Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LRRK2 BAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
BAG2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMD4 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMAD3 FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701891 15367216
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
RAF1 BAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8692945 5221106
IRF1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21219575 18641303
PA2G4 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
CHIP TRAF6 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 23322406 21911421 24578159
TRAF6 UB2D2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29643511 19549727 32296183 29326975
PTEN CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31811908 26280536 22427670 34589606
RAF1 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 22350907 25036637 34017080 15936278 19011619 15215316
IRF1 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 30042418 26330542 23729439 28362432 20947504 23134341
ERBB2 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 12574167 33995662 17875712 17239458 26716506 12239347
UB2D2 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20675402 20466727 34057440 14612456 25684577 15936278 23973223 31596601 21518764 28134249 21358815 15447663 28757353 33619536 16275660 19237536 11676916 28431247 22350907 23695783 32723828 29326975 15911628 30107089
P53 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32097779 21268072 26330542 25543083 35140242 30911017 18223694 15911628 22254155 17666403 20618441 15001357 25144556 23134341 27775703 27807478 29953728
ATX3 CHIP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20943656 21625540 21855799 32401531 19153604 29111377 23696636
HSP7C HS71L â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29568061
CHIP SYUA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32430178 18436529 21358815
ILK BAG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 25852190
PRP8 BAG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28515276
BAG2 RAF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
BAG2 DNJB6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25036637 33957083
KLH34 BAG3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BAG3 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 23824909
BAG3 MLF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25036637 26496610
EGFR PSMD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24189400 23956138
EGFR PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
CHIP MLF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
CHIP PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27787517
YAP1 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 31393050
LRRK2 HSP74 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 19826009
ILK HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IRAK1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15647277 29568061
CHIP PA2G4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27464702 24651434
HSP74 PA2G4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27464702 24651434
KLH34 BAG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MTCH2 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 32877691
HSP71 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20048054 1540595
HS90B ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32206096 21730179
KLH34 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TYSD1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ABH15 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DNJC5 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19098309 33957083
ABH15 HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DNJC7 HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33957083 26496610
KLH34 HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HS90A PRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28515276 19875381
TELT HSP74 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TELT CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRP8 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28515276
PSDE CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32723828 22939629
TYSD1 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH34 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ABH15 CHIP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CHIP DYXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19423554 26871637
CHIP TXLNG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
CHIP NADE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
P53 BAG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23443559 22653443 35140242 27807478 25144556
BAG2 DNJC7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33957083 33961781 25036637 26496610
YAP1 HSP74 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24366813 25796446 31501420
TRAF2 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
TRAF2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
P53 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732139 23687300 24157709
RAF1 GCR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11005817 16189514
LRRK2 P53 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24725412 26384650
LRRK2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24947832 31046837 20642453 23075850 17400507
LRRK2 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18367605 24947832 23455607 19826009 29519959 31046837 28320779 24510904 17400507
ILK HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 33961781
AKT1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24462114 31980649 16027165
P53 DNJC7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 23261415 33961781
HSP74 DNJC7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33957083 20661446 18620420 26344197
CHIP DNJB6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22366786 25036637 33957083
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
HS90A LRRK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18367605 24947832 19536328 22612223 19826009 29519959 31046837 20949042 26355680 16321986 23075850 20642453 17400507
ILK CHIP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23455922
IRAK1 CHIP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
JAK3 CHIP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
P53 HS71L â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17184779 31152661 25241761 23443559
CHIP GCR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31182584 20661446 23493285 11146632
CDK20 CHIP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23602568
UBE2N CHIP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16307917 25036637 17426036 23695783 28757353 32022419 26010904 18678647 25225294 25260751 20146531 24023840 21518764
SMAD3 CHIP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14701756 32737199
RAF1 HSP7C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20039095 31980649 16093354
HS90A IRAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 15647277
SYUA HSP7C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21832061 31980649 22776201 17893145 22843682
TAU HS90A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25864199 30382094 27254664 27495389 26269332 20071522
SYUA HSP74 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21985244 17010992 21832061 31980649 21358815 17012257 14711827
UB2V1 CHIP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16307917 18042044 21911421 25260751 26010904 22939629
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
CHIP HSF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16293251 14532117 23344957
TRAF6 UB2V1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18710948 19713527 15327770 19549727 19675569 24610907 15125833 20501938 11057907 29537486 23885119 17135271
CHIP TRAF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 21793045
AKT1 PTEN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12297295 19903340 12077256 28628118 20605778 28205554 10866658 20596030
SYUA LRRK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23183827 19878656
AKT1 TAU â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19014373 17512525 18292230 31358653
AKT1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21767636 18292230
PSMD4 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19240029 11146632 21855799 32723828 22350919 26344197
BAG1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 20675402 26330542 11676916 15538384 16207813
TERF1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21044950 20811636
HS90B HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 16263121
DNJB6 HSP7C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10954706 25036637
HS71L DNJC7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 33957083
DNJC7 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33957083 26496610
DNJC7 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18620420 15189447 20661446 12853476 19875381
CHIP HS71L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 33957083
BAG3 DNJB6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22366786 30559338 25036637
BAG3 CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 31500722 25036637 26496610
BAG3 HSF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27173435 23824909 25036637
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR TAU â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
PTEN P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12620407 16713569 18339852 24141722 14559824
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
FOXP3 CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33209884 23973223
ANDR CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27835608 16725394 21157430 30446660 27903893 15107424 29249800 19706771 20661446
P53 GCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11080152 16189514 11562347 16713569
ANM5 CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33376131 26658161
CHIP HSP72 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 33957083 24981860
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CHIP BAG2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33987175 16169850 25036637 33961781 24981860 16207813
TRAF2 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 16189514 16260598 21782231 16713569 25416956 9500555 33961781 21516116 21903422
LRRK2 CHIP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19536328 29513927 31046837 28320779 19196961 24510904
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
SMAD1 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17183365 23734213
TAU BAG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17954934 33961781
BAG1 HSP74 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11231577 20156966 34428256 11520069 12874020 10671488 19229298 9305631 15603737
P53 HSP7C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7954368 8940078 28215707 23443559 8729618 31152661 31027880 11297531 11707401 25144556 32807901
HSP71 GCR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24949977 12093808
HSP7C DNJC7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25864199 10567422 26496610 27684187 29568061 33957083
HS90B HSP74 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29930177 26344197
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MLF2 BAG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 33961781 25036637
HSP74 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20029029 31980649 24658140 25402006 12006493 18271526
EGFR SYUA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
HSF1 HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 1628823 9499401 9699716 33961781 21784850
HSF1 HSP74 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9222609 14532117 1628823 20565132
TRAF2 UBE2N â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23453969 20047764 23007157 20577214 34117217 11057907 22184250
SMAD1 YAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19914168 21685363
SMAD3 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10518526 12902338
RAF1 HS90A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 24462205 22939624 28537252 28146421 17699868 19011619 8408024 16335536 23118896 25036637 16330544 27703006 16504566 8962087 20159553 32707033 20039095 17409432 15618521 16093354
RAF1 HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 16330544 17979178 34017080 22939624 32707033
LRRK2 TAU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22303461 24113872 26268594
HS90B AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10995457 20650008 31980649
SMAD1 CHIP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14701756 23344957 21454478
HS90B ERBB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939624 28369073 20650008 24189400
BAG1 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23493285 16189514 10477749 9603979 11101523
HS71L HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 33957083
HS90B HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25864199 29930177 26344197
HSP74 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 25864199 33961781 30021884 22990239 27684187 22939629 29568061 18408180 26344197
HSP7C TELT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 23414517
CHIP TAU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14962978 31320752 15447663 32401531 20466727 17304350 23237806 16275660 32022419 14612456 23554879 23696636 18292230
CHIP HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32600329 25036637 32401531 20618441 16293251 32041778
TRAF2 UBE2N â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BAG2 HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 18457437 9873016 33961781 28042827 30021884
BAG2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14978028 12502846 8692945
CHIP EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33775711 20029029 31980649 24658140 25402006 24722501 27475501
EGFR TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 23972990 25402006 18271526
EGFR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32669362 20029029 31980649 16849543 12471035 23956138 16024644 24189400 24658140 12006493 25402006
EGFR HSP7C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 24189400 23956138 24658140 28065597 25402006 15657067
EGFR HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 23956138 24189400 24658140 22939624 25402006 15657067
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
EGFR HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 25241761 31980649 24189400 24658140 25402006 15657067
HSP7C HSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 7639722 33961781 16293251
HS90A HSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12621024 11583998 26517842 22367781 9222609 16278218 20885985 18599869
DNJB6 MLF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33957083 24981860 25036637 23414517
P53 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 9312059 23169665 15044383 12898523 14627987 9565608 32807901
TRAF6 UBE2N â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18710948 17327397 15147900 17709375 21113135 27791197 19810754 24610907 29950522 27695001 27918549 31074699 34490261 18617513 30979779 25548215 11057907 19465916 29537486 31638574 15327770 19549727 31578830 27173435 28244869 29432170 23885119
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
UBE2N TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18981220 14713952
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
BAG1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11231577 16189514 8692945
AKT1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18332867 28708672 16210317 11156376 11404460
PA2G4 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9565586 15583694 12165860
ERBB2 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 24189400 16144943 23995768 24658140 22315411 26804907 18655187 21503962 22939624 21812426 12006493 17239458 20159553 11071886 20558745
BAG1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14517289 11278763 9565586 16713569
ANDR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 16713569 21157430 32206096 27903893 17974989 1540595 26342197 26196320 25500540 19706771 19805354 17353003 1525041
P53 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32097779 16189514 15358769 16713569 21268072 23443559 31152661 11297531 21460846 15004035 22939624 30911017 11507088 11707401 15001357 10557093 12427754 32807901
P53 HSP74 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17184779 32097779 21268072 20847049 15004035 35140242 18223694 30911017 25144556 23109422 32807901
HS90A HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27353360 24949977 11413142 12093808 16263121 21360678 12853476 19875381
HSP71 SYUA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21985244 31980649 19875982
HSP71 CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 32401531 10330192 12150907 16275660 33961781 20618441 28042827 27787517 26010904 22939629 23904609 23271055 33957083
TAU HSP7C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17954934 25864199 33139698 29764935 14612456 26269332 33961781 19654187 18500754
HSP7C CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26232501 27709416 27684187 15215316 25684577 21454478 25036637 16554822 21911421 20618441 23865999 11146634 29568061 15538384 25864199 26264872 28396517 16275660 18988734 16293251 11557750 26010904 27708256 17178836 27283392 15198682 25258038 29317501 10330192 23990462 33961781 16207813
HSP7C HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27708256 16189514 25864199 22504172 26344197 9269769 21360678 20039095 19875381
HS90B TAU â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30382094 24581495 26269332
SYUA TAU â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21985244 10464279 32291284 17408955 32814053 21127069 15904919
HS90A CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23344957 23256568 17317785 21454478 18818696 20661446 12574167 11146632 22824801 20618441 30911017 19913553 15538384 16307917 32600329 26330542 16275660 20704274 21325980 15001357 16293251 33571422 17324930 23904609 23999428 19875381 27353360 18784277 19196961 20146531 21360678 18292230 16207813
CHIP HSP74 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31320752 21549100 23344957 28754656 33658435 32041778 17317785 18436529 21454478 29274099 16169850 12574167 32483383 16554822 30446660 21775628 22824801 14532117 30911017 19913553 15538384 21518764 23764847 21358815 19892702 33619536 16275660 19940151 20704274 21325980 23412384 16293251 26010904 23271055 27708256 33775711 20349136 23410750 29317501 10330192 19648119 17545168 18784277 19196961 20146531 20661446
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
GCR HS90B â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 35124280 27803151
HSP7C HSP71 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 25864199 18457437 22863883 9305631 27684187 22939629 11741305
HSP71 HSP72 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 22939629 33957083
FOXP3 SMAD3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HS90A HSP74 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 27708256 27187154 18620420 16314389 33571422 21360678 18408180 26344197
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
AKT1 HS90A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32707033 16189514 21767636 12176997 31980649 25714412 15843522 29311840 22504172 16027165 29139175 12586360 19356729 10995457
BAG3 HSP71 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 23824909 16713569 10980614 30559338 9873016 26496610 19229298 11527400 33961781 21252941 33957083
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
HSP72 HSP7C â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25036637 31536960 33961781 22939629 29568061
HSP7C BAG2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 18457437 22365833 9873016 33961781 30021884 27684187 26344197 29568061 16207813
HSP7C BAG3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 25416956 23824909 25036637 30559338 9873016 26496610 33961781 21233200 27684187 21423662 29568061
TRAF6 IRAK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22033459 24735611 11397809 19716405 17197697 30872404 8837778 10346818 17785851 11960013 18234474 16951688 16024789 11287640 12034707 21220427 23381138 19166926 24434549 28882891 18056395 11259596 23244239 12496252 22447928 20043910 12566447 11518704 12242293 10920205 10383454 18347055 9374458 31921110 14625308
HSP7C BAG1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17954934 16189514 25416956 28215707 9774640 20675402 14978028 9873016 12874020 10671488 11222862 19800331 25535373 26871637 9305631 11707401 11741305 12297498
BAG1 HSP71 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11231577 14517289 19229298 9305631 11101523 11741305
HS90A GCR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 24949977 8898375 24462205 8621522 10066374 28537252 35124280 9334248 31467278 10903152 20195357 14987994 26804907 16131566 19875381 16087666 15916966 8089152 9195923 8139547 15004035 8645634 12093808 27803151
SMAD1 YAP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PSDE PSMD4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28539385 31235931 30479383 27428775 19781552 32723828 26496610 28821611 17323924 26344197 19412159 33961781 30745168 24121268 22939629 24743594
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HSF1 BAG3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23983126 19006120 20692357
PTEN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
UBE2N UB2V1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16129784 15147900 18678647 25260751 17709375 20613989 16307917 29662619 32659264 18029035 22367539 25548215 29069608 11057907 22939629 29537486 10089880 19549727 18082144 16215985 27173435 33961781 26344197
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
YAP1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19914168 35044719 23431053 21685363
TRAF2 IRF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
SMAD3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26365427 22908322 25065622 18157133 23243069 20937549 19701891
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320