Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
DKK4 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 29925589
GLI1 FRZB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16328026 17035233
SFRP2 FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28840375
RSPO3 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 WNT9B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
WNT9B LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23209147 15578921
ZMYM3 WNT9B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DKK4 LRP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
WNT9B GRP78 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26186194 30021884
LRP6 FZD8 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15908424 11448771 11029007
SOST LRP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 15908424 21471202
LRP5 DKK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19158955 18044981 17047023
DKK1 WNT9B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17804805 11448771 22807036
DKK4 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29925589
WNT9B FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30978219 25892522 28733458
FZD5 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12857724 18077588
GLI1 SFRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16328026 17035233 19930158
SOST LRP6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21944579 15908424 28514442 21471202
WNT9B LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20093360
DKK1 LRP6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
LRP6 SOST â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
DKK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 23331499 19339249 21071413 12527209 21944579 11448771 21984209 11357136 11516963 18988627 29925589
DKK1 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19101658 11448771 18786602 16307379 11516963
LRP6 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
LRP6 FZD2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
SFRP1 FZD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 6172602
SFRP1 FZD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10347172
FZD8 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11448771 21078818 11029007 20093360
FZD8 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11448771 21078818
GLI1 SFRP1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
GLI3 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12435627 14723851 10075717 16571352 19667090
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
SOST LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22696217 15778503 21944579 15908424
SOST LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22696217 15778503 21944579 15908424
RSPO1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17804805 17976036 18400942
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368