Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GSN JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN WNT7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IGFBP4 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SPRED1 IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 IGFBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
WNT1 SOX9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18495817
PAPPA2 IGFBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9883900 11264294
IGFBP5 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9497324 16189514
WNT9A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
FGFR3 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WNT7A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857724 15578921
WNT10B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
KLF11 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531587 15024015
SP1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12683994 18064385
IGFBP4 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9722589 16189514
IGFBP1 IGF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605652103 16924115
ATXN3 IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 IGFBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
FGFR3 IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOR1A IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IGFBP4 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT IGFBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IGFBP4 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAPPA IGFBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9751498 12241545
ESR1 IGFBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
FGFR3 WNT7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 WNT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20126574
IGFBP1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WNT1 LRP6 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 21078818
LRP6 WNT1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
WNT7A WNT7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
ESR1 KDM1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 17289570 31527615
WNT4 WNT7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
WNT3A WNT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LRP6 WNT3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
IGF1R IGF2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
LRP6 WNT3A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19910923 12897152 14739301 33961781 22726442 21944579
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
WNT1 LRP6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11448771 11029007
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
ESR1 GSN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
JUN PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14684847 12446585
WNT2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23209147 15578921 32196115
WNT9B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20093360
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 PTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15890770 12810570 15001549
SP1 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10558886 10471823 11802722
SP1 IGFBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10342835
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
IGFBP1 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10810289 22578544
IGF2 IGFBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10810289 22578544
WT1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9076342 7791758
IGFBP1 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10350456 22578544
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
IGFBP1 IGFBP4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
IGF1 IGFBP5 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
IGF1 IGFBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IGF1 IGFBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
WNT1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21078818 11029007 10557084 23331499 29444668 21071413 11448771 18988627
IGFBP5 PAPPA â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFBP5 PAPPA2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFBP5 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9497324 1147105 15642270
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8206951 19920132 19103645 8439327
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
LRP6 WNT8A â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
LRP6 WNT8B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT3A LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23400998 21078818 19339249 12897152 14739301 24265322 16890161 22726442 19910923 15578921 20093360 22491013 18772438 21944579
WNT3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18528331 15578921
SP1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9329821 8544848 2849945
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
SP1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12554796 12706304 15019994 20087433 10894148
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 IGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8405433 11327698 11165040 9620554 9610618 12804776 11336542 10606246
IGF2 IGF1R â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 1310594 3019338 2839228 1845984 2969892 3011795 3013881 22140443 19139090 16981855
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
IGF2 IGF1R â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11237532 15003992 17145802 17600088 24668028
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
WT1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8390684 7497000 16698800 15345673 11001824 9076342 12444079 10499530 11896622 7791758
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
IGF2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9972281 23331499 22810696 20980691 14604834 11867533
WT1 IGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 1323141 7553624 7862533 7535092 9927198 8196623 8634146 10606246 9460996 8119964
IGF2 PAPPA â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF2 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
ESR1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19920132 17166846 22739988 10750020 11566442 20372799 8206951 9014838 24914937 11457856
IGF1 PAPPA â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF1 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGFBP4 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9722589 7683646 16924115 15642270
IGFBP4 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGFBP4 PAPPA â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
PGR IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12489992 9178756 10459849 15987820 11117526
WT1 WNT4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22465478 12082525 20161747 21871842