Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLCB3 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
B2M RAB9A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ABCE1 RPL37A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
AFG3L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AP3M1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CANX MRPL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCDC47 NCLN â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCDC47 RPL37A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MCM5 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CHCHD3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
EGFR KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20692258 7987951
ETF1 RPL37A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FBL MYO1C â—¼   COLOCALIZATION 2.0 0.8 intact 16514417 5218407
FSCN1 RAB1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VPS13A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHEB HIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT HIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22835334 8385344
NCLN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PACS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
PRKACA ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCLN RPL37A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PTPRJ PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6671848 10821867
PTPRJ PDGFRB â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6671848 10821867
RHOA PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 14681219
PRKACA RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAB2A PRKCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14570876
RHOA RDX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35267019
ARMC6 MCU â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C1QBP DDX50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
C1QBP DDX54 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
GBF1 COPG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30567983 19039328
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR EXOC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
RHOA FAT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
NEDD8 MCM5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18274552 18247557
RAB1A RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
VAPA RAB5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RPL37A SRP9 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIP1R PICALM â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MSH3 PCNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
C1QBP PHB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27025967 22904065 32877691
FBL GAR1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
EGFR EMD â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24797263 28065597 20937808
RAB11B RAB8A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
AAAS NDC1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PICALM PIK3C2A â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RHEB MTOR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18550814 16098514 25351248 15854902 15878852 16915281 33157014 15772076
FLOT1 RAB5C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
CYFIP1 NCKAP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
NMD3 RPL37A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PFKM PFKP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EGFR PDCD6IP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FYN CD44 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
RAB5C RAB1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RAB11B RAB1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
DAG1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11724572 17474147
VAPA EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25754235 31980649 23956138 20029029
PTPRJ EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19167335 19836242 9115287
RAB2A PHB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PCNA MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
HIP1R HIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11063258 11889126 33961781 28514442
HLA-C PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 21339333 9605119
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
FBL UTP20 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
LAMTOR1 MTOR â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KRIT1 RAP1B â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RHOA ROCK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PVRL3 PARD3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16189514 12515806
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ROCK1 RHOA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31871319 14660612 31431478 8816443 21281639 8798490 12773565
CCM2 KRIT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
MPZL1 PTPN11 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
CYFIP1 NCKAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MTOR RHEB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA FANCI â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCI â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
PRKACA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 28615442 9660757 10893237
CAPZB DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
PDCD6IP EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 31980649 15456872 12771190 24658140 15557335 25402006
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
PTPRJ EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19836242 9115287 19167335
EGFR EPB41 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 2171679 1647028
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
PDGFRB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 1696179 7685273 7687537 16713569 1661130 9425276
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
FYN ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16387660 17053785
PTPN11 MPZL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 10681522 9792637 11751924 15588985 16189514
RHEB MTOR â—¼   UP_REGULATES ✅ 7.0 1.0 ACSN 12906785 16636147 17604271 18466115 19022819 19143635 23087689
RHEB MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 18670866 18075516 18550814 16631613 18466115 16915281 23331499 15772076 16098514 20006481 15878852 21071413 23272152 19299511 15854902 19487463 20226003 19143635 17604271 16636147 17470430 12906785
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
PTPRJ PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 10391677 7876130 14966296 19167335 8940081 12062403 10821867 1691440
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811
RHOA PKN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18835241 9446575 9121475 8910519
PRKACA RAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8463283 19651783 27760305 12089143 1551424 90343822
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
ROCK1 RDX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17447891 8522586 9456324 9287351 10970850 12778124 12045227 20068231 12802084 7579708 10047517 8527459
RHOA ROCK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11698448 11729192 11739775 11992112 12194823 12361600 12740575 14657501 14744429 15761148 17517963 18037882 18423981 20535745 21178402 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
RHOA ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 12361600 25010901 23151663 7479854 27048821 22949611 21281639 26885855 8798490 12727213 17673200 11729192 8816443 10592173 11698448 27066895 11739775 11992112 20535745 18423981 24857661 21178402 23109003 9660866 9822605 17517963 14660612 15774750 12740575 14744429 9535835 12773565 15761148 24919149 26192618 9362522 18037882 14657501 12194823
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368