ABL1
|
PKD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
PTPRG
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PDGFRB
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731806
17620338
|
SHC1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
CBL
|
SRC
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5219404
17141222
|
CBL
|
MET
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215187
11894096
|
PTPRG
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
STAT3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731598
14966128
|
JAK2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
BMX
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
STAT1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10558875
22693070
|
PTPRG
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
SRC
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MYC
|
PDGFRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15226411
18697203
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
STAT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10637230
|
STAT3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22943793
15810077
|
JAK2
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
PDPK1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
STAT1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
ESR1
|
PRKCD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22430216
18414489
|
PTPRG
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PRKCD
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11266508
|
STAT3
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
PDGFRB
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17145802
17496910
|
STAT3
|
VIM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19088723
14712222
|
PDGFRB
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
9484840
|
PTPRG
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
ITGB2
|
ITGAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19161977
21270398
|
ITGB2
|
ITGAL
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19161977
21270398
|
VIM
|
PTPRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CTNNB1
|
VIM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22552774
12750294
|
BMX
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
PTPRG
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
SRC
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10964917
8755247
|
ZAP70
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15688026
5217506
|
SHC1
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6805769
9593725
|
PTPRG
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
EPOR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
8400282
|
PTPRG
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PDGFRB
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14973141
|
PDGFRB
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8657151
9484840
|
KDR
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15026417
9182576
|
PTPRG
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
ZAP70
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211965
10556826
|
WAS
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7208262
16107303
|
LCK
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
SRC
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16005629
15157149
|
ERBB2
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6730868
9461599
|
SRC
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15574420
14665621
|
PXN
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6169422
14665621
|
PTPRG
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
SRC
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
17158356
|
PTPRG
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
CTNNB1
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12640114
5216233
|
SRC
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731430
11940572
|
SRC
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6672010
16291744
|
PTPRG
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PDPK1
|
RHOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12783890
10753910
|
TEC
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
PTPRG
|
STAT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
MET
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10521801
16782899
|
PTPRA
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12700044
2809592
|
PTPRG
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTK2
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17893324
22952866
|
GRIN2B
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215250
11937501
|
RHOB
|
INSR
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
14722096
6672086
|
PTPRG
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
INSR
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12456798
|
CTNNB1
|
PTPRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8287660
21112398
|
ESR1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16628468
|
ERBB2
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ESR1
|
PTPRG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414489
|
PTPRG
|
BLNK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
DAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
STAT5A
|
EPOR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10882725
11013351
|
PTPRG
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
DOK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
CTCF
|
PTPRG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21150880
|
TIE1
|
TEK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
28396439
10995770
|
PTPRG
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
VCL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
EGFR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
KIT
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
8950973
16780420
25737303
15315962
|
CDH1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
NTRK1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25921289
21570973
|
RHOB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
DOK2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10508618
|
EGFR
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
25970784
|
SHC1
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
16729043
5218694
|
INSR
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
9121430
10482988
8702728
7559507
12237775
9446569
11075717
9710204
10803466
10896916
9741627
10921922
9593725
10816433
9083103
15629149
7499194
10764799
|
PCDGK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
MED21
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ISG20
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
NSF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
ERBB2
|
PTPRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32062451
28065597
|
MED21
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DUS22
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SDC1
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
PCDGK
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ISG20
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CXB7
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SPA12
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DUS4L
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SHC1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8112292
19380743
10194451
|
SHC1
|
EPOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16713569
8400282
|
INSR
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12456798
8912646
|
UIF
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
T185A
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCNL2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
FCN1
|
PTPRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
LEG8
|
PTPRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
LEG8
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
UIF
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
T185A
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
FCN1
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCNL2
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BTK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
ABL1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
SRC
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
6538879
18273061
|
SRC
|
CBL
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.84
|
0.84
|
mint
|
5219404
17141222
|
LCK
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
25814554
10825200
18070987
|
SRC
|
BMX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10688651
|
SHC1
|
ALK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11888936
33961781
16713569
9174053
|
CSK
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15144186
31980649
12485116
|
STAT1
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9344858
16189514
14978237
10358079
|
SRC
|
DOK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15831486
10428862
|
PDPK1
|
SDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
ESR1
|
NSF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
20348541
|
JAK2
|
STAT5A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
9575217
|
CBL
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26716506
12574167
25081058
|
STAT3
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
6730629
8662591
|
DOK2
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10799545
16189514
25814554
15831486
|
KIT
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8611693
7527392
9355737
|
SRC
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
17284441
6169640
|
DOK2
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15831486
12777393
9478921
|
KIT
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12374739
24728074
|
ABL1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22973453
16273093
19275932
|
MET
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6538879
18273061
|
CBL
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11149930
19380743
|
MET
|
CBL
|
â—¼ UBIQUITINATION
|
✅
|
|
0.86
|
0.86
|
mint
|
11894096
5215187
|
ESR1
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23874500
11429412
|
ESR1
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25303530
31527615
|
CBL
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
EGFR
|
STAT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
STAT3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
22693070
|
SHC1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
GAB1
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
24728074
|
JAK2
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11294897
15322115
11152457
12637327
7690989
20353823
19834108
14978237
15284024
10918587
24255956
7543024
12817007
7657660
11839738
|
TEC
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9473212
9178903
|
SRC
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24728074
12878163
12444928
|
ITGB1
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ITGAL
|
ITGB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
PRKCD
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
JAK2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24240702
9363897
10635327
16273093
23838182
10358079
|
ESR1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
28065597
20935677
11887937
17284441
|
BMX
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
16189514
25416956
10688651
25814554
21516116
|
SHC1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
KIT
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9788619
24728074
|
DLG4
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10839362
16713569
|
GAB1
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
PTPRA
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
STAT1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
LCK
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
SRC
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
BLNK
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
JAK2
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PDGFRB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CBL
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CBL
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
BMX
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
JAK2
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
NTRK1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10708759
10679771
|
EGFR
|
PTPRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32062451
31980649
28065597
|
JAK2
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10925297
11294897
15156153
30413785
15284024
11350938
12626508
12576423
11940572
10918587
12244095
8626374
9211920
19834108
26775640
14551213
27351213
23838182
|
SHC1
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10037694
19380743
12048194
|
SHC1
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
8235613
7961936
15688026
9685404
8761298
23267066
|
SHC1
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7731718
24728074
9660480
|
CSK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12387813
17525734
9208935
7678701
21746865
7513429
|
STAT2
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
24065129
|
KIT
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25241761
9355737
|
INSR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
KDR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EGFR
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
ERBB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
SRC
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11494128
17474147
12522270
11781820
17318191
|
ABL1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
16273093
25402006
7678409
|
ABL1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15556646
11494134
16713569
9174058
20675402
9195915
14604282
10829062
14725908
8626543
12475393
19380743
19823681
16955467
|
MYC
|
ABL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21400515
23029531
19602047
|
EGFR
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27059931
7657591
8665853
27903975
15107835
24797263
28791635
9756944
23799367
23175185
28198003
12734385
14505571
20940296
19155296
10635327
15117950
22833562
29629558
12061819
8662998
10086340
33762435
11994282
20877636
32714745
25005938
31182136
19578043
7782294
24714105
10799548
23158001
26055326
33617900
23153581
15210722
25872741
15657067
19947936
10428778
18508924
16969069
17971399
15962011
19531499
25521828
23774213
22976291
31959764
22591401
18255265
15735736
16713569
20562913
17880946
16914641
9890970
22394513
16729043
32114396
17995934
17182860
18319245
18271526
17545148
15383614
25140053
32377695
15465819
33627783
8798643
25754235
15282549
26177020
22266821
16923119
17242169
30544639
12604776
11239464
9130710
19225046
11370743
21772844
16105874
18273061
7592693
23897813
17486068
16246327
23457600
32904620
12803489
31120930
15668240
22203672
23418353
20124286
28541302
33323455
10092522
14627991
15677445
15159412
20308550
16849543
12593795
19836242
9121472
19713535
18316398
11408594
|
SRC
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29899407
17094785
16713569
18273061
7782294
12941616
10829062
31120930
15135048
17141222
18996392
8635998
11994282
22203672
19861161
16636290
|
BTK
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10826882
10427990
9408950
7629518
|
ZAP70
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16503409
9407100
22266821
8798643
10779765
11353765
9988730
10074432
10078535
29053960
11133830
|
CBL
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11894096
25241761
18273061
19433454
21222362
19450681
21163258
16397241
17533376
15123609
|
SRC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
17284441
6169640
|
ZAP70
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
22973453
24658140
16273093
25402006
|
EGFR
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20624308
24189400
21918175
24362532
10722725
23866081
26551075
|
EGFR
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
31980649
23956138
20145033
21573184
25402006
15485908
15657067
14966128
9756944
18258752
15284024
24189400
24240702
25754235
24135280
15950906
24658140
12873986
20067773
10358079
|
EGFR
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
23956138
11294897
15322115
24658140
12637327
7690989
15284024
10918587
25402006
7543024
12070153
12817007
10358079
7657660
11839738
|
EGFR
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
24658140
25402006
16729043
|
EGFR
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500850
25241761
30898150
17486068
11526509
9461599
23866081
17426253
10572067
11500516
24557338
8665853
15657067
19060928
16516204
19650109
20211985
25315821
23436906
21278786
25898135
32669362
1346931
24189400
21044682
18803307
16843263
28369073
7531698
16713569
17148612
21203579
17307140
1706616
16207817
7797556
12354693
11408594
|
EGFR
|
GAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23066441
31980649
10913131
9890893
24658140
10648629
21278788
25402006
10734310
18271526
19401591
11432805
|
STAT3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18367518
21590492
23504318
|
MAPK3
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15930121
|
STAT5A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17927978
12048235
12967477
|
MYC
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
INSR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
ISG20
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
PRKCD
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
25639486
|
PRKCD
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
27203386
|
ERBB2
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20876300
11940572
16273093
19372587
|
SRC
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
21573184
15313931
11294897
8657134
18070987
10918587
12244095
19372587
12626508
8626374
14551213
16713569
8272872
11350938
9566874
12576423
11940572
15735682
|
STAT3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21546410
|
STAT3
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20830236
|
ITGB2
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8649427
16189514
|
NTRK1
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25921289
7541035
28213521
9856458
10092678
10629055
29715200
8226808
8183561
10708759
8155326
12446789
|
SHC1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9710588
9019162
16713569
9756944
22973453
24658140
10085134
28065597
30898150
16843263
16273093
16729043
8665853
|
SHC1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20935677
11773443
16713569
|
ITGB1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19889638
10964917
|
TEK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14665640
|
SRC
|
KDR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15879121
20807769
11600407
|
KDR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24043698
22264731
29435030
|
SRC
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10592173
11723131
11259684
|
LCK
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
7961936
10556826
8798643
9685404
22242145
7539035
10318843
15144186
16461343
|
LCK
|
DOK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
10799545
16189514
|
PXN
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15719014
25241761
|
STAT2
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8621447
8605877
28514442
26966684
10446176
31836668
17923090
10490982
9724754
24065129
15825084
35140242
33961781
12048190
|
STAT1
|
JAK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12223098
21239533
|
STAT1
|
STAT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16918696
19122651
|
JAK2
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15644415
12506011
10455108
|
JAK2
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10925297
9553131
|
TEC
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11071635
7526158
24728074
|
SRC
|
ALK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14563642
19459784
18097461
|
SRC
|
PTPRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8647855
11923305
9261115
12468645
23532252
7518772
10698938
33961781
|
SRC
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24498420
14766010
15604093
11013076
27420286
29720121
12736255
18451880
15140878
23065768
17043237
17627277
7539106
11032808
17363140
20935677
14963108
11564893
12630920
22328528
15020686
15784253
17921256
24051437
10454579
17400812
17284441
16957778
|
SRC
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22973453
11940572
17875712
19372587
21075308
29720121
7542762
7797556
19704002
|
SRC
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24034250
20624308
9837958
24728074
|
ESR1
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20160136
20460377
22865929
|
LIMK1
|
RHOB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
RHOB
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9870943
9870942
16202622
|
PTPRG
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25624455
19167335
|
EPOR
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15644415
12506011
10455108
|
MET
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11439336
|
PTPRG
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25624455
19167335
|
PTK2
|
PXN
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
15688067
|
CSK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
ABL1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
CBL
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
KDR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CDH2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
PXN
|
VCL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
SHC1
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
7535773
9126968
|
CTNNB1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
36950384
|
ESR1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ERBB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
PTK2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CBL
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
PXN
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
25795725
|
PTK2
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
CBL
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
7721825
8621719
8900205
8626543
9178909
16107303
11741956
11904433
|
ERBB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5218411
16516204
|
MET
|
GAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10871282
10913131
10995442
10734310
9242692
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16729043
5218694
|
SHC1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10570290
10025673
16713569
8621719
9541596
8662998
9461587
9434624
9234717
8950973
19380743
15677445
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
GAB1
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9804835
24728074
12808090
14982882
|
JAK2
|
EPOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
14982882
12441334
11779507
8343951
|
JAK2
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
SHC1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7518560
8034616
31980649
23956138
9544989
8610109
7542744
25402006
16729043
8665853
15657067
9742218
24797263
10049786
12577067
9756944
23799367
25187647
20935677
10766863
18271526
11408594
7506413
10635327
10595738
24189400
19531499
7542991
20473329
24430869
8662998
9020193
8887653
16273093
25754235
9388490
31959764
26551075
16713569
22973453
24658140
11196191
28065597
20067773
8810340
21278788
30544639
9130710
11370743
|
SRC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
8845374
21573184
25402006
7506422
10075741
19704002
10971656
23175185
10777553
22227249
20935677
20624308
21268077
17158602
24189400
9020193
16713569
22973453
11983694
24658140
28065597
21278788
17284441
7797556
20333651
7527393
10358079
|
SRC
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10482988
16189514
7499252
9096689
9710204
18840094
8939605
9388490
26551075
|
PKD1
|
PKD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
30093605
21126580
21642537
10097141
9192675
19556541
11901144
20168298
|
BLNK
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21482705
12093870
10498607
16969585
10556826
21822214
|
NTRK1
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
EPOR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
SHC1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
PKD1
|
PKD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CBL
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
EGFR
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
STAT1
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16007122
11722592
16189514
25241761
28514442
26966684
8662591
11594781
31462771
35140242
33961781
25609649
12070153
|
DLG4
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ABL1
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
SRC
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
19901323
10964922
16497976
20841568
16787943
17570479
17318191
11847100
10500097
12522270
18691976
11494128
11781820
16076903
20168609
12748290
16464493
12445832
19369195
17474147
|
LCK
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16076903
16787943
17570479
11847100
|
NTRK1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
10708759
10679771
|
ABL1
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16705159
15923602
15793561
25821558
9111318
15143187
16705160
11593427
20841568
|
ABL1
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
12445832
15212693
12573241
8629002
17932028
10051622
25704810
8630736
34162728
9188445
16497976
20841568
27602755
11598012
9326643
|
ABL1
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7615549
15817476
11774284
16254239
15107421
12408869
15572663
11695992
15592455
16094384
10823820
20841568
16713569
9603926
7537852
|
ABL1
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18923184
17126298
9109492
16631755
19737086
28637715
20841568
10713049
|
ABL1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
9525940
11494134
16713569
20841568
10829062
17389395
16955467
12604776
9890970
10391678
9195915
14725908
7925293
11997497
12522270
15556646
9102067
11239464
11994282
9174058
12475393
20675402
19380743
14604282
8626543
15212693
19823681
|
ABL1
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
14993293
19275932
20841568
|
ABL1
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
9826708
12766170
9391119
9242692
10506185
8547236
10069803
7687741
10490849
11741535
21777671
8906793
12475979
9444958
7513258
7961992
15475459
9252406
7838524
7731718
8662889
7708691
|
ABL1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
24430869
15192046
33889303
16273093
16943190
14760089
29880877
15618223
33574089
8910327
12631709
25173817
25402006
20841568
33947961
34107301
34469737
19915609
32019812
2022651
34290403
33707748
15329413
7678409
9733788
8490966
28338646
3263271
15901825
2022652
10069801
7506413
24658140
8408058
34385595
31980649
1314835
7741752
18668345
28724430
12648464
25073158
26079946
34155348
|
ABL1
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8940193
17992189
20841568
|
ABL1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16099633
25164010
17618275
24465953
20841568
17318191
20840866
|
ABL1
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24836440
8940193
20841568
|
ABL1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8617726
1623525
10194451
19380743
10592173
20841568
8112292
|
ABL1
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20861316
17306540
20841568
|
ABL1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20841568
20101225
30692633
|
ABL1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8940193
16846476
20841568
|
KIT
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11994499
16780420
12444928
17904548
|
CBL
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11353765
15169881
18835194
20189481
|
SRC
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
9525940
7782294
16713569
18273061
10829062
10799548
10934191
12604776
9890970
17570479
9013636
15135048
17094785
25784557
8635998
10092522
12522270
8621719
17141222
16636290
11239464
19861161
11994282
12941616
14739300
22203672
8849724
15212693
|
INSR
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
11997497
10635327
11994282
12522270
9525940
12604776
10592173
17570479
9102067
15951569
10829062
15212693
11239464
|
LCK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
9525940
10829062
10799548
10934191
7721825
16107303
12604776
9890970
17570479
11904433
9178909
10092522
11997497
12522270
8621719
9102067
11239464
11994282
11741956
|
CBL
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9092574
17904548
25737303
8950973
15315962
17635922
10514377
|
CBL
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
11133830
10779765
10358158
16503409
8798643
20189481
22266821
23109003
18835194
10074432
10078535
15268851
15169881
26192618
9407100
9988730
11353765
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16397241
15123609
23331499
25241761
21222362
11894096
18672314
21163258
19450681
18273061
35309168
17533376
19433454
17635922
10514377
|
CBL
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9234717
10347229
18988627
17635922
10514377
|
CBL
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
25102001
20332299
17635922
10514377
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10428798
22431515
23390529
17570479
23770852
|
EGFR
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
SRC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
16414009
17081983
25958313
16943190
15618223
19935697
19305428
25402006
24797263
29285309
7488034
15592458
17389395
16461772
20562096
19275932
17897439
15899872
17570479
2803273
23636329
23246962
25505586
23175185
15615697
23349873
16849545
25356505
11983694
24189400
11756413
25748412
26325669
26150526
14512423
18789131
14750954
31978707
25573954
27495374
20071362
18707149
28759036
16729043
26494466
27716204
25537504
17237269
18687633
25884760
29036202
26936397
17575160
20926745
20935677
15282306
23702846
15476828
9069259
19336574
20421302
15660394
23866081
19377510
9777370
22426783
29321659
33706413
25841779
19840943
18669648
12397069
16843263
18957516
34088769
25077442
14963038
19836242
17653080
19625610
16936701
11960379
15548697
18295415
17523611
21268077
20333651
21399647
23376850
11250711
23942551
19704002
22927910
11160627
31952541
10777553
17016520
2543678
19258037
33883672
17646646
28102297
23873690
26771606
21573184
23119029
19151764
16713569
7797556
25955608
15302935
20407013
28513565
23119185
9990038
21080693
20190765
25347738
14630916
15708852
21822308
20628053
25301722
24658140
19690143
27564112
20802523
29124875
33657368
12101233
21787862
14764607
17284441
12878163
26290602
15951569
16543144
15212693
17971399
14523024
10971656
21278788
8845374
22430206
18083107
29641465
18234969
18460189
17551925
22957061
26571308
17043637
20371672
10358079
16799092
19154417
23066441
28065597
12842895
18180459
17158602
18271526
15657067
25159151
34367939
24919575
10075741
25366117
24349301
17561374
16862179
20215522
31980649
24335899
16037379
18451158
14530278
16505275
12063263
23449029
11311660
|
CDH1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17548604
10969083
15662113
31980649
14681060
25241761
24189400
25468996
24658140
25402006
|
MAPK3
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
1651322
17081983
3138233
15901825
16785992
1939237
91332050
27531070
17570479
2543683
2115882
34086370
17192257
1651323
15302935
|
PRKCD
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
11447289
8321321
11313945
12040186
15302935
6321473
1860884
6090944
19568798
14585353
17496910
21386996
2984676
11940581
85012702
19615955
2987962
12845332
3379075
15567848
16488589
17956904
|
JAK2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17389395
10635327
17081983
10358079
16273093
16799092
18691976
10459005
9363897
15284024
23838182
17016520
18669648
15302935
|
EGFR
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
19901323
15231819
16497976
25402006
17389395
20068231
23066441
11432805
9658397
19509291
18669648
10978177
10753869
10734310
11896055
18271526
24658140
10648629
11779868
31980649
15212693
9890893
17016520
|
EGFR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19104148
27401557
15371335
16099633
22558232
30747223
12040186
26509276
24816560
12740122
25500543
17318191
19568798
21423209
14585353
34227224
23640056
17496910
17052462
24240237
25164010
14517306
21903109
22200182
16952352
20858269
28035485
9233779
|
EGFR
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
23331499
31980649
10358079
24658140
25402006
18586824
16729043
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
EGFR
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
17081983
16207817
21044682
17148612
24557338
16713569
21203579
10233167
20471394
17389395
17486068
21278786
11500516
11279155
11500850
17426253
16843263
19650109
25241761
24189400
15657067
17307140
18803307
1706616
12354693
10572067
24355130
11408594
19060928
12648464
16516204
15951569
23436906
20211985
|
EGFR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
78.0
|
1.0
|
Omnipath
|
9544989
8808684
10595738
23956138
9388490
11350724
16273093
7542991
7681824
7518560
9710588
23799367
16713569
25402006
11370743
24797263
9742218
20935677
8887653
8034616
23331499
8662998
7542744
10049786
28065597
9130710
10635327
24189400
7506413
18271526
15657067
24658140
8810340
12577067
11196191
10766863
23178716
31980649
35384245
11408594
19531499
9756944
26551075
1623525
15951569
16729043
17956904
|
EGFR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16713569
16919435
25402006
10806474
29435030
20473329
7657702
19339212
17496910
15657067
24658140
19625610
7529872
20802513
31980649
10545505
24043698
15951569
|
EGFR
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
23956138
12070153
11839738
10918587
11447289
11997436
14967450
25402006
12040186
24797263
15173823
7543024
15322115
10358079
6321473
11294897
7690989
10982844
19568798
12637327
14585353
15199124
17496910
11438544
10748192
24658140
7657660
12817007
31980649
22693070
9355737
19615955
11152457
15284024
15567848
7592750
16488589
|
EGFR
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23956138
12070153
20145033
14967450
20032199
21573184
25402006
10358079
23894143
14966128
24135280
25241761
14963038
24189400
15657067
24658140
15485908
15950906
18258752
31980649
9756944
22693070
12873986
15951569
15284024
|
MAPK3
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9804779
20508164
23331499
24263804
18775330
10194762
12407017
8226933
17502367
34188118
9604935
18988627
31932645
8388392
12091337
|
MAPK3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18463697
9155018
21071413
32482868
18988627
15210690
|
MAPK3
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
18448488
19413330
11335711
9343414
23331499
15465816
25584415
12576423
11350938
20068231
12681450
10417333
12763138
9872331
18988627
11780390
18491316
18669648
11404481
10521505
18691976
19723038
20058876
14551213
10446219
|
MAPK3
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
8506364
8618896
8226850
7597029
|
MAPK3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10949034
18372406
15461668
9528769
12118371
14680484
17615152
15059947
16076840
7491495
12093745
15212693
15528270
7838153
|
MAPK3
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12008033
15379552
|
MAPK3
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10537323
17081983
18088087
15144186
21079800
16964243
20444238
|
STAT3
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
CTCF
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10625678
8649389
2284094
12032779
19568426
24725430
12524457
8246978
12897849
9591631
1795697
|
STAT3
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19289167
17204573
18184402
22317895
20067773
15184887
15469392
10464281
9325164
20654581
21573184
17959148
22349830
9874564
20581311
19259613
|
CTNNB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21533051
19778454
16510874
12095419
17360646
18852287
15576399
19561604
20300972
19662654
15579438
17724465
9727977
24447505
18679417
12907606
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9632747
19176757
23364919
10523846
|
MYC
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20920219
21627565
7906953
23421821
20716114
|
MYC
|
ITGB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11381265
16878156
12695333
|
CTNNB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
16574648
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
LCK
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17389395
18691976
15541367
10319993
19144319
16497976
15133032
17016520
11381116
15302935
|
PDPK1
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
16505477
21310943
11839738
31511386
9748166
25472878
25755284
15811957
15133032
11781095
19664995
15024053
15302935
15949469
14581488
28784722
17570831
18669648
11381116
20058876
17965192
19632318
20501830
|
SRC
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15851033
14970215
17569658
19366211
26876198
27203386
15961393
24211614
16982614
17570831
23329791
23329794
15541367
18550549
22689788
28637715
14715667
29422059
17658731
10319993
19138410
11927579
29452094
19632318
15337529
|
PRKCD
|
PTPRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19651622
17081983
23532252
11923305
18809727
12826681
11676480
15212693
|
PRKCD
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12024011
16963224
17956904
|
PRKCD
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
76.0
|
1.0
|
Omnipath
|
8272872
19413330
11335711
15677447
9343414
15465816
8140422
12576423
11350938
7678052
20068231
12754507
9880505
12763138
9872331
18491316
18669648
8662591
10521505
18691976
27036017
27458446
7537214
8626374
20058876
25280942
16951338
14551213
8164674
12754506
10446219
12361954
12754505
16418226
|
PRKCD
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23823319
16301335
29903913
11700305
17107954
18550856
25278023
12682249
15212693
|
PRKCD
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
7925482
15075332
11447289
19615955
8294430
16488589
6321473
8321321
12845332
11313945
94124523
12040186
19568798
15567848
14585353
|
PRKCD
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
95354205
11839738
17502367
7543024
15322115
18035482
20068231
18452278
7690989
14550502
12637327
18669648
18691976
12817007
11972023
20058876
9355737
12807916
14963018
|
KIT
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23073628
15790786
11369651
15007386
12481435
15526160
28403213
10358045
28192400
17546049
9355737
|
STAT3
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23073628
15790786
11369651
15007386
12481435
15526160
28403213
10358045
28192400
17546049
9355737
|
JAK2
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
11867689
14610620
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
STAT1
|
STAT3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
46.0
|
1.0
|
ACSN
|
10485906
10754326
10820262
10952726
11134049
11399519
11830590
11875494
11964313
12193701
12223527
12433365
12796776
12811837
12907458
12967644
14607900
14607933
14660645
14764699
15465827
15644117
15699106
15814715
16127449
16878026
17016554
17260466
17404308
17485448
17513775
17559085
17689680
18272812
18345002
19833085
19879327
21097505
21263073
21930765
23390297
25960930
6357187
7594497
8683106
8871614
|
STAT1
|
STAT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19122651
17558387
22693070
|
SRC
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
19901323
10918587
9305919
8272872
29036202
9344858
12626508
10815799
16497976
15592455
16713569
17389395
12576423
11350938
9484840
11294897
28978186
18070987
12244095
27472461
21690253
23928694
22303479
8657134
11404481
9083098
14963038
8626374
17016520
9566874
10982829
15212693
11940572
11429593
14551213
15037656
15313931
11850821
9154828
9582023
|
ALK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
17145710
10918587
9305919
8272872
12626508
16084951
15592455
23331499
12576423
11350938
11294897
14968112
12244095
9083098
8626374
9566874
11940572
11429593
14551213
11850821
15212693
9582023
|
LCK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11404481
9484840
9344858
18070987
10815799
16189514
10825200
25814554
|
JAK2
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
167.0
|
1.0
|
Omnipath
|
10918587
8272872
16319070
18718905
15592455
34066153
23166634
33986510
17389395
29162862
29449694
33512408
21098725
9083098
17565041
27748760
27344175
34031055
29290793
21285325
33846242
33774038
9566874
25962054
20826784
14551213
26188635
26008966
15284024
26175413
21481791
33774344
26307676
9305919
10925297
15615703
12626508
16497976
32087696
16469875
31914141
23331499
11350938
28978186
16306356
33824475
18988627
17401459
19147545
15151905
12637586
34433042
8626374
15950906
27181202
24793791
20455003
21575192
32094172
15322111
17016520
34247191
19901323
12626585
27086926
21166956
23906537
31976162
9211920
12576423
22306293
10207096
12075083
11294897
26787900
12244095
14701810
33909625
11803465
17360477
28827891
33820781
19159681
18939995
11445068
27941883
11429593
30054295
26675255
11850821
9582023
34067421
34707127
15786731
25986861
27351213
34118143
15077188
26699492
12595539
21071413
18498667
22153071
15156153
33513694
25915428
11940572
12529382
18525315
24501689
33839684
24316223
19834108
9575217
|
STAT3
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
25609649
8662591
12070153
31462771
25241761
11722592
8710878
9794795
23268184
15284024
16189514
9535918
11594781
|
SRC
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
27601470
17570479
16189514
10688651
|
BTK
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12573241
|
TEC
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12573241
|
BMX
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
27994061
18437915
21454698
21289086
16291744
22940691
12639965
17117420
23716717
28053086
16920701
16415178
20473329
20658524
21918175
15735019
23466867
17692050
16189514
15707572
20501847
12482769
11909938
16153436
20802517
14656986
15371459
11331870
14645233
16782899
15026417
15561106
14761895
17215324
19815712
25617365
11839772
27226554
29311227
17449913
12871985
17088251
17317726
22490227
12876384
18250445
18664639
32839549
21059620
|
SHC1
|
ALK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15226403
18097461
16878150
17274988
16317043
11121404
|
SHC1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
SHC1
|
KDR
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
ZAP70
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
19901323
7961936
9388490
20230923
9096689
16497976
9121430
15592455
9446569
10891441
17389395
11687594
18578522
10921922
10482988
10764799
18452278
20068231
16189514
18669648
12522270
9685404
10896916
9927207
15688026
12237775
8702728
8610109
19651622
9741627
8761298
9710204
19664994
17016520
10816433
11075717
|
ERBB2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
28065597
23331499
9756944
16273093
8026468
9710588
10085134
24658140
9590694
16713569
16729043
16843263
|
PDGFRA
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
15592455
9121430
9446569
12767520
10921922
10482988
10764799
17673906
17496910
12522270
9685404
10896916
9927207
8702728
12237775
8610109
9741627
9710204
10816433
11075717
|
PTK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11980671
10592173
16713569
10725339
10749687
9566877
|
KDR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
10749680
9405464
11950700
|
LCK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
19901323
20230923
16497976
9121430
15592455
9446569
17389395
18578522
10921922
10482988
10764799
18452278
20068231
18669648
12522270
9685404
10896916
9927207
12237775
8702728
8610109
19651622
9741627
9710204
19664994
17016520
10816433
11075717
|
ALK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
12185581
16713569
9174053
|
NTRK1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
8155326
9715270
8226808
15056278
10708759
8552402
9856458
23331499
10629055
10092678
12446789
8524391
25921289
7541035
8183561
|
MET
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9083103
11687594
9660480
14990987
24728074
8084588
8939605
8947042
7731718
11884620
15688026
14685170
|
JAK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9126968
7535773
|
PDGFRB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
15592455
9121430
16713569
9446569
12767520
23331499
21071413
10921922
10482988
10764799
8195171
17673906
17496910
12522270
9685404
10896916
9927207
8702728
12237775
8610109
9741627
9710204
10816433
11075717
|
SRC
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
19901323
9388490
8939605
9096689
10971656
16497976
15592455
9121430
10891441
17389395
11687594
10329689
10482988
20068231
17570479
16189514
9685404
23109003
7516469
9927207
18840094
15688026
15212693
1409579
14963047
9710204
26551075
17016520
11075717
|
INSR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
93.0
|
1.0
|
Omnipath
|
9083103
17145710
19901323
10803466
20230923
16497976
9121430
15592455
9446569
17389395
18578522
7559507
7537849
10482988
10764799
10921922
18452278
20068231
10592173
7499194
18669648
15629149
12522270
9685404
10896916
9927207
9593725
12237775
8702728
8610109
19651622
15212693
9741627
9710204
19664994
7685165
8626723
17016520
10816433
11075717
|
CSK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12767520
12048194
18829532
9819392
19380743
10037694
17673906
|
SHC1
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11707404
14982882
24728074
10871282
10194437
9804835
12808090
|
PDGFRB
|
PDGFRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFRB
|
PDGFRA
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFRB
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17496910
8549654
11447289
19615955
9484840
16488589
6321473
11997436
12040186
19568798
15567848
15173823
14585353
15199124
|
PDGFRB
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
21071413
2161888
2542288
7523122
1847074
16189514
11331882
10417313
|
PDGFRB
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15489898
18315570
16189514
9010229
2173144
|
PDGFRB
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
9484840
25241761
|
PDGFRB
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10806474
20802513
16713569
|
ESR1
|
KDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16574784
18006642
|
SRC
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19050761
18662404
18194650
10749680
12509223
18377662
10455194
16966330
12214271
|
ITGB1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8649427
21909923
8878413
10545505
7657702
9003039
19339212
19487819
19161977
16189514
16919435
7529872
19889638
|
LCK
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CSK
|
LCK
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
CSK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
56.0
|
1.0
|
Omnipath
|
20346773
19901323
10692391
11489946
22566970
24463463
2141684
16497976
15592455
20813252
10799545
14967142
27547268
24764511
28522807
16537894
12485116
8193535
24227778
17897955
8183556
22426112
89123626
15489916
14610046
23109003
18691976
28448599
17947241
1639064
12414720
15144186
27460989
24816556
22507872
8631775
15743820
25979654
8945479
11181701
27045023
25595912
15259016
|
LCK
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9500442
10571988
25386784
11145737
7539106
27748765
|
LCK
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
110.0
|
1.0
|
Omnipath
|
23874979
7961936
17579062
29073235
30992398
15292262
23933134
31932281
21829558
15592455
21917715
9199177
8798643
7612267
16339550
23331499
10202147
22238573
16189514
32184287
21103055
7642520
33531381
12648457
12522270
17998387
9685404
20945976
16839418
15144186
16461343
16094384
11270871
17192257
10037717
8756661
19606965
23758320
27869819
16111633
25137454
15268851
17942891
33482200
11514606
11514605
15659558
10556826
10318843
|
LCK
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
25885255
34021045
12060651
9813040
12456798
21716071
12970160
10825200
11641791
9573010
31697835
11046040
18250158
22177802
22442148
29228564
11254359
19923221
12879454
14522994
20667852
|
LCK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11369622
12590707
15728464
9257837
10753828
|
LCK
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17570479
9788619
24728074
|
LCK
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
11839738
10918587
11438544
11152457
9355737
10748192
11294897
7657660
7690989
12817007
12637327
10982844
7592750
7543024
15322115
|
CSK
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
55.0
|
1.0
|
Omnipath
|
11489946
23051580
20657842
20337577
7592628
23824743
21940449
26453921
22323292
14665621
17525734
14967142
3103926
23159740
16227616
1383688
12387813
20525307
10698938
7525268
19534553
16537894
26234813
10592173
12468645
7513429
24632723
7687537
21442427
22689825
25372749
11007774
9208935
18614016
28974561
21632985
19369195
17855352
7678701
23378895
9523754
|
CSK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18823558
21829547
9890993
27803182
21062671
7529872
21709741
|
CSK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17389395
18707149
27447856
11695992
7529872
9890993
14665621
|
ZAP70
|
PXN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
PTK2
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
16298995
26053221
15688067
15572663
15592455
7963537
17389395
25405379
26546726
9658172
15107421
22581436
10823820
16254239
25226367
15817476
10330411
9756887
19543320
9054445
10545505
18707149
29127427
15494312
10764815
7537852
9442086
33823745
12408869
20419088
20655620
22270917
18669648
28373581
10455189
16094384
23936270
19138410
22638989
11337490
11514617
27402964
16713569
7615549
10931187
11774284
26700725
27708220
20068231
20473365
28928239
7561682
34475475
28427224
28068967
8922390
24885567
23209645
27669437
15212693
26711338
9422762
11304546
28214467
26697169
12065577
28415719
10753828
11919182
24364863
9230116
11113628
21741599
10417825
15252114
24642576
22044652
21034468
|
SRC
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
9636140
28214467
15572663
15592455
16713569
14665621
25795725
7537852
7615549
25405379
11774284
26700725
25182764
15107421
7534286
2472406
12408869
11695992
17570479
10823820
7525621
20103658
16254239
15817476
23109003
27447856
28626446
16094384
18363833
19543320
24364863
28376152
19138410
25323586
27941878
23457577
10085298
22638989
27669437
15212693
|
STAT1
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
STAT1
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23073628
15790786
11369651
15007386
12481435
15526160
28403213
10358045
28192400
17546049
9355737
|
STAT1
|
STAT2
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
JAK2
|
STAT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
PDGFRA
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
11447289
19615955
9484840
16488589
6321473
11997436
12040186
19568798
15567848
15173823
14585353
15199124
|
JAK2
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
11839738
10918587
7888666
20353823
7543024
15322115
25950470
23331499
21071413
14978237
11294897
7690989
7504785
18988627
12637327
25535282
11438544
21576360
10748192
7657660
12817007
14984365
7504784
21207025
9355737
11152457
7615558
19834108
15284024
10982844
7592750
19787091
|
KIT
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
11839738
10918587
11447289
11997436
12040186
21135090
15173823
7543024
15322115
6321473
11294897
10358045
7690989
15567848
19568798
12637327
14585353
15199124
17496910
11438544
25241761
10748192
7657660
12817007
9355737
19615955
11152457
10982844
7592750
16488589
|
STAT2
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10490982
8621447
24065129
17923090
15978943
1502203
10446176
9724754
14722125
21178011
15825084
21268015
12048190
8605877
|
PTK2
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20576130
25241761
11278462
16189514
|
SRC
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
11839738
10918587
9344858
7543024
15322115
10358079
14978237
11294897
7690989
16189514
12637327
11438544
10748192
7657660
12817007
9355737
11152457
10982844
7592750
|
SRC
|
JAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11476890
12094222
16919435
17496910
17517963
25572304
26552706
27216177
|
STAT5A
|
JAK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10882725
7744007
21719533
19036881
9343435
9698919
11713228
19638583
16847321
|
KIT
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8611693
7527392
15526160
9355737
|
JAK2
|
TEC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9473212
9178903
|
JAK2
|
EPOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
10660611
12441334
7559499
8343951
18672044
11779507
12027890
11443118
12524467
9030561
9573010
15212693
10579919
|
JAK2
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
17081983
34197875
7925280
16497976
15795318
18083107
17389395
23331499
15504549
19534553
9047382
21071413
11641791
18988627
8617237
18250158
19088846
15256422
12529425
28676702
11413148
17016520
9575217
|
KIT
|
STAT5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23073628
15790786
11369651
15007386
12481435
15526160
28403213
10358045
28192400
17546049
9355737
|
SRC
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12878163
7520444
10523831
|
KIT
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10358045
|
KIT
|
TEC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7526158
24728074
10397721
11825908
|
CDH1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CDH1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
CDH1
|
CDH2
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
ESR1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12726856
14500345
17893710
19383788
19593637
20101232
|
MET
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17496910
17336101
22558232
16909210
12040186
19568798
14585353
|
CDH1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
19029934
22370635
16099633
23343194
19734908
10744074
16039586
22203675
19171760
22007144
19619488
17143292
|
CDH1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
91.0
|
1.0
|
Omnipath
|
17145710
7542250
11348595
9512503
10652321
19016843
16909210
9233779
17220478
16219695
27177845
25344754
11245482
22752307
16983094
16212417
16574648
18593713
9535896
9819408
12830000
10772923
11801604
23180380
8227214
16546130
10085258
22056988
9700170
12640114
24424122
10381631
17087658
24798214
11226248
12875984
9405455
11712088
12061792
17909039
22158051
11960376
14706341
11254878
15023525
12169098
21255999
16125672
22850631
16126725
11113628
25468996
9326449
17524503
17057644
7876318
11401320
22715382
7954478
18593907
21152425
22375065
|
SRC
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16371504
15782139
9592087
16492141
9278444
28163245
10502299
|
CDH2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
18948590
20398329
21506126
20028971
12040186
12604612
21303971
20214616
17098867
11882383
22094462
8120095
21357690
17679699
17680028
12151522
17057644
21255999
18218901
|
SRC
|
PDGFRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7685273
9488729
10508235
9739761
|
SRC
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11476890
12531888
16919435
17496910
17517963
20027185
25572304
26552706
27216177
8892616
|
ERBB2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16769082
19617202
11940572
12753909
21075308
7542762
|
PDGFRA
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9988270
17081983
14661060
6273838
15489898
11278940
15845350
12753909
11804588
7578094
|
SRC
|
PKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11113628
11274246
12637538
21126580
10362514
|
SRC
|
VCL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
28592633
25115937
15229287
28684609
|
SRC
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
20643654
14585963
16314505
11481331
15212693
12738763
1148133
15302935
|
SRC
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10884433
18184784
11483655
11024032
|
SRC
|
DAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15062102
10959835
17570479
15316068
11279201
|
SRC
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
216.0
|
1.0
|
Omnipath
|
27351421
23242524
16254240
12370821
21940449
26142360
17525734
10593973
14604860
17389395
19171305
22402981
19339212
22353809
9748249
8941336
17570479
12464388
25226367
15611085
15817476
25241761
26393679
27978555
26833789
11927607
17828307
25913180
26866924
15247219
10085298
12387730
19055942
9507031
21454698
10973994
32814053
21057587
27931517
27438371
18793427
19695571
15735019
18560762
10592173
25319025
24389213
21852560
26689988
14984767
7505391
19568240
20103658
20822514
25868388
23275294
28423510
23764511
19625610
15561106
17192257
19138410
19369195
17088251
12753909
28701735
29190494
17016520
15598735
18814847
11821402
11418135
15728464
16291744
25067788
11602246
16713569
22287273
9032297
7997267
12960434
11369622
20616959
26079101
19534553
10931187
22710722
20068231
25866790
21347260
9822703
28202937
16153436
11980671
21855630
19826415
18464795
7529876
20621036
9330873
21473875
9425168
28956212
12615911
15951569
25814554
12876384
17438336
15212693
16966330
20705914
20847951
23729178
20407018
12558988
25127991
25918719
12590707
16360410
8054685
18814027
11696015
22800863
17117420
12495636
11278488
9864370
21776383
18083107
22814579
22194915
20515733
11119718
9148935
10428489
15743500
20655298
23065768
28213315
26923073
24015220
17289681
12110680
22006118
24164353
23109003
18935208
10753828
18233957
8816475
25118939
19664994
25530216
16760434
9330875
21266176
21034468
|
SRC
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
26706435
15574420
19881549
12941962
21442024
12808090
|
SRC
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
24728074
24034250
9837958
17570479
|
SRC
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11413148
17081983
10358079
22090359
7925280
16189514
15702476
11641791
15212693
8617237
|
SRC
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
70.0
|
1.0
|
Omnipath
|
27603901
22823952
7680654
9748248
28522963
19419567
19690332
16497976
15592455
19413330
25077552
17389395
19534553
20068231
28769876
17570479
20708589
19273217
18491316
18669648
16162656
25682866
12522270
18088087
22761768
26142315
17287340
27009365
10921917
9683637
24465712
27758765
24675741
12601080
18707149
16212419
15169891
7519605
17016520
11389697
|
SRC
|
PTPRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17389395
10698938
18578522
16507567
8670803
20158519
20068231
10623581
8647855
7518772
7691597
11923305
16497976
9535845
9261115
12468645
16505154
17016520
|
SRC
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24981431
16990796
14529711
18721130
|
SRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
22605996
16492141
27177845
23824743
25423132
25850673
24816560
27203386
11836526
22515442
26918136
10593980
15782139
9592087
22056988
12571228
17087658
20840866
23640056
21195420
25164010
26453937
9278444
16831887
23476652
12123611
11279024
14517306
21903109
22200182
20026641
22264731
25041845
12408824
22247700
|
SRC
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
15784253
25364741
17400812
16957778
17627277
15140878
11032808
23065768
12736255
7539106
17921256
27472465
14963108
24487689
25275301
12630920
22865929
14766010
30148069
11013076
15020686
9500442
17284441
|
SRC
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19109164
23170196
8629002
29455639
10051622
8630736
26165234
9052864
|
TEC
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12445832
12573241
8629002
8630736
16497976
11598012
|
MET
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
15611085
29435030
30134553
22188814
24043698
16782899
14572662
15247219
15561106
20802513
15598735
|
INSR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9507031
17389395
19664994
20068231
17570479
17016520
7529876
16153436
|
ERBB2
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17496910
19617202
25241761
10545505
7657702
27638858
19339212
27939360
15743500
20201928
12753909
16919435
16713569
7529872
12600989
11807823
|
PDGFRA
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24043698
20802513
29435030
|
DLG4
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20018661
16990796
11997254
9278515
7569905
33000527
11937501
10488080
9581762
11723117
12738960
8601796
|
PTPRA
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10940390
8244979
11850117
10852715
1321126
1599438
|
INSR
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
10753869
10978177
17389395
19881549
10734310
20068231
9890893
9658397
16497976
26929352
17016520
18669648
11323411
|
ERBB2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17496910
7702605
7999105
22558232
14517306
11245482
11950845
12040186
19568798
23576562
14585353
23640056
|
PKD1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11274246
26764245
11113628
22511927
|
MET
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
17496910
25163657
24511551
22558232
11929826
16909210
24342833
12040186
26654598
19568798
14585353
23083465
|
ESR1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
24559156
16115928
16467118
17992604
19915977
15199112
21127199
21761336
21907803
20551150
11713584
1358436
20629094
18768663
19005469
9242384
20889718
10698518
16467117
|
ERBB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
15173068
|
STAT5A
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11731618
22201800
11682624
11682625
|
MET
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
10978177
17389395
19901323
10753869
15574420
15212693
10913131
10734310
11896055
20068231
10995442
9890893
16497976
14685170
17016520
18669648
11779868
|
BTK
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
11413148
17389395
17081983
7925280
16497976
11641791
17016520
8617237
|
EPOR
|
STAT5A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8977232
15644415
10374881
27752093
|
TEK
|
DOK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11689432
23331499
9764820
|