Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHD2 H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRPF8 H2BC12L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SUMO1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16478998
TRIM41 CHD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SMC1A CHD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FLNA CHD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
DHX9 SF3B1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ESR1 DHX9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19805454 21182205 20348541
ESR1 SRPK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
PARP1 DDB2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
ESR1 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
SSRP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
SUMO1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19779455 15561718 23871147 15576338 19596686
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
SUMO1 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
SSRP1 SUPT16H â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PRPF8 SNRNP200 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
LEO1 SUPT16H â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PRPF8 SF3B1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LEO1 SSRP1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SF3B1 SNRNP200 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PRPF8 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
DDB2 CHD2 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368