FGR
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9636140
23109003
|
SYK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9590268
|
LYN
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9636140
23109003
|
ABL1
|
SHANK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
TRIP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
ABL1
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
PRKCA
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10713049
|
HTT
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AKT1
|
PTK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15539407
20606012
|
ESR2
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16549430
17261755
|
PRKCZ
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
18650932
7232391
|
TRIP10
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212318
10713100
|
WAS
|
FGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220415
7565724
|
PRKACA
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
INPP5D
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
32323266
22267732
|
WAS
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7208262
16107303
|
TRIP10
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215944
12456510
|
LYN
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16978534
12473184
|
LYN
|
PRKCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10592173
16713446
|
TGFBR2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16360132
|
MAPK7
|
RPS6KA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12832467
16626623
|
PRKCZ
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667433
17646398
|
PDPK1
|
PRKCZ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
PDPK1
|
PRKCA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
PRKCA
|
RPS6KA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16810323
5218785
|
SYK
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
WBP11
|
TRIP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FNBP1
|
WAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
802.0
|
0.8
|
STRING
|
36370105
|
TRIP10
|
WAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
AKT1
|
GSK3B
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15829723
|
AKT1
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
23552696
|
RHOJ
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10967094
31871319
|
WASL
|
RHOJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25416956
31871319
32296183
|
TUBGCP2
|
TUBGCP3
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
AKT1
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
WASF1
|
ABL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10970852
18559503
|
POT1
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
FGR
|
WAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
FNBP1
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
LYN
|
FGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32707033
31980649
34079125
|
STAT3
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
BMX
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
ABL1
|
ABL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27229929
12569093
15735735
|
TRIP10
|
WASF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
POT1
|
TINF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
GSK3B
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
PRKCA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19836308
|
GSK3B
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22778263
|
FGR
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16787943
11847100
16076903
|
AKAP9
|
TRIP10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
27039663
15047863
|
PDPK1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11438723
11313365
23397142
11278835
14500673
26264872
32876514
27563096
26256536
9368760
12149249
11445557
31467278
11825911
10226025
21775285
10698680
22569334
16189514
|
PRKACA
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
32913128
10187789
15209507
|
STAT3
|
ESR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23295773
21546410
|
ESR2
|
TRIP10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
PDPK1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17496917
15125833
16056267
|
PRKCZ
|
MAPK7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20538799
11158308
|
STAT3
|
PTK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12540842
20929863
19393627
|
TRIP10
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
AKT1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
TERF1
|
TINF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
WAS
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8625410
5221000
|
PTK2B
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
WASL
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31871319
16293614
9422512
10781580
20936779
21311754
10724160
11943145
11331876
15834156
|
TINF2
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10581025
15383534
28514442
21044950
19487455
33961781
15316005
11701125
26496610
16880378
16169070
15133513
26186194
20811636
17589526
25416956
15181449
28216227
|
CDC42
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
TUBGCP3
|
TUBGCP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
TUBGCP4
|
TUBGCP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
TUBGCP4
|
TUBGCP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
TUBGCP5
|
TUBGCP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDC42
|
WAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PRKCZ
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18353303
14657655
11481324
|
AKT1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
99.0
|
1.0
|
Omnipath
|
17428466
15207235
17145710
12052830
10729337
8250835
11756412
11923280
16914735
17623045
16697215
8524413
12054501
20398329
18372248
21506126
20028971
12040186
15808505
16543730
20138985
23331499
21303971
16009706
10385618
20214616
23180781
9373175
16039586
15829723
18988627
16282323
11577096
11035810
18669648
18216173
15169778
12851486
16123141
11882383
23109003
9065430
18691976
22094462
10949026
22710759
11715018
12459251
18636226
17192257
11254732
11278246
20858269
9812896
9582355
15023346
17680028
19369195
7945242
12900420
23552696
18387957
10722653
20832730
18570873
12147701
18505846
17052453
17693255
18218901
|
PRKACA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
16543730
15845746
18691976
19836308
8524413
12054501
16039586
12147701
16522636
11035810
18669648
|
PTK2B
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26274564
10601262
16452634
24931005
|
PXN
|
TUBGCP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
PXN
|
TUBGCP3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TRIP10
|
PXN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
CDC42
|
PXN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
PTK6
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17081983
15572663
15592455
18676874
18083107
7537852
17389395
7493940
7615549
19534553
11774284
15107421
12408869
10823820
16254239
15817476
16094384
19304789
16212419
21423176
15951569
|
ABL1
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7615549
15817476
11774284
16254239
15107421
12408869
15572663
11695992
15592455
16094384
10823820
20841568
16713569
9603926
7537852
|
GRK5
|
SNCB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10852916
|
LCK
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16076903
16787943
17570479
11847100
|
LYN
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12644574
16787943
16912036
16076903
11847100
|
ABL1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8940193
16846476
20841568
|
ABL1
|
DNM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17474147
20841568
19833721
|
ABL1
|
CDK5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
19901323
26944284
15689152
19690332
16497976
24975575
19413330
20841568
18083107
19534553
20068231
19700222
9038181
14757045
23348931
11113134
10896159
18691976
28646794
29063113
24600352
12372285
19369195
18794154
15212693
|
ABL1
|
TRIP10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19631450
20841568
|
ABL1
|
ABL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12569093
15735735
20841568
|
ABL1
|
WASL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
17389395
19901323
16199863
19664994
20068231
18707149
18452278
20146487
20841568
19415658
|
ABL1
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12944467
20841568
|
ABL2
|
WASL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20146487
16199863
20841568
|
PDPK1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11687500
11747822
12670391
15802604
17680028
18802401
19109239
19122654
|
PRKCZ
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11585925
15884057
14560023
16189514
11748077
18353613
11723139
10085094
|
PDPK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
156.0
|
1.0
|
Omnipath
|
15505410
12538620
12176337
19951971
24352480
11752451
19401591
11369519
10698680
10601311
15718470
24950409
20481595
24169049
10570282
16798838
14993273
11500365
9368760
19844585
17680028
7637810
9169478
26256536
7722458
9094314
12750173
11438723
18802401
9252186
23331499
18456494
9104825
10592173
16189514
20361045
18988627
11278835
20163786
20333297
20041157
12808134
19602588
8630736
10207050
11241670
10438924
9868760
25912234
20153221
25582703
11445557
21775285
12149249
14666721
18596232
9512493
23397142
11809791
12167717
21798082
16033886
10679787
16787925
29562639
15550174
21071413
8978681
10833263
19203586
10226025
26937223
14500673
20161206
11136732
11825911
11042193
9642236
22569334
18662999
9736715
12242303
11313365
11598012
11134526
|
PTK6
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20606012
15994200
15539407
|
RET
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12600984
15994200
|
INS
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
29432553
23912456
11679435
23866690
17335965
24646332
23798298
|
AKT1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20016067
23331499
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
PTK2B
|
ASAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12771146
|
CDK5
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22778263
21669867
|
CDC42
|
TUBGCP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
CDC42
|
TUBGCP5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
CDC42
|
TUBGCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
CDC42
|
TUBGCP4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
CDC42
|
TUBGCP6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
CDC42
|
WAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
10360579
10559936
10940259
8643625
9422512
9742969
25502805
10684602
15075243
10511705
15020669
12235133
12769846
8625410
11340065
15361624
16189514
15003621
16293614
20936779
22252508
10934474
11413130
15713627
10747096
11950587
27871158
10724160
10360578
10713100
10467124
10068673
9660763
25758716
11248548
10802735
31515488
18719708
10613909
10461188
|
CDC42
|
WASL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
17145710
10559936
11331876
10940259
9422512
11943145
10511705
15020669
8625410
11340065
10219243
15003621
15834156
16293614
20936779
10934474
11413130
15713627
11950587
10724160
10467124
10781580
11248548
18719708
10613909
10461188
|
CDC42
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23109003
17353362
10733591
10873802
|
CDC42
|
WASF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10360578
8643625
12181570
11052943
15834156
|
STAT3
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
CDK5
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25038288
16651438
19156541
12763138
28114390
16879821
23941877
15096606
26198700
|
CDK5
|
HTT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25799558
16782707
32668197
18691976
15911879
19413330
17611284
|
SYK
|
FGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11672534
15536084
|
FGR
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
12495636
7529876
10593973
|
LCK
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
PTK2B
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9257837
9091579
|
SYK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
8798764
19664994
15536084
8621719
8798676
16497976
25990959
7518561
8845015
16189514
7539035
15659558
|
LCK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11404481
9484840
9344858
18070987
10815799
16189514
10825200
25814554
|
LCK
|
PRKCQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22798961
26090489
17548359
10652356
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18453587
23109003
12495636
17570479
11311138
7529876
10593973
|
PRKCQ
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10652356
15214048
15536066
16606694
17544292
17548359
18784374
19201850
23077238
23433459
23474202
23886063
25960930
|
PRKCQ
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23433459
19201850
23109003
17544292
18784374
15536066
16606694
23886063
26192618
20164171
17548359
17363905
23077238
10652356
25960930
23474202
15214048
|
MAPK9
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20871632
18691976
|
PDPK1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10652356
11687500
11747822
12670391
15214048
15536066
15802604
16606694
17544292
17548359
17680028
18784374
18802401
19109239
19122654
19201850
23077238
23433459
23474202
23886063
25960930
|
RET
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16314505
11481331
15212693
12738763
15302935
|
PDPK1
|
RPS6KA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19369195
10480933
17192257
17906627
|
PDPK1
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
12887331
14500673
11222751
18691976
10075713
20332120
9768361
9748166
17335005
10357815
16189514
11141077
16051884
11781095
10764742
14604996
|
PDPK1
|
PRKCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15209375
11078882
10698939
9889098
|
PDPK1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
16026785
20732331
15481030
22493239
10698939
9707564
8706898
20137943
21774789
17192257
22154087
20481595
12372837
16765046
|
TINF2
|
POT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
10581025
10850490
11349150
15231715
16166375
18680434
18828880
19454690
19965504
22064479
22634377
7502076
9326951
9822378
|
TINF2
|
POT1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
10581025
10850490
11349150
15231715
16166375
18680434
18828880
19454690
19965504
22064479
22634377
7502076
9326951
9822378
|
WRN
|
POT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
PRKACA
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20682772
15966897
17050626
11886862
|
SYK
|
PRKCA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9531509
20068231
12881490
17192257
15583006
|
SYK
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9560226
8816475
9988732
15105428
9727056
10747947
14624447
|
PTK2B
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14963038
|
PTK6
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18083107
17389395
21741923
19534553
7701321
19304789
16568091
15592455
12763138
15951569
20929863
18234692
|
RET
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10918587
9305919
8272872
12626508
15592455
24662939
23331499
17209045
12576423
11350938
18498667
11294897
12244095
16189514
25047660
17761947
9083098
25241761
12637586
8626374
15485908
9566874
11940572
11429593
14551213
11536047
11850821
15212693
9582023
|
WAS
|
RHOJ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
12456725
10967094
32302585
22971344
31871319
26299518
|
SYK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10777558
25416956
21516116
20133729
31515488
16189514
10825200
32296183
|
WRN
|
TINF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
TRIP10
|
TUBGCP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
TRIP10
|
TUBGCP4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
TRIP10
|
TUBGCP5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
TRIP10
|
TUBGCP6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
TRIP10
|
TUBGCP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10467124
10511705
10713100
11395419
11520460
12177428
14707117
15001467
15541654
16293614
16606694
17785506
19741094
21178402
23212475
8625410
|
TUBGCP2
|
TUBGCP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP2
|
TUBGCP5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP3
|
TUBGCP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP3
|
TUBGCP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP3
|
TUBGCP5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP3
|
TUBGCP4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP5
|
TUBGCP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP5
|
TUBGCP4
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
TUBGCP6
|
TUBGCP5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
12616499
15308668
16000375
16887996
17006514
18287025
18802074
22043013
24655141
29021139
|
WRN
|
TRIP10
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.08
|
1.07
|
PKG
|
28854368
|
WRN
|
WRN
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.6
|
3.59
|
PKG
|
28854368
|