Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IGFBP5 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9497324 16189514
IGFBP3 IGFALS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9497324 9446566
IGFBP5 IGFALS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9786878 9497324
PAPPA2 IGFBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9883900 11264294
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
IGF2 IGFBP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IGFBP3 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22578544 10407151 11749962
KLK3 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7538844 10218588
MMP1 MMP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 8194591 7981201 8015608
IGF1 IGFBP5 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PLG IGFBP3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7527330 17047378 8964575 11739083 7588299 8894645 12466191 12379487 10990447
PLG IGF1 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7527330 17047378 8964575 11739083 7588299 8894645 12466191 12379487 10990447
PLG IGF2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7527330 17047378 8964575 11739083 7588299 8894645 12466191 12379487 10990447
PLG IGFALS â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7527330 17047378 8964575 11739083 7588299 8894645 12466191 12379487 10990447
F2 IGFBP3 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 8817670 11739083 12379487 12466191 17047378
F2 IGFALS â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 8817670 11739083 12379487 12466191 17047378
F2 IGF2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 8817670 11739083 12379487 12466191 17047378
F2 IGF1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 8817670 11739083 12379487 12466191 17047378
MMP1 IGF1 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF1 PAPPA â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF1 MMP2 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF1 KLK3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
IGF1 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
IGFBP5 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9497324 1147105 15642270
IGF2 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
IGF2 KLK3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
IGF2 PAPPA2 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF2 MMP2 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF2 PAPPA â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 10077652 10898936 12904166 11158056 17249697 17312271 12379487 12241545 12466191 17047378
IGF2 MMP1 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGFALS PAPPA2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFALS PAPPA â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFBP3 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
IGFBP5 IGFALS â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 8781553 11788658 7519608 10614670 11316783 9497324 7683646 10810289 7689487 12379487 9786878 12466191 15126567 17047378
MMP2 IGFALS â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
KLK3 IGFALS â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
MMP1 IGFALS â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
MMP1 IGFBP3 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
MMP2 IGFBP3 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
KLK3 IGFBP3 â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 8817670 7538844 11751371 7525824 10218588 12379487 7525634 12466191 1383255 17047378
IGFBP5 PAPPA2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292
IGFBP5 PAPPA â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 11788658 17047378 11606061 12379487 11264294 12466191 11522292