Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSP90AB1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
SIRT1 HSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23349863 19229036
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
FYN STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
KCNA5 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO2 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1004248107 20534433
DYNC1I1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16616141 5218511
TP53 RAB4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KCNA4 DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215250 11937501
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
KCNA5 SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
DLG4 ACTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DCTN2 GOLM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KCNA5 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
ABCD4 SARAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
KCNA5 DOLK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 NPHP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CQ080 KCNA5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 DJC18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 GOLM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 ANKL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 ZNT6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 CA043 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 TM223 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 ABCBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 AT2A3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 GHDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 NB5R1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 SARAF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 AT2B4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 VANG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 RHBD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 5NT3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 ADCK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 S27A6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCNA5 TMX2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
DLG1 ACTN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 12860415
KCNA5 KCNA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11149959 12815189
KCAB2 KCNA5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 23390957
DOLK KCNA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
SUMO1 HSF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12646186 18211895 22748127 19684601 12665592 19597476
KCNA4 KCNA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10428758 10428084
DLG4 FYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12419528 16713569 9892651
SRC TNK2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
DLG4 KCNA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17854350 21726550 12435606 8938729
KCNA3 KCNA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 10428084 12944270
GNB2L1 PRKCB â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SUMO1 SUMO3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 15576338 17938407 21098080
GNB2L1 SRC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KCNA3 CAV1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26931497 34196606 18218624
DLG4 ACTN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12435606 21653829 16713569
KCNA5 DLG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12970345 16466689 24550280
DLG1 KCNA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7477295 9341123
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
KCNA4 DLG1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24550280 7477295 33961781 11997254 12860415 8938729
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
KCNA3 KCNA5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 18218624
DLG1 KCNA4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
TP53 SUMO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
KCNA5 DLG4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12435606 12860415 16466689
DLG4 KCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12438413 7477295 12435606 8938729
KCNA5 ACTN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11389904 10812072 16713569 12860415
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DLG4 KCNA4 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
DLG1 AT2B4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 12511555 11274188
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
KCAB2 KCNA2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 21357749 8636142 10428084 33961781
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
KCNA2 KCNAB2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DLG4 KCNA4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11744724 8601796 12435606 9581762 7477295 11937501 11997254 11723117 8938729
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HSF1 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21932106 24384723 15221402 20185824 20817212
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
HSF1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12646186 19684601 12665592
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
FYN DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12419528 25720756 18721130 9892651 16713569 22709448
FYN PRKCQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10383400 16713569
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PRKCB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCQ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC KCNA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11812778
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24981431 16990796 14529711 18721130
DYNC1I1 DCTN2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965