ARAF
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
NFE2L2
|
DDIT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22691366
14978030
|
DDIT3
|
ATF3
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
F2R
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
ESR1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23250869
22430216
|
AR
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14619959
20610535
|
FGF2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9490736
12750158
|
RUNX1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29958106
|
MYC
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9973255
15192039
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
JUN
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8375573
8380380
|
ESR1
|
CRH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8408641
|
CALM1
|
MYH9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
3079756
3839510
|
CALM1
|
MYH14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
3079756
3839510
|
AR
|
CALM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16619263
20610535
|
CALM1
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16258073
10075700
|
JUN
|
GAST
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16139800
9142914
|
AVP
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9756892
8621513
|
RXFP3
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CHRM3
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ADORA2A
|
GNAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8995267
6162091
|
MC4R
|
GNAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
20371771
|
GNAS
|
ADCY4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9228084
21406690
|
GNAS
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9228084
21406690
|
RUNX1
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
15084276
18003603
|
NFE2L2
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21127061
27211851
|
MECOM
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1119229109
22308434
|
NCOA3
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16877447
16860316
|
JUN
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
JUN
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8382609
22243239
|
JUN
|
LHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10787426
16627584
|
JUN
|
LBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15114678
|
KLF8
|
CTBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17671186
19798104
|
KLF8
|
CTBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17671186
19798104
|
KLF3
|
KLF8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18687676
|
RARA
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0709483104
18048326
|
NFE2L2
|
ATF3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24509533
19864258
|
ESR1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24641954
20623181
|
AR
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11690559
20610535
|
GRHL3
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11373277
16036112
|
RUNX1
|
MECOM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22689058
|
PGR
|
ADCYAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11027674
10537148
|
ESR1
|
GNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19170076
18414489
|
GNAQ
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219925
17498700
|
ADRA1B
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9481484
31160049
|
ADRA1A
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
1334487
|
GRPR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
17251915
|
CRHR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10598591
22869609
|
CHRM3
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
7629074
|
HTR6
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12650852
31160049
|
PTAFR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8576109
31160049
|
HTR2B
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11916537
31160049
|
S1PR3
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10488065
31160049
|
GNAQ
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB2
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
WT1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18708366
16087727
|
ESR1
|
AVP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11089536
|
ESR1
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18313050
19861308
|
ESR1
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9259323
8625613
|
ESR1
|
WT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18708366
16087727
|
AR
|
GRP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19117998
17079466
|
AR
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12069693
20610535
|
AR
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
16987234
|
AR
|
F2R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
15629896
|
AR
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16376459
20610535
|
AR
|
ADRA1D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
16964290
|
AR
|
ADRB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9855630
20610535
|
AR
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15629896
|
AR
|
MMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16888681
|
PLCB2
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
RARA
|
TSHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9296372
7835286
|
TTF1
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12730191
18395010
|
IL7
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8709637
7489741
|
STAT5A
|
IL7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12811842
18042802
|
GATA4
|
AGTR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9207128
10579051
|
SRF
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11003651
11158291
|
SRF
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12654640
|
GCG
|
GIPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0706404104
17715056
|
PGR
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15046957
7113584
|
NPBWR1
|
NPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12719537
7590751
|
KLF3
|
KCNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
NMB
|
GRPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1655761
8383682
|
CTSG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10978167
|
NKX2-1
|
TTF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11046146
9588495
|
APLNR
|
APLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8294032
9792798
|
NPFF
|
NPFFR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11024015
9224703
|
GATA4
|
NKX2-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
JUN
|
ATF3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
10327051
6546308
|
VIP
|
VIPR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
11027527
15247290
23597562
807467
|
AGT
|
AGTR2
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
16597412
|
MYC
|
CTBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
RUNX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
MYC
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
20232342
|
ESR1
|
CTBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
RUNX1
|
CTBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17635584
30585266
|
ESR1
|
MYH14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21182205
25604459
|
NPB
|
ECE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ADORA1
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
ESR1
|
PGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
CALCRL
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
CALCRL
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
GNG2
|
PTH1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
GLP1R
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
CALCRL
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
GLP1R
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
BRAF
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
GNAQ
|
VIPR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11981043
11812005
|
AGT
|
AGTR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
ESR1
|
MYH9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21182205
19805454
25604459
|
CALM1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
GLP1R
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
GNB1
|
PTH1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
ESR1
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9717844
25303530
25604459
|
TAC1
|
TACR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
JUN
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CACNA1S
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALCA
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ARAF
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ATF3
|
DDIT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
JUN
|
RUNX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11641401
11274169
|
BBS4
|
BBS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17574030
28514442
22500027
33961781
27173435
19081074
|
GATA4
|
SRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11158291
11003651
|
CALCRL
|
RAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
JUN
|
DDIT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10523647
23661758
|
JUN
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17317669
11477071
16713569
23747343
|
NCOA3
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25303530
16713569
17475621
9346901
12665583
19144644
15604093
9192892
20413580
16456540
|
NCOA3
|
PGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
NCOA3
|
RARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BRAF
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
25241761
31980649
28628118
17979178
20130576
34017080
33961781
28205554
|
ATF3
|
DDIT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
31467278
23661758
20211142
26264872
29997244
32814053
33961781
8622660
20102225
27107012
|
JUN
|
DDIT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19299913
22622069
12069855
|
BRAF
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
MAPK1
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11585926
|
STAT5A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17927978
12048235
12967477
|
WT1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15286719
17634147
20842112
|
MYC
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18413597
10500217
18414489
|
MYC
|
AVP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ADCY9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
AR
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16446741
|
CALM1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2022671
7685187
8417150
|
ESR1
|
C3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10418989
8961270
17478088
|
CTSG
|
C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24315997
1861080
|
GNAS
|
ADORA2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
GNAS
|
ADORA2A
|
â—¼ SHARES_COMPLEX
|
|
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
GNB1
|
GNAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15782186
16189514
26186194
|
GNAS
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
|
GNAS
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
GNAS
|
ADCY9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
GNAS
|
ADCY7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
ADORA2A
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
17371980
17909080
18758473
|
JUN
|
PGR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14684847
12446585
|
JUN
|
NTS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7791794
7476995
|
CTBP2
|
KLF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
35140242
10756197
|
KLF3
|
CTBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9724649
35140242
32296183
12556451
|
NKX2-1
|
ADCYAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19285000
17464199
12122016
|
ESR1
|
ADCYAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
AGTR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17498700
31160049
11313903
|
TSHR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17891229
32698392
8188646
|
NCOA3
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26153859
20392877
15383283
14766010
25728767
21182203
15145444
18484708
11376110
14966289
9346901
20181721
26166704
16331275
28844863
11389589
11050174
12630920
19491275
17158759
23403292
12714702
17646391
9192892
11353774
16923966
18645020
16713569
30418174
10490106
9765300
12554772
26487511
|
ESR1
|
GRIK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ESR1
|
LHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9453238
16055746
2909546
|
NCOA3
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10965917
17108143
19305643
|
AR
|
CDH11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20191612
20610535
|
AGT
|
CTSG
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6807977
9570564
20889553
|
CTSG
|
AGT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11747312
10899625
|
STAT5A
|
GHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12488452
15840840
17412814
|
TSHB
|
TSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8188646
2558651
12045258
|
VIP
|
VIPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7811244
8390245
3899557
|
PGR
|
RLN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15149733
|
PGR
|
RLN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15149733
|
LHB
|
LHCGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1922095
8702611
2244890
|
PMCH
|
MCHR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10421368
11562423
10421367
|
ATF3
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
ADM
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
ESR1
|
NCOA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
ADCYAP1
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ADCY9
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ADCYAP1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA1C
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
GNAS
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATF3
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8649793
23661758
26496610
10327051
8622660
1827203
25609649
20102225
14667575
20304822
|
GH1
|
GHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
GNAS
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
AR
|
NCOA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BBS1
|
BBS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ARAF
|
PPP1CC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
14.0
|
1.0
|
Reactome
|
16294014
21779496
24211266
27264673
19684605
16041367
24347342
16630891
28666118
12932319
11756411
25907612
14530258
28289718
|
MYC
|
DDIT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15021909
18483244
|
ATF3
|
DDIT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9343434
14729979
22753726
10085237
|
NFE2L2
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19454702
23708697
17467702
21808062
|
MYC
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22789855
21933022
16596619
23617883
8013639
20144848
|
MAPK1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9804779
25241761
18775330
10194762
8226933
10996427
9604935
8388392
12091337
|
MAPK1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8072547
11313929
15378002
12531896
12853483
23720779
9662434
1496019
17570479
1922387
11278277
11739718
16023596
20086174
25557171
7737130
26755651
8224842
14676207
17920329
25201974
9022811
22327296
18650425
8137421
18443042
12881422
18572021
17001009
33767435
7744008
23616010
26745678
14617628
11432833
16819515
22606284
12040039
|
MAPK1
|
PGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8702648
17173941
18202149
10628747
15798179
17717077
12529413
15212693
10655479
11110801
|
MAPK1
|
RUNX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16046550
17015473
|
MAPK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15655247
10949034
15528270
18372406
15461668
12118371
12466266
7495695
17615152
15059947
16076840
7491495
12093745
10409727
9528769
7838153
|
MAPK1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10551811
17081983
8386367
17251036
91332050
17570479
1748630
7957875
27167001
15212693
1651323
15210690
|
MAPK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
16508002
19710016
19933846
15664191
29335436
8621729
|
MAPK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18511414
9725910
10318905
|
JUN
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
11274345
11929833
11955436
11967263
12051714
15001769
15576399
15768032
15806138
16007074
16039586
16169192
16510874
17050667
17143292
17291450
17439715
17936032
18347071
18627596
19619488
19623618
20006983
20122174
20530697
20705860
20920541
21285352
21767405
22290435
22705350
22761862
23306204
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
KLF8
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
15576399
16039586
17143292
17306568
17666529
17671186
17936032
19619488
19623618
20705860
21151179
21285352
22290435
22761862
23343194
24023259
25730849
7542250
8666229
|
JUN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835891
8276360
1774959
2498162
21607323
20410304
14523011
18037408
|
PGR
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8701093
9408078
22396492
9305935
22892083
10651641
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
JUN
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
15806138
16510874
22290435
18627596
19623618
11929833
23343194
15768032
22761862
17050667
16039586
20122174
17291450
20920541
17143292
20006983
17439715
15576399
21767405
23306204
8545107
22705350
18347071
16007074
16169192
21285352
20530697
19619488
11274345
|
ESR1
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18597742
18404132
8408641
17947358
9408232
15126558
12161509
15564578
|
CRH
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8536644
8243338
23504413
11123370
|
CRH
|
CRHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
8612563
8536644
19124613
7477349
11416224
9178757
7692441
9851694
20966082
11123370
9326293
10598591
18801728
|
CALM1
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
CALM1
|
GRM7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15494036
10488094
11953448
12021391
|
NPVF
|
NPFFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12242085
12421602
29106375
|
GCG
|
GLP1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
18248821
11116211
15528268
7937318
8404634
|
C3
|
C3AR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8702752
11342658
8765043
20527893
9476119
|
MYH9
|
MYH14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
ROCK1
|
MYH9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10652353
11698448
12194823
12778124
19349987
27785353
|
GCG
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15569269
8405712
19859570
17306374
17900700
|
ADORA2B
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
ADORA2B
|
GNAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
ADRB2
|
GNAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12036966
15782186
23798571
6149763
|
GNAS
|
ADCY2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9228084
9395396
1719547
9268375
21406690
|
GNAS
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9228084
6935665
210183
17652154
2022671
21406690
32196115
|
GNAS
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9228084
9748257
9268375
21406690
|
JUN
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20006311
22123848
14734615
15187132
11943142
20304822
17556653
1314139
17105733
22413812
19265145
11801649
16713974
7759501
12836278
15522880
12626576
9558063
8756632
18641343
22351517
|
STAT5A
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12759422
7875295
7796811
15528362
9831114
|
ATF3
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
20203264
24317040
17785797
24951825
20351107
22105779
16688168
18942706
17766920
|
AR
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12237244
8824277
19074897
11049111
17374439
11410519
20610535
19363165
|
JUN
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
26513016
10542237
21069809
15389813
15158360
20225236
12667961
20371366
20511231
20862675
8453101
10202034
18502099
10037779
8830832
19687301
21098092
25567680
20351184
17341596
11120852
21312239
24676671
|
ESR1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11477071
17963131
10037443
16679312
|
JUN
|
ATF3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8576171
21304988
14667575
10979959
22870894
|
JUN
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9456251
10913304
10559225
11281649
11551904
23485603
23331079
|
JUN
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15557322
15790955
20339243
21467818
19880446
14990565
16491116
17360982
|
JUN
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19268464
15212943
14767528
19940138
11414701
15777790
20353950
17116726
16000878
|
ESR1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
AR
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11577103
11518798
9211894
8798722
16713569
9591784
17721441
|
ATF3
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10327051
25609649
1827203
14667575
20102225
23661758
8622660
20304822
8649793
|
JUN
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11477071
17317669
16713569
|
JUN
|
ATF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10327051
25609649
1827203
14667575
20102225
23661758
8622660
20304822
8649793
|
KLF8
|
CTBP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10756197
16713569
|
NFE2L2
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24466341
17640564
18588981
15655294
22951256
|
PLG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10978167
|
ESR1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18234909
11522780
9869301
10428965
12761896
|
CALCB
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2177866
8626685
2985435
6609312
14722252
|
CALCRL
|
ADM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
CALCA
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17145710
11693189
8626685
3001670
16293613
12234182
14668209
23597562
10347248
9620797
|
ADM2
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21658025
14615490
|
ADM
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11693189
10347248
9620797
|
CALCB
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11693189
8626685
3001670
12196113
12234182
14668209
10347248
9620797
|
ADCYAP1
|
VIPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
8791009
16930633
11897681
12429744
12488235
11931347
9928018
|
ADCYAP1
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
8703026
16930633
12488235
10583729
11931347
21350482
10100920
17470806
8253796
|
ADORA2B
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
GNB1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ESR1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11689445
27288742
11369763
25587652
|
PDYN
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9544801
16415903
11786497
10215864
|
ADORA2B
|
GNG2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
GNB1
|
GNG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GNG2
|
GNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
PDYN
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9544801
16415903
11786497
10215864
|
ADORA2B
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
ADORA2B
|
GNB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
2553705
3127824
9651336
12106601
12860470
|
PDYN
|
GNAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9544801
16415903
11786497
10215864
|
BDKRB1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12130679
11379050
31160049
11713280
|
BRAF
|
PPP1CC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
14.0
|
1.0
|
Reactome
|
16294014
21779496
24211266
27264673
19684605
16041367
24347342
16630891
28666118
12932319
11756411
25907612
14530258
28289718
|
ZNF217
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
15986123
17463000
23723241
15345050
21445275
24973012
17666587
11103799
|
STAT5A
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11731618
22201800
11682624
11682625
|
ESR1
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8300756
8912864
8732679
11038749
15831516
15870697
10076999
9626663
18414489
|
ESR1
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19935720
19376833
18414489
|
ESR1
|
PGR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
12829318
12554765
12446585
11000528
15019994
8043503
23027806
9058379
9717846
18414489
12706304
10835496
16293641
18784357
12761896
8145766
22543272
15743834
8530508
10894148
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|
PGR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
22396492
16168121
12612073
11000528
18988627
26153859
|
ESR1
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
17641689
15831516
9717844
9841885
|
AR
|
LHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11518799
20610535
16077169
|
AR
|
MMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18612129
16888681
20610535
|
NCOA3
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
14966121
11747336
15563469
16713569
10965917
21047772
|
SRF
|
ACTA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18337547
12505862
17303098
19269978
19608972
20093628
15576380
12530967
20016221
24446247
22461426
14970199
15269336
|
ZNF217
|
NCOA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
15986123
17463000
23723241
15345050
21445275
24973012
17666587
11103799
|
SRF
|
ACTG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16814806
12450213
19797053
24106278
24802754
18296735
12890560
18496575
9473329
10993896
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
AGT
|
AGTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
2775266
21464395
8315512
21542804
17138938
8185599
15930094
9797979
8242249
7850406
|
WT1
|
GATA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9815658
11207191
18445271
11278460
|
NKX2-5
|
GATA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19479054
15653675
16137232
|
TAC1
|
TACR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
12954451
7682062
9190866
8925404
11786503
7961636
11137709
10189055
7534932
23597562
|
CALCA
|
RAMP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
14722252
11693189
11033437
12565884
30139742
15692146
10347248
|
C5
|
C5AR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9881961
11773063
9553099
15661745
10602324
1847994
|
GH2
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2387255
1955498
|
GH1
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
2825030
8943276
17500058
1549776
9353194
26713839
1935820
31279174
9030599
23331499
7862673
7691587
19927328
10551877
21889455
9571026
3349036
2387255
31100495
29145629
24280222
24243840
|
RAMP3
|
ADM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
ADM
|
RAMP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11693189
27391260
12565884
30139742
15692146
10347248
14712479
|
STAT5A
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10674400
7744007
8732682
11092411
12683938
18388193
22698918
19819986
22166977
11564677
14532269
17412814
12970402
10373481
15677453
10803577
|
PTH1R
|
PTH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
12559132
3616618
6950381
12098667
8732687
8386612
8397094
8770894
8082781
7797535
|
PTH
|
PTH1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18981475
9108031
12947048
29444827
19674967
|
PTH2
|
PTH1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
10854439
11159842
|
NPB
|
NPBWR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12118011
12401809
|
UCN2
|
CRHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15450949
|
UCN2
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
11226328
11416224
11329063
15450949
|
TTF1
|
TSHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10807057
8813723
8145764
7997232
15929662
7654187
7565801
|
NKX2-1
|
TSHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8813723
8145764
15929662
7828540
7565801
|
TSHB
|
TSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
2558651
20181794
12045258
15571461
|
KNG1
|
BDKRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18127230
3366244
8063797
1314587
|
KNG1
|
BDKRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18127230
3366244
8063797
1314587
|
KNG1
|
BDKRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9313952
8856107
8735629
9111052
8063797
10422787
|
KNG1
|
BDKRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9203620
8063797
8302267
28966616
|
NMS
|
NMUR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15635449
29288685
|
VIP
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
16930633
12488235
10583729
11931347
|
VIP
|
VIPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
92.0
|
1.0
|
Omnipath
|
9437714
8791009
11027527
16930633
9152366
10655511
15247290
8390245
9928018
10570056
807467
9726637
9454823
10801840
10655512
11897681
12488235
11931347
8074647
|
NPW
|
NPBWR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12130646
12401809
|
KCNIP3
|
PDYN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21167062
21660149
18507845
12667101
15181011
|
INSL5
|
RXFP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
25761609
15525639
18582868
|
GHRH
|
VIPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8791009
10655511
|
NMB
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
1655761
1720612
10454496
7838118
19463875
21729729
|
GRP
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
17251915
1720612
10454496
7838118
19463875
21729729
|
CORT
|
SSTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
15333679
11011067
9125122
9650799
9205124
10598788
|
CORT
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12161511
1122773711227730
11227737
|
RAMP3
|
ADM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
CALCB
|
RAMP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11693189
26423127
15692146
10347248
|
ADM2
|
RAMP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
27013657
21658025
20596793
30139742
|
AVP
|
AVPR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2991279
4065330
8106369
7929452
|
AVP
|
AVPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2991279
4065330
8106369
7929452
|
AVP
|
AVPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
15084136
9334232
10519430
12446593
10780976
9884074
1560825
9322919
9264324
9459574
9864265
8106369
10866830
|
AVP
|
AVPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
15084136
10519430
12446593
10780976
9884074
1560825
9322919
11012895
9264324
7774575
11857925
9459574
9864265
|
AVP
|
AVPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
15084136
10519430
12446593
10780976
9884074
9322919
9264324
9459574
16158071
7929452
9864265
|
UCN3
|
CRHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11416224
|
KISS1
|
KISS1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
15665093
11457843
11385580
12944565
|
LHB
|
LHCGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
3470775
10446903
12727981
1922095
|
APLN
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10617103
12939143
11336787
10802050
10777510
12603839
16189514
9792798
15341513
|
GRP
|
BRS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11112777
|
UCN3
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
11416224
11329063
15450949
|
APELA
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
29357134
25995451
25639753
29079036
28137936
26611206
28663440
24316148
|
PMCH
|
MCHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
11478907
10421368
10421367
11375253
11839762
|
NPFF
|
NPFFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
10851242
12421602
11024015
12609745
11325787
|
RLN2
|
RXFP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
11809971
12506116
22973049
15649866
18434306
|
RLN2
|
RXFP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20159943
24641548
32103204
|
RLN1
|
RXFP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11809971
25761609
16411781
|