Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SNCA GSK3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21985244 8209944
SQSTM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAPN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
VIM CCDC120 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLST NAP1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 INA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
FXR1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 INA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PLEC INA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
POU4F3 INA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8713067 7852360
SQSTM1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA VIM â—¼   COLOCALIZATION 2.0 0.8 intact 16678164 5218597
VIM WEE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BMI1 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 FXR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
PAXX INA â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
VIM GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 ODF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
POU4F1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9448000
POU4F2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9448000
POU4F1 INA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8713067 7852360 10329733
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
SHPRH INA â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
AURKB VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 14762106 14722118 11895474 17081983 19007248 11420699 15676024 12458200 18669648
POU4F2 POU4F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7852360 8662774 8537352 8735273 9223099
SHPRH VIM â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
RAD18 INA â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
RAD18 PPP1CA â—¼   KO_UP_REGULATES ✅ + 1.72 1.72 PKG 28854368
RAD18 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.95 1.94 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368