YWHAZ
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
CYCS
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9267021
5221616
|
APAF1
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
5214497
11550094
|
APC
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
IKBKB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23332762
|
BAD
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15725726
|
CDK1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19917720
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
CASP9
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
AKT3
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
17544405
5219985
|
GSN
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
9323209
9930654
|
CASP3
|
CASP9
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12011067
15573119
|
CASP3
|
DCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11248093
|
DCC
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0901767106
19721007
|
EGFR
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7945309
|
MAPK1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17205132
|
GSN
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CDKN1A
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
IRF3
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21133648
19129183
|
CUL1
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17290223
5219620
|
CHEK1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20639859
8010047
|
YWHAZ
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217069
15225635
|
EGFR
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
YWHAZ
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217069
15225635
|
PTPRG
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
EGFR
|
ARF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24797263
20029029
|
GSN
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GSN
|
LAMTOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
F2R
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK1
|
L1CAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
FGF2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9490736
12750158
|
MAPK1
|
L1CAM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17151951
21080252
|
LIMK1
|
MAPK14
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456544
5218304
|
MAPK14
|
CDKN1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22820251
22569127
|
LIMK1
|
MAPKAPK2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16456544
5218304
|
MKI67
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PAK1
|
GIT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218539
16628223
|
PAK3
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
LIMK1
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
CDC42
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
11804587
|
PAK1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
HRAS
|
TADA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
IRF3
|
IFNA14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19349300
11303025
|
IRF3
|
IFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16410796
|
YWHAZ
|
CAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
ACTB
|
EFNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
JUN
|
ACTB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10840940
11082319
|
ARPC2
|
ACTB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10592173
9600938
|
ACTB
|
ARPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10592173
9600938
|
ARF6
|
KIF23
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
22522702
8395701
|
ITGB1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0807543105
19168626
|
ITGB1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19168626
|
ARPC3
|
ARPC1B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
20404198
0911668107
|
FYN
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PAK3
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8824201
8798379
|
LCP2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6546918
15929943
|
LCP2
|
FCGR1A
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6548125
9716598
|
VEGFA
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12810700
12215529
|
PRKACA
|
ITGAV
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PTPRG
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
CD3G
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
FYB1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9207119
5221556
|
DOCK1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ASAP2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
RRAS
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ASAP1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PAK2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218167
16374509
|
FYN
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
FYN
|
C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
FAS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159908
5219434
|
FYN
|
RRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17474147
|
HRAS
|
EFNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2201922
7478585
|
ITGA4
|
ITGB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12626562
19454690
|
ITGA4
|
ITGB7
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12626562
19454690
|
JUN
|
CASP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18196534
17922191
|
JUN
|
PAK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17182846
23818969
|
JUN
|
MBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20720108
11226757
|
INPP5D
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11786908
6731384
|
CASP8
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16186808
|
CASP8
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11002417
|
CDC42EP1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DCC
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
YWHAZ
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215799
12361576
|
HSP90AB1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17188549
16641196
|
LIMK1
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20133759
0914492107
|
PAK3
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
LIMK1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11276226
10559936
|
CFL1
|
LIMK1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6173882
17853892
|
PTPRG
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
CD4
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD4
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
ITGA1
|
ILK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19397781
26148229
|
MMP14
|
FGFR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20798051
0914459107
|
FGF2
|
FGF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
FGF2
|
FGF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
FGF19
|
FGFR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907812106
19706524
|
YWHAZ
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
PAK3
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
FGFR2
|
FGF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
FGFR2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8008273
18332103
|
HSP90AB1
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IRAK1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18180283
11096118
|
IKBKB
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18180283
11096118
|
ARHGEF6
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218167
16374509
|
PAK2
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20936779
|
GNB1
|
GNAI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7102203
16782902
|
HSPA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215799
12361576
|
CFL2
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
CD3E
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
FGFR4
|
FGF19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907812106
19706524
|
SSH1
|
CFL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12684437
|
L1CAM
|
PLXNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10520994
15121181
|
YWHAZ
|
SSH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19371722
8008908
|
FGF6
|
FGF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18552176
18757403
|
APOBEC3G
|
APOBEC3F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15152192
7600246
|
MAPK14
|
MAPKAPK2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
14499342
|
CCND1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
EFNA1
|
EPHA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
9330863
|
ARHGEF6
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
POLR2B
|
RPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ITGA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
KIF23
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ARPC5
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
24981860
|
ITGA2
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
CDK5
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
ARPC1A
|
ACTR2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
CUL4B
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
28225217
|
CUL1
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22474075
|
EGFR
|
ILVBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
24189400
|
EGFR
|
PTPRG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
25970784
|
EGFR
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22366308
31980649
|
EPHA2
|
EFNA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
7218654
19525919
|
PAK4
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19778628
29100370
|
CRKL
|
DOCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
FYN
|
FYB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
9207119
5221556
|
FYN
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17474147
16636290
|
FGFR2
|
FGFR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EPHA1
|
ELMO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ARRB1
|
ELMO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AP1G2
|
AP1S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16713569
9733768
|
ASAP3
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FGF8
|
SRPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EPHA7
|
EPHA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ASAP3
|
ASAP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IFNA4
|
IFNA8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CCND1
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
ACTR3C
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
CDK1
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
BCL2L1
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9539746
|
FGF2
|
FGFR4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
1385111
|
CDK5
|
CCND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23455922
21654808
33961781
|
CCND1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
26496610
33961781
7903056
21654808
|
CCND3
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
26496610
|
EGFR
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24797263
15657067
|
MMS19
|
RTEL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23585563
22678362
22678361
28178521
|
EPHA4
|
FGFR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16365308
18790757
|
ELMO2
|
DOCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32203420
11703939
|
CDK1
|
CDC25C
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
8119945
|
CDC25C
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
19574738
|
ARHGEF6
|
GIT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
CCND3
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CALM3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BRAF
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
CAP1
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
CCND1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CHEK1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CDC42
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31871319
28628118
28205554
|
ILK
|
ILVBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
23455922
|
ARPC4
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
24981860
|
FGF6
|
FGFR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18199118
14613973
8663044
|
APAF1
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
ITGA4
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
CALM3
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ITGAV
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CASP9
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11242052
8900201
25241761
1067155
15941357
11230124
15507451
18723680
17437405
|
CUL4B
|
HDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
30737378
34026424
25189618
|
ILK
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32707033
17353931
23455922
|
EPHA7
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22036564
33961781
|
EFNA5
|
EPHA8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
11416136
33961781
|
ARF6
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11533043
16189514
11867621
|
ARF6
|
KIF23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22522702
31586073
|
FGFR1
|
FGF9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
14613973
18199118
10574949
|
PAK4
|
PAK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
32707033
33961781
26186194
|
C8A
|
C8G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
CD8A
|
CD8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
APAF1
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
APC
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17145773
21311754
|
ILK
|
MMS19
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17353931
23455922
|
ILK
|
FAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23455922
25852190
|
LIMK2
|
LIMK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
9089416
8980133
|
ROCK1
|
LIMK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23082153
11018042
11340065
10436159
|
FGFR1
|
FGF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18199118
25241761
10574949
22244757
|
CHEK1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
CYCS
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
9390557
|
JUN
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
EGFR
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
CUL4A
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17079684
21145461
32235678
|
HRAS
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
34591642
|
HRAS
|
BRAF
|
â—¼ PROXIMITY
|
✅
|
|
0.87
|
0.87
|
mint
|
30194290
|
CASP3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FAS
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CASP8
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
HSPA4
|
PARK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
GNAI2
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IMPDH1
|
IMPDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AP1G2
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ACTB
|
CFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
APC
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20509626
18786926
|
CFL2
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8153045
21516116
|
EPHA4
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31413325
16189514
16713569
12084815
|
PAK2
|
GIT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17353931
26496610
|
YWHAZ
|
KIF23
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8397056
22580824
|
FGF19
|
FGFR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19706524
10525310
|
EPHA4
|
EFNA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10366629
33961781
19836338
|
MMS19
|
RTEL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
CRKL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ITGA1
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
26320552
|
YWHAZ
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
1204662
8005727
11526496
|
CASP9
|
DCC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11248093
16537496
19721007
|
CDK1
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9988268
12372621
25218637
|
CUL4A
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17041588
31973889
23555860
18593899
33961781
16964240
21145461
30945288
32140073
|
EGFR
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
12522133
25402006
|
EGFR
|
LCP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
ARF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
24797263
20029029
31980649
|
EGFR
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
25402006
18271526
25754235
16729043
23397142
|
EGFR
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EFNA1
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14692877
7973638
8755474
19573808
20505120
8139691
22244754
19525919
|
SSH1
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
11832213
|
CAP1
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
8761950
33961781
34079125
|
EFNA5
|
EPHA7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10366629
22036564
33961781
28514442
|
ARF6
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11533043
16189514
11867621
|
GAB2
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9660791
11334882
10871282
|
EPHA8
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16713569
10498895
|
FGF23
|
FGFR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22393163
27879395
19966287
17086194
|
CDK5
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
33961781
26186194
23602568
23455922
|
EPHA4
|
EFNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8755474
16189514
19836338
10366629
|
EGFR
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EFNA5
|
EPHA5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9330863
|
IRAK1
|
IRAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CCND3
|
CDKN1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
APC
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10200466
17297457
9973322
|
PAK4
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23642861
11950587
11278822
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
ACTB
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
EGFR
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
23956138
24658140
25402006
18271526
15657067
|
HSP90AB1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15664193
9844631
20018861
|
ACTB
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GNB2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
GNB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CUL4B
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19651607
33969670
33357448
28225217
24292684
25189618
21145461
18593899
26496610
16678110
16964240
33536335
27113764
29499938
30898011
28886238
29738775
17392787
29846670
22939629
22038470
34026424
16949367
31911655
28446751
17041588
23238014
31973889
16861906
33961781
30945288
26344197
32140073
|
CUL4A
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22952844
17079684
22118460
15448697
26613412
22910413
25349427
21145461
22474075
27462452
16473935
15811626
18606781
26231201
18593899
16678110
16964240
33536335
19295130
25982117
33759138
16260596
27113764
21113133
30898011
28886238
26976604
27203177
17392787
25795299
22939629
26344197
14739464
27294876
10585395
27573245
31911655
17041588
20870715
27203182
31973889
32235678
16861906
19966799
22342275
34251884
17626091
19287380
30945288
16949367
32140073
|
EGFR
|
NRG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7730382
25402006
31980649
24658140
|
EFNA5
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20228801
20505120
9245480
33961781
|
BRAF
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
ARF6
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17363898
16452216
15210957
|
MAPK1
|
AMPH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15262992
|
PAK6
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK14
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15649893
|
PAK1
|
ARHGEF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PAK1
|
LIMK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10559936
11340065
10652353
|
HRAS
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
IRF3
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20483755
27337441
|
L1CAM
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16904324
11222639
17223356
|
EFNA5
|
EPHA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8755474
33961781
19836338
23812375
|
ASAP2
|
ARF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10022920
10749932
|
FYB1
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
9207119
5221556
|
YWHAZ
|
LCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
17353368
8007777
20062066
|
LCP2
|
FYB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
9207119
5221556
|
ITGAV
|
VEGFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12820653
19267251
17030947
|
FYN
|
DCC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15557120
15494734
15494732
|
PRKACA
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20658524
|
IRAK4
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24735611
12860405
19166926
18221795
12538665
17785851
11960013
16024789
16951688
17276401
21903422
|
PAK3
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
HRAS
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
HDAC2
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23752268
9790534
9804427
11003653
22939629
30737378
28977666
26949739
32744500
21258344
24981860
21670149
12493763
9885572
10545197
26344197
|
CASP1
|
IL18
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
1574116
9121587
8999548
|
PAK6
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
31980649
11773441
20936779
32707033
|
PAK2
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
25416956
9535855
17353931
20696164
10320322
20936779
9822598
16204230
32707033
31871319
21311754
|
PAK4
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32707033
16189514
29734338
17353931
11756552
31478661
20936779
9822598
26598620
31871319
26344197
|
ARHGEF6
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15649357
15306850
25241761
|
DIAPH1
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
LIMK1
|
SSH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
LIMK1
|
ROCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11018042
16219803
10652353
|
LIMK1
|
SSH1
|
â—¼ COLOCALIZATION
|
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
SSH1
|
LIMK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
15660133
7600543
8217581
|
PAK6
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25714010
26375402
28007610
|
CD8A
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
CD8B
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15136729
15534202
16551255
|
ITGA2
|
ILK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
11112697
25100717
9456329
|
ILK
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18252715
|
FGFR1
|
FGF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10748122
16829530
9174056
19627396
7520751
23597563
15096041
10950949
11030354
7730326
8609172
21693575
17086194
23597562
10574979
1697263
10490103
1722683
11786412
26267536
15548653
14505356
22539306
1709094
8868466
19696444
8692946
18199118
14613973
|
CASP1
|
FGF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18329368
|
FGF22
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16597617
|
PAK4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
5217174
15324660
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
GNA13
|
ARHGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11313914
15951850
22661716
|
BAD
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CDC42
|
PAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
ACTB
|
CFL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
CDK1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
MAPK1
|
MAPKAPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
FAS
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
11717445
5214823
|
CASP8
|
FAS
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
5219431
17159907
|
FAS
|
CASP8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
16498403
5218359
|
MAPK1
|
MBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CDC42
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
YWHAZ
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5217040
15161933
|
CDK1
|
HIST1H1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
CD247
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CASP8
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
CDC42
|
PAK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
CCND3
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CD3E
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
F2
|
F2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
EFNA2
|
EPHA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
CHD4
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
B2M
|
CD8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
PAK1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5220560
7744004
|
AP1M1
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
26496610
33961781
22939629
26344197
|
CD3G
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
20890284
9582308
2138083
|
FGF2
|
FGFR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
AP1M1
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
AP1M1
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
ARF6
|
KIF23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
APC
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
C6
|
C8G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
C6
|
C8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
PAK1
|
PAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
32707033
23455922
31980649
|
PAK1
|
GIT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
11157752
31980649
16628223
25852190
|
EFNA5
|
EPHB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
BRAF
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
FGF2
|
FGFR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
CDC25C
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
CDC42
|
PAK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15824104
20936779
11157984
|
AP1G2
|
AP1S2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16713569
9733768
26496610
33961781
|
FGF23
|
FGFR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
EFNA5
|
EPHA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
CDC42
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
PAK1
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9535855
11157984
21029865
16678097
19596003
23455922
9705280
31871319
25150978
12879077
12606577
10360579
31478661
10684602
8107774
21048135
23175184
18057010
10802735
21167153
15548653
12650940
18426980
7744004
20936779
24276241
|
ARPC4
|
ARPC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
32296183
23148219
11162547
22863883
33961781
24981860
22939629
26344197
|
ARPC3
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
23148219
26655834
22863883
33961781
24981860
26186194
22939629
26344197
|
FGF2
|
FGFR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
1697263
28514442
11121055
10950949
11390973
9700203
33961781
18199118
26267536
10830168
17981115
|
ARPC1A
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CDC25C
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
EFNA1
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EFNA5
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
BRAF
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
ARPC2
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
11805826
26655834
22863883
24981860
22939629
26344197
|
ARPC2
|
ARPC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
11805826
11162547
22863883
33961781
24981860
22939629
26344197
|
CFL1
|
LIMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
B2M
|
HLA-G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
ITGA5
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
GNAI2
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ARPC2
|
ARPC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
11805826
23148219
22863883
33961781
24981860
9230079
26186194
22939629
26344197
|
ARPC4
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12451597
11162547
26655834
22863883
33961781
24981860
22939629
26344197
|
MAPK14
|
MAPKAPK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC1B
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC2
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB5
|
GNG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB5
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB1
|
GNG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL4B
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC42
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC4
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC3
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2B
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ACTR2
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
PAK1
|
ACTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16293614
10467124
14749719
9843499
16702231
10511705
12054568
8625410
|
CYCS
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
11753565
10393175
10364241
15829969
16977332
15907471
10722681
9390557
10578178
16713569
9267021
12147322
10206961
10329646
11112785
10940292
|
CASP3
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12874265
21827945
11550094
|
BCL2L1
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
10811864
9488720
12963020
9539746
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
APC
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
APC
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
JUN
|
â—¼ SHARES_COMPLEX
|
|
|
33.0
|
1.0
|
ACSN
|
11274345
11955436
11967263
12051714
12711682
15001769
15327769
15834423
16039586
16510874
16547505
16940750
17143292
17439715
17936032
19216735
19506021
19619488
19623618
19751508
20006983
20705860
20964627
21285352
21681822
22270359
23343194
24023259
25730849
26587781
7542250
8545107
8666229
|
APC
|
CUL1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
PRKACA
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11050185
11166179
15649893
11689703
|
PAK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
39.0
|
1.0
|
ACSN
|
10230394
10461188
10467124
10511705
10558990
10559936
10611223
10613909
10661401
10837486
11018042
11062502
11121431
11340065
11385609
11413130
11493700
11907067
11950587
12054568
12885870
12954615
14749719
14764585
15157156
15229651
15280015
15536084
15713627
16293614
16702231
17270021
17522712
22154077
8625410
8929531
9346240
9381178
9843499
|
CDK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12049737
14551205
15279786
17303408
17660363
18414028
18590585
21725609
7575488
|
PAK5
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
28007610
10880354
15226424
10521512
15972258
23162742
9381178
12897128
20567954
16403219
15037618
10837486
|
CDK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
18071308
16166315
24677263
12965220
15907327
26287183
21858202
25618528
12049737
16009721
19124971
16403219
17498878
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
PAK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
27121078
20166139
22096607
9346240
18823547
11493700
9381178
23650610
15280015
10230394
10558990
8929531
25225063
18669648
10837486
10611223
23109003
12954615
10949026
16413544
19465939
18707149
15784622
17270021
|
PRKACA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
11983683
10880354
20166139
9346240
11493700
9381178
18794113
12931191
15280015
10230394
10558990
8929531
18669648
10837473
10837486
10611223
12954615
10949026
10851172
15123689
18707149
16403219
17270021
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
BCL2L1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
25241761
9539746
|
BCL2L1
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16713569
9192670
|
CASP3
|
DCC
|
â—¼ CLEAVAGE
|
✅
|
|
4.0
|
1.0
|
Reactome
|
11248093
16158190
15310786
9796814
|
MAPK14
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
14970175
33176141
29414778
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
CASP9
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10708865
9390557
10508159
11230124
18723680
15657060
16977332
15507451
1067155
9708736
25241761
8900201
11242052
9765224
17437405
19788417
9812896
12620238
15941357
12181739
19465923
12792650
15725726
|
CASP3
|
GSN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9323209
9930654
9671712
|
CASP3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25241761
9660939
10022118
9799125
|
CASP3
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9712143
9171063
11070003
9786869
16204230
|
CASP3
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9367996
11741536
|
CASP3
|
ROCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11283607
|
CASP9
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9390557
25313070
20462491
27697150
|
PRKACA
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
29352269
15703181
|
AKT3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9812896
|
CYCS
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19788417
16977332
9390557
16713569
12147322
12773388
10329646
12792650
15210107
|
CDK1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
19081073
19016842
16287866
29844931
19586613
29416675
17466630
12792650
|
MAPK1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
44.0
|
1.0
|
Omnipath
|
15547943
20080742
12040186
18083711
15173823
12697810
11940578
19081073
19586613
16227978
12738796
16039586
17466630
17255949
18669648
16888006
15187187
19016842
19541618
19091303
19565474
17052211
18039929
18775330
10601235
12792650
11431469
|
JUN
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
16393119
21135252
8917510
17166846
19622016
11402335
20220142
22853846
17670745
10567390
17496887
19499154
9878062
21474819
17278098
15282324
15467760
15994313
14672732
15574422
22550166
10066798
17637753
20482821
15574764
11745411
11410592
18084253
20037604
12794082
10790372
16860316
24190040
17501623
17477349
19435822
10500157
11432833
|
HDAC2
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
15713663
|
CDKN1A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
26203195
23443559
17145710
25416956
7478582
9837900
21988832
21516116
7777546
15232106
16082198
27107012
15695403
8657154
8242751
23007395
9106657
12383116
17556661
8756624
8662825
31515488
|
JUN
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18813803
19219074
16406505
16880536
16054035
19190345
17000779
17439715
8545107
16396903
11274345
20107231
|
CDK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
CDKN1A
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9467962
26186194
21308745
15340381
23602568
23543736
24218572
17679094
15077146
26496610
12973835
|
CDK1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20937773
|
CDK1
|
LATS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17145710
12372621
25482410
18691976
25218637
23985307
15688006
9988268
|
CDK1
|
NUP98
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21335236
25247763
|
CDK1
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20798862
19837665
18691976
21765472
21907702
29092815
18983824
16629900
22686412
24242917
|
CDK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
17349584
17110335
17303408
18073536
1075565
11836499
15279786
8348613
7575488
20668692
24710276
9733650
12036951
20068231
8440392
12742231
32075732
16189514
9141461
16123593
18669648
19652693
18590585
9585407
12814430
10864927
10373560
18691976
11313986
12124778
18786381
17660363
18272572
8119945
15917306
27038604
9268380
17596790
28396830
17568790
19350548
16964243
10037602
18212344
12478465
12766774
|
CDK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
31980649
8360196
23956138
15901825
28150246
18271526
15657067
24658140
25402006
15302935
|
JUN
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11136975
12717415
21278055
10506225
19628677
12054510
18094076
10072388
18210215
10733944
|
AKT3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12851486
15023346
19216069
17680028
11756412
16680151
20214616
11463845
23109003
20452955
9829964
20398329
17646672
10217147
|
MAPK1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20519948
19364816
28368408
|
MAPK14
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23745637
12058028
|
CDKN1A
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
21988832
23443559
26186194
25241761
27107012
8756624
25416956
16328436
31515488
16189514
15232106
32296183
23880157
26496610
9716181
|
CHEK1
|
CDC25C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
15459660
15798197
17102137
17116885
17296725
17384638
17568790
17582221
18677104
19793801
20126263
|
CHEK1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
29774099
17145710
10391675
18321553
29425806
10214922
20716119
18677104
20860841
15798197
19793801
11836499
10681541
21152443
12505356
27603133
24505404
11333986
9836640
11551930
17097061
23880065
15736430
26485758
11240139
9889122
20068231
17116885
12742231
28442587
17582221
20126263
14681223
9278511
17384638
15629715
12814430
11313986
11741534
20068082
24079846
26542114
9278512
9659898
15705874
11027648
24525428
9914179
10557092
15459660
10676638
9810229
15150265
10209160
17296725
15296723
25512053
12399544
21035467
9543386
9744884
19490919
28396830
17102137
17568790
16488126
16330544
12478465
|
CUL4A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
DDB1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
JUN
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16170369
23455325
15923621
16423552
10803405
18604200
|
CAMK2A
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
17389395
17081983
3138233
20166139
10347170
15901825
16799092
18691976
8226933
20068231
1309762
7805884
92065884
1956339
7505275
18669648
15302935
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
MAPK14
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15187187
18039929
19138820
7535770
12738796
17139251
16932740
23397142
16785992
11274345
|
EGFR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31980649
23397142
18271526
24658140
25402006
16729043
|
EGFR
|
CALM3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
19901323
20029029
16497976
15592455
25402006
17389395
18578522
16799092
20068231
7925415
3415247
8639568
18669648
12153558
24658140
17287340
2843348
14960328
18707149
17016520
|
EFNA5
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
20228801
9245480
24003208
15114347
22570727
11114742
9330863
20505120
|
EFNA4
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10607706
23331499
24003208
15114347
9576626
8755474
11114742
9330863
|
EFNA1
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8139691
20505120
23331499
11248553
14692877
24003208
7973638
8755474
18988627
15114347
9576626
22244754
9330863
19573808
11114742
19525919
|
EFNA2
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
10072375
11114742
8755474
18988627
|
HRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
FGFR4
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
FGFR1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
FGF19
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
FGFR2
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
MAPK1
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
31434245
22955283
12748172
16009132
|
MAPK1
|
FGF23
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
19652666
12419216
18452557
12974390
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAPK1
|
TPPP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15822905
17693641
18669648
19413330
|
MAPK1
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8072547
11313929
15378002
12531896
12853483
23720779
9662434
1496019
17570479
1922387
11278277
11739718
16023596
20086174
25557171
7737130
26755651
8224842
14676207
17920329
25201974
9022811
22327296
18650425
8137421
18443042
12881422
18572021
17001009
33767435
7744008
23616010
26745678
14617628
11432833
16819515
22606284
12040039
|
MAPK1
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10659854
12438317
15890648
|
MAPK1
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
27342992
23405013
|
MAPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19604315
15542607
16964243
15212693
11604394
|
MAPK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
16508002
19710016
19933846
15664191
29335436
8621729
|
MAPK1
|
GAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12008033
15356145
|
MAPK1
|
MBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
11258664
17255944
12760422
10371216
12944901
1939237
9792705
16401070
15380617
|
MAPK1
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
24342355
17290218
|
MAPK1
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
MAPK1
|
MAPKAPK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
21675959
22028470
15094067
8846784
23047924
25255283
12861023
7592979
1327754
8995385
|
FYN
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15735648
|
MAPK14
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
PAK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15550393
|
MAPK14
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
14970175
|
MAPK14
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15187187
18039929
18411303
12738796
20626350
11274345
|
MAPK14
|
MAPKAPK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
21675959
16456544
23602568
17395714
21988832
10581204
23331499
21071413
27898710
23047924
10922375
12738796
11551945
26496610
25852190
18988627
15629715
18669648
15187187
11042204
26186194
25241761
8846784
17906627
14499342
9922370
7923353
9768359
18039929
25255283
7592979
17255097
11274345
23455922
|
MAPK14
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
15150265
10744722
9836640
9543386
12941695
20068231
9278512
10681541
16189514
15791647
11551930
9278511
11333986
15629715
10557092
|
MAPK14
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12475989
17689131
17570479
25483191
|
MAPKAPK2
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9705322
16376338
11956222
12861023
|
MAPKAPK2
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21297993
25134715
16456544
|
MAPKAPK2
|
ARPC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18725535
12829704
20068231
22792454
|
MAPKAPK2
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9543386
15629715
|
LCP2
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19124833
9989831
15548136
19574218
|
PAK1
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
28.0
|
1.0
|
ACSN
|
10461188
10467124
10511705
10559936
10613909
10661401
11018042
11062502
11121431
11340065
11385609
11413130
11907067
11950587
12054568
12885870
14749719
14764585
15157156
15229651
15536084
15713627
16293614
16702231
17522712
22154077
8625410
9843499
|
ARHGEF6
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23455922
11157752
9659915
10592173
15688026
21900206
|
CDK5
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
20058876
17114649
12176333
12950086
19298660
19664994
12176334
15542607
19413330
23537649
19036346
19664995
21825040
11604394
|
CDC42
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
810774
10360579
21167153
8107774
10559936
9705280
12650940
16678097
23331499
21029865
10684602
18057010
15020669
21070974
11340065
21048135
15003621
20936779
10934474
11413130
15788770
15713627
9535855
23109003
11950587
19628037
7744004
12879077
12606577
24276241
10224076
19596003
8973630
19812368
11248548
10802735
18719708
10613909
10461188
23455922
|
PAK1
|
ILK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22521536
25738875
27642646
17420447
|
PAK1
|
CASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15561713
|
PAK1
|
ARPC1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
28007610
20603326
14749719
25472536
|
PAK1
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
22154077
11784854
15660133
11413130
10559936
23550835
17522712
11018042
11950587
17981134
10592173
22458949
10613909
11340065
25721396
10461188
10652353
|
PAK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17192257
15710605
10205168
25733387
|
IRF3
|
IFNA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11846978
11884139
12242290
9786932
9707562
12821121
16380379
17785777
9446577
10692430
|
IRF3
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
84.0
|
1.0
|
Omnipath
|
19108859
22911767
20453844
22684309
15857993
17540767
16699525
9891032
24185615
12885884
16125763
19349300
20581830
11846976
20610716
16954376
23911869
9707562
12821121
18851954
26483348
23096996
12604599
12829834
22065573
19176627
9649509
20375222
24180280
27481269
18539711
21492741
19570869
20048166
16641293
20304918
15955070
25531393
18641315
19153231
24257594
20130065
16186222
15699120
12077266
17785777
17243100
22285490
9877175
11303025
22417706
23843640
21148557
18225953
17692882
21281747
11222729
9541017
20660350
21228327
17652396
18614628
19541850
20083668
24532789
22902624
18272195
17079289
21632562
17079305
17496231
22083261
10938111
19846511
10848607
17845078
9446577
10692430
18309294
20483755
17947522
24656046
17296604
|
IKBKB
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25070846
20604809
9566918
14703513
19153595
27992402
18272581
16914100
|
PRKACA
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
19651622
17081983
1359877
18767875
17322306
18691976
4092695
19664994
20068231
18707149
23429703
11986331
17206380
14991569
19664995
18669648
33771897
|
DIAPH1
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
12805219
18001770
12732141
12429848
18923426
|
ACTB
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
24914801
15507212
16439214
22608513
|
ACTB
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
8913641
25416956
15364581
10592173
19704022
16189514
31515488
32296183
16713569
29892012
10980704
|
CALM3
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
EFNA5
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
24003208
15114347
1510785715107850
15107857
|
EFNA5
|
EPHA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
933086311416136
23331499
24003208
15114347
9576626
11114742
9330863
11416136
|
EFNA5
|
EPHA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
11114742
18988627
10366629
|
EFNA5
|
EPHA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
18988627
9576626
8755474
11114742
23812375
9330863
19836338
|
EFNA5
|
EPHA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
11114742
18988627
10531456
9330863
|
EFNA5
|
EPHA6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9576626
11114742
9330863
|
VEGFA
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
FYN
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
11062502
12218089
12731048
15536084
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
ARPC1B
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC2
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ITGAV
|
ITGB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGAV
|
ITGB5
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGB5
|
DOCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGB5
|
ITGA2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
22470492
24309651
26519775
9295024
9763615
|
ITGB5
|
ITGA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
22470492
24309651
26519775
9295024
9763615
|
PAK4
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
28007610
16189514
20507994
12356872
|
LCP2
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19124833
9989831
15548136
19574218
|
CD247
|
LCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
GAB2
|
LCP2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
10849428
10982827
11572860
12640133
16212621
19909365
|
FYN
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10648627
9047237
|
GAB2
|
LCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15286727
23109003
12640133
11323691
|
PAK5
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
11756552
12032833
16189514
32296183
|
IRAK4
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
VEGFA
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
JUN
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9256279
11204570
11353786
23274526
11678207
17341624
20015448
8910439
16328781
11731421
15039660
19553068
20432243
7887961
12163680
10885623
11281649
14602779
18294451
15277220
|
ITGAV
|
L1CAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11553709
19161977
8636223
9003039
|
ITGAV
|
DOCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGB1
|
ITGA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
ITGA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
ITGB1
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
15866889
16919435
17522712
18037882
19161977
19339212
19454690
19487819
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
ILK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18339839
9736715
8538749
16189514
11402068
|
ARPC1B
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC2
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC1B
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC4
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC4
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
HLA-G
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11385609
11438547
11489965
11513144
11875494
11994457
12055234
12731048
12811837
15081523
15778339
16287995
16713974
17100877
20435894
20814939
21059766
22267813
23414611
23508573
24378531
8478617
9603467
9625766
9738502
9751747
|
CD4
|
CD247
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD247
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD247
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
16188976
16282498
10607567
16979207
11160719
10618429
11070003
|
HLA-G
|
CD247
|
â—¼ SHARES_COMPLEX
|
|
|
29.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11385609
11438547
11489965
11513144
11875494
11994457
12055234
12731048
12811837
15081523
15778339
16287995
16713974
17100877
20435894
20814939
21059766
22267813
23414611
23508573
24378531
8478617
9603467
9625766
9738502
9751747
|
FYN
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
11062502
12218089
12731048
15536084
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
B2M
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
10358761
10559964
11154916
11509172
11717192
14508489
16181333
22076556
22790179
24457417
8642276
|
CD4
|
CD247
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CD247
|
GAB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10358138
10562324
10849428
10982827
11353765
11447289
11572860
12138178
12415267
12640133
12707331
12731048
15240681
15699106
15713798
15735648
16212621
17371980
19833085
19909365
20814939
21059766
23414611
23620508
23886063
7600293
8478617
8642247
9625766
9738502
9751747
|
CD247
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10562324
11062502
11353765
11385609
12731048
15536084
20814939
21059766
23414611
8478617
9625766
9738502
|
HLA-G
|
CD247
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
29.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11385609
11438547
11489965
11513144
11875494
11994457
12055234
12731048
12811837
15081523
15778339
16287995
16713974
17100877
20435894
20814939
21059766
22267813
23414611
23508573
24378531
8478617
9603467
9625766
9738502
9751747
|
FYN
|
CD247
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
8578591
12522270
7589084
9677202
9047237
15144186
1454062
1530920
15592455
16094384
9368621
16713569
96108162
15659558
8760790
|
FYN
|
FYB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10229084
10570256
7504057
20661443
25814554
9207119
10497204
24769494
26246585
16713569
23979596
33431658
10409671
17474147
30305305
9748251
|
FYN
|
DOCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15788770
11817894
18212043
18066058
12149262
|
ITGA5
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA4
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
EPHA4
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12084815
23331499
16713569
|
FYN
|
CDK5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
24872417
19901323
9038181
10896159
18691976
20506281
29063113
20068231
16497976
19413330
14757045
12372285
|
FYN
|
DCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15557120
21849478
|
FYN
|
FCGR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8756631
|
IRAK4
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IL18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IL18
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IRAK4
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
17145710
17785851
18252867
17276401
16024789
14625308
15084582
21903422
15292196
25452754
19775907
18221795
15905496
19166926
12538665
12860405
14751757
12496252
11960013
24735611
26143580
17337443
|
JUN
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
26513016
10542237
21069809
15389813
15158360
20225236
12667961
20371366
20511231
20862675
8453101
10202034
18502099
10037779
8830832
19687301
21098092
25567680
20351184
17341596
11120852
21312239
24676671
|
HRAS
|
FGFR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
HRAS
|
FGFR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
HRAS
|
NRG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
HRAS
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17145710
7706312
14970219
18567582
12932319
8073291
1386920
23331499
8601312
9154803
18988627
8668348
21779497
19541618
19933846
17563371
18098337
16803888
26165597
24441586
16135787
12917261
15710605
10545207
|
PRKACA
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
21224395
20166139
18578522
23979717
31562188
18583710
18707149
17603879
19401330
12837751
11533025
|
JUN
|
FGF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9456251
10913304
10559225
11281649
11551904
23485603
23331079
|
JUN
|
IL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
20557936
12370343
10700231
12884855
8436291
9541574
8397339
1737937
9605137
8683110
21832163
9590239
7989759
9774418
16116194
8473495
8114694
10878360
10320367
9233628
7642615
17097050
7565732
8468462
8660843
7739550
8051409
1740667
19181930
|
JUN
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18196534
9873041
9660938
14563113
9710625
11003676
19670268
10811113
9468493
15160330
15546613
12618758
11397794
10744679
|
JUN
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9660935
18035482
22065573
10848607
20048166
22083261
17376932
|
JUN
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11733515
12963547
10903433
19670268
|
PAK2
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21177766
|
JUN
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18813803
19219074
16406505
16880536
16054035
19190345
17000779
17439715
8545107
16396903
11274345
20107231
|
FASLG
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
17145710
8521815
9126929
1375228
1713127
14965271
21803845
9039262
11239407
25241761
9228058
15659383
12753742
7505205
12887920
15725726
|
IL18
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
CASP1
|
IL18
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270365
17039247
15326478
9121587
9334240
|
HLA-G
|
CD8A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1908512
10843658
10809759
|
ITGA5
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
15866889
16919435
17522712
18037882
19161977
19339212
19454690
19487819
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
CDC42
|
DOCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15710388
15247287
12134158
17196961
17027967
|
PAK6
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20936779
11773441
16189514
|
CDC42
|
PAK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
10559936
11756552
29734338
15020669
16189514
11340065
15003621
20936779
10934474
11413130
17353931
22653441
11950587
26598620
11248548
9822598
18719708
10613909
10461188
|
CDC42
|
CDC42BPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17145710
20936779
10934474
10559936
11413130
11950587
11248548
15020669
18719708
10613909
15194684
11340065
15882626
9418861
15003621
10461188
|
CDC42
|
PAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
11157984
20936779
10934474
10559936
11413130
11950587
11248548
15824104
15020669
18719708
10613909
10866202
11340065
15003621
10461188
|
CDC42
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8107774
10559936
25416956
10320322
23331499
15020669
11340065
15003621
20936779
10934474
11413130
17353931
9535855
11950587
19628037
32296183
16204230
20696164
11248548
9822598
18719708
10613909
9823899
10461188
|
CDC42BPA
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11018042
11340065
11413130
11950587
17522712
22154077
|
ROCK1
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10652353
11698448
12194823
12778124
19349987
27785353
|
PAK4
|
LIMK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11018042
11340065
11413130
11950587
17522712
22154077
|
LIMK1
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
10652353
11698448
21178402
9655398
|
CDC42BPA
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
22154077
11413130
10559936
17522712
11018042
11950587
10613909
11340065
10461188
10652353
|
PAK4
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22154077
28007610
11413130
10559936
17522712
11018042
11950587
10613909
11340065
16641196
10461188
|
ROCK1
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
22154077
15660133
11413130
10559936
12778124
17522712
11018042
11950587
10592173
10613909
10436159
11340065
26169470
10461188
10652353
|
PAK2
|
LIMK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16837009
17145710
|
LIMK1
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
74.0
|
1.0
|
Omnipath
|
11784854
16456544
10559936
17522712
25814227
8079118
9655398
17853892
11418599
16713569
19413330
18079118
27153537
19424295
23093407
18578522
12963706
20068231
10592173
11925442
10436159
11340065
18491316
18669648
22154077
11413130
12361576
15866889
11950587
19651622
20058876
18702456
16278681
25784483
15220930
29605806
10613909
20133759
10461188
|
LIMK1
|
CFL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19651622
17081983
12684437
8079118
20068231
9655398
19413330
8824278
|
ROCK1
|
LIMK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
23082153
11018042
11171090
11340065
10652353
|
CD3E
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD3G
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
18037897
26300885
15864273
14764708
20080535
15723809
7542404
21167756
22006319
25703557
|
CD4
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD4
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
FGF2
|
FGFR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11874475
18232728
18633355
18776941
19508171
19631971
21098712
22652804
23123598
25374926
9242465
|
FGF2
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
23331499
18332103
26267536
7687739
16597617
25772309
10830168
11390973
10950949
11121055
17981115
8663044
|
FGF2
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7680645
8530375
16597617
1385111
86630448530375
8663044
25772309
|
FGF2
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
17145710
15096041
8868466
10490103
16597617
11030354
23597562
1722683
14613973
17086194
14505356
9174056
7730326
25772309
11786412
16829530
10950949
23597563
10574979
26267536
|
FGFR1
|
FGF23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
1379698
16507368
8622701
11294897
17086194
|
FGF23
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
27879395
19966287
16597617
16081635
22393163
25772309
|
FGF5
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16597617
83868288386828
8386828
25772309
|
FGF19
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22442730
16597617
25772309
|
FGF18
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10751172
16597617
25772309
|
FGF17
|
FGFR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10751172
16597617
25772309
|
CDC42BPA
|
LIMK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10461188
10559936
10613909
11340065
11413130
11950587
|
CDC42BPA
|
LIMK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11413130
10559936
11950587
11018042
11171090
10613909
11340065
10461188
|
FGF18
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
10751172
16597617
8663044
25772309
|
FGF17
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
10751172
16597617
8663044
25772309
|
FGF19
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16597617
25772309
|
FGF5
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
838682811876253
16597617
8386828
11876253
25772309
|
FGF23
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16597617
16081635
12032146
1608163512032140
|
FGF6
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
16597617
25772309
8663044
|
FGF8
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
10751172
16597617
8663044
25772309
|
FGF22
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
16597617
12591959
8663044
25772309
|
DNM2
|
AP1S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
AP1M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
AP1S2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
DNM2
|
AP1S1
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
DNM2
|
AP1S2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
DNM2
|
AP1M1
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
CDK5
|
TPPP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15822905
17693641
18669648
19413330
|
CDK5
|
AMPH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
14623869
11113134
19584925
|
PAK2
|
ARHGEF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16374509
17392278
32296183
|
GNB1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
GNB1
|
GNG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GNG2
|
GNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
ARRB2
|
GNAI2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
ARRB1
|
GNAI2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
AKT3
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20016067
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
PRKACA
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11510412
10931830
|
PRKACA
|
GNA13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12399457
|
PRKACA
|
APOBEC3G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18836454
|
PRKACA
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
29109150
11956222
12861023
16376338
19451227
|
DCC
|
DOCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15788770
11817894
18212043
18066058
12149262
|
AKT3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10869359
18451171
11293329
19493313
|
BRAF
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17353931
8668348
15324660
15161933
|
EFNA2
|
EPHA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
10072375
9576626
11114742
10531456
9330863
|
EFNA2
|
EPHA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
11114742
9330863
|
EFNA2
|
EPHA6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
10072375
9576626
11114742
9330863
|
EFNA2
|
EPHA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
24003208
15114347
11114742
9330863
19836338
|
EFNA2
|
EPHA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
11114742
9330863
|
F2R
|
GNA13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8290554
20223821
10922491
16189514
22318735
22972936
21331223
|
GNA13
|
ARHGEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
14607242
9641916
9641915
16189514
12681510
|
LIMK2
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
10559936
17522712
8079118
9655398
11418599
19413330
18578522
20068231
11925442
11340065
18491316
18669648
22154077
11413130
16505165
24509905
15866889
11950587
11171090
19651622
20058876
18702456
25784483
10613909
10461188
|
SSH1
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12684437
21525957
14531860
10592173
16713569
11832213
16230460
|
ARPC1B
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
FGF23
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16597617
16081635
25772309
|
F2
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9058715
10978167
15707890
10644723
14652070
11356985
23450633
18250335
12563219
22972936
|
EFNA1
|
EPHA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
8755474
11114742
9330863
|
EFNA1
|
EPHA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
9576626
8755474
11519828
11114742
18988627
9330863
|
EFNA1
|
EPHA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
17420126
24003208
15114347
9576626
11114742
10515610
|
EFNA1
|
EPHA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
8755474
11114742
16189514
10366629
9330863
19836338
|
EFNA1
|
EPHA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
8755474
11114742
16189514
93308638755474
9330863
|
EFNA1
|
EPHA6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
9576626
8755474
11114742
93308638755474
9330863
|
FGF19
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19706524
22442730
16597617
1473096710525310
31529503
14730967
10525310
25772309
|
EFNB1
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
24003208
8878483
15114347
9576626
11114742
93308638878483
9330863
|
EFNB1
|
EPHB6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24003208
15114347
11114742
11713248
|
EPHB2
|
RRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10570155
11682467
|
EFNA4
|
EPHA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
11114742
10366629
19836338
|
FGF6
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
13851111385111
16597617
1385111
25772309
|
FGF17
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10751172
16597617
25772309
|
FGF18
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10751172
16597617
25772309
|
EFNA4
|
EPHA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
11114742
10515610
|
EFNA4
|
EPHA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
11114742
8755474
|
EFNA4
|
EPHA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10607706
23331499
24003208
15114347
9576626
8755474
11114742
9330863
|
EFNA4
|
EPHA6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10607706
23331499
9576626
11114742
9330863
933086310607706
|