Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PARP2 PCCA â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
FHIP2A PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
CTNNB1 PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
DDB2 PCCB â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ICMT PCCA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYRM PCCA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LAMP3 PCCA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACSM5 PCCA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PCCA TTC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NHEJ1 PCCB â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
SEC24C SEC24D â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PCCA PCCB â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
XRCC4 PCCA â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
PCCB PCCA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 20725044 28514442 11749052
RECQL4 PCCA â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
PCCA PCCB â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PCCA RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PCCB RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
PCCA HLCS â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
PCCB HLCS â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
HLCS MCCC2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
XRCC4 ACO1 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
DDB2 ACO1 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
NHEJ1 PCCA â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
DDB2 PCCA â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
NHEJ1 LGALS3 â—¼   KO_UP_REGULATES ✅ + 2.3 2.3 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368