Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAPPA2 IGFBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9883900 11264294
IGFBP5 IGFALS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9786878 9497324
IGFBP5 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9497324 16189514
IGFBP4 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9722589 16189514
IGFBP3 IGFALS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9497324 9446566
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
IGF2 IGFBP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IGFBP3 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22578544 10407151 11749962
IGF1 IGFBP5 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
IGF1 IGFBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IGFBP5 IGFALS â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 8781553 11788658 7519608 10614670 11316783 9497324 7683646 10810289 7689487 12379487 9786878 12466191 15126567 17047378
IGFBP5 PAPPA2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFBP5 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9497324 1147105 15642270
IGF2 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
IGF2 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF1 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
IGFBP4 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9722589 7683646 16924115 15642270
IGFBP3 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
IGFBP4 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGFALS PAPPA2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292