Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NSD2 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NSD2 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATP5IF1 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RYBP SEPTIN5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCOR1 SEPTIN5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTN1 CAMK2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12223541 5215727
ACTN1 ATXN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
LRRK2 AFF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
AP2M1 CEP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATF7IP PIAS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
NRF1 CAPNS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18234454
CRMP1 CCDC106 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRIM41 CHD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
FLNA CHD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KIF1B CLASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20852589 8079981
COL4A5 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRMP1 EEF1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRMP1 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
FMR1 CYFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11438699 5214235
CYFIP1 FMR1 â—¼   COLOCALIZATION 2.0 0.8 intact 11438699 5214235
DLD TAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RASSF2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF4ENIF1 EIF4E â—¼   COLOCALIZATION 2.0 0.8 intact 5218322 16467844
EIF4E G3BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 6665011 18005740
HNRNPK EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16024782
ESR1 TGFB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12580758 11159847
SAFB ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10707955
ESR2 NCOR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816459 22622808
RYBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SAFB FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
HSPA5 GPRASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2I HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RBMX HNRNPK â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
MATR3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PA2G4 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 LRP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IK SF3B1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SPATS2 LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MATR3 TRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PA2G4 RPS27A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UCHL1 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 20439756
SUMO1 SAFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21527249 25800734
UBE2I SAFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21527249 25800734
YBX1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
TRIM2 UBAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UCHL1 UBAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF451 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DOT1L RPS27A â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
UBE2I ZNF451 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
KIF5A KIF5C â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
MORF4L1 VPS72 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
KIF3A KIF3B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
IK SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPK SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BMI1 CHTOP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 G3BP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MATR3 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33644029 26344197
PCM1 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33644029 26638075
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
COG6 KIF5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COG6 KIF5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COG6 EXOC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FAF1 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28443643 18775313
G3BP1 FMR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26777405 29395067
MATR3 RBMX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29511296
WDR5 TAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32076268 15960975
KIF5A KIF5B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NSD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24101509 31527615
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
ESR2 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21182203 25604459 29509190
PCM1 CEP63 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31413325 26638075 34079125
NCOR1 ESR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29509190 12904255
DYNC1H1 SF3B1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
SUMO1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15576338 19596686
ESR1 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
RBMX FUS â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29884807 27460707 21988832
SUMO1 PIAS3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24654937 15569683 16524884 19217413
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
G3BP1 FAF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 28443643
TBKBP1 TBK1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220020 17568778
RPS27A UBR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EPS15 AP2M1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26186194 28514442 24189400 19380743
PIAS1 ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 11117529 15666801
G3BP2 G3BP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26777405 24981860 29395067 26186194 28514442
HNRNPK RBMX â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
G3BP1 NUFIP2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KIF3A KIF3C â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
PRDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15282304 19746436 10706618
TBK1 TBKBP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CUL3 KLHL12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17543862 32296183 21145461 19995937 25011449 28514442 19295130
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MATR3 FUS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29884807 27731383 27460707 26496610
PA2G4 RPL22 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FBLIM1 FLNA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
OS9 CUL2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 12351678 15652751 15721254
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
ESR2 CLU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
CRMP1 DNAJB11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNAJB11 DRAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNAJB11 FAF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NCOR1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16469706 17400812 12145334 16713569 12738788 21182203 24051437
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 NBPF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
ESR2 NBPF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
PRKAA1 PIAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27256105
PSMD11 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EIF4E EIF4ENIF1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 16467844 5218322
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
BTF3 RPL23A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PSMC3 RPS27A â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP5 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A UCHL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
RPS27A WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
PA2G4 RPL23A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
EIF4E EIF4ENIF1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MAEA RANBP9 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL22 RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23A RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMC3 PSMD11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CAMK2A GFPT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17941647
SMARCA4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11532957 14964309
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PRKCB EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8662663 12897141 9155017 11723111 95301551 11463832 9878069
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21486948 23892277
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21233487
FBLIM1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24165133 12679033
NRF1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16886907 9302255 9328468 11058604 15175277 24250222 18782566 16500891
PRKAA1 GBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 33208442 18063581 28389568
PRKAA1 GFPT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19170765 17941647
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
KIF3A KIF3B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
SMARCA1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23609547 24285714 20015969 17023429
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593