Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15752709 18064385
IMMT MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
SH3KBP1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 ZDHHC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28775165
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
GSK3B YBX1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16198352 5217974
MAP4 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FLNB NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
NR1I3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15268900 21389059
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
MAP4 ENO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2AC21 MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC21 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIK3R1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
VCAM1 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
VCAM1 IMMT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CYLD MAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31067453 31762063
ESR1 MAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
GRP78 MAP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 26496610
MAP4 FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19293945 26344197
VCAM1 FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ESR1 IMMT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 19805454 31527615
LDLR GRP78 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16257961 10906332
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ULK1 RB1CC1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8428476 23392225
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
BMI1 IMMT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 16713569 16169070 34316702
HDAC6 CYLD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19893491 20593489
MAP1LC3A ULK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POT1 TERF1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
GSK3B MAP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ULK1 RB1CC1 â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 19597335
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ABCE1 RPS14 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
RB1CC1 ULK1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK1 TERF1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 14551205 15279786 17303408 17660363 18414028 18590585 18625707 22624377 7575488
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
GSK3B CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9832503 17359287
CDK1 MAP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19691289 15216889 10791892 20068231 17570479 11683421 19664995 9398320 19415658
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
NCK1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
TP53 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10321740 19763735 21057544 18661553
IL7R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9233603 7522165
ESR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11029009 11689445 16169518 23065768 16713569
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 MAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10521394 10446979 19411072 10990460 8956998
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
NCK1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GSK3B DCX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 21159948
FYCO1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20562859
GSK3B H1-5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19609548 19136008
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ULK1 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20562859 19225151 23392225 19597335 25686248 26118643 19211835
MARK1 MAP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 19651622 19415658 20058876 17081983 20166139 18767875 20068231 18707149 18452278 17693683 8631898 18212344 10542369 18669648