACTR10
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
DCTN1
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ACTR10
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CAPZA1
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DCTN2
|
DCTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB1
|
GNG12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ACTR3
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ACTR10
|
DCTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ARPC1B
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ACTR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ACTR3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
MYH9
|
ACTR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
12194823
16606694
19349987
21840487
24857661
25712372
|
ACTR3
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
MYH9
|
ACTR3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
12194823
16606694
19349987
21840487
24857661
25712372
|
MYH9
|
ARPC4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
12194823
16606694
19349987
21840487
24857661
25712372
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
EGFR
|
RASA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8647858
16273093
7991458
1850098
17570479
1633149
1385407
|
EGFR
|
HDAC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
20133936
31980649
22896792
20029029
24658140
21151618
25402006
23084749
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
IKBKE
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23816933
20863366
19940156
|
MYH9
|
PPP1CB
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|