Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ITGB1 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0807543105 19168626
ITGB1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19168626
VLDLR DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10380922 16046028
RELN DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11137154 15110774
ABL1 SNX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
APC LRP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19116273 0807594106
VLDLR APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19116273 0807594106
LRPAP1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNX17 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRIN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ITGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
HIC1 VLDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24076391
KRT8 LRP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DAB1 VLDLR â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
APP DAB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SNX17 VLDLR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12169628
MAPK8IP1 MAPK8IP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LRP8 JIP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10827199 10827173
LRP8 JIP2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10827199 10827173
DAB2 FGR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12473651 16713569
DAB1 CRKL â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15110774 15062102
DAB1 LRP8 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ABL1 RAD51 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
APBA2 APBA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
RELN VLDLR â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
LRP8 RELN â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
LRP8 AMRP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 12899622 20223215 16101684 10231386 28514442
LRP8 APOE â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8626535 32814053 12950167 12167620
LRP8 DLG4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10827173 16332682
LRPAP1 VLDLR â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ABL1 CRKL â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CRKL ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8524328 16955467 8978305 19823681 16443220 7926767 7493940 18835194 9710592 24412932 14604282 22286129 9820532
VLDLR AMRP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7592875 12899622 20223215 10571241 8083232 28514442
FGR ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
RELN ITGA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10939329
MAPK8IP2 MAPK8IP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10629060 10490659
APP MAPK8IP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
APBA2 APP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
SNX17 LRP8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12169628 24705369
JIP1 JIP2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 10629060 10490659
APBA1 APP â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ITGB1 ITGB1BP1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
APBB1 APP â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DLG4 GRIN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CRKL KDR â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL RAPGEF1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL KDR â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
ABL1 CRKL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
CRKL RAPGEF1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
ABL1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 8978305 22581121 20841568 10837221 18768933 7493940 9710592 16955467 8524328 23331499 21199784 18794134 10592173 21051857 7926767 16443220 18835194 24165979 26500649 18809728 15459660 26192618 24412932 9053848 22286129 8083188 14604282 21435002 9820532 19823681
CRKL RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 8943292 10753869 8978305 16443220 11466412 8621483 9129019 10907644 18835194 10592173 9374471 10926930 9311917 10339478 11167825 12671687 9344843 9820532
ABL1 RAPGEF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 23331499 26546517 9461559 15279774 15033353 19427856 11684015 19285032 20841568 15330855 15212693 10212258 12359302
ABL1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20110615 15031292 18922798 26255939 11279131 22506131 20841568
ABL1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11279131 20841568
ABL1 RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16443220 20581864 20841568 17474147
APP APBA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12196555 12972431 11517249 9890987
DAB2 APC â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 15518237 17318175 19561074 19581931 20460648 21304492 21498506
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
APOE VLDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19116273 11278667 12167620 12870663 16504486
APOE LRP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626535 12167620 12950167 16504486
DLG4 GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12068077 9009191 14732708 11937501 11506858 9502803 16767099 15030493
ITGB1BP1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11741908 19118207 11919189 16189514 9281591
RELN ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10725376 10939329
RELN LRP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12670700 12899622 10571240 23951306 12167620 28446613 16504486
LRPAP1 VLDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7592875 8083232 10571241 20223215
RELN VLDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10571240 10571241 14724251 11278667 16504486