Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
AR HEY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15684393
AR MEF2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23598283 20610535
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
BATF2 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
SOX4 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810147106 19234109
SMAD2 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
MAGED1 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SOX4 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810147106 19234109
NCK1 FOXH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 FOXH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FOXH1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KDR GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MIXL1 GSC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19711456 19038793
SMAD2 GSC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16055724 9702197
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15044954
PRKACA SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511908 6798777
TGFBR1 SMAD2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973958
SMAD4 TGIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
MSX2 TLX3 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
HOXA1 KRTAP19-7 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
OXER1 ZIC1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
ATP23 ZIC1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
FOXH1 OXER1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRTAP19-2 ZIC1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
FOXH1 KRTAP19-6 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
MSX2 ZC3H10 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
FOXH1 PLA2G10 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
ATP23 FOXH1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
FOXH1 KRTAP13-3 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
FOXH1 HDHD3 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
CEACAM6 FOXH1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP11-1 TLX3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
PLA2G10 TLX3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP11-1 PLA2G10 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
C11ORF1 HOXA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HOXA1 KRTAP19-6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HOXA1 KRTAP13-3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
OXER1 ZC3H10 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KLHL26 ZIC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
C10ORF55 UFSP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
FOXH1 UFSP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
C10ORF55 FOXH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP3-1 TLX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LEMD3 SMAD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
KRTAP19-6 TEKT5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
TLX3 UFSP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
PLA2G10 ZC3H10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
OXER1 PRR20C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
OXER1 PRR20D â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
OXER1 PRR20E â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP19-2 KRTAP3-3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
OXER1 PRR20A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
OXER1 PRR20B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
UFSP1 ZIC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP11-1 ZIC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
MDC1 RBM46 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ATP23 HOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CREBBP TCF3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
KRTAP13-3 KRTAP3-1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
MEF2C EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
SMAD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31130994 10199400 14699069 11226163
TGIF1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11427533 32814053 11306568
FOXD2 FOXH1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
KRTAP19-7 KRTAP3-3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
FOXH1 ZIC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CREBBP TCF12 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
TFG GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 18624398
UNG FOXH1 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
HDAC1 TGIF1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
FOXH1 FOXG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10938097 20211142
TGIF1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11371641 10199400
FOXH1 PNMA5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
FOXH1 ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRR20C ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRR20D ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRR20E ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRR20A ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRR20B ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ATXN1L FOXH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOXH1 SMAD2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FOXD2 NOTO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CRX FOXH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SMAD3 TGFBR1 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
FOXH1 MIXL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18336814 15982639 17568773
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
HEY1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16782059 17028039 18694572
SMAD4 MSX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14551209 18334251 10636910
SMAD2 TGFBR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CRX ZIC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FOXH1 PRR20C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FOXH1 PRR20D â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FOXH1 PRR20E â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FOXH1 PRR20B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FOXH1 PRR20A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20C TLX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20D TLX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20E TLX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20A TLX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20B TLX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
LEMD3 SMAD2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CRX ZC3H10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
HOXA1 KRTAP3-3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CRX SOX14 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CRX TLX3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20C â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20C â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20C PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20C PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20D PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXA1 KRTAP11-1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
FOXH1 NC2A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16713569 12471260
XRCC4 FOXH1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AR SOX4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
CREBBP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16751102 18003620 9679056 15750622 17283070 20403362 17074756 15231748
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
FOXH1 NODAL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20227405 17038485 21741376 15459100 12642485
FOXH1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9389648 23331499 21828274 9858566 9288972 16916642 10199400 10938097 12191473 15750622 32296183 12374795 11371641 9702198 12732634
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 KDR â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 KDR â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
KDR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9405464 16966330 10319320
SMAD4 HEY1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 14976548 15265520 16179589 16713975 16831886 18768831 18832382 19208835 19597490 20731704 21042762 21317430 21614932 22331441 8515656 8893010 9389648
SMAD3 HEY1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 14976548 15265520 16179589 16713975 16831886 18768831 18832382 19208835 19597490 20731704 21042762 21317430 21614932 22331441 8515656 8893010 9389648
KDR NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SMAD2 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160896
NCK1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
TGFBR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15657037 9435577
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
TGFBR1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
TGFBR1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 10678166 12220225 9892009 9463378 16024789 9136927 14625308 11792802 11133108 19920116 14557817 11278410 15134444 10085140 23331499 21071413 20060931 17934056 18511908 21614932 18988627 10973958 23221174 8980228 9311995 9346908 9235954 20519943 21900405 15350225 15548370 26057631 19010789 15104092 16474430 9346966 30093905 12957874 11744690 9525694 15212693 11274345 9865696
TGIF1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18511908 10199400 11371641
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
TGFBR1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
TGFBR1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 15104092 9311995 8774881 25714018 11438668 19458083 11792802 12957874 19701891 9380693
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
TGFBR1 SMAD4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
TGFBR1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8774881 20060931 11274345 21614932
MDC1 FOXH1 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
MDC1 NODAL â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368