Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HTT GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
GIT1 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
HTT GIT1 â—¼   COLOCALIZATION 2.0 0.8 intact 15383276 5217202
GIT1 HTT â—¼   COLOCALIZATION 2.0 0.8 intact 15383276 5217202
CALM2 CALM3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CALM1 CALM3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CALM3 CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9822657 10187789
CALM3 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
CALM1 CALM2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CALM2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
CALM2 CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9822657 10187789
HTT ACTR1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AK2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R5C ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20730097
CREB5 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8378084 8440710
ATF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18729081 20101207
CALM1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
CALM1 CAMKK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10770941 7642608
CAMK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAMK1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23707388
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R5C CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8386317 8195196
HTT GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GAPDH PHF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HDAC4 MEF2C â—¼   COLOCALIZATION 2.0 0.8 intact 5215014 11792813
PPP2CA HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18045992
HDAC5 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10737771 11062529
HTT KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3R3 IGF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0611271104 17360667
CALM3 CAMKK1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CALM2 CAMKK1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CREB5 ATF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 8440710
CALM3 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM2 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 NOS1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATF2 ATF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25609649 26344197 31964530
CALM1 CAMKK1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
IGF1R PIK3R3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCND1 XPO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21654808 12529437
ATF2 CREB5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CALM1 CAMK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ARHGEF7 RAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PSMD12 PSMD6 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CREB1 ATF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 20102225 1655749 8384217
CDKN1B CCND1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 34591612
HDAC4 MEF2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CALM3 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM2 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7685187 7493936 1722402
CALM1 CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559563 12475216 20668654
PPM1F CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9442023 10814834 15680915
CAMK1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17022975
CAMK1 PPME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24841198
CAMK1 GCM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21791615
CAMK1G EIF4G3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22514323
NAF1 DKC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19095616 26344197 26496610 16601202 26186194 19179534 28514442 16618814
BOLA2B GLRX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PPME1 PPP2CA â—¼   DEMETHYLATION ✅ - 0.91 0.91 Signor 18394995
CALM3 CAMK1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CALM2 CAMK1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ATF4 CCDC106 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ARHGEF7 GIT1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CDKN1B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5219242 17053782
PPP2R5C PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 6549523 1328865
CDK4 CDKN1B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CCND1 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PSMA5 PSMD6 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PSMD12 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD14 PSMD6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPME1 PPP2CA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA5 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMD14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD12 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R5C â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARHGEF7 GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10428811 21295525 12473661 10896954 16628223 16787945 10592173 12695502
ARHGEF7 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24792722 16983070 18684957 16492808 9659915 10592173 14557270 11309380
CAMK1 ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8384217 8621702 8663317 20068231 11018520 11335727 11909979 9016641 12414794
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
CALM1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
CALM1 CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9822657 11395482 10187789
CAMKK2 CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9822657 11395482 10187789 7641687 10400638 8253780 24835252 7642608 15262966 23110126 8631893
CAMKK1 CAMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9705275 10187789 15173201 7641687 8253780 17287469
CAMK1 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 15251453 27885874 10874031
CAMK1 DNM1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18838687 31063459 17553808 18695047
CAMK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8065343 15733869 7608156 1646483 9770464 9829964
CAMK1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15728188 11114197 11509672 15367659 11081517
CAMK1 SYN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 3118371 12237306 9395448 8022798 10571231
CAMKK1 CAMK1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12935886 18669648
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
CDKN1B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 9106657 10908655 17254966 25416956 7478582
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CDKN1B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 23602568 8978686 23707388 21439954 18850315 16326706 9658399 14597415 18615582 10198259 16782892 9632134 16189514 17053782 11360184 9311993 17092340 20837141 26186194 25241761 15695403 9464540 19470470 9106657 10908655 23543736 11940657 18285702
CREB1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17526027 19155497 19750005
HDAC4 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12709441 15743821 11279209 15964851 10523670 23752268 11792813 11504882 18332106 10737771
HDAC9 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20936779 15546868 20211142
IGF1R PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17496910 25241761 9415396 9524259
PPP2R5C PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18782753 15380617 1328865 28330616 16456541 11929880 10675325 19156129 8703017 7592815