Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ADAM9 PACSIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10531379 5211924
RHOQ ARHGAP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 27481945 31871319
RHOQ ARHGAP26 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 27481945 31871319
CFTR RHOQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15546864 11162552
RAPGEF1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621483 5220979
RHOQ DLC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 27481945 31871319
GNA11 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
RHOQ GOPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15546864 11162552
ITSN1 WASL â—¼   COLOCALIZATION 2.0 0.8 intact 5214632 11584276
NCLN RPL29 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RHOQ PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9799731
RAP1B RAPGEF1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10753869 12006644
STX4 SLC2A4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15753124 20634814
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TRIP10 WAS â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ILK PARVA â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
RHOQ KPCI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 10934474
MRCKA RHOQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15194684 31871319
STX4 STX10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 34079125
STX6 STX10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 34079125
CD44 KPCI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31980649
BORG5 RHOQ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31871319 10490598
PTPRK ADAM9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B STX10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STX10 VTI1B â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CFTR ESYT2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
STX4 STXBP3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PARD6B RHOQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FADD TNFRSF10A â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
VTI1B STX6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27791468 26186194 28514442 34079125
RHOQ PAR6B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 10934474 11162552
BORG1 RHOQ â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 10490598
GOPC RHOQ â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25416956 11162552
CBL ITSN1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBL SH2B2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
STX6 STX4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 25416956 26186194 21516116 28514442 34079125
PAR6B PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 12459187 26186194 14676191 28514442 34079125
BORG4 RHOQ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31871319 10490598
PACSIN3 WASL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CBL SORBS1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PAR6B KPCI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 23439680 32296183 31980649 26496610 23718855 26186194 11260256 14676191 25416956
TGFBR1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12145287
GOPC CFTR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12471024 11707463 31324722 28360110
CRK RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
RHOQ EXOC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12687004
TRIP10 WASL â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STX6 VTI1B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PVRL3 PARD3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16189514 12515806
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PARD3 KPCI â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31980649 12459187 14676191 22883624 34079125
WASL ITSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11584276 18539136
PARD3 PARD6B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PARVA ILK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 23455922 25502805 11694518 17553790 26496610 21516116 22863883 26344197 22441983 15284246 32707033 23877428 12432066 32296183 17353931 25852190 22767580 28514442 25416956 16189514 11331308 26186194
ILK PARVA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STX4 STXBP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL RAPGEF1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 8943292 10753869 8978305 16443220 11466412 8621483 9129019 10907644 18835194 10592173 9374471 10926930 9311917 10339478 11167825 12671687 9344843 9820532
ARHGAP1 RHOF â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16777452 17765681 27481945 31871319
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL RAPGEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL RAPGEF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
SH2B2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11997497 10854852 23331499 15737992 11498022 15031295 17620296 18273061 9989826 10374881 9233773
SORBS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15128873 9447983 17548467 12504111 12765336 11001060
CD44 SLC9A1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16104017 9712871 15090545 8901634 11350981 17050540 15035633
GOPC CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 12471024 16331976 28360110 18754678 17158866 11707463
CRK RAPGEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK RAPGEF1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK RAPGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 8621483 9560161 9122199 17515907 10592173 11870224 9591773 18835194 8943292 7512734 19001122 7806500 20697350 7531694 12054111 19380743 17474147
TNFRSF10A FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11376335 9430228 10894161 10894160 14585074 16189514 9430227 15452120
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
RHOQ ITSN1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 7721814 21454492 17214551 23255595 25678704 19258391 19713215 9857026 24297911
PAK1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17081983 14580336 21481793 23162742 22105362 18071304 20068231 19036346 18669648 20302846 15378014 27285107 28090172 27345717 19165420 14981079 26555075 19651622 19691289 22567403 11719502 25893302 11782491
RHOQ OBSCN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 7721814 21454492 17214551 23255595 25678704 19258391 19713215 9857026 24297911
TGFBR1 PARD6A â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFBR1 PARD6A â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFBR1 PARD6A â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFBR1 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 15761148 25756394 15761153 19114990
RHOQ PREX1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 7721814 21454492 17214551 23255595 25678704 19258391 19713215 9857026 24297911
STX10 RAB9A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258