Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
STUB1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313385
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
INCA1 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
EGFR ATP5F1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MPP1 ATP5F1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAGOHB AMOTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AMOTL2 MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AMOTL2 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DLG4 MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SGSM2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
GYPC EPB41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22449961 8306834
FGFR3 MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
GSN FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6092370
FXR2 MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
G3BP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11137014 5213395
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MPP1 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MPP1 SGSM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MPP1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
MGMT MPP1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
AGR2 PRDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
STK3 PRDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
FXR2 G3BP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26777405 24778252 29395067
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TP53 WRN â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PRDX1 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18271526 31980649 23956138 20029029
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HTT OPTN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRDX1 PRDX2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
POLB MPP1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
ADIRF GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B MPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP3K20 MPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ADIRF RPS6KA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NAF1 DKC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19095616 26344197 26496610 16601202 26186194 19179534 28514442 16618814
GADD45A MPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPS6KA6 MPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPS6KA1 MPP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MPP1 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MPP1 STK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MPP1 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MPP1 NR1H2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 WRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9774636 11427532
MRPS15 MRPS26 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
RPS6KA1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11584304 11583116 23331499 8250835 7980435 8524413 24931005 19346560 12054501 16039586 12147701 11035810 22615844 16543730
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
EGFR EPB41 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 2171679 1647028
GADD45A WRN â—¼   REGULATES ✅ 7.0 1.0 ACSN 10779360 12124778 15917306 17599061 19004803 19652693 23485469
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
NCBP1 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
WRN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
TP53 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12080066 11399766 15735006 16713569 11427532
DCLRE1A MPP1 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
WRN MPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368