Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATP5F1E LIMK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LIMK2 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053785 5219245
LIMK2 HIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
CDC37 SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21900206 2001699 8089645
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
CDK4 HIST1H1A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFL2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LIMK1 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133759 0914492107
CFL1 LIMK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6173882 17853892
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
HSP90AA1 DNAJA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJA2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
SERPINH1 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
HSP90AB1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
HSP90B1 SLC25A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPB1 TTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAK3 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11276226 10559936
LIMK1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11276226 10559936
LIMK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11276226 10559936
PAK3 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
TTC1 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
ROCK2 ROCK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DNAJA2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
LIMK2 FKBP5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
FKBP5 CDK4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25036637 26186194 28514442 32707033
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
ROCK1 LIMK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10436159 11018042 23082153 11340065
LIMK2 COF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10613909 10436159 11418599 9655398 23082153 11340065
LIMK2 LIMK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9089416 8980133 33961781
CRK HSPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 31980649
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
LIMK1 COF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17500066 11925442 12963706 16456544 10436159 17853892 11418599 9655398 19424295 15220930 23082153 16278681 16713569 20133759 23093407 11340065 32015554
PAK4 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 26344197 17353931 31478661 11756552 20936779 9822598 29734338 32707033 16189514 26598620
PAK6 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 20936779 11773441 32707033 16189514
PAK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 32296183 17353931 25416956 20696164 20936779 9822598 10320322 9535855 21311754 16204230 32707033
RPS6KA1 CFL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTK2B CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10329689 16713569
PAK1 LIMK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10652353 10559936 11340065
ROCK2 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
LIMK1 ROCK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
PAK6 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25714010 26375402 28007610
CDC42 PAK3 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CDK4 HSP90AB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CDC42 PAK4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CDC42 PAK6 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDK4 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
PAK1 PAK2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23455922 32707033 31980649
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC42 PAK2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CFL1 LIMK1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDC37 CDK4 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC42BPA LIMK2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10461188 10559936 10613909 11340065 11413130 11950587
ROCK1 LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23082153 11018042 11171090 11340065 10652353
ROCK2 LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11340065 11171090 19099536 11018042
PRKCD LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15923181 16820362 22492986
CDC42BPA LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11413130 10559936 11950587 11018042 11171090 10613909 11340065 10461188
LIMK2 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 10559936 17522712 8079118 9655398 11418599 19413330 18578522 20068231 11925442 11340065 18491316 18669648 22154077 11413130 16505165 24509905 15866889 11950587 11171090 19651622 20058876 18702456 25784483 10613909 10461188
PAK5 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 11756552 12032833 16189514 32296183
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
PAK6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 11773441 16189514
CDC42 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8107774 10559936 25416956 10320322 23331499 15020669 11340065 15003621 20936779 10934474 11413130 17353931 9535855 11950587 19628037 32296183 16204230 20696164 11248548 9822598 18719708 10613909 9823899 10461188
CDC42 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11157984 20936779 10934474 10559936 11413130 11950587 11248548 15824104 15020669 18719708 10613909 10866202 11340065 15003621 10461188
CDC42 PAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10559936 11756552 29734338 15020669 16189514 11340065 15003621 20936779 10934474 11413130 17353931 22653441 11950587 26598620 11248548 9822598 18719708 10613909 10461188
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
CDC42 CDC42BPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 20936779 10934474 10559936 11413130 11950587 11248548 15020669 18719708 10613909 15194684 11340065 15882626 9418861 15003621 10461188
CDC42BPA LIMK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10461188 10559936 10613909 11018042 11340065 11413130 11950587 17522712 22154077
CDC42BPA LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 22154077 11413130 10559936 17522712 11018042 11950587 10613909 11340065 10461188 10652353
LIMK1 CFL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10652353 11698448 21178402 9655398
LIMK1 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 11784854 16456544 10559936 17522712 25814227 8079118 9655398 17853892 11418599 16713569 19413330 18079118 27153537 19424295 23093407 18578522 12963706 20068231 10592173 11925442 10436159 11340065 18491316 18669648 22154077 11413130 12361576 15866889 11950587 19651622 20058876 18702456 16278681 25784483 15220930 29605806 10613909 20133759 10461188
LIMK1 CFL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 17081983 12684437 8079118 20068231 9655398 19413330 8824278
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
ROCK1 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10652353 11698448 12194823 12778124 19349987 27785353
PAK1 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 10461188 10467124 10511705 10559936 10613909 10661401 11018042 11062502 11121431 11340065 11385609 11413130 11907067 11950587 12054568 12885870 14749719 14764585 15157156 15229651 15536084 15713627 16293614 16702231 17522712 22154077 8625410 9843499
PAK4 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10461188 10559936 10613909 11018042 11340065 11413130 11950587 17522712 22154077
PAK2 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16837009 17145710
ROCK1 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 22154077 15660133 11413130 10559936 12778124 17522712 11018042 11950587 10592173 10613909 10436159 11340065 26169470 10461188 10652353
ROCK2 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22154077 11413130 10559936 12778124 17522712 11018042 11950587 10613909 10436159 11340065 12919678 10461188 10652353
PAK1 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 22154077 11784854 15660133 11413130 10559936 23550835 17522712 11018042 11950587 17981134 10592173 22458949 10613909 11340065 25721396 10461188 10652353
PAK4 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22154077 28007610 11413130 10559936 17522712 11018042 11950587 10613909 11340065 16641196 10461188
PRKCD PPP1R14B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12144526 10606530 12804574 16397254