YWHAZ
|
CAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
MAPK1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
PAK2
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20936779
|
MAPK14
|
CDKN1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22820251
22569127
|
CFL2
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
YWHAZ
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215799
12361576
|
LIMK1
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20133759
0914492107
|
HUNK
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20133759
0914492107
|
CFL1
|
LIMK1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6173882
17853892
|
SSH1
|
CFL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12684437
|
YWHAZ
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AA1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17188549
16641196
|
YWHAZ
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AB1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17188549
16641196
|
HSPA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
LIMK1
|
HUNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20133759
0914492107
|
MFHAS1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
YWHAZ
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215799
12361576
|
PAK3
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
LIMK1
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
LIMK1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
LIMK1
|
MAPKAPK2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456544
5218304
|
LIMK1
|
MAPK14
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456544
5218304
|
PTPRG
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
MFHAS1
|
TADA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
PAK3
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK3
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
YWHAZ
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
YWHAZ
|
SSH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19371722
8008908
|
MAPK14
|
MAPKAPK2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
14499342
|
POLR2B
|
RPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
KIF23
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
SSH1
|
COF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25100728
12684437
16713569
21525957
11832213
32015554
|
CV015
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
32296183
|
RHOB
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
RHOB
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
RHOB
|
PI4KA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
RHOB
|
PTPRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
ROCK2
|
ROCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MAPK14
|
MAPKAPK2
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
RHOC
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
31871319
31980649
|
BRAF
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
PAK6
|
1433Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
32707033
|
RHOB
|
ROCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34079125
31871319
34187934
|
ROCK1
|
LIMK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10436159
11018042
23082153
11340065
|
LIMK2
|
COF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10613909
10436159
11418599
9655398
23082153
11340065
|
LIMK2
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9089416
8980133
33961781
|
ARRB2
|
COF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17500066
17620599
|
ARRB1
|
COF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17500066
17620599
|
SSH1
|
1433Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27432908
28514442
19371722
28675297
|
HSPA4
|
PARK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IMPDH1
|
IMPDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
PAK2
|
PAK3
|
â—¼ CORRELATES
|
|
+
|
0.87
|
0.87
|
CCLE
|
31978347
|
LIMK1
|
1433Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12323073
12361576
|
YWHAZ
|
KIF23
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8397056
22580824
|
MMS19
|
RTEL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
COF1
|
1433Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15161933
12323073
12361576
|
1433Z
|
KIF23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
15161933
20451386
14676191
28514442
31586073
|
YWHAZ
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
1204662
8005727
11526496
|
BAD
|
1433Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19427857
11410287
25770209
33961781
25266655
31980649
23397142
11526496
17389761
20936779
21076048
11697890
21988832
19667065
28514442
|
1433Z
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
15161933
15324660
31980649
17353931
26496610
27684187
27034005
28205554
28628118
28514442
17979178
32707033
|
1433Z
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
15161933
15324660
17353931
29100370
28514442
32707033
|
LIMK1
|
COF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17500066
11925442
12963706
16456544
10436159
17853892
11418599
9655398
19424295
15220930
23082153
16278681
16713569
20133759
23093407
11340065
32015554
|
ARRB2
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
17353931
24069330
28514442
17620599
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
PAK4
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23642861
11950587
11278822
|
BRAF
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
HDAC2
|
CHD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21670149
28977666
26344197
24981860
21258344
9790534
22939629
11003653
9804427
12493763
23752268
32744500
30737378
10545197
26949739
9885572
|
PAK1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10652353
10559936
11340065
|
LIMK1
|
SSH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
RHOC
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
ROCK2
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
LIMK1
|
RHOA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
LIMK1
|
ROCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
LIMK1
|
RHOB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
LIMK1
|
SSH1
|
â—¼ COLOCALIZATION
|
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
SSH1
|
LIMK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
PAK6
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25714010
26375402
28007610
|
RHOA
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10617617
9854026
12810709
|
PAK6
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK14
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15649893
|
RHOA
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
PAK4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
5217174
15324660
|
BAD
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
HSP90AA1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
MAPK1
|
MAPKAPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.9
|
STRING
|
36370105
|
MAPK1
|
MBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
RHOA
|
ROCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
11350930
31871319
|
RHOB
|
ROCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
31871319
34079125
|
YWHAZ
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5217040
15161933
|
CHD4
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
RHOA
|
ROCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PAK1
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
23455922
32707033
31980649
|
ROCK1
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31871319
14660612
31431478
8816443
21281639
8798490
12773565
|
BRAF
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
CFL1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
MAPK14
|
MAPKAPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
POLR2B
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC42BPA
|
LIMK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11340065
11413130
11950587
|
ROCK1
|
LIMK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
23082153
11018042
11171090
11340065
10652353
|
ROCK2
|
LIMK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11340065
11171090
19099536
11018042
|
CDC42BPA
|
LIMK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11413130
10559936
11950587
11018042
11171090
10613909
11340065
10461188
|
LIMK2
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
10559936
17522712
8079118
9655398
11418599
19413330
18578522
20068231
11925442
11340065
18491316
18669648
22154077
11413130
16505165
24509905
15866889
11950587
11171090
19651622
20058876
18702456
25784483
10613909
10461188
|
PAK5
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
28007610
10880354
15226424
10521512
15972258
23162742
9381178
12897128
20567954
16403219
15037618
10837486
|
PRKACA
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
19651622
17081983
1359877
18767875
17322306
18691976
4092695
19664994
20068231
18707149
23429703
11986331
17206380
14991569
19664995
18669648
33771897
|
MAPK1
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10659854
12438317
15890648
|
MAPK1
|
MBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
11258664
17255944
12760422
10371216
12944901
1939237
9792705
16401070
15380617
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
MAPK1
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
MAPK14
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
PAK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
39.0
|
1.0
|
ACSN
|
10230394
10461188
10467124
10511705
10558990
10559936
10611223
10613909
10661401
10837486
11018042
11062502
11121431
11340065
11385609
11413130
11493700
11907067
11950587
12054568
12885870
12954615
14749719
14764585
15157156
15229651
15280015
15536084
15713627
16293614
16702231
17270021
17522712
22154077
8625410
8929531
9346240
9381178
9843499
|
PRKACA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
11983683
10880354
20166139
9346240
11493700
9381178
18794113
12931191
15280015
10230394
10558990
8929531
18669648
10837473
10837486
10611223
12954615
10949026
10851172
15123689
18707149
16403219
17270021
|
PAK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
27121078
20166139
22096607
9346240
18823547
11493700
9381178
23650610
15280015
10230394
10558990
8929531
25225063
18669648
10837486
10611223
23109003
12954615
10949026
16413544
19465939
18707149
15784622
17270021
|
PRKACA
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11510412
10931830
|
PAK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17192257
15710605
10205168
25733387
|
MAPK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
16508002
19710016
19933846
15664191
29335436
8621729
|
BRAF
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17353931
8668348
15324660
15161933
|
MAPK14
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
14970175
33176141
29414778
|
CASP3
|
ROCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11283607
|
CASP3
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9712143
9171063
11070003
9786869
16204230
|
CDC42BPA
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11018042
11340065
11413130
11950587
17522712
22154077
|
CDC42BPA
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
22154077
11413130
10559936
17522712
11018042
11950587
10613909
11340065
10461188
10652353
|
LIMK1
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
10652353
11698448
21178402
9655398
|
SSH1
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12684437
21525957
14531860
10592173
16713569
11832213
16230460
|
LIMK1
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
74.0
|
1.0
|
Omnipath
|
11784854
16456544
10559936
17522712
25814227
8079118
9655398
17853892
11418599
16713569
19413330
18079118
27153537
19424295
23093407
18578522
12963706
20068231
10592173
11925442
10436159
11340065
18491316
18669648
22154077
11413130
12361576
15866889
11950587
19651622
20058876
18702456
16278681
25784483
15220930
29605806
10613909
20133759
10461188
|
LIMK1
|
CFL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19651622
17081983
12684437
8079118
20068231
9655398
19413330
8824278
|
HSP90AA1
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
23220880
30854046
28274957
18039657
16843263
26545934
22046346
23843458
30314968
23948973
|
ROCK1
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10652353
11698448
12194823
12778124
19349987
27785353
|
PAK1
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
28.0
|
1.0
|
ACSN
|
10461188
10467124
10511705
10559936
10613909
10661401
11018042
11062502
11121431
11340065
11385609
11413130
11907067
11950587
12054568
12885870
14749719
14764585
15157156
15229651
15536084
15713627
16293614
16702231
17522712
22154077
8625410
9843499
|
PAK4
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11018042
11340065
11413130
11950587
17522712
22154077
|
PAK2
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16837009
17145710
|
ROCK1
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
22154077
15660133
11413130
10559936
12778124
17522712
11018042
11950587
10592173
10613909
10436159
11340065
26169470
10461188
10652353
|
ROCK2
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22154077
11413130
10559936
12778124
17522712
11018042
11950587
10613909
10436159
11340065
12919678
10461188
10652353
|
PAK1
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
22154077
11784854
15660133
11413130
10559936
23550835
17522712
11018042
11950587
17981134
10592173
22458949
10613909
11340065
25721396
10461188
10652353
|
PAK4
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22154077
28007610
11413130
10559936
17522712
11018042
11950587
10613909
11340065
16641196
10461188
|
MAPKAPK2
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21297993
25134715
16456544
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAPK1
|
TPPP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15822905
17693641
18669648
19413330
|
MAPK1
|
MAPKAPK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
21675959
22028470
15094067
8846784
23047924
25255283
12861023
7592979
1327754
8995385
|
MAPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19604315
15542607
16964243
15212693
11604394
|
MAPK14
|
MAPKAPK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
21675959
16456544
23602568
17395714
21988832
10581204
23331499
21071413
27898710
23047924
10922375
12738796
11551945
26496610
25852190
18988627
15629715
18669648
15187187
11042204
26186194
25241761
8846784
17906627
14499342
9922370
7923353
9768359
18039929
25255283
7592979
17255097
11274345
23455922
|
MAPK14
|
PAK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15550393
|
MAPKAPK2
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9705322
16376338
11956222
12861023
|
PRKACA
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12654918
21572420
20591975
8599934
16109481
34088899
11162591
15890975
|
PRKACA
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
29109150
11956222
12861023
16376338
19451227
|
ROCK2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11283606
15699075
8816443
11294240
8617235
|
RHOA
|
ROCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11698448
11729192
11739775
11992112
12194823
12361600
12740575
14657501
14744429
15761148
17517963
18037882
18423981
20535745
21178402
22949611
24857661
24919149
26885855
27048821
27066895
7479854
9362522
9660866
9822605
|
RHOA
|
ROCK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23109003
12727213
17673200
17446864
11350930
|
RHOA
|
ROCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17145710
12361600
25010901
23151663
7479854
27048821
22949611
21281639
26885855
8798490
12727213
17673200
11729192
8816443
10592173
11698448
27066895
11739775
11992112
20535745
18423981
24857661
21178402
23109003
9660866
9822605
17517963
14660612
15774750
12740575
14744429
9535835
12773565
15761148
24919149
26192618
9362522
18037882
14657501
12194823
|
ROCK2
|
RHOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11283606
15699075
8816443
11294240
8617235
|
ROCK2
|
RHOC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11283606
15699075
8816443
11294240
8617235
|
RAD54L
|
HIST1H1A
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.66
|
1.65
|
PKG
|
28854368
|
RAD54L
|
RAD54L
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.32
|
3.31
|
PKG
|
28854368
|