Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GNG2 PREX1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GNG2 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17419683 16537363
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT1 MTOR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17611497 18954143
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
SP1 DPYSL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15207709
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 GNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19170076 18414489
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
GNB5 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 17169327
GNB5 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 17169327
GNG3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17419683 16537363
GNG4 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 17169327
GNG4 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 17169327
GNGT1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17419683 16537363
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
PIK3CD PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
RAC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3R2 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638 11733063
PIK3CG RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15009099 23331499
PIK3R2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12515821
PRKACB PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16301320 23109003
PRKACG PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16301320 23109003
PRKX PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16301320 23109003
RICTR PREX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17565979 21339740
RPTOR PREX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17565979 21339740
PIK3CG PIK3R5 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GNB1 PREX1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RAC1 PREX1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27150042 32203420
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RICTR RPTOR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19145465 19446321 21045808 33378666 16962653
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
RICTR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16603397 22337773 21339740 21343617 21795849 22307628 25241761 21177249 15718470 22990118 19402821 25273559 18566587
AKT1 RICTOR â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GNGT2 GNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8636150 19168127 19376773
RICTR MTOR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446321 30865892 18505677 18339839 21045808 22544753 21321085 15467718 34171383 33416177 17386266 17043309 15268862 18030348 19875983 21795849 20978191 23953116 31665642 18570873 33378666 19299511 21177249 22990118 22084251 16919458 23872070 19145465 16962653 25897075 18504440 16603397 18566586 24375676 17277771 22307628 24036451 27043084 22285861 23263282 23297343 16183647 18566587 17565979 19619545 20427287 21343617 17461779 29567957 29059166 21376236 19114562 25273559
MTOR AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11438723 22337773 18505677 21045808 15718470 30639242 19299511 24670654 21177249 22084251 23872070 10910062 18566586 22307628 14970221 25792870 18566587 21343617 25241761 29567957 26293922
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC BZW1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
RAC2 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
PIK3R1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8596638 14665640 11733063
RAC2 PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
SP1 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16814105 19464346 17376651
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AKT1 MTOR â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
MTOR AKT1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 21592956
GNB3 GNGT2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB3 GNGT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB3 GNG11 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB2 GNGT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB4 GNGT2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB5 GNG5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GNB5 GNGT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PIK3CA PIK3R3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CDC42 PREX1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
PIK3CD PIK3R1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
GNB5 GNG2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG13 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG10 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB3 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNGT2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG10 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG11 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG10 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNGT2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG13 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB1 GNG4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB4 GNG4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB4 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB4 GNG3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB4 GNG5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB5 GNG7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB5 GNG3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB5 GNG4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2 GNG2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB3 GNG2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB4 GNG2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNG2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ESR1 GNG2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11689445 27288742 11369763 25587652
GNB1 GNG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNG2 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG2 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23739333 8636150 9789084 10339615 12606627 15889144 15782186 11294873 18611381 10696571 19376773 12782285 19168127
GNB3 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNB2 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG12 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
MTOR AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RICTOR â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RPTOR â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
AKT1 RICTOR â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
MTOR AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 24670654 16697215 11438723 21592956 20398329 17461779 18372248 21177249 21045808 20338997 15808505 16221682 20138985 20489726 15899889 20214616 8978681 21474067 14970221 19203586 17660512 15718470 19568798 20333297 23006971 15169778 25241761 18566586 19720745 17517883 18925875 22084251 10949026 14761976 11715018 19143635 17277771 18636226 10910062 15047712 9812896 18505677 21343617 19844585 17680028 19151919 18566587 9736715 23872070 10722653 20832730 18570873 17013611 17052453 12408816 15364915 11274345
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 RICTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 21177249 20338997 19402821 15808505 20138985 21339740 16603397 20214616 21474067 16919458 15718470 19568798 17545609 15169778 18566586 25241761 19720745 18925875 22990118 10949026 11715018 19143635 18636226 18411301 9812896 21343617 17680028 19151919 18566587 10722653 20832730 18570873 17052453 12408816 11274345
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 18000759 21157483 11756412 11923280 16697215 20398329 17461779 18372248 15808505 20138985 20214616 19568798 15169778 19720745 17517883 10949026 11715018 19143635 17277771 18636226 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
ESR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11029009 11689445 16169518 23065768 16713569
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
GNB1 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNB4 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNB5 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG10 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG11 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG13 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG3 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG4 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG5 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG7 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNG8 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
GNGT1 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
MYC MTHFD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 12808131 18414489
RAC1 MTOR â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 MTOR â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RAC1 MTOR â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RAC1 MTOR â—¼   DOWN_REGULATES ✅ - 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
RPTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
PIK3R3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8596638 22402981 9415396 11733063 26496610 25814554
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
PIK3CB PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
PIK3R1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9113989 8596638 21827948 12147247 11733063 22020336 24165795 31031754 14665640
PIK3CG PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PIK3R5 PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16847462 17430994 21640127 12297047 21736902 11955434
RHOQ PREX1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 7721814 21454492 17214551 23255595 25678704 19258391 19713215 9857026 24297911
PRKACA PREX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 16301320 32661198 26797121 22242915
PREX1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21172654 15611338 32203420 11955434 15967165 27150042 12829230
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
RAC1 RICTOR â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 RPTOR â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RPTOR â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RICTOR â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 RPTOR â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RPTOR â—¼   DOWN_REGULATES ✅ - 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025