Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TPR PCCB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATM DYRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19965871
FXR1 PCCB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PCCB CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10094392 5211308
FXR1 CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DDB2 PCCB â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
NDUS7 PCCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 31536960
NHEJ1 PCCB â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
PCCA PCCB â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PCCB PCCA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 20725044 28514442 11749052
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
EXO1 PCCB â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
PCCA PCCB â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PCCA RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PCCB RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ERCC6 PCCB â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
PCCA HLCS â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
PCCB HLCS â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
PRDM1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12626569 11279146 10713181 12032779
NHEJ1 PCCA â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
DDB2 PCCA â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
ATM PCCB â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368