Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KRT17 AGAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT17 ARAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
CCDC85B KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC85B KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CFTR RHOQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15546864 11162552
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
COPS5 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19180539
EEF1G ECH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ECH1 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
EEF1G SNAPIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
STAT5A FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9885561 10512880
GRB2 KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
STAT1 IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24408967 21659501
KRT17 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KRT77 KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT17 KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STAT3 KRT17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21796151
STAT1 KRT17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21796151
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
UCHL1 TRIM21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EGFR TUBA1A â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
BRCA1 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
RYBP HERC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 26186194
EGFR STAT5B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 11751923
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NR3C1 STAT3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CFTR MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
HERC2 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 90000000
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
GRB2 MYH9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20936779 24189400 12577067
JUN STAT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
EGFR STAT5A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
STAT1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10792030 16713569
UCHL1 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32494592 32042339 31980649 20029029
AXIN1 APC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20128690 29045831 29713058 9734785 19131971 10811618 26496610 23277359 10228155 16199882 17510365 22682247 18786926
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
JUN IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22983707 21600798 23125217
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
NR3C1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 8878484 9528750
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
APC JUN â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC JUN â—¼   SHARES_COMPLEX 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
USP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10830280 10358079 12411494 10558875 16729043 17016520 11751923
EGFR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 31980649 10358079 24658140 25402006 18586824 16729043
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
NR3C1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16850320 9804760 1314076 8036015 8890955 8733011
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
STAT5A GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
STAT3 IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22665476 24412612 17363300 16698929 20493732 21949021 21151104 19265112
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
LRRK2 SNAPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23949442
STAT1 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT3 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737