Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
KRAS BCL2L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16483930 29311131
HIF1A BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17558861 19211554
FUS BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
DVL2 CSNK1E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CSNK1E CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20940130
GABBR1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DVL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
F2RL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
APP GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12485888 5215996
GRB2 SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NR1H4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CCKBR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 TFAP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRB2 ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
LYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYN PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 16713446
SSRP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23613959 9687513
CALM1 ACTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14622581 10373510
CALM1 CAMK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8340352 20668654
CALM1 ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16258073 10075700
CALM1 CAMK2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20668654
CALM1 ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6455424 1332771
FYN CCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EFNB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTG1 EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTG1 EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ADRA2C GNAO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1349607 31160049
DVL2 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
YES1 CSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
CCKBR FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ATXN1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
ABL2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FYN CSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
FYN C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15886098 5217726
HRAS EFNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
HRAS EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
HRAS EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
ERBB3 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
FZD2 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23151663 19388021
DVL2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
CREBBP ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
CSF1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
SP3 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8407965 8981362
FGFR3 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DVL2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
SRC F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
SRC ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16781829 10625617
LNX1 SRC â—¼   COLOCALIZATION 2.0 0.8 intact 6504434 17936276
SRC CACNA1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17942635 12850569
SRC F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17474147
EFNB1 TIAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17440041 14988728
GRIN1 TIAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17440041 14988728
EFNB2 TIAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17440041 14988728
TIAM1 EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17440041 14988728
TIAM1 GRIN2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17440041 14988728
ELK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BRAF PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
TFAP2A PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12269829
PRKCA GLRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8294452 17570479
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
TFAP2A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10652362
GNA14 GNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNB1 GNAI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7102203 16782902
F2RL1 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
DRD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAMK2A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRIN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DVL3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FPR2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRNA7 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CACNA1C ACTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ATXN2L ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DCTN1 DCTN5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
LNX1 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYP2C8 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
GRIN2B CAMK2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8294337 19453375
CAMK2A GRIN2B â—¼   COLOCALIZATION 2.0 0.8 intact 8294337 19453375
DRD2 GNAO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1445393 31160049
KLF11 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PDLIM5 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADCY6 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FFAR2 GNAO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12711604 31160049
EGR3 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22035109 16901909
TFAP2A ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18358466 11278550
NRG1 ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10768865 23365119
ERBB4 DLG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212340 10725395
ERBB4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212340 10725395
GRIN1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR1I3 CYP2C8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15933212 15155833
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
DRD4 ADRA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22723743 1001347
DRD4 ADRA1B â—¼   PROXIMITY 2.0 0.8 intact 22723743 1001347
SP3 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11578973 20462637
BDKRB2 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TFAP2A ADRA2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15037199
F2RL1 ATP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GNA14 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
C8B C8G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DLG3 GRIN2B â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 34591642
NRAS BRAF â—¼   PROXIMITY ✅ 0.81 0.81 mint 30194290
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
DVL1 DVL2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
EPHA2 EFNA1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 7218654 19525919
MEF2A MEF2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25609649
CFTR DCTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
EFNB3 DLG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCTN4 DCTN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
ACTN2 ACTN4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
FPR2 GNB1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
BCL2L1 APAF1 â—¼   PHYSICAL_INTERACTION ✅ - 0.82 0.82 Signor 9539746
EFNB2 EFNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DLG1 ACTN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 12860415
CALCR GNB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ERBB4 NRG1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
SRC LNX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17936276
DERL1 CFTR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18555783 16901789 16954204 26618866
CFTR GNAI2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
ERBB4 DLG3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12175853 10725395
APAF1 BCL2L1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CALM1 SPTAN1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CALM1 CAMK2D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CALM1 GRIN1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CALM1 CAMK2A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
SRC LYN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 9169421 18070987 22581261
EFNB1 SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 8878483
ERBB4 ERBB3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7689552 10572067 20227043 25315821
FGFR3 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
NRG1 ERBB3 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 7514177
GHR GRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17474147 9632636
GRB2 DOCK4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31980649 21988832 21706016 33961781
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
DCTN1 DCTN5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26638075
DLG1 ERBB4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12175853 24550280
CACNA1A CALM1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALM1 CAMK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CAMK2D CAMK2G â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DCTN1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
NTRK2 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9648856 16713569
CACNG2 GRIA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ACTR1A ACTR1B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EFNA1 EPHA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14692877 7973638 8755474 19573808 20505120 8139691 22244754 19525919
ERBB3 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9756944 24189400 24658140 16729043 11173924
ERBB4 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16729043 22973453 24658140 25140053
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
DVL1 DVL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 28514442 20224554 33961781 26186194 31340145
DVL2 DVL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 31340145 33961781 28514442
LRP8 APOE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12950167 8626535 12167620 32814053
NTRK2 BDNF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21651720 11855816 9312147
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HIF1A BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15240700 12402042 15024076
ERBB4 GRB2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
AP2S1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12577067
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
TFAP2A CSH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10715552
CALM1 CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559563 12475216 20668654
CALM1 CAMK2G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10860555 20668654
APLP1 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ACTR1B CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FYN DLG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 13129934
ANXA7 DVL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TFAP2A CREBBP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
TFAP2A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12586840 12169688 17905638
PRKCA CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11463380 17570479 20577053
SRC EFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8878483 16189514 22279592
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
RGS9 PRKCA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11601986 11292825 12499365
PRKCA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 16810323 12917261
DCTN4 DCTN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26638075 33961781 27173435 28718761 34079125 26344197
AKT2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10869359
CAMK2A GABBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20643921
TFAP2A BACE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14701757 15059977
SP3 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19197985 19011236 19994725
ERBB3 NRG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31467278 30523157 10913256 9565587 7592681 8702572 28988771 11389077 17697999 33961781 11555649 9168115
ERBB4 NRG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10537356 9565587 28988771 8062828 7721889 9168115
NR1H4 ABCC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22291955 21296199
PRKCG GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936117 10862698
APLP1 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP3 CYP3A7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11495920
SP3 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19481140 22827437 14744778
EGR3 GABRA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20670676 16901909 16091474
ACTR1B DCTN5 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
DLG1 DLG3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 33961781 12351654 26496610
ERBB3 NRG1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
BCL2L1 BID â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
GNB3 GNGT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB3 GNG11 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
BRAF KRAS â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CACNA2D1 CACNB1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
C6 C8G â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8B â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
BRAF NRAS â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
DVL1 DVL3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
CACNA1C CALM1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ACTR1A DCTN5 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CAMK2A CAMK2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
EPHB2 SRC â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10644995 9632142 18713744
EPHB2 EFNB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 26186194 11780069
ACTR1B DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
DCTN1 DCTN4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
EFNB2 EPHB2 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ACTR1B DCTN4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ACTR1A DCTN4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EFNA1 EPHA2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DCTN4 DCTN5 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CSNK2B SSRP1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
GNAI2 GNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CAMK2A GRIN2B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GRIN1 GRIN2B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG11 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BCL2L1 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10811864 9488720 12963020 9539746
BID BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 9727492 19074440 16697956 15694340 17289999 25241761 22464442 14963330 16189514 27159560 24814347 15574335
HIF1A BID â—¼   DOWN_REGULATES ✅ - 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
CSNK1E BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11583622 12598529 20356928
CSNK2B BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11583622
DVL1 CSNK1E â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
DVL2 CSNK1E â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
CSNK1E DVL3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
CSNK1E DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 32888647 31515488 22609948 16189514 16713569 10517632
CSNK1E DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11425858 20006983 14966280 20215527 16965538 21285348 11487578 11818547
PRKCA EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 32413552 12040186 19568798 15567848 14585353
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
EFNA1 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8139691 20505120 23331499 11248553 14692877 24003208 7973638 8755474 18988627 15114347 9576626 22244754 9330863 19573808 11114742 19525919
FGF19 GRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 FLT4 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 FGF23 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 ANGPT1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 ANGPT1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 FLT4 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 FLT4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 ANGPT1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26552706 8551221
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FLT4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9927207 8662748 7675451 7970715
ERBB4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24658140 16829981 16729043 12731860 25140053
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
GNAI2 LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
KRAS CALM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 27410739 12727204 28666118 16043511
CALM1 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 3006921 17353931 20668654
CCK CCKBR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 10368033 12695525 10438490 8349705 15001692 15520004 7681836 23597562 15068617
FGF16 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16597617 25772309
DVL2 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
DVL1 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B DVL3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10837139 20976471 20558317 10671551 17374729 21285348 11972058 21506126 11689703 10747897 16707567
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
NTRK2 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 9648856
FYN GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 12451687 19477150 18673451 16713569 11024032 23162743 21686074 24611998 16190898 10458595 28497343 20722721 19874789 11483655 22009355 23127881 21896318 20053906 19482714 18932218 26229100 18691323
HRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
HRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
HRAS TIAM1 â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 7510700 7673236 8551221 9069260 9763606 9846483
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9069260 7673236 16203995 12134164 18568040
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
DVL1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 FRAT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
DVL1 FRAT1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
GNAO1 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19705439 19561403
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
CAMK4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11970865
TFAP2A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9328434 17224907 12391156 10523846 9632747 21377456 12903198
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
DVL2 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
PRKCG DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
PRKCA DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
DVL3 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
SRC FLT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16076871 12881528 20431062 18083107
GNAI2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
EPHB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18713744 10644995 9632142
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10884433 18184784 11483655 11024032
SRC ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12748290 12522270 19534553 20841568 18083107 17474147
SRC TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12810717 19285946
SRC CHRNA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16251431
SRC SPTAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12446661 11971983
SRC BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085087 16226010
PRKCA TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9407095 10212259 10734127
FGF17 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10751172 16597617 25772309
FGF23 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16597617 12032146 25772309
FGF18 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15781473 10751172 16597617 1578147310751170 25772309
FGF19 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16597617 25772309
ELK1 PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26010542 16297876
PRKCA ADRA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9353340 17570479
PRKCA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18755856 27571290
PRKCA GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12147342 11306676 8940188
PRKCA ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9824678 11779484 1827443
PRKCA GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15894802 9242710
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
PRKCA GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8316301 14973229 93302854 10049997 15936117 9030583
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
PRKCA EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCA GRIA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10366608 12536214
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
GNAI2 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNB1 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
TFAP2A APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17651731 9048735
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
APP FPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11316806 11160457
KRAS BRAF â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 24937142 16294014 12932339 7744815 9020159 15035987 16364920 11325826 16041367 24347342 12932319 10205168 21441910 23993095
KRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 23331499 19541618 8601312 14970219 18567582 16135787 12932319 17563371 12917261 19933846 21779497 17635919 19223544 15710605 8073291
NRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 21478863 9368069 19541618 8601312 14970219 18567582 16135787 7935411 12932319 12917261 17563371 19933846 21779497 8073291 15710605
EFNB2 EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 24003208 9267020 15114347 28719605 11114742 933086311780069 11780069 9330863
DVL3 FRAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12556519 23331499 10428961 9635432
APOE LRP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626535 12167620 12950167 16504486
CAMK2A GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12147342 11306676 19453375 21610080 16120608 8940188 11459059 22427672 16436603
CAMK2A GRIA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10366608 12536214
CAMK2A DLG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15044483 12933808
KRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
KRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
BDNF NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 76445409312147 7679912 21849472 27908981 9312147 23331499 9648856 11855816 26899129 7644540 1645620 26740873 9775403 21651720 28679669
NRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
NRG1 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10970856 16843264 7514177 7592681 23331499 8702572 7477375 11555649 9565587 16189514 26148232 9168115 9275162 10214951 17697999
NRG1 ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 9275162 7721889 25052836 10970856 10214951 8062828 9565587 14967450 10537356 9168115
NRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
GRIN2B GRIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12191494 19487695 15030493 8139656
CAMK2B GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12147342 11306676 16436603 8940188
SP3 AGTR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11779634 15507319
EFNB1 EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 24003208 8878483 15114347 9576626 11114742 93308638878483 9330863
FZD2 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
PRKCG GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCG GRIA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16713569 17570479 12471040 12536214
AKT2 SH3RF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14504284 17535800
ABL2 GPX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12893824 20841568
PRKCG GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12147342 11306676 8940188
GNA14 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309